Acute Pulmonary Embolism: An unseen villain in COVID-19.
PMID: 32425236 [PubMed - as supplied by publisher] (Source: Indian Heart J)
Source: Indian Heart J - May 16, 2020 Category: Cardiology Authors: Agstam S, Vijay J, Gupta A, Bansal S Tags: Indian Heart J Source Type: research

Cardiological society of India position statement on COVID-19 and heart failure.
ar PG, Khanna NN, Majumder B, Mandal M, Meena CB, Naik N, Narain VK, Pathak LA, Ray S, Roy D, Sarma D, Shanmugasundaram S, Singh BP, Tyagi SK, Venugopal K, Wander GS, Yadav R, Das MK Abstract The COVID 19 global pandemic has engulfed humanity with a huge impact on health systems across the world. Many patients develop myocardial injury which can lead to significant cardiovascular complications including HF. This will require aggressive management strategies which are evolving. Guideline directed drug therapy including ACEI/ARB/ARNI is to be continued in patients with pre-existing HF. Long-term cardiovascular effec...
Source: Indian Heart J - May 13, 2020 Category: Cardiology Authors: Harikrishnan S, Mohanan PP, Chopra VK, Ambuj R, Sanjay G, Manish B, Chakraborty RN, Chandra S, Chattarjee SS, Chopra HK, Mathew C, Deb PK, Goyal A, Goswami KC, Gupta R, Guha S, Gupta V, Hasija PK, Wardhan H, Jabir A, Jayagopal PB, Kahali D, Katyal VK, Ker Tags: Indian Heart J Source Type: research

Continue ACE inhibitors/ ARB'S till further evidence in Coronavirus disease 2019 (COVID-19).
PMID: 32405087 [PubMed - as supplied by publisher] (Source: Indian Heart J)
Source: Indian Heart J - May 7, 2020 Category: Cardiology Authors: Bansal S, Agstam S, Gupta A, Gupta P, Isser HS Tags: Indian Heart J Source Type: research

Acute myocardial infarction in pregnancy: Current diagnosis and management approaches.
Abstract Acute myocardial infarction during pregnancy is a very uncommon condition; atherosclerotic coronary artery disease is by far the most common cause of an acute coronary syndrome in the general population. The causes of an acute coronary syndrome in the pregnant patient are wide and varied. This has important implications with respect to the diagnosis of the etiology and the subsequent management of the cause of the acute coronary syndrome. There are a number of diagnostic tools for the diagnosis of coronary artery disease but it is important to understand their role in pregnant patients. Spontaneous corona...
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Edupuganti MM, Ganga V Tags: Indian Heart J Source Type: research

Standardizing hypertension management in a primary care setting in India through a protocol based model.
Abstract Hypertension is a leading cause of death in India. Control rates of hypertension are abysmal, even for people on treatment. There are a number of barriers to adequate control of hypertension in India, including therapeutic inertia and the lack of a systematic, simplified approach. Standardizing hypertension management through an evidence based model that sets thresholds for diagnosis, treatment goals, follow up intervals and choice of drugs can lead to improved management of hypertension in an individual hospital or health system. In this paper, we summarize the evidence for such a model, and adapt it to ...
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Satish P, Khetan A, Raithatha S, Bhende P, Josephson R Tags: Indian Heart J Source Type: research

Intermediate term outcome after electrogram guided segmental ostial pulmonary vein isolation using an 8  mm tip catheter for paroxysmal atrial fibrillation.
CONCLUSION: Conventional RF ablation using PV potential-based mapping and ablation with 8 mm tip catheters is safe for patients with PAF. The intermediate term outcome is satisfactory and cost-effective in our setting with limited resources. PMID: 32035520 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Pawar P, Vadivelu R, Bachani N, Jeyashree K, Sharma R, Rathi C, Jadwani J, Bera D, Lokhandwala Y Tags: Indian Heart J Source Type: research

Clinical characteristics and outcome in patients with a delayed presentation after ST-elevation myocardial infarction and complicated by cardiogenic shock.
CONCLUSION: Patients with a delayed presentation after CS-STEMI were younger and more likely to have single-vessel disease. We found a high in-hospital mortality of 42.9%. Appropriate randomized studies are required to evaluate the optimal treatment strategies in these patients. PMID: 32035521 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Sharma YP, Krishnappa D, Kanabar K, Kasinadhuni G, Sharma R, Kishore K, Mehrotra S, Santosh K, Gupta A, Panda P Tags: Indian Heart J Source Type: research

Fragmented QRS complex is an independent predictor of plaque burden in patients at intermediate risk of coronary artery disease.
Abstract OBJECTIVE: We aimed to evaluate the relationship between fragmented QRS complex and plaque burden in patients presented with typical chest pain and deemed to have intermediate pretest probability of CAD using coronary computed tomography angiography (CCTA). METHODS: We studied electrocardiograms (ECGs) obtained from 172 subjects (47.5 ± 9.5 years, 125 were men) presented with chest pain and had intermediate pretest probability for CAD. The presence was found and evaluation of CAD was performed with CCTA. RESULTS: Seventy four (43%) of the study cohort had CCTA-documented CAD. Me...
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Mahfouz RA, Arab M, Abdelhamid M, Elzayat A Tags: Indian Heart J Source Type: research

Prevalence and RIsk factors for Silent Myocardial ischemia (PRISM): A  clinico observational study in patients of type 2 diabetes.
CONCLUSION: Silent myocardial ischemia is highly prevalent at about one in four asymptomatic diabetic patients. An increased CIMT can be a surrogate marker of higher coronary risk amongst these asymptomatic diabetics. PMID: 32035523 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Prasad DS, Kabir Z, Revathi Devi K, Peter PS, Das BC Tags: Indian Heart J Source Type: research

Assessment of right ventricular systolic function in heart failure with preserved, reduced and mid-range ejection fraction.
Abstract BACKGROUND: Few studies have evaluated the right ventricle systolic function in different categories of heart failure despite its effect on outcomes. METHODS AND RESULTS: Single-centre, cross-sectional study included 150 patients, 50 patients in each category of HF: group I, preserved; group II, mid-range; group III, reduced ejection fraction. Left ventricular systolic function was assessed by 3D echo, and right ventricular systolic function was assessed by fractional area change (FAC), tricuspid annular plane systolic excursion (TAPSE), tissue Doppler image (TDI), and global longitudinal strain (GLS...
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Mostafa S Tags: Indian Heart J Source Type: research

Coronary artery size in North Indian population - Intravascular ultrasound-based study.
Abstract OBJECTIVE: The coronary artery dimensions have important diagnostic and therapeutic implications in management of coronary artery disease (CAD). There is paucity of data on the coronary artery size in the Indian population as measured by intravascular ultrasound (IVUS). METHODS: A total of 303 patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) with intravascular ultrasound underwent analysis along with quantitative coronary angiography (QCA). Of the 492 proximal coronary segments; 221 relating to left main (LM), 164 to left anterior descending artery (LAD)...
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Reddy S, Kumar S, Kashyap JR, Rao R, Kadiyala V, Reddy H, Kaur N, Ramalingam V, Kaur J Tags: Indian Heart J Source Type: research

Clinical and angiographic profile of very young adults presenting with first acute myocardial infarction: Data from a tertiary care center in Central India.
Abstract Acute myocardial infarction (AMI) is afflicting young individuals more frequently nowadays. The present study was planned to evaluate the clinical and angiographic profile in adults aged less than 30 years, presenting with first AMI as data from Central India is very scarce. This cross-sectional study included 41 patients of STEMI with a mean age of 27 ± 2.8 years. Risk factors were male gender (95.1%), dyslipidemia (51.2%), tobacco consumption (48.8%), obesity (34.1%), and smoking (29.3%). Anterior wall myocardial infarction (AWMI) was the most common presentation (82.9%) with ...
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Deshmukh PP, Singh MM, Deshpande MA, Rajput AS Tags: Indian Heart J Source Type: research

Incidence and impact of ischemic and hemorrhagic stroke after left ventricular assist device implantation: A nationwide study.
This study aims to analyze the incidence and short-term outcomes associated with stroke (ischemic and hemorrhagic) after implantation of LVAD. METHODS: Study cohorts were identified from the National Inpatient Sample database from January 2009 to September 2015 using the International Classification of Diseases, Ninth Revision codes. The primary outcome was an incidence of stroke, and secondary outcomes were the associated mortality, length of stay, and cost of hospitalization. A multivariate logistic regression analysis was performed to analyze adjusted in-hospital mortality. RESULTS: Use of LVADs increased sign...
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Thakkar S, Rupareliya C, Doshi R Tags: Indian Heart J Source Type: research

Medical referrals in private practice: Need to keep the fine fabric intact.
PMID: 32035528 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - September 1, 2019 Category: Cardiology Authors: Sadananda Naik B Tags: Indian Heart J Source Type: research

Sex differences in 30-day readmission rates, etiology, and predictors after transcatheter aortic valve replacement.
Abstract BACKGROUND: The aim of this study is to analyze sex-specific readmission rates, etiology, and predictors of readmission after transcatheter aortic valve replacement (TAVR). Readmissions after TAVR are common, contributing to increased health care utilization and costs. Many factors have been discovered as predictors of readmission; however, sex-specific disparities in readmission rates are limited. METHODS: Between January 2012 and September 2015, adult patients after TAVR were identified using appropriate international classifications of diseases, ninth revision, clinical modification from the Natio...
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Doshi R, Taha M, Dave M, Desai R, Gullapalli N Tags: Indian Heart J Source Type: research

A prospective study of contrast preservation using ultra-low contrast delivery technique versus standard automated contrast injector system in coronary procedures.
Abstract BACKGROUND: We aimed to assess the decrease in contrast media volume (CMV) with ultra-low contrast delivery technique (ULCD) developed at our institution versus the usual automated contrast injector system (ACIS) contrast delivery in coronary procedures. METHODS: We analyzed the amount of contrast given in the consecutive 204 patients of the operators who use ULCD technique versus consecutive 200 patients of the other operators who use ACIS without ULCD technique for coronary angiograms and/or percutaneous coronary interventions (PCIs) from May 2017 to July 2018 at our center. We calculated the mean ...
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Stys A, Gedela M, Bhatnagar U, Petrasko M, Dawoud H, Malinski T, Stys T Tags: Indian Heart J Source Type: research

CHA2DS2-VASc score as a novel predictor for contrast-induced nephropathy after percutaneous coronary intervention in acute coronary syndrome.
CONCLUSION: In patients with ACS undergoing PCI, CHA2DS2-VASc score can be used as a novel, simple, and a sensitive diagnostic tool for the prediction of CIN. PMID: 31779857 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Chaudhary AK, Pathak V, Kunal S, Shukla S, Pathak P Tags: Indian Heart J Source Type: research

Prevalence of hypertension among Indian adults: Results from the great India blood pressure survey.
CONCLUSION: There is a high prevalence of hypertension, with almost one in every three Indian adult affected. PMID: 31779858 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Ramakrishnan S, Zachariah G, Gupta K, Shivkumar Rao J, Mohanan PP, Venugopal K, Sateesh S, Sethi R, Jain D, Bardolei N, Mani K, Kakar TS, Kidambi B, Bhushan S, Verma SK, Bhargava B, Roy A, Kothari SS, Gupta R, Bansal S, Sood S, Nath RK, Tyagi S, Gupta MD, Tags: Indian Heart J Source Type: research

Duration of in-hospital cardiopulmonary resuscitation and its effect on survival.
CONCLUSION: Our study shows that CPR duration is inversely associated with the establishment rates of ROSC. Most of the benefits of CPR can be achieved in the first 15 min, and a further increase in the duration of CPR provides a minimal gain. Still, survival was achievable till 38 min in some cases, and the ideal duration of resuscitation should remain a bedside decision taking into consideration the whole clinical picture. PMID: 31779859 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Cheema MA, Ullah W, Abdullah HMA, Haq S, Ahmad A, Balaratna A Tags: Indian Heart J Source Type: research

Orthostatic hypotension is associated with new-onset atrial fibrillation: Systemic review and meta-analysis.
Abstract INTRODUCTION: Orthostatic hypotension (OH) is common among elderly patients. Its presence may herald severe underlying comorbidities and be associated with a higher risk of mortality. Interestingly, recent studies suggest that OH is associated with new-onset atrial fibrillation (AF). However, a systematic review and meta-analysis of the literature has not been performed. We assessed the association between AF and OH through a systematic review of the literature and a meta-analysis. METHODS: We comprehensively searched the databases of MEDLINE and EMBASE from inception to November 2018. Published pros...
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Prasitlumkum N, Kewcharoen J, Angsubhakorn N, Chongsathidkiet P, Rattanawong P Tags: Indian Heart J Source Type: research

A milestone in prediction of the coronary artery dimensions from the multiple linear regression equation.
Abstract BACHGROUND /AIM: Coronary artery imaging is one of the most commonly used diagnostic methods. We aimed to investigate whether there is a correlation between left main coronary artery (LMCA), left anterior descending artery (LAD) and left circumflex artery (LCx) artery dimensions in normal cases and a possibility to express the coronary dimensions by multiple linear equations. MATERIALS AND METHODS: Images of coronary angiograms of 925 normal cases selected from 3855 cases made up the study population (515 men and 410 women; age range, 30-75 years). The mean age of the patients was 55.50 ±...
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Divia Paul A, Ashraf SM, Ezhilan J, Vijayakumar S, Kapadiya A Tags: Indian Heart J Source Type: research

Incidence and predictors of super-response to cardiac resynchronization therapy.
CONCLUSION: In our study, 27.6% of patients were super-responders, and a diagnosis of dilated cardiomyopathy, absence of a prior history of MI and prior RV apical pacing predicted a super-response to CRT. PMID: 31779862 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Rohit MK, Krishnappa D Tags: Indian Heart J Source Type: research

Cardiovascular manifestations of people living with HIV/AIDS: Report from a hot spot in eastern India.
Abstract OBJECTIVE: To study the profile and characteristics of cardiovascular abnormalities among patients living with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) at a tertiary care hospital in India. The association of cardiovascular abnormalities with the CD4 count and disease stages, according to the World Health Organization (WHO) classification, was also analyzed. METHODS: A total of 200 patients with HIV/AIDS were compared with 50 healthy controls. All patients underwent blood investigations, chest X-ray, electrocardiography, and echocardiography. RESULTS: The mean...
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Mishra TK, Mishra SK, Singh S Tags: Indian Heart J Source Type: research

Therapeutic experience of ticagrelor in Indian patients with acute coronary syndrome: A non-interventional, prospective, and observational study.
CONCLUSION: Ticagrelor has been used across ACS types and in different management strategies in real world settings in India. The incidence of clinical events was lower as compared with data in literature. ClinicalTrials.gov Identifier: NCT02408224. PMID: 31779864 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Sawhney JPS, Dalal J, Mullasari A, Bansal S, Kahali D Tags: Indian Heart J Source Type: research

Morbidity After cardiac surgery under cardiopulmonary bypass and associated factors: A retrospective observational study.
CONCLUSION: The appropriate patient management strategy can be tailored based on the personal attributes, surgery type, and blood lactate level for individual patients undergoing cardiac surgery to reduce the likelihood of postoperative complications, ICU LOS, and hospital LOS. PMID: 31779865 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Patra C, Chamaiah Gatti P, Panigrahi A Tags: Indian Heart J Source Type: research

Evaluation of intracoronary blood from obstructive vessel in patients of ST-elevation myocardial infarction undergoing PPCI.
CONCLUSION: The evaluation of intracoronary blood provides no additional information regarding the prognosis and short-term (30-day) outcome of the patients when compared with peripheral blood. However, there was a significant intracoronary hyperlactatemia in patients presenting late after symptom onset. SBP was also significantly less in patients with high intracoronary lactate, which signifies that predominant cause of hyperlactatemia was systemic hypoperfusion rather than local increase in lactate levels. PMID: 31779866 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Kumar S, Wander GS, Singh B, Kansal M, Mohan B, Aslam N, Chabbra ST, Goyal A, Kumar S Tags: Indian Heart J Source Type: research

Permanent HIS  bundle Pacing Feasibility in Routine Clinical Practice: Experience from an Indian Center.
Permanent HIS bundle Pacing Feasibility in Routine Clinical Practice: Experience from an Indian Center. Indian Heart J. 2019 Jul - Aug;71(4):360-363 Authors: Sarkar R, Kaur D, Subramanian M, Yalagudri S, Sridevi C, Devidutta S, Bera D, Narasimhan C Abstract There is a paucity of experience regarding His bundle pacing (HBP) at laboratories initially attempting the procedure, especially in the Indian scenario. Patient who underwent HBP were selected for pacing therapy or in lieu of cardiac resynchronization therapy (CRT) at a single center. Among 22 patients attempted, 19 patients underwent success...
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Sarkar R, Kaur D, Subramanian M, Yalagudri S, Sridevi C, Devidutta S, Bera D, Narasimhan C Tags: Indian Heart J Source Type: research

Atherosclerostic cardiovascular disease risk score: Are Indians underestimating the risk of cardiovascular disease?
PMID: 31779868 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - July 1, 2019 Category: Cardiology Authors: Kumar A, Shariff M Tags: Indian Heart J Source Type: research

The saturated fat Controversy: Finding calmness in chaos.
PMID: 31543190 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Gupta MD, Girish MP, Yadav R Tags: Indian Heart J Source Type: research

Lipoprotein(a): An underrecognized genetic risk factor for malignant coronary artery disease in young Indians.
Abstract Malignant coronary artery disease (CAD) refers to a severe and extensive atherosclerotic process involving multiple coronary arteries in young individuals (aged
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Enas EA, Varkey B, Dharmarajan TS, Pare G, Bahl VK Tags: Indian Heart J Source Type: research

The Gene  Polymorphism of Angiotensin-Converting Enzyme Intron Deletion and Angiotensin-Converting Enzyme G2350A in Patients With Left Ventricular Hypertrophy: A Meta-analysis.
CONCLUSIONS: Our meta-analysis reveals that the D allele of ACE I/D and the A allele of ACE G2350A are associated with increasing the risk of left ventricular hypertrophy. PMID: 31543192 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Fajar JK, Pikir BS, Sidarta EP, Berlinda Saka PN, Akbar RR, Heriansyah T Tags: Indian Heart J Source Type: research

Guidelines for the management of common congenital heart diseases in India: A consensus statement on indications and timing of intervention.
ar K, Marwah A, Mishra S, Mohanty SR, Murthy KS, Koneti NR, Suresh PV, Radhakrishnan S, Rajashekar P, Ramakrishnan S, Rao N, Rao SG, Reddy CHM, Sharma R, Shivaprakasha K, Subramanyan R, Suresh Kumar R, Talwar S, Tomar M, Verma S, Raju V Abstract INTRODUCTION: A number of guidelines are available for management of congenital heart diseases from infancy to adult life. However, these guidelines are for patients living in high-income countries. Separate guidelines, applicable to Indian children, are required when recommending an intervention for congenital heart diseases, as often these patients present late in t...
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Saxena A, Relan J, Agarwal R, Awasthy N, Azad S, Chakrabarty M, Dagar KS, Devagourou V, Dharan BS, Gupta SK, Iyer KS, Jayranganath M, Joshi R, Kannan BRJ, Katewa A, Kohli V, Kothari SS, Krishnamoorthy KM, Kulkarni S, Kumar RM, Kumar RK, Maheshwari S, Mano Tags: Indian Heart J Source Type: research

Early thrombolysis is associated with decreased operative mortality in postinfarction ventricular septal rupture.
CONCLUSIONS: Preoperative thrombolysis is associated with decreased odds of operative and overall mortality after surgical repair in PMIVSR patients. PMID: 31543194 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Dogra N, Puri GD, Thingnam SKS, Arya VK, Kumar B, Mahajan S, Verma M Tags: Indian Heart J Source Type: research

Cardiac resynchronization therapy in patients with heart failure and moderately reduced ejection fraction: Could it trigger a super-response?
The objective of the study is to evaluate the effects of CRT in optimally treated patients with New York Heart Association (NYHA) classes II-IV, LVEF of 36-45%, and left bundle branch (LBBB), including clinical, structural and biochemical response. METHODS: A selected group of HF patients have been implanted with CRT-P devices and were followed up for 6 months at 4, 12 and 24 weeks. Clinical assessment included NYHA class, quality of life and 6-min walk distance (6 MWD) test. Echocardiographic assessment included LV dimensions and function and left atrial volume. Serum N-terminal pro b-type natriuretic peptide (NT-Pro...
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Tawfik Ghanem M, Allam LE, Samir Ahmed R Tags: Indian Heart J Source Type: research

Facilitators and barriers of heart failure care in Kerala, India: A qualitative analysis of health-care providers and administrators.
CONCLUSIONS: Key themes emerged regarding heart failure care in Kerala in the context of a health system that is increasingly emphasizing health-care quality and safety. Targeted in-hospital quality improvement interventions for heart failure should account for these themes to improve cardiovascular outcomes in the region. PMID: 31543196 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Agarwal A, Davies D, Goenka S, Prabhakaran D, Huffman MD, Mohanan PP Tags: Indian Heart J Source Type: research

Clinical profile and one-year survival of patients with heart failure with reduced ejection fraction: The largest report from India.
CONCLUSIONS: This represents the largest single-center data of HF patients reported so far and the largest study describing clinical outcomes from HF patients in India. Our patients were younger, had high proportion of CAD, and there was higher usage of beta-blockers. Despite this, the one-year mortality was substantial. Given the enormous magnitude of HF burden in India and the paucity of information on this subject, these findings should be of help in identifying key problem areas and potential solutions for management of HF in India. PMID: 31543197 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Chopra VK, Mittal S, Bansal M, Singh B, Trehan N Tags: Indian Heart J Source Type: research

Impairment of left and right ventricular longitudinal strain in asymptomatic children with type 1 diabetes.
Abstract AIM: The relationship between type 1 diabetes (T1DM) and cardiac function in children is not well established. The purpose of this study was to investigate whether children and adolescents with T1DM present early asymptomatic abnormalities of left ventricular (LV) and right ventricular (RV) function. In addition, we evaluated the relationship of any such abnormalities with glycemic control and diabetes duration. METHODS: This was a prospective study. Standard echocardiography, tissue Doppler imaging, and two-dimensional strain analysis were performed prospectively in 52 children with T1DM. The result...
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Zairi I, Mzoughi K, Kamoun S, Moussa FB, Rezgallah R, Maatoug J, Mazigh S, Kraiem S Tags: Indian Heart J Source Type: research

Comparison of three-dimensional echocardiography and speckle tracking echocardiography in quantification and mapping of intraventricular mechanical dyssynchrony.
Abstract OBJECTIVES: The aim of the study is to compare two advanced methods of evaluation of left ventricular mechanical dyssynchrony (LVMD), the speckle tracking echocardiography (STE) and the three-dimensional echocardiography (3DE). METHODS: One hundred thirty-six subjects, with or without LV dysfunction and with or without bundle branch block (BBB), were included in this study, designed to investigate agreement between magnitude and spatial pattern of LVMD as assessed by 3DE and STE. The frequency and severity of LVMD and localization of most asynchronous segments were compared. RESULTS: Both 3DE an...
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Bhambhani A, Mathew A Tags: Indian Heart J Source Type: research

Genetic variants of chromosome 9p21.3 region associated with coronary artery disease and premature coronary artery disease in an Asian Indian population.
CONCLUSION: Our study suggests that SNPs at the 9p21 risk locus may be used to generate a reliable genetic risk score along with markers at other loci. PMID: 31543200 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Kalpana B, Murthy DK, Balakrishna N, Aiyengar MT Tags: Indian Heart J Source Type: research

Isolated diastolic hypertension and its risk factors in semi-rural population of South India.
CONCLUSION: There is a significant prevalence of IDH below 50 years of age in the semiurban population of South India. As IDH in young and middle age is known to be associated with increased risk of cardiovascular events and end organ involvement, it highlights need for study and development of effective IDH management strategies to reduce associated morbidity and mortality. PMID: 31543201 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Mittal C, Singh M, Bakhshi T, Ram Babu S, Rajagopal S, Ram CVS Tags: Indian Heart J Source Type: research

Clinical significance of bendopnea in heart failure-Systematic review and meta-analysis.
Abstract BACKGROUND: Bendopnea is a symptom mediated by increased ventricular filling pressure during bending forward. Presence of bendopnea in patients can be easily evaluated without additional maneuver in several countries whose norms, habits, culture, and occupation relates to a higher frequency of bending forward. This information may prove valuable in routine clinical practice. We aimed to analyze the latest evidence on bendopnea in order to further define the clinical significance of this symptom. METHODS: We performed a comprehensive search on bendopnea in heart failure from inception up until January...
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Pranata R, Yonas E, Chintya V, Alkatiri AA, Budi Siswanto B Tags: Indian Heart J Source Type: research

Coronary artery disease is associated with valvular heart disease, but could it Be a predictive factor?
This study was conducted to evaluate the prevalence of significant coronary artery disease (CAD) in patients with severe valvular heart disease (VHD) and the association between these two cardiac entities. Our research aims to introduce the theory of a possible causal relationship. METHODS: A retrospective study was conducted on 1308 consecutive patients who underwent surgery for severe VHD in the cardiovascular department of Notre-Dame de Secours University Hospital (NDSUH) between December 2000 and December 2016. According to transthoracic echocardiography, patients were divided into 4 groups: patients with severe a...
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Matta A, Moussallem N Tags: Indian Heart J Source Type: research

Trial sequential analysis of studies comparing the frequency of target-vessel revascularization with drug-coated balloons as compared with second-generation drug-eluting stents in coronary in-stent restenosis: Have we generated enough evidence in the field?
PMID: 31543204 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - May 1, 2019 Category: Cardiology Authors: Kumar A, Shariff M Tags: Indian Heart J Source Type: research

Aspirin for primary prevention: Is this the end of the road?
This article reviews the history of aspirin through the last two decades, with special emphasis on these new trials. PMID: 31280821 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - March 1, 2019 Category: Cardiology Authors: Singal AK, Karthikeyan G Tags: Indian Heart J Source Type: research

Prevalence of familial hypercholesterolemia in premature coronary artery disease patients admitted to a tertiary care hospital in North India.
CONCLUSION: FH prevalence is high among patients with premature CAD admitted to a cardiac unit. To detect patients with FH, routine screening with simple criteria such as family history of premature CAD combined with hypercholesterolemia, and a DLCN criteria score>5 may be effectively used. PMID: 31280822 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - March 1, 2019 Category: Cardiology Authors: Sawhney JPS, Prasad SR, Sharma M, Madan K, Mohanty A, Passey R, Mehta A, Kandpal B, Makhija A, Jain R, Mantri RR, Vivek BS, Manchanda SC, Verma IC Tags: Indian Heart J Source Type: research

Incidence, predictors, and gradation of upper extremity venous obstruction after transvenous pacemaker implantation.
PMID: 31280823 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - March 1, 2019 Category: Cardiology Authors: Shenthar J, Padmanabhan D, Banavalikar B, Parvez J, Vallapil SP, Singha I, Tripathi V Tags: Indian Heart J Source Type: research

Effect of morphine use on oral P2Y12 platelet inhibitors in acute myocardial infarction: Meta-analysis.
Abstract BACKGROUND: Morphine is the recommended analgesic in acute myocardial infarction (AMI). This recommendation has come under scrutiny because of possible slow uptake of oral antiplatelet agents. OBJECTIVE: We performed a meta-analysis of all available studies in AMI patients treated with prasugrel or ticagrelor (P2Y12 inhibitors) that reported use of morphine prior to loading the antiplatelet agents to critically assess the safety of co-administration of morphine and the newer P2Y12 inhibitors. METHODS: Several sources were searched from inception to December 2017 with inclusion of eight stud...
Source: Indian Heart J - March 1, 2019 Category: Cardiology Authors: Vaidya GN, Khan A, Ghafghazi S Tags: Indian Heart J Source Type: research

Incidence and predictors of forearm hematoma during the transradial approach for percutaneous coronary interventions.
CONCLUSIONS: Forearm hematoma following TRA-PCI occurs in about 10% patients. Most hematomas occur near the puncture area. The independent predictors for hematoma formation are age, body mass index, multiple puncture attempts, intensive antiplatelet therapy, and multiple catheter exchanges. PMID: 31280825 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - March 1, 2019 Category: Cardiology Authors: Garg N, Umamaheswar KL, Kapoor A, Tewari S, Khanna R, Kumar S, Goel PK Tags: Indian Heart J Source Type: research

Door-to-Needle Time in Myocardial Infarction: Small Steps, Huge Dividends.
Abstract The Himachal Pradesh acute coronary syndrome registry highlighted a prehospital delay of 780 min. Additional door-to-needle time delay by 1 h increases the hazard ratio of death by 20%. We conducted a retrospective (group 1) and a prospective (group 2) analysis of 63 patients each to measure the impact of a fast-track protocol in the emergency department (ED) on the door-to-needle time in ST-elevation myocardial infarction (STEMI). The fast-track protocol involved zero cost to the hospital and saved 63 precious door-to-needle minutes for patients with STEMI. Thrombolysis in ED can save 33 precio...
Source: Indian Heart J - March 1, 2019 Category: Cardiology Authors: Chauhan V, Negi BD, Sharma G Tags: Indian Heart J Source Type: research

The report on the Indian coronary intervention data for the year 2017-National Interventional Council.
PMID: 31280827 [PubMed - in process] (Source: Indian Heart J)
Source: Indian Heart J - March 1, 2019 Category: Cardiology Authors: Arramraju SK, Koganti S, Janapati R, Emmareddy SK, Mandala GR Tags: Indian Heart J Source Type: research