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Drug: Tamoxifen
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Total 2054 results found since Jan 2013.
Adherence to oral endocrine therapy in racial/ethnic minority patients with low socioeconomic status before and during the COVID-19 pandemic
CONCLUSION: OET adherence was significantly reduced during the COVID-19 pandemic in racial/ethnic minority patients with low SES. Patient-centered interventions are necessary to improve OET adherence in these patients.PMID:37380914 | DOI:10.1007/s11096-023-01609-6
Source: Clinical Genitourinary Cancer - June 28, 2023 Category: Cancer & Oncology Authors: Sama Rahimi Onyebuchi Ononogbu Anjana Mohan Daniel Moussa Susan Abughosh Meghana V Trivedi Source Type: research
A review of tamoxifen administration regimen optimization for Cre/loxp system in mouse bone study
This study will help researchers in designing gene knockout experiments in bone when using tamoxifen.PMID:37379643 | DOI:10.1016/j.biopha.2023.115045
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 28, 2023 Category: Drugs & Pharmacology Authors: Ming-Yang Chen Fu-Lin Zhao Wen-Lin Chu Ming-Ru Bai De-Mao Zhang Source Type: research
Adherence to oral endocrine therapy in racial/ethnic minority patients with low socioeconomic status before and during the COVID-19 pandemic
CONCLUSION: OET adherence was significantly reduced during the COVID-19 pandemic in racial/ethnic minority patients with low SES. Patient-centered interventions are necessary to improve OET adherence in these patients.PMID:37380914 | DOI:10.1007/s11096-023-01609-6
Source: Clinical Breast Cancer - June 28, 2023 Category: Cancer & Oncology Authors: Sama Rahimi Onyebuchi Ononogbu Anjana Mohan Daniel Moussa Susan Abughosh Meghana V Trivedi Source Type: research
A review of tamoxifen administration regimen optimization for Cre/loxp system in mouse bone study
This study will help researchers in designing gene knockout experiments in bone when using tamoxifen.PMID:37379643 | DOI:10.1016/j.biopha.2023.115045
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 28, 2023 Category: Drugs & Pharmacology Authors: Ming-Yang Chen Fu-Lin Zhao Wen-Lin Chu Ming-Ru Bai De-Mao Zhang Source Type: research
Spatiotemporal control of genome engineering in cone photoreceptors
CONCLUSIONS: The Arr3P2ACreERT2 mouse, an inducible cone-specific Cre driver, is a valuable line in studying cone cell biology, function, as well as its relationship with rod and other retinal cells. Moreover, the Cre activity can be induced by delivering tamoxifen intragastrically as early as PD2, which will be useful for studying retinal development or in rapid degenerative mouse models.PMID:37381060 | DOI:10.1186/s13578-023-01033-3
Source: Cancer Control - June 28, 2023 Category: Cancer & Oncology Authors: Nan-Kai Wang Pei-Kang Liu Yang Kong Yun-Ju Tseng Laura A Jenny Nicholas D Nolan Nelson Chen Hung-Hsi Wang Chun Wei Hsu Wan-Chun Huang Janet R Sparrow Chyuan-Sheng Lin Stephen H Tsang Source Type: research
Adherence to oral endocrine therapy in racial/ethnic minority patients with low socioeconomic status before and during the COVID-19 pandemic
CONCLUSION: OET adherence was significantly reduced during the COVID-19 pandemic in racial/ethnic minority patients with low SES. Patient-centered interventions are necessary to improve OET adherence in these patients.PMID:37380914 | DOI:10.1007/s11096-023-01609-6
Source: Clinical Breast Cancer - June 28, 2023 Category: Cancer & Oncology Authors: Sama Rahimi Onyebuchi Ononogbu Anjana Mohan Daniel Moussa Susan Abughosh Meghana V Trivedi Source Type: research
Carcinogenic roles of MAFG-AS1 in human cancers
This study systematically presents the functions of MAFG-AS1 in various cancers, as well as the findings of bioinformatics analyses of the MAFG-AS1, which should give clear advice for future research.PMID:37351806 | DOI:10.1007/s12094-023-03246-x
Source: Clinical Genitourinary Cancer - June 23, 2023 Category: Cancer & Oncology Authors: Mohsen Ahmadi Firouzeh Morshedzadeh Sayyed Mohammad Hossein Ghaderian Pegah Mousavi Leila Habibipour Maryam Peymani Mohammad Reza Abbaszadegan Soudeh Ghafouri-Fard Source Type: research
NO-sensitive guanylyl cyclase discriminates pericyte-derived interstitial from intra-alveolar myofibroblasts in murine pulmonary fibrosis
CONCLUSION: In summary, αSMA/PDGFRβ-positive myofibroblasts should not be addressed as a homogeneous target cell type within pulmonary fibrosis.PMID:37349733 | DOI:10.1186/s12931-023-02479-2
Source: Cell Research - June 22, 2023 Category: Cytology Authors: Annemarie Aue Nils Englert Leon Harrer Fabian Schwiering Annika Gaab Peter K önig Ralf Adams Achim Schmidtko Andreas Friebe Dieter Groneberg Source Type: research
Effects of 7-ketocholesterol on tamoxifen efficacy in breast carcinoma cell line models in vitro
This study shows that 7-KC can modulate tamoxifen efficacy as well as cellular migration and invasion, making 7-KC a promising candidate for future studies.PMID:37343688 | DOI:10.1016/j.jsbmb.2023.106354
Source: Mol Biol Cell - June 21, 2023 Category: Molecular Biology Authors: Alzbeta Spalenkova Marie Ehrlichova Shouzou Wei F Peter Guengerich Pavel Soucek Source Type: research
Pharmacogenetics and Pharmacokinetics of Tamoxifen in a Zimbabwean breast cancer cohort
This study aimed to determine the association between the CYP2D6 polymorphisms and endoxifen plasma concentrations in a cohort of Zimbabwean breast cancer patients (n = 40). TaqMan genotyping and copy number assays were done to determine CYP2D6 genotypes. Tamoxifen and metabolites were quantitated using LC-MS/MS. The population had high frequencies of the CYP2D6 reduced function alleles, *17 (15%) and *29 (18%). The median endoxifen concentration was 4.78 ng/ml and 55% of the patients, mostly intermediate metabolizers were below the endoxifen therapeutic threshold 5.97 ng/ml. The CYP2D6 phenotypes and activity scores were ...
Source: Clinical Genitourinary Cancer - June 20, 2023 Category: Cancer & Oncology Authors: Bianza Tinotenda Mbavha Roslyn Stella Thelingwani Zedias Chikwambi Anna Mary Nyakabau Collen Masimirembwa Consortium for Genomics and Therapeutics in Africa Source Type: research
