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Drug: Tamoxifen
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Total 2054 results found since Jan 2013.
Pharmacokinetics, safety and preliminary pharmacodynamic evaluation of DARE-VVA1: a soft gelatin capsule containing tamoxifen for the treatment of vulvovaginal atrophy
CONCLUSIONS: DARE-VVA1 is safe and results in minimal systemic exposure to tamoxifen. Preliminary efficacy data support further development of this product.PMID:37288962 | DOI:10.1080/13697137.2023.2211763
Source: Climacteric - June 8, 2023 Category: Geriatrics Authors: A Thurman L Hull B Stuckey J Hatheway C Mauck N Zack D Friend Source Type: research
The G-protein-coupled estrogen receptor, a gene co-expressed with ER α in breast tumors, is regulated by estrogen-ERα signalling in ERα positive breast cancer cells
In conclusion, GPER is positively associated with ERα in breast tumors, and induced by estrogen-ERα signalling axis. Estrogen-mediated induction of GPER makes the cells more responsive to GPER ligands. More in-depth studies are warranted to establish the significance of GPER-ERα co-expression, and their interplay in breast tumor development, progression, and treatment.PMID:37279863 | DOI:10.1016/j.gene.2023.147548
Source: Gene - June 6, 2023 Category: Genetics & Stem Cells Authors: Uttariya Pal Mohan C Manjegowda Neha Singh Snigdha Saikia Betty S Philip Deep Jyoti Kalita Avdhesh Kumar Rai Anupam Sarma Vandana Raphael Deepak Modi Amal Chandra Kataki Anil Mukund Limaye Source Type: research
Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research
Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research
Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research
Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research
Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research
Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research
Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research
Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research
Lysine crotonylation of SERCA2a correlates to cardiac dysfunction and arrhythmia in Sirt1 cardiac-specific knockout mice
Int J Biol Macromol. 2023 Jun 1:125151. doi: 10.1016/j.ijbiomac.2023.125151. Online ahead of print.ABSTRACTProtein post-translational modifications (PTMs) are important regulators of protein functions and produce proteome complexity. SIRT1 has NAD+-dependent deacylation of acyl-lysine residues. The present study aimed to explore the correlation between lysine crotonylation (Kcr) on cardiac function and rhythm in Sirt1 cardiac-specific knockout (ScKO) mice and related mechanism. Quantitative proteomics and bioinformatic analysis of Kcr were performed in the heart tissue of ScKO mice established with a tamoxifen-inducible Cr...
Source: International Journal of Biological Macromolecules - June 3, 2023 Category: Biochemistry Authors: Huan-Xin Chen Xiang-Chong Wang Hai-Tao Hou Jun Wang Qin Yang Yuan-Lu Chen Hou-Zao Chen Guo-Wei He Source Type: research
Identification of potential benzoxazolinone as CYP1B1 inhibitors via molecular docking, dynamics, waterswap, and In vitro analysis
New J. Chem., 2023, Accepted Manuscript DOI: 10.1039/D3NJ01138K, PaperBaddipadige Raju, Himanshu Verma, Gera Narendra, Gurleen Kaur Tung, Subheet Kumar Jain, Om Silakari Overexpression of Cytochrome P450 1B1 in malignancies is accountable for the biotransformation-based inactivation of various chemotherapeutics such as docetaxel, paclitaxel, cisplatin, and tamoxifen. Additionally, it also plays a major role... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - May 31, 2023 Category: Chemistry Authors: Baddipadige Raju Source Type: research
