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Drug: Tamoxifen
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Total 2054 results found since Jan 2013.
Is venous thromboembolism a time-dependent event in breast cancer patients taking tamoxifen?
Breast Cancer. 2023 May 4. doi: 10.1007/s12282-023-01464-3. Online ahead of print.NO ABSTRACTPMID:37142897 | DOI:10.1007/s12282-023-01464-3
Source: Breast Cancer - May 4, 2023 Category: Cancer & Oncology Authors: Kadri Altundag Source Type: research
Endocrine Therapy for Primary and Secondary Prevention After Diagnosis of High-Risk Breast Lesions or Preinvasive Breast Cancer
J Clin Oncol. 2023 May 1:JCO2300455. doi: 10.1200/JCO.23.00455. Online ahead of print.ABSTRACTThe Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice.Patients with high...
Source: Clinical Genitourinary Cancer - May 1, 2023 Category: Cancer & Oncology Authors: Alison Laws Rinaa S Punglia Source Type: research
Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters
Biomaterials. 2023 Apr 21;298:122128. doi: 10.1016/j.biomaterials.2023.122128. Online ahead of print.ABSTRACTMulticellular clustering provides cancer cells with survival advantages and facilitates metastasis. At the tumor migration front, cancer cell clusters are surrounded by an aligned stromal topography. It remains unknown whether aligned stromal topography regulates the resistance of migrating cancer cell clusters to therapeutics. Using a hybrid nanopatterned model to characterize breast cancer cell clusters at the migration front with aligned stromal topography, we demonstrate that topography-induced migrating cancer ...
Source: Biomaterials - April 30, 2023 Category: Materials Science Authors: Chia-Yi Su Alex Wu Zhipeng Dong Chris P Miller Allister Suarez Andrew J Ewald Eun Hyun Ahn Deok-Ho Kim Source Type: research
Modeling and simulation of bone cells dynamic behavior under the late effect of breast cancer treatments
Med Eng Phys. 2023 May;115:103982. doi: 10.1016/j.medengphy.2023.103982. Epub 2023 Apr 20.ABSTRACTBreast Cancer (BC) treatments have been proven to interfere with the health of bones. Chemotherapy and endocrinal treatment regimens such as tamoxifen and aromatase inhibitors are frequently prescribed for women with BC. However, these drugs increase bone resorption and reduce the Bone Mineral Density (BMD), thus increasing the risk of bone fracture. In the current study, a mechanobiological bone remodeling model has been developed by coupling cellular activities, mechanical stimuli, and the effect of breast cancer treatments ...
Source: Health Physics - April 29, 2023 Category: Physics Authors: Imane Ait Oumghar Abdelwahed Barkaoui Abdellatif El Ghazi Patrick Chabrand Source Type: research
Postoperative Adjuvant Anastrozole for 10 or 5 Years in Patients With Hormone Receptor-Positive Breast Cancer: AERAS, a Randomized Multicenter Open-Label Phase III Trial
CONCLUSION: Continuing adjuvant anastrozole for an additional 5 years after 5 years of initial treatment with anastrozole or tamoxifen followed by anastrozole was well tolerated and improved DFS. Although no difference in overall survival was observed as in other trials, extended anastrozole therapy could be one treatment choice in postmenopausal patients with hormone receptor-positive breast cancer.PMID:37079878 | DOI:10.1200/JCO.22.00577
Source: Clinical Breast Cancer - April 20, 2023 Category: Cancer & Oncology Authors: Takuji Iwase Shigehira Saji Kotaro Iijima Kenji Higaki Shoichiro Ohtani Yasuyuki Sato Yasuo Hozumi Yoshie Hasegawa Yasuhiro Yanagita Hiroyuki Takei Maki Tanaka Hideji Masuoka Masahiko Tanabe Chiyomi Egawa Yoshifumi Komoike Toshitaka Nakamura Hiroshi Ohtsu Source Type: research
