This page shows you the latest news items in this category. This is page number 19.

Total 4937 results found since Jan 2013.

Sarcoidosis and neoplasm, a coincidence?
Conclusion: the presence of TNF-α-863 A allele was associated with higher risk of sarcoidosis malignancies syndrome in our small group of patients. This finding needs verification in a large cohort of sarcoidosis patients.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Goljan Geremek, A., Czystowska, M., Skoczylas, A., Demkow, U., Puscinska, E., Bednarek, M., Nowinski, A., Sliwinski, P. Tags: Diffuse Parenchymal Lung Disease Source Type: research

The granulomas morphology and clinical picture of sarcoidosis
Conclusion: The severity of pulmonary dissemination in sarcoidosis is directly proportional to the number of cellular elements of the granuloma, except for macrophages. Symptoms of the disease are caused by features of the granulomas structure.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Denisova, O., Palchikova, I., Purlik, I., Chernjavskaya, G., Chernogoryuk, G. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Echocardiographic parameters in suspected cardiac sarcoidosis patients-the role of speckle tracking strain analysis in the diagnosis of cardiac sarcoidosis
Conclusion: In a cohort of suspected CS patients GCS may provide significant diagnostic information and guide advanced imaging for CS.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Kouranos, V., Minz, M., Danylenko, O., Baksi, J., Wechalekar, K., Kokosi, M., Sharma, R., Wells, A., Senior, R., Khattar, R., Cowie, M. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Human chitotriosidase analysis: a reliable biomarker of sarcoidosis severity
Conclusion: CTO is a non-invasive, reproducible and useful biomarker in the clinical practice; high CTO activity may predict extrapulmonary involvement of disease and could be useful to identify patients requiring pharmacological treatments.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Cameli, P., Bargagli, E., Bennett, D., Bianchi, N., Refini, R. M., Rottoli, P., Cillis, G. Tags: Diffuse Parenchymal Lung Disease Source Type: research

The role of 18-FDG PET/CT in lung sarcoidosis
Conclusion: 18F-FDG PET/CT evaluates the extent and inflammatory activity of lung sarcoidosis and was observed in 79% of patients and associated with functional and clinical parameters.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Pavlovic-Popovic, Z., Vukoja, M., Mihailovic, J., Prvulovic Bunovic, N., Lucic, S. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Functional and symptomatic burden of small fiber neuropathy in sarcoidosis
Sarcoidosis is frequently complicated by loss of unmyelinated small nerve fibers, leading to pain and dysautonomia. The implications of sarcoidosis–associated small fiber neuropathy (SFN) on quality of life and functional status are not well described. We systematically measured medication burden, pain (Brief Pain Inventory), fatigue, quality of life (SF-36) and 6 minute walk distance (6MWD) at baseline in a prospective study of 64 US and Dutch sarcoidosis patients. All patients had SFN confirmed by skin biopsy or corneal confocal microscopy. We assessed neuropathic symptoms using the Neuropathic Pain Symptom Invento...
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Culver, D., Bjournas, D., Dahan, A., Brines, M. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Interleukin-2 and C-reactive protein in assessing the effectiveness of pulmonary sarcoidosis treatment
Conclusions: Identifying patterns of these disorders at the molecular level intercellular interaction in pulmonary sarcoidosis enables to determine the effectiveness and adequacy of prescribed therapy, by patient-specific assessment of the inflammatory process activity.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Ostrovskyy, M., Shvets, K., Ostrovska, K., Savelikhina, I., Kulynych-Miskiv, M., Varunkiv, O. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Evaluation of Impulse Oscillometry in patients with SarcoidosisEvaluation of Impulse Oscillometry system in patients with pulmonary Sarcoidosis
Conclusion: Characteristic changes in IOS indices were found in patients with Sarcoidosis. R5 may help be useful in detecting early manifestations of airflow limitation in pulmonary sarcoidosis patients.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Talwar, A., Akhtar, N., Sampath, M., Bade, G., Trivedi, A., Guleria, R. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Screening of?ardiac involvement in sarcoidosis
Conclusion: The developed method of screening can be used for the selection of patients who require further assessment to exclude cardiac involvement.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Zhurkin, D., Baradzina, H., Syty, V. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Development of a multivariate model to predict clinical deterioration in pulmonary sarcoidosis
Conclusions: We believe this is the first study to demonstrate the prognostic value of ALP and albumin in predicting decline in pulmonary sarcoidosis. Interestingly, MRC breathlessness score outperformed baseline DLCO in this model. We plan to remove confounders such as treatment and validate our model in a second cohort of patients presenting to a separate clinic. Further validation of this model may assist in decisions of when to initiate treatment.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Yung, H., Thillai, M., Fiddler, C., Simler, N., Chilvers, E., Parfrey, H. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Noninvasive Arterial Stiffness Measurement in Patients with Sarcoidosis
Conclusions: Opposed the previous study, we could not demonstrate arterial wall impairement in sarcoidosis patients compared to controls. The patient population was heterogonous concerning disease duration and the sample size, especially in control group was relatively small.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Demirdogen Cetinoglu, E., Uysal, A., Aydin Guclu, O., Ozkaya, G., Uzaslan, E., Karadag, M., Serdar, O. A. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Gene variants and clinical course of pulmonary sarcoidosis in a Slavic population
Conclusions: Our data confirm MHC-related SNPs (TNFA, HLA) and nominate further variants as plausible prognostic markers for resolution/progression of sarcoidosis, respectively among West Slavs. Further investigations should be performed in other ethnicities and include additional clinical information such as chest X-ray stage and/or treatment requirement/response.Grant: IGA_PU_LF_2016_009/2017_014 and LO1304.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Kishore, A., Sikorova, K., Doubkova, M., Rebała, K., Dubaniewicz, A., Kolek, V., Petrek, M. Tags: Genes and Environment Source Type: research

Insights from RNA-sequencing of bronchoalveolar lavage cells in a large sarcoidosis cohort
Conclusion: RNA-sequencing of BAL in sarcoidosis patients identified novel genes associated with features of disease. Preliminary analysis suggests the presence of molecular disease endotypes.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Vukmirovic, M., Yan, X., Gibson, K. F., Gulati, M., DeIuliis, G., Woolard, T., Adams, T., Hu, B., Zang, W., Mihaljinec, A., Luijk, H. D., Aurelien, N., O'Neal, S. M., Becich, M. J., Hochheiser, H., Herzog, E. L., Senior, R. M., Chen, E. S., Morris, A. M., Tags: Molecular Pathology and Functional Genomics Source Type: research

The possible role of Stomoxys calcitrans in equine sarcoid transmission
This study aimed to investigate whether BPV-negative stable flies (Stomoxys calcitrans) become positive for BPV DNA after exposure to equine sarcoid or bovine papilloma tissue under experimental conditions and, if so, for how long. A total of 420 stable flies were caught alive and exposed to BPV positive equine sarcoid or bovine papilloma tissue. During the following week, dead flies were collected daily and BPV loads were determined by quantitative PCR. There was a significant rise in BPV load after tissue exposure both in sarcoid and papilloma exposed flies, but the viral load was higher and remained high for a longer ti...
Source: The Veterinary Journal - December 6, 2017 Category: Veterinary Research Source Type: research

Muscle strength training; does number of repetitions affect fatigue in sarcoidosis patients?
Conclusion: Many repetitions increase fatigue significantly from baseline to end exercise and remains after 24 hours. However, muscle strength training in patients with sarcoidosis induce only a slight change in fatigue, both after 5RM and 25RM.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Grongstad, A., Kopke Vollestad, N., Oldervoll, L., Spruit, M., Edvardsen, A. Tags: Physiotherapists Source Type: research

Comparing outcomes internationally in pulmonary sarcoidosis: PFT change by scadding stage
Conclusions: In our multicenter cohort we detected differences in baseline FVC %predicted between Scadding stages. Remarkably, both FVC, FEV1 and DLCOc improvement was established in all stages.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Kampstra, N., van der Wees, P. J., van der Nat, P. B., van Beek, F., van Moorsel, C. H., Baughman, R. P., Culver, D. C., Renzoni, E. A., Kouranos, V., Wuyts, W., Wijsenbeek, M. S., Zanen, P., Grutters, J. C. Tags: Epidemiology Source Type: research

Sarcoidosis in Israel: Clinical outcome status, organ involvement and long term follow up
This study reviewed the clinical outcome status (COS) and organ involvement of Israeli sarcoidosis patients during a five year period. Then, we compared our results to the WASOG COS and the ACCESS instruments in order to evaluate their relevance to the Israeli population.Methods: The retrospective study group consisted of 166 patients from 2010 to 2015. All patients with clinical presentation of sarcoidosis were included. Data on demographic characteristics, presenting symptoms, co-morbidities, disease duration, lung function tests, treatment program, chest X-ray and chest high resolution computed tomography (HRCT) were co...
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Markavych, N., Epstein Shochet, G., Shitrit, D., Israeli-Shani, L. Tags: Epidemiology Source Type: research

Sarcoidosis in South Croatia, 30-year follow up
Conclusion: The incidence in the wider district of Split-Dalmatian county is low (3.1-3.4), the most common form is the stage II endothoracal sarcoidosis. Patients live a number of years without any significant complications. Mortality is low, 1.56%, which is directly associated with S.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Skopljanac, I., Mise, K., Segrt, I., Ilak, D. Tags: Epidemiology Source Type: research

Changes in anxiety and depression after pulmonary rehabilitation in distressed patients with sarcoidosis in ProKaSaRe
Conclusion: Multidisciplinary PR seems to have a long lasting positive effect on psychological distress in patients with sarcoidosis even one year after PR.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Nowik, D., Schultz, K., Buhr-Schinner, H., Heitmann, R., Hummel, S., Tönnesmann, U., van der Meyden, J., Lingner, H. Tags: Rehabilitation and Chronic Care Source Type: research

Epidemiology of sarcoidosis in the Leningrad region of Russia
Conclusion: The increasing incidence and prevalence of PS in the last years can be explained by new management of PS patients in Russia and the use modern methods of examination and treatment.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Baranova, O. P., Ermolova, S. O., Speranskaya, A. Tags: Clinical Problems Others Source Type: research

68 Gallium DOTA-NOC PET/CT as a predictor of disease activity in sarcoidosis
Conclusion: 68Ga-DOTA-NOC PET/CT emerged as a useful tool to detect clinical activity, treatment response in sarcoidosis patients with thoracic involvement.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Singh, A., Sharma, S., Tripathi, M., Mian, A., Sharma, S. K. Tags: Imaging Source Type: research

Transcriptional Survey of Alveolar Macrophages in a Murine Model of Chronic Granulomatous Inflammation Reveals Common Themes with Human Sarcoidosis.
In conclusion, an integrated network and transcriptomics approach revealed substantial functional similarities between a murine model and human sarcoidosis particularly with respect to activation of immune-specific pathways. PMID: 29212802 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - December 6, 2017 Category: Cytology Authors: Mohan A, Malur A, McPeek M, Barna BP, Schnapp LM, Thomassen MJ, Gharib SA Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Clinico-radiological diagnosis of atypical forms of pulmonary sarcoidosis
Conclusions: Accumulation of experience in clinical-radiological examination of patients with PS requires a revision of the existing classification and addition of atypical forms of PS that are difficult to diagnose, require adjustment of the diagnostic algorithm, and development of new approaches to treatment.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Baranova, O. P., Speranskaya, A., Vasilieva, M. Tags: Imaging Source Type: research

Late Breaking Abstract - Promising results of the infliximab biosimilar Inflectra(R) in severe sarcoidosis patients
Conclusion: The infliximab biosimilar Inflectra® seems well tolerated and effective in the treatment of refractory sarcoidosis.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Schimmelpennink, M. C., Vorselaars, A. D. M., Van Beek, F. T., Crommelin, H. C., Keijsers, R. G. M., Veltkamp, M. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Expression of mRNA of selected inflammatory markers in BALf cells from patients with sarcoidosis and idiopathic pulmonary fibrosis (IPF)
Conclusions: the inflammatory and immune pathways in sarcoidosis and IPF show some similarities. However, the clinical implication of the expression of inflammatory markers is different in both diseases.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Maskey-Warzechowska, M., Paplinska-Goryca, M., Witkowska, A., Nejman-Gryz, P., Korczynski, P., Krenke, R. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Safety of corticosteroid therapy in patients with pulmonary sarcoidosis
Conclusion: The need of alternative immunosuppressive therapy in sarcoidosis patients with lung parenchymal lesions is about 32,4 %. The study data indicate the necessity of development of new effective and safe immunosuppressive therapy in pulmonary sarcoidosis patients.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Merenkova, I., Dziublyk, Y. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Malondialdehyde and nitrotyrosine as markers of peroxynitrite activity in sarcoidosis
Sarcoidosis (SA) is granulomatous disease with unknown etiology. Infectious factors, genetics and autoimmunity are considered in the etiopathogenesis of SA. In contrast to tuberculosis (TB), we evidenced decreased clearance of immune complexes with mycobacterial heat shock proteins by resistant to apoptosis monocytes with diminished serum microbicidal/degradable nitrate/nitrite and increased concentration of peroxynitrite (ONOO-) in SA. ONOO- reacts with a variety of lipids and proteins initiating peroxidation process with subsequent oxidative tissue injury. Malondialdehyde (MDA) and nitrotyrosine (NT) are the final produc...
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Dubaniewicz, A., Skotarczak, M., Romanowicz, G., Słominski, J. M., Kalinowski, L. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Outcome predictive factors in patients with sarcoidosis
Conclusions: Skin and eye disease, SaO2<95%, FEV1<60% and HRCT score ≥8 in sarcoidosis patients are risk factors for a chronic disease. Erythema nodosum is a clinical sign associated with a favorable outcome of sarcoidosis. Discontinuation of CS earlier than 11 months is associated with an increased risk for relapse.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Calaras, D., Munteanu, O., Luchian, Z., David, A., Botnaru, V. Tags: Diffuse Parenchymal Lung Disease Source Type: research

In situ analysis by SEM-EDX spectroscopy of 10 sarcoidosis cases from MINASARC study
We report the results obtained by MA-SEM from 10 sarcoidosis cases.Objectives: To compare the results of MA-SEM and MA-TEM.Methods: 5 mediastinal lymph nodes obtained by endobronchial ultrasound trans-bronchial needle aspiration (EBUS/TBNA) and 5 bronchial biopsies (BB) were studied by SEM-EDX.Results: * + to ++++: level of particles loadDiscussion and conclusion: MA-SEM on tissue sections is feasible and may give potential interesting results. In one manicurist (n°4), it identified silica particles in the lymph node and a high level in BAL. In a fire safety worker (n°10), it identified steel particles associated t...
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Catinon, M., Chemarin, C., Thivolet, F., Kambouchner, M., Bernaudin, J.-F., Cavalin, C., Sfarghiu, A.-M., Arbib, F., Freynet, O., Freymond, N., Mornex, J.-F., Rosental, P.-A., Vincent, M., Valeyre, D., Pison, C. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Neurological signs in patients with sarcoidosis - is it neurosarcoidosis?
Conclusions: Neurological symptoms in patients with pulmonary sarcoidosis are rare and in most cases are assessed as unrelated to neurosarcoidosis.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Kempisty, A., Blasinska-Przerwa, K., Marcinkowska, E., Kus, J. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Fatigue perception and related factors in patients with advanced sarcoidosis and COPD patients
Conclusion: We believe that while the fatigue severity which was found higher in COPD patients was affected by lower pulmonary functions and poor quality of life, in sarcoidosis patients fatigue symptom along with the dyspnea limits the exercise capacity of patients and affects the quality of life negatively.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Ozalevli, S., Naz, I., Bayraktar, D., Dogan Sahin, H. Tags: Diffuse Parenchymal Lung Disease Source Type: research

The role of HLA-DRB1* alleles in prediction of long term prognosis in sarcoidosis
Discussion: HLA-DRB1*14 alleles could predict long term resolution in sarcoidosis and early prediction of long term resolution could improve prognosis.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Özyilmaz, E., Durmaz, A., Guzelbaba, B., Hasan, O. O., Goruroglu Ozturk, O., Kuleci, S., Hanta, I., Erken, E., Kocabas, A. Tags: Diffuse Parenchymal Lung Disease Source Type: research

The frequency of etarnecept related sarcoidosis
Discussion: Etanercept related sarcoidosis is a rare condition with good prognosis.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Özyilmaz, E., Guzelbaba, B., Durmaz, A., Orhan, G., Sarar, G., Gokcen, N., Ozbek, S., Erken, E. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Posaconazole in vitro action on peripheral blood mononuclear cells from sarcoidosis patients
Antifungal medication (AFM) was efficient in many, albeit not all, sarcoidosis. Insoluble β-glucan (BGP) was found in BALF, in lymph nodes and induces the production of several cytokines from peripheral blood mononuclear cells (PBMC) in vitro. We set two hypotheses:Posaconazole (PSC) decreases the secretion of cytokines after stimulation with BGP and PSC acts on BGP anddecreases its capacity to induce cytokine production. PBMCs from sarcoidosis (n=6) and healthy (n=5) were stimulated for 4h with BGP after 24h preincubation with PSC, with methylprednisolone or with medium alone. To study the interaction between BGP and...
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Stopinsek, S., Salobir, B., Ihan, A., Simcic, S., Tercelj-Zorman, M. Tags: Diffuse Parenchymal Lung Disease Source Type: research

Urinary 8-Hydroxy-2'-Deoxyguanosine as a Myocardial Oxidative Stress Marker Is Associated With Ventricular Tachycardia in Patients With Active Cardiac Sarcoidosis Cardiomyopathies
Conclusions— U-8-OHdG levels are associated with VT in patients with active CS diagnosed by 18F-flurodeoxyglucose positron-emission tomography, providing additive and relevant information about the arrhythmia substrate.
Source: Circulation: Cardiovascular Imaging - December 5, 2017 Category: Radiology Authors: Ishiguchi, H., Kobayashi, S., Myoren, T., Kohno, M., Nanno, T., Murakami, W., Oda, S., Oishi, K., Okuda, S., Okada, M., Suga, K., Yano, M. Tags: Cardiomyopathy, Heart Failure, Nuclear Cardiology and PET Cardiomyopathies Source Type: research

Complementary Role of CMR to Conventional Screening in the Diagnosis and Prognosis of Cardiac Sarcoidosis
Conclusions Of all cardiac tests, CMR was the most valuable in the diagnosis and prognosis of cardiac sarcoidosis in a general sarcoidosis population. Echocardiography had an overall limited diagnostic value as a screening test, and an abnormal study, despite a high positive predictive value, may still need confirmation with CMR.
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - December 4, 2017 Category: Radiology Authors: Kouranos, V., Tzelepis, G. E., Rapti, A., Mavrogeni, S., Aggeli, K., Douskou, M., Prasad, S., Koulouris, N., Sfikakis, P., Wells, A., Gialafos, E. Tags: Original Research Source Type: research

Radiological and nuclear medicine imaging of sarcoidosis.
Authors: Larici AR, Glaudemans AW, Del Ciello A, Slart RH, Calandriello L, Gheysens O Abstract Sarcoidosis is a multisystem chronic inflammatory disease of unknown etiology characterized by widespread growth of non-caseating granulomas. The diagnosis of sarcoidosis is based on clinical and imaging presentation, histologic confirmation and the absence of alternative diseases. Radiology and Nuclear Medicine play an essential role in the diagnostic work-up of patients with sarcoidosis to assess disease extent and activity. In addition, imaging modalities have shown their potential in managing these patients in terms o...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - December 3, 2017 Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research

Severe infections in sarcoidosis: Incidence, predictors and long-term outcome in a cohort of 585 patients
Abstract Sarcoidosis is associated with cell-mediated immunodeficiency and treatment of symptomatic sarcoidosis usually includes systemic immunosuppressants. Data relative to incidence, prognosis factors, and outcome of infections are scarce. Retrospective cohort study of 585 patients with biopsy proven sarcoidosis in a tertiary referral specialist clinic, with a nested case-control analysis. Twenty nine patients (4.9%) with severe infections were compared to 116 controls subjects with sarcoidosis, matched according to their gender, ethnicity, age at diagnosis, and treatment with corticosteroids. After a median follow-...
Source: Medicine - December 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

GSE100500 Transcriptional Survey of Alveolar Macrophages in a Murine Model of Chronic Granulomatous Inflammation Reveals Common Themes with Human Sarcoidosis
Conclusions: Our MWCNT murine model has an alveolar macrophage signature that varies significantly from control mice. Application of an unbiased transcriptomic approach revealed substantial functional similarities between a murine MWCNT model and human sarcoidosis particularly with respect to activation of immune-specific pathways.
Source: GEO: Gene Expression Omnibus - December 1, 2017 Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research

Acute orbital sarcoidosis with preceding fever and erythema nodosum.
PMID: 29217052 [PubMed - in process]
Source: Canadian Journal of Ophthalmology - December 1, 2017 Category: Opthalmology Authors: Simpson SM, Farmer J, Kratky V Tags: Can J Ophthalmol Source Type: research

PET MRI Study in Patients With Cardiac Sarcoidosis
Conditions:   Inflammatory Cardiomyopathy;   Sarcoidosis Intervention:   Diagnostic Test: simultaneous combined 18F-FDG PET and cardiac MRI imaging Sponsor:   University Health Network, Toronto Recruiting
Source: ClinicalTrials.gov - November 29, 2017 Category: Research Source Type: clinical trials