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Total 5152 results found since Jan 2013.

Intravascular lymphoma forming massive aortic tumors complicated with sarcoidosis and focal segmental glomerulosclerosis: a case report and literature review
Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of extranodal diffuse large B-cell lymphoma characterized by proliferation of B cells within small vessels. Herein, we report a case of a 77-year-...
Source: BMC Nephrology - October 29, 2018 Category: Urology & Nephrology Authors: Yasuhiro Oda, Kunihiro Ishioka, Takayasu Ohtake, Shuku Sato, Yotaro Tamai, Rikako Oki, Kenji Matsui, Yasuhiro Mochida, Hidekazu Moriya, Sumi Hidaka and Shuzo Kobayashi Tags: Case report Source Type: research

Update on Vertigo in Autoimmune Disorders, from Diagnosis to Treatment.
Authors: Girasoli L, Cazzador D, Padoan R, Nardello E, Felicetti M, Zanoletti E, Schiavon F, Bovo R Abstract The prevalence of autoimmune diseases has been increasing over the last 20 years. The clinical presentation of this large and heterogeneous group of disorders depends on whether the involvement is organ-specific or non-organ-specific. Dizziness, vertigo, and disequilibrium are common symptoms reported by patients with vestibulocochlear involvement. The association of vertigo and autoimmune diseases has been largely documented, suggesting that autoimmune disorders could be overrepresented in patients with ver...
Source: Journal of Immunology Research - October 26, 2018 Category: Allergy & Immunology Tags: J Immunol Res Source Type: research

Utility of routine chest radiography in ocular tuberculosis and sarcoidosis
Source: International Journal of Tuberculosis and Lung Disease - October 26, 2018 Category: Respiratory Medicine Authors: Shaw, J. A. Smit, D. P. Griffith-Richards, S. Koegelenberg, C. F. N. Tags: ORIGINAL ARTICLES - Tuberculosis Source Type: research

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We thank Drs. Valentin, Hyde, Gomez and Patel for commenting on our recently published article “Sarcoidosis and IPF in the same patient-a coincidence, an association or a phenotype?” [1]. Indeed, one of our objectives in reporting our observations was to provoke further interest in the scientific community regarding such patients and conduct of clinical studies in such cohorts.
Source: Respiratory Medicine - October 26, 2018 Category: Respiratory Medicine Authors: Bridget F. Collins, Ganesh Raghu Tags: Correspondence Source Type: research

Neurosarcoidosis Presenting Initially as Idiopathic Vocal Cord Paralysis.
CONCLUSIONS:: Neurosarcoidosis is not usually considered in the differential diagnosis of vocal cord paralysis. At initial presentation, all patients lacked other cranial neuropathies and systemic sarcoidosis manifestations, making diagnosis difficult. Otolaryngologists should be aware of this rare presentation, as prompt diagnosis by brain magnetic resonance imaging with or without central nervous system biopsy, as opposed to traditional chest radiography or computed tomography for the workup of peripheral nerve injury, is necessary. Serial laryngeal examinations are recommended for close monitoring of progressive disease...
Source: The Annals of Otology, Rhinology, and Laryngology - October 26, 2018 Category: ENT & OMF Authors: Wu TJ, Lewis SM, Woo P Tags: Ann Otol Rhinol Laryngol Source Type: research

Next-Generation Sequencing Based HLA Typing: Deciphering Immunogenetic Aspects of Sarcoidosis
Amit Kishore, Martin Petrek
Source: Frontiers in Genetics - October 25, 2018 Category: Genetics & Stem Cells Source Type: research

Pulmonary follicular lymphoma showing diffuse micronodules mimicking sarcoidosis.
Authors: Takuma K, Eri H, Satoshi I, Takashi O PMID: 30333400 [PubMed - as supplied by publisher]
Source: Internal Medicine - October 20, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Effect of Cardiac Resynchronization Therapy on Left Ventricular Remodeling in Patients with Cardiac Sarcoidosis
Cardiac resynchronization therapy (CRT) has been shown to be beneficial in patients with medically refractory heart failure. While it has been found to be effective in a wide range of etiologies for non-ischemic cardiomyopathy, its role in improving remodeling and survival of patients with cardiac sarcoidosis (CS) remains undefined. We performed a retrospective review of all patients at our institution with CS who underwent implantation of a CRT device between 2007 and 2017. The outcomes of this population were compared to the outcomes of a cohort of patients with non-ischemic cardiomyopathy with an etiology other than sarcoidosis.
Source: The American Journal of Cardiology - October 20, 2018 Category: Cardiology Authors: Divyang Patel, Kevin M. Trulock, Saleem Toro, Adam Grimaldi, Matthew Gonzalez, Laurie Ann Moennich, Eiran Z. Gorodeski, Emer Joyce, Mark Niebauer, Bruce L. Wilkoff, Niraj Varma, John W. Rickard Source Type: research

The combination of EBUS-TBNA and the PAB antibody led to a successful treatment for lung cancer in a patient with asymptomatic sarcoidosis mimicking nodal metastasis
Publication date: Available online 18 October 2018Source: Respiratory Medicine Case ReportsAuthor(s): Mari Tone, Nobuyasu Awano, Minoru Inomata, Naoyuki Kuse, Tatsunori Jo, Hanako Yoshimura, Yoshiaki Furuhata, Tamiko Takemura, Toshio Kumasaka, Takehiro IzumoAbstractCorrect staging of lung cancer is important for the selection of the best therapy, but discriminating between lymphadenopathy from lung cancer and from sarcoidosis by imaging examinations is difficult. Additionally, distinguishing lymphadenopathy of sarcoidosis from sarcoid reactions which are sometimes caused by lung cancer is difficult on imaging and pathologi...
Source: Respiratory Medicine Case Reports - October 19, 2018 Category: Respiratory Medicine Source Type: research

Efficacy of Remission-induction Regimen With Infliximab for Severe Extrathoracic Sarcoidosis (EFIRTES)
Condition:   Extrathoracic Sarcoidosis Interventions:   Drug: Infliximab;   Drug: Placebo Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

PET/MR Imaging In Patients With Cardiac Sarcoidosis
Condition:   Cardiac Sarcoidosis Interventions:   Other: 18F-FDG;   Drug: Prednisolone Sponsor:   University of Edinburgh Recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

Efficacy of Remission-induction Regimen With Infliximab for Severe Extrathoracic Sarcoidosis (EFIRTES)
Condition:   Extrathoracic Sarcoidosis Interventions:   Drug: Infliximab;   Drug: Placebo Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

PET/MR Imaging In Patients With Cardiac Sarcoidosis
Condition:   Cardiac Sarcoidosis Interventions:   Other: 18F-FDG;   Drug: Prednisolone Sponsor:   University of Edinburgh Recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

Efficacy of Remission-induction Regimen With Infliximab for Severe Extrathoracic Sarcoidosis (EFIRTES)
Condition:   Extrathoracic Sarcoidosis Interventions:   Drug: Infliximab;   Drug: Placebo Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

PET/MR Imaging In Patients With Cardiac Sarcoidosis
Condition:   Cardiac Sarcoidosis Interventions:   Other: 18F-FDG;   Drug: Prednisolone Sponsor:   University of Edinburgh Recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

Efficacy of Remission-induction Regimen With Infliximab for Severe Extrathoracic Sarcoidosis (EFIRTES)
Condition:   Extrathoracic Sarcoidosis Interventions:   Drug: Infliximab;   Drug: Placebo Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

PET/MR Imaging In Patients With Cardiac Sarcoidosis
Condition:   Cardiac Sarcoidosis Interventions:   Other: 18F-FDG;   Drug: Prednisolone Sponsor:   University of Edinburgh Recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

Efficacy of Remission-induction Regimen With Infliximab for Severe Extrathoracic Sarcoidosis (EFIRTES)
Condition:   Extrathoracic Sarcoidosis Interventions:   Drug: Infliximab;   Drug: Placebo Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

PET/MR Imaging In Patients With Cardiac Sarcoidosis
Condition:   Cardiac Sarcoidosis Interventions:   Other: 18F-FDG;   Drug: Prednisolone Sponsor:   University of Edinburgh Recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

Efficacy of Remission-induction Regimen With Infliximab for Severe Extrathoracic Sarcoidosis (EFIRTES)
Condition:   Extrathoracic Sarcoidosis Interventions:   Drug: Infliximab;   Drug: Placebo Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

PET/MR Imaging In Patients With Cardiac Sarcoidosis
Condition:   Cardiac Sarcoidosis Interventions:   Other: 18F-FDG;   Drug: Prednisolone Sponsor:   University of Edinburgh Recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

Hilar and mediastinal sarcoid-like reaction after the treatment of malignant tumors: imaging features and natural course on 18 F-FDG-PET/CT
ConclusionAfter the treatment of malignancies, benign sarcoid-like reaction was rarely observed during follow-up. Although sarcoid-like reaction appeared a long time after the treatment of malignancies, it frequently and spontaneously regressed in a relatively short period of time.
Source: Japanese Journal of Radiology - October 15, 2018 Category: Radiology Source Type: research

Acute sarcoidosis in a multiple sclerosis patient after alemtuzumab treatment.
CONCLUSION: Our case highlights the profound effect of alemtuzumab on the immune system and its possible risk for autoimmune complications. PMID: 30307371 [PubMed - as supplied by publisher]
Source: Nuklearmedizin - October 11, 2018 Category: Radiology Authors: Graf J, Ringelstein M, Lepka K, Schaller J, Quack H, Hartung HP, Aktas O, Albrecht P Tags: Mult Scler Source Type: research

The natural history of cutaneous sarcoidosis. Clinical spectrum and histological analysis of 40 cases
ConclusionsSarcoidosis may be manifested as an isolated cutaneous disorder. No clinical or histopathological features seem to be helpful to discriminate cases of a persistent isolated cutaneous disease from those that will develop systemic involvement. Since the development of systemic involvement in cases of isolated cutaneous sarcoidosis can occur many years afterward, careful monitoring seems advisable, and a long follow ‐up is recommended.
Source: International Journal of Dermatology - October 10, 2018 Category: Dermatology Authors: Lidia Garc ía‐Colmenero, Julia M. Sánchez‐Schmidt, Carlos Barranco, Ramon M. Pujol Tags: Report Source Type: research

Sarcoidosis: a benign disease or a culture of neglect?
The widespread perception that sarcoidosis is essentially a benign disease has undoubtedly contributed to a lack of investment in sarcoidosis-related public health and research initiatives. Respiratory clinicians managing both pulmonary sarcoidosis and idiopathic pulmonary fibrosis may be especially likely to subscribe to this view. Unlike most other forms of fibrotic lung disease, pulmonary sarcoidosis stabilizes with time, with or without therapy, in the majority of patients. Sarcoidosis patients with major cardiac or neurologic involvement are often managed by sub-specialists and may be under-represented in general sarcoidosis cohorts.
Source: Respiratory Medicine - October 6, 2018 Category: Respiratory Medicine Authors: Athol U. Wells Tags: Editorial Source Type: research

Which is the proper reference tissue for measuring the change in FDG PET metabolic volume of cardiac sarcoidosis before and after steroid therapy?
ConclusionsWe measured FDG uptake in the liver and blood pool before and during steroid therapy. Steroid therapy increased the liver uptake but not the blood pool uptake. Our findings suggested that the DA uptake is a more suitable threshold than liver uptake to evaluate therapeutic effects using volume-based analysis of cardiac FDG PET.
Source: EJNMMI Research - October 5, 2018 Category: Radiology Source Type: research

Micropapular Cutaneous Sarcoidosis Reviewed
Conclusion: In our review there does not seem to be a clear link as to the definite cause of the MPCS. While the relationships to tuberculosis and autoimmunity seem to be often emphasized, there was no clear association with either etiology.Dermatology
Source: Dermatology - October 4, 2018 Category: Dermatology Source Type: research

Work ability before and after sarcoidosis diagnosis in Sweden
Information on how sarcoidosis affects one's ability to work is needed to clarify the burden of disease on the individual and society. Our aim was to describe the work ability of individuals with sarcoidosis before and after diagnosis compared to people without sarcoidosis.
Source: Respiratory Medicine - October 4, 2018 Category: Respiratory Medicine Authors: Elizabeth V. Arkema, Anders Eklund, Johan Grunewald, Gustaf Bruze Source Type: research

Macrophage Polarization in Sarcoidosis: An Unexpected Accomplice?
PMID: 30281325 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory Cell and Molecular Biology - October 3, 2018 Category: Molecular Biology Authors: Standiford TJ Tags: Am J Respir Cell Mol Biol Source Type: research

Pirfenidone-Induced Sarcoid-Like Reaction: A Novel Complication.
We describe the development of lymphadenopathy or a sarcoid-like reaction following initiation of pirfenidone, a complication not previously reported. PMID: 30290953 [PubMed - in process]
Source: Chest - October 1, 2018 Category: Respiratory Medicine Authors: Kolaitis NA, Kukreja J, Jones KD, Hays SR, Leard LE Tags: Chest Source Type: research

Significant elevation of the levels of B-cell activating factor (BAFF) in patients with sarcoidosis
This study demonstrated that the BAFF levels in both the serum and BALF were positively correlated with the disease activity markers and disease severity. BAFF may be useful as an indicator of both the disease activity and severity.
Source: Clinical Rheumatology - October 1, 2018 Category: Rheumatology Source Type: research

Needs, Perceptions and Education in Sarcoidosis: A Live Interactive Survey of Patients and Partners
This study improves awareness of needs and perceptions of patients with sarcoidosis and their partners. Sarcoidosis leads to anxiety and psychological distress and impairs well-being of patients and their partners. Attention for psychological support, better disease education, and more supportive care for partners is warranted.
Source: Lung - October 1, 2018 Category: Respiratory Medicine Source Type: research

Sarcoidosis triggered by immune checkpoint blockade.
Authors: Heppt M, Niesert AC, Flaig M, Berking C PMID: 30264301 [PubMed - in process]
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - September 29, 2018 Category: Dermatology Tags: Hautarzt Source Type: research

Advanced pulmonary sarcoidosis: long-term follow-up of 10 years or more.
Conference abstracts
Source: The Aspergillus Website - updates - September 27, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Echocardiography in Sarcoidosis
AbstractPurpose of ReviewCardiac sarcoidosis (CS) is associated with significant morbidity and mortality. The diagnosis of CS is challenging and typically one that is only entertained after many other conditions have been ruled out. A high index of suspicion is necessary in order to correctly determine appropriate testing for the disease. Transthoracic echocardiography is the most readily available imaging modality available to help establish a diagnosis in a potential patient. However, no one echocardiographic feature is pathognomonic.Recent FindingsOn echocardiography, unusual wall motion abnormalities, which do not fit ...
Source: Current Cardiology Reports - September 26, 2018 Category: Cardiology Source Type: research

Sarcoidosis: proteomics and new perspectives for improving personalized medicine.
Abstract INTRODUCTION: Through synergistic approaches integrating biomedical data from omics sciences to the clinical practice, precision medicine aims at more accurate identification of risk factors, characterization of endotypes, patient stratification, establishment of individualized therapy, and prediction of outcomes. Areas covered: This review evaluates the potential role of different -omics approaches for the development and application of Precision Medicine to sarcoidosis patients. This systemic and heterogeneous inflammatory disease is of unknown aetiology, affects people of any age and requires genotypic...
Source: Genomics Proteomics ... - September 25, 2018 Category: Genetics & Stem Cells Authors: Landi C, Carleo A, Cillis G, Rottoli P Tags: Expert Rev Proteomics Source Type: research

Cardiac Sarcoidosis Presenting as Complete Atrioventricular Block: Findings on PET/MRI.
Authors: Lee CH, Son JW, Kong EJ PMID: 30238713 [PubMed]
Source: Korean Circulation Journal - September 22, 2018 Category: Cardiology Tags: Korean Circ J Source Type: research

Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Using 19-G Needle for Sarcoidosis
Conclusion: This series reports a higher diagnostic yield than most other published studies and opens platform for direct comparison of each available needle. It also adds to the safety data for this larger needle. In addition, it raises doubt into utility of TBLB for diagnosis of sarcoidosis, which can increase the procedural complications.
Source: Journal of Bronchology and Interventional Pulmonology - September 22, 2018 Category: Respiratory Medicine Tags: Original Investigations Source Type: research

Pretesticular and Testicular Effects of Systemic Sarcoidosis: A Case Report.
Conclusion: This case illustrates the difficulties faced in managing the fertility of men who develop systemic sarcoidosis. It also highlights the diagnostic and therapeutic challenges faced by physicians when presented with a case of systemic sarcoidosis. PMID: 30230796 [PubMed - in process]
Source: Journal of Reproductive Medicine - September 22, 2018 Category: Reproduction Medicine Tags: J Reprod Med Source Type: research

Sarcoidosis related uveitis: Clinical presentations, disease course and rates of systemic disease progression after uveitis diagnosis
To document the clinical presentation, treatment and visual outcome of sarcoid uveitis and to determine the timing and potential risk factors of sarcoidosis progression to symptomatic systemic disease from the time of sarcoid uveitis diagnosis.
Source: American Journal of Ophthalmology - September 20, 2018 Category: Opthalmology Authors: Shirley Ma, Sophie L. Rogers, Anthony J. Hall, Lauren Hodgson, Jessica Brennan, Richard Stawell, Lyndell L. Lim Tags: Original Articles Source Type: research