High-dose (40 mg) versus low-dose (20 mg) prednisolone for treating sarcoidosis: a randomised trial (SARCORT trial)
Background Current guidelines recommend 20–40 mg·day–1 of oral prednisolone for treating pulmonary sarcoidosis. Whether the higher dose (40 mg·day–1) can improve outcomes remains unknown. Methods We conducted an investigator-initiated, single-centre, open-label, parallel-group, randomised controlled trial (ClinicalTrials.gov identifier NCT03265405). Consecutive subjects with pulmonary sarcoidosis were randomised (1:1) to receive either high-dose (40 mg·day–1 initial dose) or low-dose (20 mg·day–1 initial dose) oral prednisolone, tapered over 6&n...
Source: European Respiratory Journal - September 9, 2023 Category: Respiratory Medicine Authors: Dhooria, S., Sehgal, I. S., Agarwal, R., Muthu, V., Prasad, K. T., Dogra, P., Debi, U., Garg, M., Bal, A., Gupta, N., Aggarwal, A. N. Tags: Interstitial and orphan lung disease Original Articles: Sarcoidosis and pharmacotherapy Source Type: research

Imaging diagnostics of cardiac sarcoidosis
Herz. 2023 Sep 8. doi: 10.1007/s00059-023-05208-z. Online ahead of print.ABSTRACTCardiac involvement is clinically apparent in approximately 5% of all patients with systemic sarcoidosis, whereas evidence of cardiac involvement by imaging studies can be found in approximately 20% of cases. Occasionally, isolated cardiac sarcoidosis is encountered and is the only sign of the disease. The most frequent cardiac manifestations of the multifocal granulomatous inflammation include atrioventricular (AV) blocks and other conduction disorders, ventricular arrhythmias, sudden cardiac death and left and right ventricular wall disorder...
Source: Herz - September 8, 2023 Category: Cardiology Authors: Ron Blankstein Stephan Achenbach Source Type: research

Peritoneal sarcoidosis that simulates peritoneal carcinomatosis: a case report
Cir Cir. 2023;91(4):567-570. doi: 10.24875/CIRU.21000715.ABSTRACTSarcoidosis is a multisystem inflammatory disorder of unknown cause characterized by the formation of pleomorphic, non-caseating granulomas with predominantly pulmonary involvement. Although abdominal sarcoidosis represents 30% of extrapulmonary manifestations, peritoneal involvement is extremely rare. We will describe a rare case of peritoneal sarcoidosis simulating carcinomatosis in a young patient with abdominal pain who underwent laparoscopic examination.PMID:37677938 | DOI:10.24875/CIRU.21000715
Source: Cirugia y Cirujanos - September 7, 2023 Category: Surgery Authors: Julieta Zanatta-Scattolini Cecilia I Rodr íguez-Oses Jos é G Yaryura-Montero Juan A Albiero Jorge O Flores Carlos I Ferrero Source Type: research

Tachycardie ventriculaire r écidivante révélant une sarcoïdose cardiaque: Cardiac sarcoidosis revealed by recurrent ventricular tachycardia
We report here the case of a young woman with cardiac sarcoidosis of difficult diagnosis, revealed by a myocardial infarction with normal coronary angiography and recurrent ventricular tachycardia. Multimodal imaging, combined with left ventricular endomyocardial biopsies guided by electrophysiological analysis and endocavitary mapping, finally confirmed the diagnosis, and allowed effective medical treatment.PMID:37677913 | DOI:10.1016/j.ancard.2023.101644
Source: Annales de Cardiologie et d'Angeiologie - September 7, 2023 Category: Cardiology Authors: Alois Castro Floriane Gilles Sonia Marrakchi Thibaut Wajchert Philippe Rouvier Fleur Cohen-Aubart G éraldine Gibault-Genty Jean-Louis Georges Source Type: research

SACE and IL-2R as serum biomarkers for evaluation of multi-organ involvement and prognosis of sarcoidosis
CONCLUSION: SACE and IL-2R were useful as serum biomarkers in the initial evaluation of organ involvement as well as monitoring prognosis in sarcoidosis.PMID:37679741 | DOI:10.1186/s12931-023-02524-0
Source: Respiratory Care - September 7, 2023 Category: Respiratory Medicine Authors: Ying Zhou Xianqiu Chen Mengmeng Zhao Elyse E Lower Robert P Baughman Source Type: research

Peritoneal sarcoidosis that simulates peritoneal carcinomatosis: a case report
Cir Cir. 2023;91(4):567-570. doi: 10.24875/CIRU.21000715.ABSTRACTSarcoidosis is a multisystem inflammatory disorder of unknown cause characterized by the formation of pleomorphic, non-caseating granulomas with predominantly pulmonary involvement. Although abdominal sarcoidosis represents 30% of extrapulmonary manifestations, peritoneal involvement is extremely rare. We will describe a rare case of peritoneal sarcoidosis simulating carcinomatosis in a young patient with abdominal pain who underwent laparoscopic examination.PMID:37677938 | DOI:10.24875/CIRU.21000715
Source: Cirugia y Cirujanos - September 7, 2023 Category: Surgery Authors: Julieta Zanatta-Scattolini Cecilia I Rodr íguez-Oses Jos é G Yaryura-Montero Juan A Albiero Jorge O Flores Carlos I Ferrero Source Type: research

Tachycardie ventriculaire r écidivante révélant une sarcoïdose cardiaque: Cardiac sarcoidosis revealed by recurrent ventricular tachycardia
We report here the case of a young woman with cardiac sarcoidosis of difficult diagnosis, revealed by a myocardial infarction with normal coronary angiography and recurrent ventricular tachycardia. Multimodal imaging, combined with left ventricular endomyocardial biopsies guided by electrophysiological analysis and endocavitary mapping, finally confirmed the diagnosis, and allowed effective medical treatment.PMID:37677913 | DOI:10.1016/j.ancard.2023.101644
Source: Annales de Cardiologie et d'Angeiologie - September 7, 2023 Category: Cardiology Authors: Alois Castro Floriane Gilles Sonia Marrakchi Thibaut Wajchert Philippe Rouvier Fleur Cohen-Aubart G éraldine Gibault-Genty Jean-Louis Georges Source Type: research

Peritoneal sarcoidosis that simulates peritoneal carcinomatosis: a case report
Cir Cir. 2023;91(4):567-570. doi: 10.24875/CIRU.21000715.ABSTRACTSarcoidosis is a multisystem inflammatory disorder of unknown cause characterized by the formation of pleomorphic, non-caseating granulomas with predominantly pulmonary involvement. Although abdominal sarcoidosis represents 30% of extrapulmonary manifestations, peritoneal involvement is extremely rare. We will describe a rare case of peritoneal sarcoidosis simulating carcinomatosis in a young patient with abdominal pain who underwent laparoscopic examination.PMID:37677938 | DOI:10.24875/CIRU.21000715
Source: Cirugia y Cirujanos - September 7, 2023 Category: Surgery Authors: Julieta Zanatta-Scattolini Cecilia I Rodr íguez-Oses Jos é G Yaryura-Montero Juan A Albiero Jorge O Flores Carlos I Ferrero Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20