This page shows you the latest news items in this category. This is page number 3.

Total 4716 results found since Jan 2013.

Cutaneous sarcoidosis: a new subset in the spectrum of paraneoplastic dermatoses
Clinical and Experimental Dermatology, EarlyView.
Source: Clinical And Experimental Dermatology - May 20, 2018 Category: Dermatology Authors: M. El ‐Khalawany , A. Mosbeh , S. Aboeldahab , S. Ali Source Type: research

Muscular sarcoidosis under anti TNF treatment in ankylosing spondylitis
Publication date: Available online 19 May 2018 Source:Joint Bone Spine Author(s): Daniel Wendling, Jean-Philippe Nueffer
Source: Joint Bone Spine - May 20, 2018 Category: Orthopaedics Source Type: research

Should Conjunctival Biopsy Be Performed for Definitive Diagnosis of Sarcoidosis?
No abstract available
Source: Journal of Neuro-Ophthalmology - May 18, 2018 Category: Opthalmology Tags: Point Counter-Point Source Type: research

Cardiac sarcoidosis: a challenging diagnosis
Source: Clinical Research in Cardiology - May 18, 2018 Category: Cardiology Source Type: research

Sahlgrenska Cardiomyopathy Project
Conditions:   Dilated Cardiomyopathies;   Hypertrophic Cardiomyopathy;   Restrictive Cardiomyopathy;   Arrhythmogenic Right Ventricular Cardiomyopathy;   Myocarditis;   Sarcoidosis With Myocarditis;   Giant Cell Myocarditis;   Amyloidosis; Heart (Manifestation) Intervention:   Sponsors:   Göteborg University;   Sahlgrenska University Hospital, Sweden Not yet recruiting
Source: ClinicalTrials.gov - May 17, 2018 Category: Research Source Type: clinical trials

Sarcoid ‐resembling granulomatous lung disease secondary to occupational magnetite iron dust exposure
Respirology Case Reports,Volume 6, Issue 6, August 2018.
Source: Respirology Case Reports - May 17, 2018 Category: Respiratory Medicine Authors: Lewis Xiao , Anil Kookana , Robert McClure , Subash Heraganahally Source Type: research

Joint recommendations for retinal screening in long-term users of hydroxychloroquine and chloroquine in the United Kingdom (2018).
This article is protected by copyright. All rights reserved. PMID: 29770429 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - May 16, 2018 Category: Dermatology Authors: Yusuf IH, Lotery AJ, Ardern-Jones MR Tags: Br J Dermatol Source Type: research

Trident sign trumps Aquaporin-4-IgG ELISA in diagnostic value in a case of longitudinally extensive transverse myelitis
We report a case in which the patient was initially diagnosed with neuromyelitis optical spectrum disorder, but where the “trident” sign ultimately led to the correct diagnosis of spinal cord sarcoidosis.
Source: Multiple Sclerosis and Related Disorders - May 15, 2018 Category: Neurology Source Type: research

Oral Fumaderm ® to treat cutaneous sarcoidosis
Clinical and Experimental Dermatology, EarlyView.
Source: Clinical And Experimental Dermatology - May 14, 2018 Category: Dermatology Authors: S. Rolls , W. Porter Source Type: research

Pathology after a combination of sequential and simultaneous unipolar radiofrequency ablation of ventricular tachycardia in a postmortem heart with cardiac sarcoidosis
Clinical Case Reports, EarlyView.
Source: Clinical Case Reports - May 9, 2018 Category: General Medicine Authors: KojiMiyamoto , Taka ‐akiMatsuyama , TakashiNoda , HatsueIshibashi‐Ueda , KengoKusano Source Type: research

Musculoskeletal and rheumatic diseases induced by immune checkpoint inhibitors: a review of the literature.
CONCLUSIONS: Newly induced musculoskeletal and rheumatic diseases are a frequent adverse event associated with immune checkpoint inhibitors treatment. PMID: 29745339 [PubMed - as supplied by publisher]
Source: Current Drug Safety - May 8, 2018 Category: Drugs & Pharmacology Authors: Benfaremo D, Manfredi L, Luchetti MM, Gabrielli A Tags: Curr Drug Saf Source Type: research

18F-FDG PET/CT helps in unmasking the great mimicker: A case of neurosarcoidosis with isolated involvement of the spinal cord
Publication date: May–June 2018 Source:Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), Volume 37, Issue 3 Author(s): A. Gholamrezanezhad, L. Mehta A 36 year-old male with no significant past medical history presented with lower extremity numbness, gait instability, and urinary and bowel retention of 4 weeks onset. Spine MRI revealed diffuse oedema of cervicothoracic spinal cord with several solid enhancing intramedullary lesions, suggestive of metastases. The 18F-FDG PET/CT performed to identify the primary malignancy demonstrated mild hypermetabolic foci within the cervicothoracic cord, as w...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - May 3, 2018 Category: Nuclear Medicine Source Type: research

Ipilimumab-Induced Sarcoidosis and Thyroiditis
No abstract available
Source: American Journal of Therapeutics - May 1, 2018 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research

A cavernous sinus lesion clinically responsive to steroids
We describe a patient presenting with neurologic symptoms referable to a persistent unilateral cavernous sinus MRI abnormality, initially thought to be consistent with Tolosa-Hunt syndrome, that was clinically but not radiographically responsive to steroids. Following reevaluation due to the presence of new symptoms, pathology revealed that the abnormality was most consistent with chordoma, a rare skull based tumor. In patients with a presumed diagnosis of Tolosa-Hunt syndrome, close clinical and radiographic follow-up is imperative, with early consideration for biopsy in patients that fail to respond to treatment both cli...
Source: Journal of Clinical Neuroscience - May 1, 2018 Category: Neuroscience Source Type: research

What Causes Flushing?
Discussion Flushing is usually thought of as a benign condition such as blushing, but can be quite irritating if it is frequent or persistent (i.e. menopausal hot flashes) or even pathologic (i.e. malignancy). “Flushing is a subjective and sensation of warmth that is accompanied by reddening of the skin anywhere on the body but favors the face, neck, and upper torso…. Flushing can be broadly divided into episodic or persistent. Episodic flashing is mediated by the release of endogenous vasoactive mediators or medications, while persistent flushing result in a fixed facial erythema with telangiectasias and cyano...
Source: PediatricEducation.org - April 30, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

941 Molecular, physiological, and pathological backgrounds of recently proposed three subspecies of Propionibacterium acnes
Propionibacterium acnes (Cutibacterium acnes) is a predominating bacterial species on the human skin, which is considered to have a role in developing acne vulgaris, SAPHO syndrome, sarcoidosis, and various deep tissue infections. Very recently, the three types of the species are given the official recognition as three distinct subspecies ( Dekio et al. 2015 McDowell et al. 2016 ). This status is a triumph of the continuous research into the nature of these types since they were coined decades ago.
Source: Journal of Investigative Dermatology - April 27, 2018 Category: Dermatology Authors: I. Dekio, M. Sakamoto, Y. Murakami, M. Ohkuma Tags: Innate Immunity, Microbiology, Inflammation Source Type: research

Value of 18-F-FDG PET/CT in assessment of patients with fever of unknown origin
Conclusion 18F-FDG PET/CT can be a useful tool for scanning the whole body to suggest the FUO cause.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - April 27, 2018 Category: Nuclear Medicine Source Type: research

Ex-vivo Production of Regulatory B-Cells for Use in Auto-immune Diseases
Regulatory B-cells (Breg) play an important role in reducing autoimmunity and reduced levels of these cells are implicated in etiology of several auto-inflammatory diseases. Despite their impact in many diseases, their physiological inducers are unknown.   Given that Bregs are a very rare B-cell, identifying factors that promote their development would allow in vivo modulation of Breg levels and ex-vivo production of large amounts of antigen-specific Bregs to use in immunotherapy for auto-inflammatory diseases.  Researchers at NEI ' sMolecular Immunology Section developed a method for theex-vivo production of Breg. The ...
Source: NIH OTT Licensing Opportunities - April 26, 2018 Category: Research Authors: ajoyprabhu3 Source Type: research

Heart Transplantation for End Stage Cardiac Sarcoidosis: Increasingly Used with Excellent Results
Publication date: Available online 25 April 2018 Source:Canadian Journal of Cardiology Author(s): Mustafa Toma, David Birnie
Source: Canadian Journal of Cardiology - April 26, 2018 Category: Cardiology Source Type: research

Drug-induced sarcoidosis-like reactions (DISR).
Abstract A drug-induced sarcoidosis-like reaction (DISR) is a systemic granulomatous reaction that is indistinguishable from sarcoidosis and occurs in temporal relationship with initiation of an offending drug. DISRs typically improve or resolve after the withdrawal of offending drug. Four common categories of drugs that have been associated with the development of a DISR are immune checkpoint inhibitors (ICIs), highly active anti-retroviral therapy (HAART), interferons (IFNs) and tumor necrosis factor alpha antagonists (TNF-alpha antagonists). Similar to sarcoidosis, DISRs do not necessarily require treatment, as...
Source: Chest - April 23, 2018 Category: Respiratory Medicine Authors: Chopra A, Nautiyal A, Kalkanis A, Judson MA Tags: Chest Source Type: research

437 Efficacy and safety of tumor necrosis factor inhibitors in cutaneous sarcoidosis: A systematic review
Sarcoidosis is a multisystem disease of unknown etiology characterized by noncaseating granulomas that often affect the skin. Tumor necrosis factor (TNF) is essential in formation of granulomas. Growing evidence supports anti-TNF agents for refractory sarcoidosis, including infliximab (IFX), etanercept, adalimumab ( ADA ), golimumab (GOL) and certolizumab. We sought to characterize the efficacy and safety of anti-TNF in all types of sarcoidosis by performing a systematic review that included trials and case series.
Source: Journal of Investigative Dermatology - April 19, 2018 Category: Dermatology Authors: B. Adler, C. Wang, T. Bui, H. Schilperoort, A.W. Armstrong Tags: Clinical Research: Pathophysiology and Therapeutics Source Type: research

Childhood Sarcoidosis Presenting as Recurrent Facial Palsy.
Abstract BACKGROUND: Recurrent facial palsy in a patient merits investigation for underlying etiology. CASE CHARACTERISTICS: 8-year-old boy with erythematous itchy skin lesion and recurrent facial palsy. OBSERVATION: He had a past history of aseptic meningitis and nephrocalcinosis. Raised angiotensin converting enzyme levels, interstitial lung disease on CT chest, and non caseating granulomas on skin biopsy clinched the diagnosis of sarcoidosis. MESSAGE: Multisystem involvement and recurrent lower motor facial nerve palsy is a clinical clue for sarcoidosis. PMID: 29726829 [PubMed - in process]
Source: Indian Pediatrics - April 15, 2018 Category: Pediatrics Authors: Passi GR, Arora K, Gokhale N Tags: Indian Pediatr Source Type: research

Serial observation of electrocardiographic responses to corticosteroid therapy in a patient with right ventricular-predominant cardiac sarcoidosis
Predominant or isolated right ventricular involvement in cardiac sarcoidosis is uncommon, but should always be considered in a case of right ventricular hypertrophy combined with ventricular arrhythmia and/or conduction disturbance. Although improvement in right ventricular hypertrophy and atrioventricular conduction disturbance following corticosteroid therapy has been reported, the detailed serial electrocardiographic responses during corticosteroid therapy, as well as temporal changes in the electrocardiographic, biochemical, and morphological responses, have not been reported.
Source: Journal of Electrocardiology - April 11, 2018 Category: Cardiology Authors: Hiroyuki Toh, Shumpei Mori, Marika Keno, Shun Yokota, Yuto Shinkura, Yu Izawa, Yuichi Nagamatsu, Shinsuke Shimoyama, Koji Fukuzawa, Tomofumi Doi, Ken-ichi Hirata Source Type: research

Perioperative onset of sarcoidosis : Rare differential diagnosis of a  difficult airway.
This article describes the onset of sarcoidosis in a case of an unexpected difficult airway. PMID: 29644445 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - April 11, 2018 Category: Anesthesiology Authors: Jansen G, Nowak A Tags: Anaesthesist Source Type: research

The Fear of Lymphadenopathy: A Cautionary Case of Sarcoidosis Masquerading as Recurrent Diffuse Large B-cell Lymphoma (DLBCL)
We describe the cautionary case of a patient with advanced-stage large B-cell lymphoma (DLBCL). After combination chemotherapy, CT-PET revealed a persistent focus of likely DLBCL for which he received radiotherapy. Follow-up CT-PET showed diffuse hypermetabolic adenopathy and recurrent DLBCL was presumed. As part of clinical trial assessment, multiple biopsies showed non-caseating lymphadenitis consistent with sarcoidosis. No treatment for asymptomatic sarcoidosis was required and 18 months later he remains cancer-free. The presentation of sarcoidosis masquerading as recurrent DLBCL highlights the importance of tissue samp...
Source: Leukemia Research Reports - April 9, 2018 Category: Hematology Source Type: research

Clinical presentation, management and prognosis of patients with cardiac sarcoidosis.
CONCLUSION: In CS patients, ventricular arrhythmias and impairment of LVEF were frequently seen, but the medium-term survival was excellent on heart failure therapy and immunosuppression. FUNDING: none. TRIAL REGISTRATION: Danish Data Protection Agency: (File no. RH-2016-301, I-Suite no. 04965). PMID: 29619923 [PubMed - in process]
Source: Danish Medical Journal - April 7, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Pulmonary sarcoidosis
Publication date: Available online 3 April 2018 Source:The Lancet Respiratory Medicine Author(s): Paolo Spagnolo, Giulio Rossi, Rocco Trisolini, Nicola Sverzellati, Robert P Baughman, Athol U Wells Sarcoidosis is a granulomatous disease of unknown cause, occurs worldwide and has a highly variable prevalence. The disease is typically dominant in the lungs, although it can affect virtually any organ and is unpredictable in its clinical course. The severity of pulmonary sarcoidosis ranges from incidentally discovered radiographic abnormalities in asymptomatic patients to a chronic progressive disease that is refractory to tr...
Source: The Lancet Respiratory Medicine - April 4, 2018 Category: Respiratory Medicine Source Type: research

Ocular Involvement in Sarcoidosis.
Authors: Raevis JJ, Antonova N, Agemy S PMID: 29606646 [PubMed - in process]
Source: Journal of Rheumatology - April 3, 2018 Category: Rheumatology Tags: J Rheumatol Source Type: research

Prevalence, incidence, and mortality of sarcoidosis in Korea, 2003 –2015: A nationwide population-based study
This study evaluated the incidence, prevalence, and mortality of sarcoidosis in a large nationwide population-based cohort in Korea.
Source: Respiratory Medicine - April 2, 2018 Category: Respiratory Medicine Authors: Ji Eun Park, Young Sam Kim, Min Jin Kang, Cheong Ju Kim, Chang Hoon Han, Sun Min Lee, Seon Cheol Park Source Type: research

Occupational exposure as a presumable cause of subcutaneous sarcoidosis in a tannery worker - case report and review of the literature.
Authors: Michalska-Jakubus MM, Zdeb K, Rymgayłło-Jankowska B, Korolczuk A, Żarnowski T, Krasowska D PMID: 29599684 [PubMed]
Source: Advances in Dermatology and Allergology - April 1, 2018 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Sarcoidosis in World Trade Center-Exposed Firefighters.
PMID: 29626952 [PubMed - in process]
Source: Chest - April 1, 2018 Category: Respiratory Medicine Authors: Reich JM Tags: Chest Source Type: research

Symptomatic hypercalcemia and scarring alopecia as presenting features of sarcoidosis.
We report here a case of sarcoidosis presenting with severe symptomatic hypercalcemia (>14 mg/dL, 3.5 mmol/L), scarring alopecia, and acute-on-chronic kidney failure. PMID: 29706828 [PubMed]
Source: Baylor University Medical Center Proceedings - April 1, 2018 Category: Universities & Medical Training Authors: Frieder J, Kivelevitch D, Menter A Tags: Proc (Bayl Univ Med Cent) Source Type: research

Current management of sarcoidosis I: pulmonary, cardiac, and neurologic manifestations
Purpose of review Sarcoidosis is a systemic disease characterized by noncaseating granulomatous inflammation of multiple organ systems. Pulmonary, cardiac, and neurologic involvements have the worst prognosis. Current recommendations for the therapeutic management and follow-up of sarcoidosis involving these critical organs will be reviewed. Recent findings In those sarcoidosis patients requiring immunosuppressive therapy, corticosteroids are used first at varying doses depending on the presenting manifestation. Patients with symptomatic pulmonary, cardiac, or neurologic involvement will be maintained on corticosteroi...
Source: Current Opinion in Rheumatology - March 27, 2018 Category: Rheumatology Tags: CLINICAL THERAPEUTICS: Edited by William J. McCune Source Type: research

Sleep disturbance and symptom burden in sarcoidosis
Sarcoidosis is a systemic inflammatory disease associated with myriad symptoms, including fatigue. It can affect physiological processes like sleep, leading to poor sleep quality and excessive daytime sleepiness. We hypothesized that sarcoidosis patients would report more severe sleep disturbance than healthy controls and that relationships would be found with sleep disturbance and the severity of other symptoms.
Source: Respiratory Medicine - March 26, 2018 Category: Respiratory Medicine Authors: Bryan S. Benn, Zoe Lehman, Sharon A. Kidd, Christine Miaskowski, Bernie Y. Sunwoo, Melissa Ho, Sara Sun, Joris Ramstein, Jeffrey M. Gelfand, Laura L. Koth Source Type: research