This page shows you the latest news items in this category. This is page number 3.

Total 4942 results found since Jan 2013.

Neurosarcoidosis Flare with Multifocal Restricted Diffusion: Stroke, Inflammation, or Both?
We present a case of a patient with both leptomeningeal enhancement and multifocal restricted diffusion in a patient with sarcoidosis.
Source: Journal of Stroke and Cerebrovascular Diseases - July 25, 2018 Category: Neurology Authors: Elizabeth Spurgeon, Justin Abbatemarco, Richard Prayson, Mary Willis Tags: Case Report Source Type: research

Heart Transplantation for End-Stage Cardiac Sarcoidosis: Increasingly Used With Excellent Results
Publication date: August 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 8Author(s): Mustafa Toma, David Birnie
Source: Canadian Journal of Cardiology - July 24, 2018 Category: Cardiology Source Type: research

Policy paper nuclear cardiology - update 2018 - Current status of clinical practice.
Abstract The joint position paper of the working community "Cardiovascular Nuclear Medicine" of the German Society of Nuclear Medicine (DGN) and the working group "Nuclear Cardiology Diagnostics" of the German Cardiac Society (DKG) updates the former 2009 paper.It is the purpose of this paper to provide an overview about the application fields, the state-of-the-art and the current value of nuclear cardiology imaging. The topics covered are chronic coronary artery disease, including viability imaging, furthermore cardiomyopathies, infective endocarditis, cardiac sarcoidosis and amyloidosis. PMID: 30041259 [Pub...
Source: Nuklearmedizin - July 24, 2018 Category: Radiology Authors: Lindner O, Bauersachs J, Bengel FM, Burchert W, Vom Dahl J, Dörr R, Hacker M, Kelm M, Rassaf T, Rischpler C, Schäfer W, Schäfers MA, Silber S, Zimmermann R Tags: Nuklearmedizin Source Type: research

Isolated Mediastinal Lymphadenopathy Caused by Rhodococcus equi Infection
This report presents a case with isolated mediastinal lymphadenopathy caused by Rhodococcus equi infection in a 71-year-old immunocompetent patient.
Source: The Annals of Thoracic Surgery - July 23, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Treatment of Interstitial Lung Disease associated cough: CHEST guideline and expert panel report.
CONCLUSIONS: The evidence supporting the management of chronic cough in ILD is limited. This guideline presents suggestions for managing and treating cough on the best available evidence but future research is clearly needed. PMID: 30036496 [PubMed - as supplied by publisher]
Source: Chest - July 20, 2018 Category: Respiratory Medicine Authors: Birring SS, Kavanagh JE, Irwin RS, Keogh K, Lim KG, Ryu JH Tags: Chest Source Type: research

Gallium-68 DOTA-NOC PET/CT as an alternate predictor of disease activity in sarcoidosis
Introduction We evaluated the role of gallium-68-labeled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-Nal3-octreotide (68Ga-DOTA-NOC) PET/CT in assessing sarcoidosis disease activity. Patients and methods Patients diagnosed with sarcoidosis underwent 68Ga-DOTA-NOC-PET/CT. The maximum standardized uptake value (SUVmax) at the pathological site and in the descending thoracic aorta (reference standard, SUVmed) were assessed. A SUVmax/SUVmed ratio (disease activity score) of more than one was considered a marker of active disease and was compared with the clinical symptoms and serum angiotensin-converting ...
Source: Nuclear Medicine Communications - July 13, 2018 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Diagnostic Challenges in Granulomatous Uveitis: Tuberculosis or Sarcoidosis?
CONCLUSIONS: The diagnosis and correct therapeutic strategy of entities that fall in between tuberculosis and sarcoidosis still remains challenging, especially in patients coming from endemic areas. PMID: 29993306 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - July 12, 2018 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Infographic: Cardiac sarcoidosis
Learn more about Cardiac sarcoidosis. Other health tip infographics: mayohealthhighlights.startribune.com?
Source: News from Mayo Clinic - July 11, 2018 Category: Databases & Libraries Source Type: news

Sarcoidosis presenting as Wallenberg syndrome and panuveitis
We report a case of a patient who presented with the lateral medullary syndrome and panuveitis as her initial manifestation of sarcoidosis. The patient’s course was further complicated by renal involvement. Lacrimal gland and renal biopsies showed noncaseating granulomas without evidence of infection, establishing the diagnosis. Intracranial vertebral artery involvement was confirmed by brain imaging. Bilateral hilar lymphadenopathy with upper lobe predominant nodules on chest imaging was consistent with asymptomatic pulmonary involvement. Systemic steroid therapy is indicated for treatment of ocular sarcoidosis, with st...
Source: Respiratory Medicine Case Reports - July 10, 2018 Category: Respiratory Medicine Source Type: research

Cough in sarcoidosis patients
Publication date: Available online 4 January 2018Source: Respiratory Physiology & NeurobiologyAuthor(s): Eva Kovacova, Tomas Buday, Robert Vysehradsky, Jana PlevkovaAbstractSarcoidosis is a multi-system disease of unknown aetiology characterized by presence of non-caseating granulomatous inflammation. Cough is a common and significant symptom in sarcoidosis, reducing quality of life. Objective 24 h cough monitoring proved that sarcoidosis patients have significantly higher cough frequency compared to controls and their cough has diurnal variation, it is gender-specific and shows racial differences. It correlates with the...
Source: Respiratory Physiology and Neurobiology - July 10, 2018 Category: Respiratory Medicine Source Type: research

Uveitis and internuclear ophthalmoplegia as ocular manifestations of sarcoidosis
Publication date: April–June 2018Source: Saudi Journal of Ophthalmology, Volume 32, Issue 2Author(s): Daniele Cirone, Luca Cimino, Giovanni SpinucciAbstractSarcoidosis is a multisystemic granulomatous chronic disease of unknown etiology with a wide range of clinical presentations. Diagnosis of sarcoidosis in patients with ocular manifestations can be challenging.We first describe a case of sarcoidosis presented with pulmonary involvement and both uveitis and internuclear ophthalmoplegia as ocular manifestations.A 55-year-old caucasian woman with non-productive cough and weakness presented with bilateral granulomatous ant...
Source: Saudi Journal of Ophthalmology - July 10, 2018 Category: Opthalmology Source Type: research

Tubulointerstitial nephritis and uveitis (TINU) with granulomatosis: a novel report of simultaneous TINU and sarcoidosis in a pediatric patient
We report the case of a 7-year-old girl who presented with bilateral anterior uveitis, acute interstitial nephritis, and asymptomatic pulmonary granulomas and provide novel clinical evidence of an association between tubulointerstitial nephritis and uveitis syndrome and sarcoidosis.
Source: Journal of American Association for Pediatric Ophthalmology and Strabismus - July 10, 2018 Category: Opthalmology Source Type: research

The fear of lymphadenopathy: A cautionary case of sarcoidosis masquerading as recurrent diffuse large b-cell lymphoma (DLBCL)
We describe the cautionary case of a patient with advanced-stage large B-cell lymphoma (DLBCL). After combination chemotherapy, CT-PET revealed a persistent focus of likely DLBCL for which he received radiotherapy. Follow-up CT-PET showed diffuse hypermetabolic adenopathy and recurrent DLBCL was presumed. As part of clinical trial assessment, multiple biopsies showed non-caseating lymphadenitis consistent with sarcoidosis. No treatment for asymptomatic sarcoidosis was required and 18 months later he remains cancer-free. The presentation of sarcoidosis masquerading as recurrent DLBCL highlights the importance of tissue samp...
Source: Leukemia Research Reports - July 10, 2018 Category: Hematology Source Type: research

Management of cardiac sarcoidosis – A practical guide
Publication date: April 2018Source: Cor et Vasa, Volume 60, Issue 2Author(s): Petr Kopriva, Martin Griva, Zbynek TüdösAbstractSarcoidosis is a multi-system granulomatous disorder of unclear etiology which can affect any organ of the body including the heart. The heart is involved in up to 25% of sarcoidosis patients. In rare cases, the heart can be the only organ involved.Involvement of the heart, called cardiac sarcoidosis, especially if symptomatic, significantly deteriorates the prognosis for sarcoidosis patients, which is why cardiac sarcoidosis should be not only considered, but also searched for actively. Despite r...
Source: Cor et Vasa - July 10, 2018 Category: Cardiology Source Type: research

Sarcoidosis presenting as Wallenberg syndrome and panuveitis.
We report a case of a patient who presented with the lateral medullary syndrome and panuveitis as her initial manifestation of sarcoidosis. The patient's course was further complicated by renal involvement. Lacrimal gland and renal biopsies showed noncaseating granulomas without evidence of infection, establishing the diagnosis. Intracranial vertebral artery involvement was confirmed by brain imaging. Bilateral hilar lymphadenopathy with upper lobe predominant nodules on chest imaging was consistent with asymptomatic pulmonary involvement. Systemic steroid therapy is indicated for treatment of ocular sarcoidosis, with stan...
Source: Respiratory Care - July 7, 2018 Category: Respiratory Medicine Authors: Oks M, Li A, Makaryus M, Pomeranz HD, Sachdeva M, Pullman J, Schwartz D, Steinberg H Tags: Respir Med Case Rep Source Type: research

Coexistence of sarcoidosis and Hashimoto thyroiditis.
Abstract Sarcoidosis is a chronic, inflammatory disease with unknown cause characterized by non-caseating granuloma formations. It can present with bilateral hilar lymphadenopathy, skin lesions, eye involvement and locomotor system findings. Hashimoto thyroiditis is an organ-specific autoimmune disease characterized by increased autoantibody synthesis. Sarcoidosis can involve different endocrine glands. Thyroid gland involvement may lead to increased thyroid function disorders and autoantibodies. Herein, we report an 80-year-old female patient with sarcoidosis and Hashimoto coexistence. PMID: 29976045 [PubMed - in process]
Source: Reumatismo - July 6, 2018 Category: Rheumatology Authors: Semiz H, Yalcin M, Kobak SV Tags: Reumatismo Source Type: research

Sarcoidosis presenting as Wallenberg syndrome and panuveitis
We report a case of a patient who presented with the lateral medullary syndrome and panuveitis as her initial manifestation of sarcoidosis. The patient’s course was further complicated by renal involvement. Lacrimal gland and renal biopsies showed noncaseating granulomas without evidence of infection, establishing the diagnosis. Intracranial vertebral artery involvement was confirmed by brain imaging. Bilateral hilar lymphadenopathy with upper lobe predominant nodules on chest imaging was consistent with asymptomatic pulmonary involvement. Systemic steroid therapy is indicated for treatment of ocular sarcoidosis, with st...
Source: Respiratory Medicine Case Reports - July 5, 2018 Category: Respiratory Medicine Source Type: research

Cough in sarcoidosis patients
Publication date: Available online 4 January 2018Source: Respiratory Physiology & NeurobiologyAuthor(s): Eva Kovacova, Tomas Buday, Robert Vysehradsky, Jana PlevkovaAbstractSarcoidosis is a multi-system disease of unknown aetiology characterized by presence of non-caseating granulomatous inflammation. Cough is a common and significant symptom in sarcoidosis, reducing quality of life. Objective 24 h cough monitoring proved that sarcoidosis patients have significantly higher cough frequency compared to controls and their cough has diurnal variation, it is gender-specific and shows racial differences. It correlates with the...
Source: Respiratory Physiology and Neurobiology - July 5, 2018 Category: Respiratory Medicine Source Type: research

Uveitis and internuclear ophthalmoplegia as ocular manifestations of sarcoidosis
Publication date: April–June 2018Source: Saudi Journal of Ophthalmology, Volume 32, Issue 2Author(s): Daniele Cirone, Luca Cimino, Giovanni SpinucciAbstractSarcoidosis is a multisystemic granulomatous chronic disease of unknown etiology with a wide range of clinical presentations. Diagnosis of sarcoidosis in patients with ocular manifestations can be challenging.We first describe a case of sarcoidosis presented with pulmonary involvement and both uveitis and internuclear ophthalmoplegia as ocular manifestations.A 55-year-old caucasian woman with non-productive cough and weakness presented with bilateral granulomatous ant...
Source: Saudi Journal of Ophthalmology - July 5, 2018 Category: Opthalmology Source Type: research

Tubulointerstitial nephritis and uveitis (TINU) with granulomatosis: a novel report of simultaneous TINU and sarcoidosis in a pediatric patient
We report the case of a 7-year-old girl who presented with bilateral anterior uveitis, acute interstitial nephritis, and asymptomatic pulmonary granulomas and provide novel clinical evidence of an association between tubulointerstitial nephritis and uveitis syndrome and sarcoidosis.
Source: Journal of American Association for Pediatric Ophthalmology and Strabismus - July 5, 2018 Category: Opthalmology Source Type: research

The fear of lymphadenopathy: A cautionary case of sarcoidosis masquerading as recurrent diffuse large b-cell lymphoma (DLBCL)
We describe the cautionary case of a patient with advanced-stage large B-cell lymphoma (DLBCL). After combination chemotherapy, CT-PET revealed a persistent focus of likely DLBCL for which he received radiotherapy. Follow-up CT-PET showed diffuse hypermetabolic adenopathy and recurrent DLBCL was presumed. As part of clinical trial assessment, multiple biopsies showed non-caseating lymphadenitis consistent with sarcoidosis. No treatment for asymptomatic sarcoidosis was required and 18 months later he remains cancer-free. The presentation of sarcoidosis masquerading as recurrent DLBCL highlights the importance of tissue samp...
Source: Leukemia Research Reports - July 5, 2018 Category: Hematology Source Type: research

Management of cardiac sarcoidosis – A practical guide
Publication date: April 2018Source: Cor et Vasa, Volume 60, Issue 2Author(s): Petr Kopriva, Martin Griva, Zbynek TüdösAbstractSarcoidosis is a multi-system granulomatous disorder of unclear etiology which can affect any organ of the body including the heart. The heart is involved in up to 25% of sarcoidosis patients. In rare cases, the heart can be the only organ involved.Involvement of the heart, called cardiac sarcoidosis, especially if symptomatic, significantly deteriorates the prognosis for sarcoidosis patients, which is why cardiac sarcoidosis should be not only considered, but also searched for actively. Despite r...
Source: Cor et Vasa - July 5, 2018 Category: Cardiology Source Type: research

Atypical CT findings of pulmonary sarcoidosis: A case report
Rationale: Pulmonary involvement occurs in about 90% of patients with sarcoidosis. However, delayed diagnosis sometimes occurs due to atypical thoracic imaging findings. Patient concerns: A 52-year-old woman presented with recurrent uveitis and fever of unknown origin. She had been admitted to the hospital due to fever, but its cause was not determined. Diagnoses: Chest computed tomography (CT) revealed a solitary pulmonary nodule and an enlarged right axillary lymph node. The nodule had showed an interval growth from 0.7 cm to 1.1 cm over 18 months, when compared to the previous chest CT. Mosaic attenuation wa...
Source: Medicine - July 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Focal Myocardial Damage in Cardiac Sarcoidosis Characterized by Strain Analysis on Magnetic Resonance Tagged Imaging in Comparison with Fluorodeoxyglucose Positron Emission Tomography Accumulation and Magnetic Resonance Late Gadolinium Enhancement
Objective The aims of this study were to characterize focal myocardial damage of cardiac sarcoidosis by strain analysis and to compare it with late gadolinium enhancement (LGE) and fluorodeoxyglucose (FDG) positron emission tomography. Methods We reviewed 208 segments from 13 cardiac sarcoidosis patients and measured the circumferential strain (Ecc) and the strain change per second (Ecc rate). The mean Ecc and Ecc rate values were compared between the FDG(+) and FDG(−), and the LGE(+) and LGE(−) segments using Welch's t test. Results The peak and max Ecc rates were better in the LGE(−) segments than in the LG...
Source: Journal of Computer Assisted Tomography - July 1, 2018 Category: Radiology Tags: Cardiothoracic Imaging Source Type: research

Sarcoidosis in Patients with Antisynthetase Syndrome: Presentation and Outcome.
CONCLUSION: Sarcoidosis may be underdiagnosed in patients with AS. PMID: 29961694 [PubMed - as supplied by publisher]
Source: J Rheumatol - July 1, 2018 Category: Rheumatology Authors: Couture P, Brillet PY, Varin S, Le Goff B, Meyer A, Sibilia J, Jouneau S, Valeyre D, Hervier B, Uzunhan Y Tags: J Rheumatol Source Type: research

Effect of Needle Size in Diagnostic Yield of EBUS-TBNA in Sarcoidosis and Lymphoma
Conditions:   Sarcoidosis;   Lymphoma;   Adenopathy Hilar Interventions:   Device: ViziShot FLEX 19G needle;   Device: Vizishot 22G needle (standard) Sponsor:   Centre hospitalier de l'Université de Montréal (CHUM) Not yet recruiting
Source: ClinicalTrials.gov - June 29, 2018 Category: Research Source Type: clinical trials

The importance of histopathology in the diagnosis of isolated renal sarcoidosis: a case report.
CONCLUSIONS: The use of histopathology together with clinical and laboratory data to diagnose isolated renal sarcoidosis, rule out other etiologies and introduce early treatment is of paramount importance. PMID: 29944158 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - June 29, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Propionibacterium acnes Septic Pericarditis in a Patient With Sarcoidosis and Acne
We present the first case of infective pericarditis caused by P. acnes in a man with acne and severe sarcoidosis. This case emphasizes the importance of considering this microorganism as a causative agent of pericarditis in this setting.
Source: Infectious Diseases in Clinical Practice - June 28, 2018 Category: Infectious Diseases Tags: Case Reports Source Type: research

Common symptoms for a rare disease in a girl with sarcoidosis: a case report
Sarcoidosis in pediatric age is uncommon and challenging diagnosis, because manifestations can be significantly variable and non-specific since it is a multisystem disease, and virtually any organ system may b...
Source: Italian Journal of Pediatrics - June 28, 2018 Category: Pediatrics Authors: Mattia Giovannini, Michele Luzzati, Giovanna Ferrara, Anna Maria Buccoliero, Gabriele Simonini, Maurizio de Martino, Rolando Cimaz and Teresa Giani Tags: Case report Source Type: research

Sarcoidosis onset simulating a unique hepatic metastasis.
We present a clinical case of a female diagnosed with an isolated hepatic sarcoidosis that simulated a unique hepatic metastatic lesion. The hepatic biopsy was diagnostic. PMID: 29931995 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - June 23, 2018 Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research

Clinical and biochemical presentation of sarcoidosis with high and normal serum angiotensin-converting enzyme.
CONCLUSION: Our study demonstrates that serum ionized calcium is significantly higher in the high sACE group but there was no statistical correlation to sACE. No other clinical or biochemical differences were observed. PMID: 29929412 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Rheumatology - June 22, 2018 Category: Rheumatology Authors: Sejdic A, Graudal N, Baslund B Tags: Scand J Rheumatol Source Type: research

Thoracic and cutaneous sarcoid-like reaction associated with anti-PD-1 therapy: longitudinal monitoring of PD-1 and PD-L1 expression after stopping treatment
ConclusionThis case sheds the light on a complex regulation of PD-L1 expression in vivo on PBMC after nivolumab arrest and triggers the question of monitoring the expression of immune checkpoint on immune cells during and after treatment with ICI.
Source: Journal for Immunotherapy of Cancer - June 13, 2018 Category: Cancer & Oncology Source Type: research

Identify sarcoid-like reaction in cancer patients receiving chemotherapy and immunotherapy: dont get into the weeds of SUVmax
Conclusions: To avoid pitfall in PET/CT interpretation, it is important to recognize the sarcoid-like pattern of FDG uptake, which regardless of SUV value is favored to represent a benign rather than a malignant process.
Source: Journal of Nuclear Medicine - May 23, 2018 Category: Nuclear Medicine Authors: Lu, Y., Macapinlac, H. Tags: Educational Exhibits Source Type: research

SUV-based analysis of Metabolic Priming of Myocardium for improved Diagnosis of Cardiac Sarcoidosis using 18F-FDG PET
Conclusion: These metrics can prove to be a useful part of the visual criteria for satisfactory quality assurance in cardiac FDG PET imaging for the purposes of sarcoidosis assessment.
Source: Journal of Nuclear Medicine - May 23, 2018 Category: Nuclear Medicine Authors: Mohiuddin, S., Ezuddin, S., Foley, M., Sfakianaki, E., Cassuto, J., Otero Cure, J., Kuker, R., Zhu, H., Serafini, A., Georgiou, M. Tags: Educational Exhibits Source Type: research

Utility of N-13 Ammonia and F-18 Fluorodeoxyglucose Cardiac Positron Emission Tomography in Assessing Regional Prevalence of Cardiac Sarcoidosis
Conclusion: This study shows a significant amount of cardiac sarcoidosis occurring in the basal region of the myocardium, specifically in the basal anterior and basal anteroseptal segments. This is valuable because most patients with CS present with complete heart block or ventricular arrhythmias, which originate from the basal anterior and basal septal regions. Understanding the regional distribution of CS may lead to better-informed prevention of these debilitating cardiac events.
Source: Journal of Nuclear Medicine - May 23, 2018 Category: Nuclear Medicine Authors: Lee, J., Flaherty, K., Cogan, J., Bokhari, N., Marshall, D., Jin, Z., Bokhari, S. Tags: Cardiovascular Clinical Science Poster Session Source Type: research