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Total 4942 results found since Jan 2013.

Diagnostic utility of endobronchial ultrasound features in differentiating malignant and benign lymph nodes.
Authors: Agrawal SP, Ish P, Goel AD, Gupta N, Chakrabarti S, Bhattacharya D, Sen MK, Suri JC Abstract Endobronchial ultrasound (EBUS) features have been shown to be useful in predicting etiology of enlarged malignant lymph nodes. However, there is dearth of evidence especially from developing countries. We assessed the EBUS characteristics across various mediastinal and hilar lymphadenopathies. In this prospective study, all patients with mediastinal and hilar lymphadenopathy on CT Chest and who were planned for EBUS-FNA (Fine Needle Aspiration) were included. EBUS features of lymph nodes studied were shape, size, ...
Source: Monaldi Archives for Chest Disease - June 29, 2018 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis
Respirology, EarlyView.
Source: Respirology - June 29, 2018 Category: Respiratory Medicine Authors: Amit Kishore , Zdenka Navratilova , Vitezslav Kolek , Eva Novosadova , Kl ára Čépe , Roland M. du Bois , Martin Petrek Source Type: research

Thoracic sarcoidosis versus tuberculosis: Need for a multi-disciplinary approach
Agrima Mian, Animesh RayIndian Journal of Radiology and Imaging 2018 28(2):267-268
Source: Indian Journal of Radiology and Imaging - June 28, 2018 Category: Radiology Authors: Agrima Mian Animesh Ray Source Type: research

Severe Myocardial Fibrosis After Sarcoid Inflammation
Publication date: July 2018 Source:Revista Española de Cardiología (English Edition), Volume 71, Issue 7 Author(s): Mario Sutil-Vega, Daniel Romeu Vilar, Eulàlia Roig
Source: Revista Espanola de Cardiologia - June 27, 2018 Category: Cardiology Source Type: research

Assessment of measurement methods of posterior inflammation in stromal choroiditis: the value of quantitative outcome measures versus the presently qualitatively based paradigm
ConclusionThis study highlights the precise measurement of global posterior inflammation achieved by a dual FA/ICGA scoring system in stromal choroiditis. In contrast, SUN-VH scale appears imprecise and inadequate, as only a minute percentage of the studied eyes could have been included in a clinical trial based on this criterion. To evaluate posterior intraocular inflammation meaningfully in stromal choroiditis, the use of dual FA/ICGA is strongly advised and should replace the presently recommended SUN-VH system.
Source: International Ophthalmology - June 26, 2018 Category: Opthalmology Source Type: research

Retinal vasculitis and systemic diseases.
Authors: Gascon P, Jarrot PA, Matonti F, Kaplanski G Abstract Retinal vasculitis (RV) is an inflammation of retinal blood vessels that can be associated with uveitis or be isolated, and can induce vascular occlusion and retinal ischemia. Visual acuity can be severely affected in case of macular involvement or neovessel formation. The diagnosis relies on fundoscopy and fluorescein angiography. Systemic diseases may be associated with RV, the most frequently encountered are Behçet's disease, sarcoidosis or multiple sclerosis, all predominantly associated with venous involvement, whereas systemic lupus erythematosus ...
Source: Revue de Medecine Interne - June 24, 2018 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

ASNC releases new guidelines for SPECT MPI
The American Society of Nuclear Cardiology (ASNC) has published its 2018 guidelines...Read more on AuntMinnie.comRelated Reading: SNMMI, ASNC offer guidelines for myocardial perfusion imaging with PET Radiologist wins ASNC's 1st clinical abstract award Medical societies expand collaboration on cardiac registry ASNC, SNMMI advise on cardiac sarcoidosis ASNC releases guidance on MPI in women
Source: AuntMinnie.com Headlines - June 21, 2018 Category: Radiology Source Type: news

Pulmonary haemodynamics and mortality in chronic hypersensitivity pneumonitis
Chronic hypersensitivity pneumonitis (CHP) is a common interstitial lung disease (ILD) frequently associated with lung fibrosis [1]. Among patients with CHP, the degree of pulmonary function impairment and the extent of fibrosis are known predictors of mortality [2, 3]. In other forms of ILD, such as idiopathic pulmonary fibrosis (IPF) and sarcoidosis, abnormal pulmonary haemodynamics measured during resting supine right heart catheterisation (RHC) are additionally associated with poor prognosis [4–7]. In CHP, however, the prognostic value of RHC is unknown.
Source: European Respiratory Journal - June 21, 2018 Category: Respiratory Medicine Authors: Oliveira, R. K. F., Ota-Arakaki, J. S., Gomes, P. S., Gimenez, A., Messina, C. M. S., Ramos, R. P., Ferreira, E. V. M., Systrom, D. M., Pereira, C. A. C. Tags: Original Articles: Research letters Source Type: research

Abdominal sarcoidosis presenting as bilateral simultaneous optic disc granulomas
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Source: Neuro-Ophthalmology - June 13, 2018 Category: Opthalmology Authors: Ayman G. Elnahry Gehad A. Elnahry Source Type: research

Chapter 21 Immune-mediated ataxias
Publication date: 2018 Source:Handbook of Clinical Neurology, Volume 155 Author(s): Bastien Joubert, Kevin Rostásy, Jérôme Honnorat Immune-mediated cerebellar ataxia (CA) comprises a group of rare diseases that are still incompletely described, and are probably underdiagnosed. Both acute and progressive progressions are possible. Different syndromes have been identified, including CA associated with anti-GAD antibodies, the cerebellar type of Hashimoto encephalopathy, primary autoimmune CA, gluten ataxia, opsoclonus-myoclonus syndrome, and paraneoplastic cerebellar degenerations. Most of these syndromes are associated ...
Source: Handbook of Clinical Neurology - June 13, 2018 Category: Neurology Source Type: research

Abdominal sarcoidosis presenting as bilateral simultaneous optic disc granulomas
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Source: Neuro-Ophthalmology - June 13, 2018 Category: Opthalmology Authors: Ayman G. Elnahry Gehad A. Elnahry Source Type: research

Assessment of posaconazole salvage therapy in chronic pulmonary aspergillosis using predefined response criteria
Chronic pulmonary aspergillosis (CPA) is a slowly progressive infection mainly caused by Aspergillus fumigatus, characterized by inflammatory destruction of lung tissue with cavitation, pleural thickening and/or fibrosis, and associated with significant respiratory and constitutional symptoms [1 –3]. CPA usually affects patients with underlying structural airway disease with air-filled cavities or bullae, such as tuberculosis (TB), non-tuberculous mycobacterial infection, chronic obstructive pulmonary disease (COPD), allergic bronchopulmonary aspergillosis (ABPA), pneumothorax and sarcoid osis.
Source: International Journal of Antimicrobial Agents - June 12, 2018 Category: Drugs & Pharmacology Authors: Isabel Rodriguez-Goncer, Chris Harris, Chris Kosmidis, Eavan G. Muldoon, Pippa J. Newton, David W. Denning Source Type: research

Assessment of posaconazole salvage therapy in chronic pulmonary aspergillosis by using predefined response criteria
Chronic pulmonary aspergillosis (CPA) is a slowly progressive infection mainly caused by Aspergillus fumigatus, characterized by inflammatory destruction of lung tissue with cavitation, pleural thickening and/or fibrosis, and associated with significant respiratory and constitutional symptoms [1 –3]. CPA usually affects patients with underlying structural airway disease with air-filled cavities or bullae, such as tuberculosis (TB), non-tuberculous mycobacterial infection, chronic obstructive pulmonary disease (COPD), allergic bronchopulmonary aspergillosis (ABPA), pneumothorax and sarcoid osis.
Source: International Journal of Antimicrobial Agents - June 12, 2018 Category: Drugs & Pharmacology Authors: Isabel Rodriguez-Goncer, Chris Harris, Chris Kosmidis, Eavan G. Muldoon, Pippa J. Newton, David W. Denning Source Type: research

Acute kidney injury as the presenting manifestation of sarcoidosis: A case series and review of literature
Nephrology,Volume 23, Issue 6, Page 597-600, June 2018.
Source: Nephrology - June 11, 2018 Category: Urology & Nephrology Authors: Theepika Rajkumar , Tom Lea ‐Henry , Bobby Chacko Source Type: research

Chapter 20 Differential diagnosis with other rapid progressive dementias in human prion diseases
Publication date: 2018 Source:Handbook of Clinical Neurology, Volume 153 Author(s): Michael D. Geschwind, Katy Murray Prion diseases are unique in medicine as in humans they occur in sporadic, genetic, and acquired forms. The most common human prion disease is sporadic Creutzfeldt–Jakob disease (CJD), which commonly presents as a rapidly progressive dementia (RPD) with behavioral, cerebellar, extrapyramidal, and some pyramidal features, with the median survival from symptom onset to death of just a few months. Because human prion diseases, as well as other RPDs, are relatively rare, they can be difficult to diagnose, as...
Source: Handbook of Clinical Neurology - June 8, 2018 Category: Neurology Source Type: research

Urinary N-terminal fragment of titin is a marker to diagnose muscular dystrophy in patients with cardiomyopathy
Publication date: September 2018 Source:Clinica Chimica Acta, Volume 484 Author(s): Akiomi Yoshihisa, Takatoyo Kiko, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Yasuchika Takeishi The differential diagnosis of cardiomyopathy is important. It has been recently reported that urinary titin N (U-TN) is increased in patients with muscular dystrophy (MD), and is associated with muscular damage. We aimed to clarify whether U-TN is useful as a diagnostic tool for distinguishing MD from various cardiomyopathies [e.g. dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM)]. We measured and compared the U-TN/creatin...
Source: Clinica Chimica Acta - June 7, 2018 Category: Laboratory Medicine Source Type: research

What rheumatologists can learn from ophthalmologists.
Abstract Intraocular inflammation with the imprecise and broad umbrella term "uveitis" is a diagnostic and therapeutic challenge in ophthalmology. Uveitis is one of the most common causes of blindness worldwide and due to the associated costs is comparable to diabetic retinopathy. Patients can be affected by uveitis at any age. Any part of the eye may be affected. The symptoms range from complete absence of symptoms, through all types of vision deterioration up to a red and even very painful eye. Uveitis can be strictly unilateral (also alternating from the left to the right eye) or bilateral with a relapsing o...
Source: Zeitschrift fur Rheumatologie - June 7, 2018 Category: Rheumatology Authors: Becker MD, Max R, Dimitriou A, Saurenmann T, Lorenz HM, Jansen A, Lortz S, Grulich-Henn J, Weber M Tags: Z Rheumatol Source Type: research

Muscular sarcoidosis under anti-TNF treatment in ankylosing spondylitis
Publication date: Available online 19 May 2018 Source:Joint Bone Spine Author(s): Daniel Wendling, Jean-Philippe Nueffer
Source: Joint Bone Spine - June 6, 2018 Category: Orthopaedics Source Type: research

Thyroid Gland < sup > 18 < /sup > F-FDG Uptake in Neurofibromatosis Type 1
Conclusion: Even though NF1 patients did not show an increased risk of thyroid incidentaloma on PET/CT compared to previous studies on non-thyroid cancer patients, the incidence shows that awareness of possible thyroid disease is important.Eur Thyroid J
Source: European Thyroid Journal - June 5, 2018 Category: Endocrinology Source Type: research

The Etiology of Intraocular Inflammation in HIV Positive and HIV Negative Adults at a Tertiary Hospital in Cape Town, South Africa.
CONCLUSION: Infectious uveitis is common in South Africa, especially amongst HIV+ patients. Causes of anterior and panuveitis differ between HIV+ and HIV- patients. PMID: 29847196 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - June 4, 2018 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

The Odd Gallbladder —a Rare Case of Gallbladder and Lymph Node Sarcoidosis: a Case Report and Review of the Literature
Source: Journal of Gastrointestinal Cancer - June 2, 2018 Category: Cancer & Oncology Source Type: research

Urinary N-terminal fragment of titin is a marker to diagnose muscular dystrophy in patients with cardiomyopathy.
Abstract The differential diagnosis of cardiomyopathy is important. It has been recently reported that urinary titin N (U-TN) is increased in patients with muscular dystrophy (MD), and is associated with muscular damage. We aimed to clarify whether U-TN is useful as a diagnostic tool for distinguishing MD from various cardiomyopathies [e.g. dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM)]. We measured and compared the U-TN/creatinine ratio (U-TN/Cr; pmol/mg/dl) in 278 control subjects and 331 patients with various cardiomyopathies (DCM, n = 199; sarcoidosis, n = 18; HCM, n = 86; amyloid...
Source: International Journal of Clinical Chemistry - June 2, 2018 Category: Chemistry Authors: Yoshihisa A, Kiko T, Sato T, Oikawa M, Kobayashi A, Takeishi Y Tags: Clin Chim Acta Source Type: research

Bilateral Cicatrizing Conjunctivitis in a Middle-aged Man
A 53-year-old man with multiorgan sarcoid presented with chronic ocular irritation and bilateral trichiasis of the lower eyelids with scarring of the inferior fornices and symplepharon, but no evidence of intraocular involvement of sarcoid. What would you do next?
Source: JAMA Ophthalmology - June 1, 2018 Category: Opthalmology Source Type: research

Tattoo ‐associated uveitis with or without systemic sarcoidosis: a comparative review of the literature
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Source: Journal of the European Academy of Dermatology and Venereology - May 29, 2018 Category: Dermatology Authors: N. Kluger Source Type: research

Sarcoidosis with multiple organ involvement
Clinical Case Reports, EarlyView.
Source: Clinical Case Reports - May 29, 2018 Category: General Medicine Authors: Yve Mendes Rodrigues , Gl áucia Zanetti , Edson Marchiori Source Type: research

Tattoo ‐associated uveitis with or without systemic sarcoidosis: a comparative review of the literature
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Source: Journal of the European Academy of Dermatology and Venereology - May 29, 2018 Category: Dermatology Authors: N. Kluger Source Type: research

Sarcoidosis: when the initial manifestations are musculoskeletal symptoms
Abstract The recent association between the increase in the number of neonates with microcephaly in northeastern Brazil and the outbreak of infection with the Zika virus, which has been occurring in the Americas, has been declared a public health emergency of international concern. The evidence that implicates the virus as the cause of this public health emergency has been demonstrated ever more consistently. This pictorial essay illustrates the imaging characteristics seen on computed tomography and magnetic resonance imaging scans of infants admitted to a rehabilitation hospital with a diagnosis of microcephaly and a mat...
Source: Radiologia Brasileira - May 28, 2018 Category: Radiology Source Type: research

Electrocardiogram and Imaging
This article focuses on the role of echocardiography and MRI in the diagnosis of these structural diseases. Cardiomyopathies with hypertrophic pattern (hypertrophic cardiomyopathy, restrictive cardiomyopathies, amyloidosis, Anderson-Fabry disease, and sarcoidosis), cardiomyopathies with dilated pattern, inflammatory cardiac diseases, and right ventricular arrhythmogenic cardiomyopathy are analyzed. Finally, anatomic predictors of arrhythmias and sudden cardiac death are discussed. Each paragraph is attended by clinical cases that are discussed on the electrocardiogram, after integrated with the anatomic, functional, and he...
Source: Cardiac Electrophysiology Clinics - May 24, 2018 Category: Cardiology Source Type: research

Coexisting Systemic Sclerosis-Polymyositis and Sarcoidosis: Case Report and Review of the Literature
No abstract available
Source: JCR: Journal of Clinical Rheumatology - May 23, 2018 Category: Rheumatology Tags: Letters to the Editor Source Type: research

Hepatic infectious and inflammatory conditions: Role of 18F-FDG PET imaging with multimodality correlation and implications for management
Conclusion: Molecular imaging with FDG PET is traditionally thought of as a tool for management of malignant conditions. However it can be used in demonstrating and managing hepatic infectious and inflammatory conditions. Awareness of multimodality imaging features of some of these common conditions will help in their accurate diagnosis and appropriate management.
Source: Journal of Nuclear Medicine - May 23, 2018 Category: Nuclear Medicine Authors: Garg, I., baladron, M., Samreen, N., Johnson, G., Goenka, A., Venkatesh, S., Kendi, A. Tags: Educational Exhibits Source Type: research

Erratum.
Authors: Tchernev G, Chikoeva AA, Tana M, Tana C Abstract In the article "Transcriptional blood signatures of sarcoidosis, sarcoid-like reactions and tubercolosis and their diagnostic implications" which appeared in Volume 33, Issue 3 (2016) of Sarcoidosis, vasculitis and diffuse lung diseases, the title was given incorrectly. The correct title is "Transcriptional blood signatures of sarcoidosis, sarcoid-like reactions and tuberculosis and their diagnostic implications". PMID: 28079860 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - January 14, 2017 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Acute sarcoid myopathy: a case report and literature review.
We present a case of a 61-year-old man with diagnosis of sarcoidosis whe were evaluated for proximal lower limb weakness within few days of evolution. PMID: 28079855 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - January 14, 2017 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Vitamin D deficiency and activity of sarcoidosis
Conclusion: Patients with hypercalciuria have active disease; it is shown that the active form of the disease is associated with low values of vitamin 25(OH)D in the serum.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Filipovic, S., Violeta, V., Jelica, V., Mihailo, S., Aleksandar, J. Tags: 1.5 Diffuse Parenchymal Lung Disease Source Type: research

Endobronchial ultrasound (EBUS) transbronchial needle aspiration (TBNA) in germ cell cancer patients with mediastinal lymphadenopathy: A single centre retrospective analysis
Conclusion: Our retrospective analysis demonstrated the coincidence of GCC and SLL to be a frequent finding. EBUS-TBNA is a safe diagnostic approach to confirm SLL. Therefore, aggressive diagnostic approaches such as mediastinoscopy can be avoided. Still, both the prognostic and the immunologic impact of SLL in GCC remain unclear. Further studies should investigate the underlying biological mechanisms and the impact on prognosis.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Schmidt, L., Lauterbach, B., Hansmeier, A., Hartig, I., Kessler, T., Schliemann, C., Schulze, A. B., Wardelmann, E., Pühse, G., Berdel, W., Wiewrodt, R., Mohr, M. Tags: 1.4 Interventional Pulmonology Source Type: research

Transcriptional blood signatures of sarcoidosis, sarcoid-like reactions and tubercolosis and their diagnostic implications.
Authors: Tchernev G, Chokoeva AA, Tana M, Tana C Abstract N/A. PMID: 27759000 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 21, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Subacute sarcoid myositis with ocular muscle involvement; a case report and review of the literature.
We describe a case of acute to subacute sarcoid myositis of the skeletal and extraocular muscles. Typical ophthalmic involvement (manifested by infiltration of the ocular adnexa, intraocular inflammation, or infiltration of the retrobulbar visual pathways) and extraocular sarcoid myositis (as with the present case) is infrequently reported. It is important to keep in mind the rare yet perhaps underestimated entity of sarcoid myositis, and to utilize muscle biopsy and imaging tests for appropriate diagnosis and management of patients with sarcoidosis. PMID: 27758998 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 21, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Pulmonary stenting for the treatment of sarcoid induced pulmonary vascular stenosis.
CONCLUSIONS: Pulmonary vascular stenosis from external compression can be a rare but unrecognized caused of worsening symptoms in advanced sarcoidosis. Pulmonary vascular angioplasty and stenting can provide clinical benefit in select patients. PMID: 27758995 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 21, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Extensive pulmonary sarcoid reaction in a patient with BMPR-2 associated idiopathic pulmonary arterial hypertension.
We describe a case of a 35-year-old woman with idiopathic pulmonary arterial hypertension (IPAH) and a novel BMPR2 mutation, who underwent a successful lung transplantation.  Extensive granulomatous inflammation was seen in the resected lungs. The granulomatous inflammation found in the histology supports  a sarcoid-like reaction due to pulmonary hypertension in the context of the BMPR2 mutation. PMID: 27537724 [PubMed - as supplied by publisher]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - August 19, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Pulmonary metastases from low grade sarcoma in a patient with pulmonary sarcoidosis. Sarcoidosis or sarcoid-like reaction?
Authors: Majori M, Anghinolfi M, Gnetti L, Casalini AG Abstract An asymptomatic man with previous histopatological diagnosis of pulmonary sarcoidosis in radiological follow-up (stable for about 4 years) presented massive right pleural effusion. After drainage, CT of the chest showed an increase in number and size of pulmonary nodules compared to the last check (8 months before). Surgical pulmonary biopsies were performed with the diagnosis of metastases from low grade sarcoma. The primary tumor was localized to the right buttock. Given the absence of symptoms, the extent of disease and many comorbidities the patien...
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - August 19, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Papular sarcoidosis of the knees. A frequent form of presentation of systemic sarcoidosis.
CONCLUSION: Papular sarcoidosis of the knees can be considered a relatively frequent form of cutaneous sarcoidosis usually present at the beginning of the disease that can be useful for the diagnosis of sarcoidosis. It is mainly observed in acute forms of sarcoidosis and can be considered a sign of good prognosis. PMID: 27055837 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 9, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Lung transplantation for pulmonary sarcoidosis. Twenty-five years of experience in the USA
Conclusions Recipients of lung transplants for pulmonary sarcoidosis had similar outcomes compared with non-sarcoid lung recipients.
Source: Thorax - March 14, 2016 Category: Respiratory Medicine Authors: Taimeh, Z., Hertz, M. I., Shumway, S., Pritzker, M. Tags: Epidemiologic studies, Interstitial lung disease, Cardiothoracic surgery, Transplantation Research letter Source Type: research

Propionibacterium acnes isolated from lymph nodes of patients with sarcoidosis.
We report two non-Japanese patients in whom mediastinoscopy was performed in order to obtain lymph node tissue for histopathology, which was suggestive for sarcoidosis. Bacterial culture of these uncontaminated mediastinal lymph nodes revealed P. acnes in both patients. As shown in these two cases, P. acnes can be isolated from sterile biopsied sarcoid lymph nodes of non-Japanese patients and supports the belief that there is an etiologic link between P. acnes sarcoidosis. Further elucidation could provide an opening to novel strategies using antibiotics for treating sarcoidosis. PMID: 26422574 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 3, 2015 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Sarcoid in cancer patients: clinical characteristics and associated disease status.
CONCLUSION:   While sarcoid often presents at initial diagnosis or staging of cancer, in a significant number of patients, it appears in association with recurrence or second malignancy. PMID: 26422564 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 3, 2015 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Cigarette smoking and male sex are independent and age concomitant risk factors for the development of ocular sarcoidosis in a New Orleans sarcoidosis population.
CONCLUSION: To date, there are few dedicated investigations of risk factors for OS, especially smoking. This investigation identified male sex, age, and tobacco exposure as independent risk factors for OS. Though disease duration did not withstand regression analysis in this moderately sized group, age at chart review suggests screening for OS should not remit but rather intensify in aging patients with sarcoidosis. (Sarcoidosis Vasc Diffuse Lung Dis 2015; 32: 183-143). PMID: 26278693 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - August 19, 2015 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Evaluation of Mediastinal Lymph Nodes in Sarcoidosis, Sarcoid Reaction, and Malignant Lymph Nodes Using CT and FDG-PET/CT
Abstract: The aim of this study was to analyze the clinical, computed tomography (CT), and positron emission tomography (PET) findings of sarcoidosis, sarcoid reaction, and malignant lymph nodes (LNs) to the results of transbronchial LN aspiration and biopsy (TBNA). The TBNA results of mediastinal and hilar LNs of 152 patients in our hospital from July 2008 to March 2013 were retrospectively reviewed. Two independent radiologists measured the size and attenuation of LNs on CT and assessed the probability of the 3 categories: sarcoidosis (n = 36), sarcoid reaction (n = 25), or malignant LNs (n = 91). The total v...
Source: Medicine - July 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Thyroid cancer & sarcoidosis.
CONCLUSION: Clinicians should be wary of this association/co-existence of SA and PTC to avoid mismanagement of neck lymphadenopathies in patients with current or history of SA. Although 4% of thyroid cancers may induce a sarcoid reaction in the thyroid gland, SA as a disease may coexist with PTC although causality remains uncertain. Being aware of this association is important in the differential diagnosis of a thyroid mass and/or a LN in a patient with SA. Therefore, patients with known SA who are found to have cervical adenopathies or thyroid nodules should have a thorough work up. PMID: 25363225 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - November 25, 2014 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Anxiety, its relation to symptoms severity and anxiety sensitivity in sarcoidosis.
Conclusions: These data confirmed earlier reports that anxiety and depression are common in patients with sarcoidosis and expanded on the previous results by showing that patients exhibited increased anxiety sensitivity and a fear of physical sensations. These results, together with the findings that anxiety was associated with sarcoidosis symptom severity, suggest that targeting anxiety and the physical health concerns may be important in the diagnosis and management of this disease. PMID: 24351619 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - November 25, 2014 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Recurrence of sarcoid granulomas in lung transplant recipients is common and does not affect overall survival.
Conclusions: Approximately 30% of lung transplant recipients due to sarcoidosis have recurrence of sarcoid granulomas. Recurrence of granulomas does not affect overall survival or lung function. PMID: 25078643 [PubMed - as supplied by publisher]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - November 25, 2014 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Sarcoidosis on tattoos: a review of the literature from 1939 to 2011.
Authors: Kluger N Abstract Sarcoidosis is an autoimmune disease of unknown etiology characterized by the presence of non-caseating epithelioid cell granulomas in multiple organs. Cutaneous sarcoidosis occurs in approximately 25% of the cases. Sarcoid reactions on old scars, traumatized skin sites and around embedded foreign material have long been observed. For the past 70 years, sarcoidal granulomas on tattoos and permanent make-up have also been documented. Granulomatous and sarcoidal tattoo reactions may be the first and sometimes only cutaneous manifestation of systemic sarcoidosis. This review summarizes the c...
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - November 25, 2014 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Sarcoidosis or sarcoid-like reaction developed during the follow-up of malignant tumors: difficulties in differentiation from recurrent or metastatic diseases
Abstract Sarcoidosis or sarcoid-like reaction can occur or manifest several years after completion of treatment during the long-term follow-up of malignant tumors, often creating difficulty in differentiating these lesions from recurrent or metastatic malignant tumors on imaging studies. In recent years, CT and positron-emission tomography (PET) have been widely used in follow-up of malignant tumors; and findings in these studies are similar for sarcoidosis/sarcoid-like reaction and recurrent/metastatic diseases, special caution is needed in diagnosing either of these disorders. In patients who show results i...
Source: International Cancer Conference Journal - October 1, 2014 Category: Cancer & Oncology Source Type: research