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Total 5528 results found since Jan 2013.

Exercise ‐related sudden cardiac death of an American football player with arrhythmogenic right ventricular dysplasia/cardiomyopathy AND sarcoidosis
This case emphasizes the value of cardiac MRI and genetic testing in the early phase of ARVD/C. It also emphasizes the increased risk of SCD for patients with ARVD/C participating in competitive sports, even with immediate cardiopulmonary resuscitation. Key Clinical MessageThis case emphasizes the value of cardiac MRI and genetic testing in the early phase of ARVD/C. It also emphasizes the increased risk of SCD for patients with ARVD/C participating in competitive sports, even with immediate cardiopulmonary resuscitation.
Source: Clinical Case Reports - February 19, 2019 Category: General Medicine Authors: Andreas M üssigbrodt, Helge Knopp, Csilla Czimbalmos, Cosima Jahnke, Sergio Richter, Daniela Husser, Tanja Gradistanac, Gerhard Hindricks Tags: CASE REPORT Source Type: research

Diagnostic performance of F 18 FDG PET in cardiac sarcoidosis: Are we getting closer to the truth?
Source: Journal of Nuclear Cardiology - February 15, 2019 Category: Nuclear Medicine Source Type: research

Imaging cardiac sarcoidosis with FDG-PET: Take a look at the right side!
Source: Journal of Nuclear Cardiology - February 15, 2019 Category: Nuclear Medicine Source Type: research

What is PET/MRI's value for cardiac sarcoidosis?
Much has been researched and written about the promise of PET/MRI. While the...Read more on AuntMinnie.comRelated Reading: Ga-68 PSMA-11 PET/MRI benefits prostate cancer patients TOF PET/MRI makes dose reduction viable for breast cancer How effective is PET/MRI for rectal cancer? PET/MRI with ferumoxytol MR contrast performs well for pediatric patients Cardiac FDG-PET/MRI's role in Anderson-Fabry disease
Source: AuntMinnie.com Headlines - February 12, 2019 Category: Radiology Source Type: news

64-Year-Old Man With Subacute Altered Mental Status and Headache
A 64-year-old man from Iowa with a medical history of sarcoidosis, managed with prednisone, 20 mg/d, for the past 5 months, presented to the emergency department with gradual-onset, progressive altered mental status and headaches of 1 month ’s duration. Previously, he was cognitively intact according to his daughter. He had become unable to perform normal daily tasks such as unlocking doors and holding normal conversations. Additionally, he reported a generalized, throbbing, constant headache associated with intermittent blurry visio n.
Source: Mayo Clinic Proceedings - February 12, 2019 Category: Internal Medicine Authors: Nandini S. Mehra, Robert C. Ward, Meltiady Issa Tags: Residents ’ clinic Source Type: research

Using FDG-PET to guide targeted cardiac magnetic resonance imaging in patients with suspected cardiac sarcoidosis
Source: Journal of Nuclear Cardiology - February 8, 2019 Category: Nuclear Medicine Source Type: research

Focal Myositis of the Leg Presenting as Fever of Unknown Origin Detected by FDG PET/CT
We present one case of focal myositis involving the left proximal vastus lateralis and vastus intermedius, and left soleus showing intense FDG uptake on FDG PET/CT. This case indicates that focal myositis should be considered as a differential diagnosis in patients with focal hypermetabolic muscular lesions, including benign and malignant tumors, necrotizing autoimmune myopathy, nodular fasciitis, myositis ossificans, and muscular sarcoidosis.
Source: Clinical Nuclear Medicine - February 7, 2019 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Hypertrophic cervical spine pachymeningitis due to sarcoidosis: a case report
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Source: Hospital Practice - February 6, 2019 Category: Hospital Management Authors: Hussam A. Yacoub P. Mark Li Joshua A. Bemporad Dmitry Khaitov Daniel F. Brown Source Type: research

Takayasu's Arteritis and Sarcoidosis in the Era of Advanced Molecular Imaging
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Source: Arthritis and Rheumatology - February 4, 2019 Category: Rheumatology Authors: Blas Y. Betancourt, Mark A. Ahlman, Peter C. Grayson Tags: Clinical Image Source Type: research

Multiple Sclerosis and Autoimmune Neurology of the Central Nervous System.
Abstract Autoimmune disorders of the central nervous system are common and often affect people in the most productive years of their lives. Among primary autoimmune diseases of the central nervous system, multiple sclerosis is most prevalent in the United States. Many other autoantibody-mediated neurologic syndromes have been identified within the past 2 to 3 decades, including neuromyelitis optica and anti-N-methyl-D aspartate receptor encephalitis. Finally, the central nervous system can also be affected by systemic autoimmune diseases such as sarcoidosis. Many of these diseases are treatable when detected early...
Source: The Medical Clinics of North America - February 3, 2019 Category: General Medicine Authors: Galetta KM, Bhattacharyya S Tags: Med Clin North Am Source Type: research

Science Saturday: A hard look at a devastating heart disease
Though rare, cardiac sarcoidosis is a condition that can wreak havoc on the heart. It can be triggered by environmental or infectious agents and is characterized by an overactive immune response, involving clusters of white blood cells that aggregate in heart tissue. Those clusters can result in the need for a pacemaker, and may even [...]
Source: News from Mayo Clinic - February 2, 2019 Category: Databases & Libraries Source Type: news

Role of 18F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring: Addition to the Expert Consensus
Source: Journal of Nuclear Medicine - February 1, 2019 Category: Nuclear Medicine Authors: Lu, Y., Sweiss, N. J. Tags: Letters Source Type: research

Reply: Role of 18F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring: Addition to the Expert Consensus
Source: Journal of Nuclear Medicine - February 1, 2019 Category: Nuclear Medicine Authors: Chareonthaitawee, P., Blankstein, R. Tags: Letters Source Type: research

Diagnosis and differential diagnosis of large-vessel vasculitides
AbstractThere are no universally accepted diagnostic criteria for large-vessel vasculitides (LVV), including giant cell arteritis (GCA) and Takayasu arteritis (TAK). Currently, available classification criteria cannot be used for the diagnosis of GCA and TAK. Early diagnosis of these two diseases is quite challenging in clinical practice and may be accomplished only by combining the patient symptoms, physical examination findings, blood test results, imaging findings, and biopsy results, if available. Awareness of red flags which lead the clinician to investigate TAK in a young patient with persistent systemic inflammation...
Source: Rheumatology International - February 1, 2019 Category: Rheumatology Source Type: research

Evaluation of MyoStrain ™ in Clinical Practice
Conditions:   Cardiac Failure;   Coronary Artery Disease;   Sarcoidosis;   Amyloidosis;   Lupus;   Myocarditis;   Drug Toxicity Intervention:   Procedure: Diagnostic Test: Myostrain Sponsor:   University of Kansas Medical Center Not yet recruiting
Source: ClinicalTrials.gov - January 31, 2019 Category: Research Source Type: clinical trials

Neurosarcoidosis Occurring 6 Years after Onset of Vogt-Koyanagi-Harada Disease
We report a case of the concurrence of VKHD and sarcoidosis, which may share a common pathophysiology. Accumulation of further similar cases is necessary to elucidate the precise mechanism underlying the concurrence of these two diseases.Case Rep Ophthalmol 2019;10:32 –40
Source: Case Reports in Ophthalmology - January 27, 2019 Category: Opthalmology Source Type: research

Odontoid cervical gout causing atlantoaxial instability: case report.
Abstract The authors present a case report of a patient discovered to have a rotatory subluxation of the C1-2 joint and a large retroodontoid pannus with an enhancing lesion in the odontoid process eventually proving to be caused by gout. This patient represented a diagnostic conundrum as she had known prior diagnoses of not only gout but also sarcoidosis and possible rheumatoid arthritis, and was in the demographic range where concern for an oncological process cannot fully be ruled out. Because she presented with signs and symptoms of atlantoaxial instability, she required posterior stabilization to reduce the r...
Source: Journal of Neurosurgery.Spine - January 25, 2019 Category: Neurosurgery Authors: Slavin J, DiStasio M, Dellaripa PF, Groff M Tags: J Neurosurg Spine Source Type: research

Multiple huge “cluster” and “galaxy” signs on chest radiography in a patient with pulmonary tuberculosis
In this article, we present a unique case of active pulmonary tuberculosis, with multiple huge “cluster” signs like fireworks, together with multiple “galaxy” signs. The repeated acid‐fast sputum smears and both bronchial washings were all negative forMycobacterium tuberculosis, but the acid ‐fast culture of sputum taken soon after the first bronchoscopy, and pleural fluid, turned out to be positive forM. tuberculosis at six weeks after admission. The present case clearly demonstrates that the “galaxy” and “cluster” signs are red herring signs of the low rates of isolatingM. tuberculosis, which should b...
Source: Respirology Case Reports - January 25, 2019 Category: Respiratory Medicine Authors: Miku Oda, Takeshi Saraya, Tatsuya Shirai, Narishige Ishikawa, Masachika Fujiwara, Hajime Takizawa Tags: Case Report Source Type: research

Tofacitinib Hypothesis-generating, Pilot Study for Corticosteroid-Dependent Sarcoidosis
Conditions:   Sarcoidosis, Pulmonary;   Sarcoidosis Lung;   Sarcoidosis Interventions:   Drug: Tofacitinib 5mg Oral Tablet [Xeljanz] 16 week trial;   Diagnostic Test: Spirometry;   Genetic: RNA Sequencing;   Diagnostic Test: Laboratory testing;   Drug: Corticosteroid;   Drug: Tofacitinib 5mg [Xeljanz] 1 year open-label extension Sponsors:   Oregon Health and Science University;   Pfizer Not yet recruiting
Source: ClinicalTrials.gov - January 4, 2019 Category: Research Source Type: clinical trials

18 F-FDG uptake of the right ventricle is an important predictor of histopathologic diagnosis by endomyocardial biopsy in patients with cardiac sarcoidosis
ConclusionsFDG uptake of the RV but no other heart segment was associated with positive EMB in CS patients. The presence of RV FDG uptake could improve the rate of positive EMB up to 42% in patients with CS.
Source: Journal of Nuclear Cardiology - January 4, 2019 Category: Nuclear Medicine Source Type: research

Diagnostic performance of F-18 FDG PET for detection of cardiac sarcoidosis; A systematic review and meta-analysis
ConclusionThe current meta-analysis showed the moderate sensitivity and specificity of F-18 FDG PET or PET/CT for diagnosis of CS. The presence of combined myocardial perfusion imaging could improve diagnostic accuracy of F-18 FDG PET or PET/CT for diagnosis of CS. At present, the literature regarding the use of F-18 FDG PET for detection of CS remains limited; thus, further large multicenter studies would be necessary to substantiate the diagnostic accuracy of F-18 FDG PET for diagnosis of CS.
Source: Journal of Nuclear Cardiology - January 2, 2019 Category: Nuclear Medicine Source Type: research

Same day comparison of PET/CT and PET/MR in patients with cardiac sarcoidosis
ConclusionIn this limited patient study, PET/CT and PET/MR provided similar diagnostic data for18F-FDG uptake, and the concurrent acquisition of MR images provided further insight into the disease process.
Source: Journal of Nuclear Cardiology - January 2, 2019 Category: Nuclear Medicine Source Type: research

Dacryocystitis and Rhinosinusitis Secondary to Sarcoidosis
Sarcoidosis rarely develops in the lacrimal sac. Lacrimal sac sarcoidosis may be associated with sarcoidosis-related rhinosinusitis. The anatomical and histological relationship between the lacrimal drainage system and nasal mucosa has been indicated as a predisposing factor for this concomitance. However, the characteristics of this condition are not fully understood. Herein, the authors report a case where dacryocystitis and rhinosinusitis developed secondary to sarcoidosis. Pathological examination of the lacrimal sac wall revealed noncaseating epithelioid granulomas in the subepithelial layer, which contains the lacrim...
Source: Journal of Craniofacial Surgery - January 1, 2019 Category: Surgery Tags: Brief Clinical Studies Source Type: research

Woman's Case Gives Hope Against Sarcoidosis
Sarcoidosis is an inflammatory disease that affects multiple organs. While some patients recover without treatment, others suffer damage to lungs, heart, lymph nodes, skin and other organs. On the skin, it can cause disfiguring lesions.
Source: WebMD Health - December 26, 2018 Category: Consumer Health News Source Type: news

Yale experts treat severe, disfiguring sarcoidosis with novel therapy
A team of Yale researchers has found a promising new treatment for sarcoidosis, a disease that can affect multiple organs: tofacitinib, an arthritis medication.
Source: Yale Science and Health News - December 26, 2018 Category: Universities & Medical Training Source Type: news

One Woman ' s Case Gives New Hope Against Disfiguring Sarcoidosis
WEDNESDAY, Dec. 26, 2018 -- In very preliminary findings, an existing rheumatoid arthritis drug appeared to cure one woman of a rare but potentially life-threatening condition known as sarcoidosis. After 10 months of use, tofacitinib (Xeljanz)...
Source: Drugs.com - Daily MedNews - December 26, 2018 Category: General Medicine Source Type: news

Yale experts treat severe, disfiguring sarcoidosis with novel therapy
(Yale University) An all-Yale team of researchers successfully treated a patient with disfiguring sarcoidosis, a chronic disease that can affect multiple organs, with a drug approved for rheumatoid arthritis. Successful treatment of two other patients with similarly severe disease suggests an effective treatment for an incurable, sometimes life-threatening illness is within reach, the scientists said.
Source: EurekAlert! - Medicine and Health - December 26, 2018 Category: International Medicine & Public Health Source Type: news