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Total 4711 results found since Jan 2013.

18F-FDG PET/CT helps in unmasking the great mimicker: A case of neurosarcoidosis with isolated involvement of the spinal cord
Publication date: May–June 2018 Source:Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), Volume 37, Issue 3 Author(s): A. Gholamrezanezhad, L. Mehta A 36 year-old male with no significant past medical history presented with lower extremity numbness, gait instability, and urinary and bowel retention of 4 weeks onset. Spine MRI revealed diffuse oedema of cervicothoracic spinal cord with several solid enhancing intramedullary lesions, suggestive of metastases. The 18F-FDG PET/CT performed to identify the primary malignancy demonstrated mild hypermetabolic foci within the cervicothoracic cord, as w...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - May 3, 2018 Category: Nuclear Medicine Source Type: research

Ipilimumab-Induced Sarcoidosis and Thyroiditis
No abstract available
Source: American Journal of Therapeutics - May 1, 2018 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research

A cavernous sinus lesion clinically responsive to steroids
We describe a patient presenting with neurologic symptoms referable to a persistent unilateral cavernous sinus MRI abnormality, initially thought to be consistent with Tolosa-Hunt syndrome, that was clinically but not radiographically responsive to steroids. Following reevaluation due to the presence of new symptoms, pathology revealed that the abnormality was most consistent with chordoma, a rare skull based tumor. In patients with a presumed diagnosis of Tolosa-Hunt syndrome, close clinical and radiographic follow-up is imperative, with early consideration for biopsy in patients that fail to respond to treatment both cli...
Source: Journal of Clinical Neuroscience - May 1, 2018 Category: Neuroscience Source Type: research

What Causes Flushing?
Discussion Flushing is usually thought of as a benign condition such as blushing, but can be quite irritating if it is frequent or persistent (i.e. menopausal hot flashes) or even pathologic (i.e. malignancy). “Flushing is a subjective and sensation of warmth that is accompanied by reddening of the skin anywhere on the body but favors the face, neck, and upper torso…. Flushing can be broadly divided into episodic or persistent. Episodic flashing is mediated by the release of endogenous vasoactive mediators or medications, while persistent flushing result in a fixed facial erythema with telangiectasias and cyano...
Source: PediatricEducation.org - April 30, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

941 Molecular, physiological, and pathological backgrounds of recently proposed three subspecies of Propionibacterium acnes
Propionibacterium acnes (Cutibacterium acnes) is a predominating bacterial species on the human skin, which is considered to have a role in developing acne vulgaris, SAPHO syndrome, sarcoidosis, and various deep tissue infections. Very recently, the three types of the species are given the official recognition as three distinct subspecies ( Dekio et al. 2015 McDowell et al. 2016 ). This status is a triumph of the continuous research into the nature of these types since they were coined decades ago.
Source: Journal of Investigative Dermatology - April 27, 2018 Category: Dermatology Authors: I. Dekio, M. Sakamoto, Y. Murakami, M. Ohkuma Tags: Innate Immunity, Microbiology, Inflammation Source Type: research

Value of 18-F-FDG PET/CT in assessment of patients with fever of unknown origin
Conclusion 18F-FDG PET/CT can be a useful tool for scanning the whole body to suggest the FUO cause.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - April 27, 2018 Category: Nuclear Medicine Source Type: research

Ex-vivo Production of Regulatory B-Cells for Use in Auto-immune Diseases
Regulatory B-cells (Breg) play an important role in reducing autoimmunity and reduced levels of these cells are implicated in etiology of several auto-inflammatory diseases. Despite their impact in many diseases, their physiological inducers are unknown.   Given that Bregs are a very rare B-cell, identifying factors that promote their development would allow in vivo modulation of Breg levels and ex-vivo production of large amounts of antigen-specific Bregs to use in immunotherapy for auto-inflammatory diseases.  Researchers at NEI ' sMolecular Immunology Section developed a method for theex-vivo production of Breg. The ...
Source: NIH OTT Licensing Opportunities - April 26, 2018 Category: Research Authors: ajoyprabhu3 Source Type: research

Heart Transplantation for End Stage Cardiac Sarcoidosis: Increasingly Used with Excellent Results
Publication date: Available online 25 April 2018 Source:Canadian Journal of Cardiology Author(s): Mustafa Toma, David Birnie
Source: Canadian Journal of Cardiology - April 26, 2018 Category: Cardiology Source Type: research

Sarcoidosis Related Novel Candidate Genes Identified by Multi-Omics Integrative Analyses
OMICS: A Journal of Integrative Biology, Ahead of Print.
Source: OMICS: A Journal of Integrative Biology - April 24, 2018 Category: Biology Authors: Keli Ho čevar Ale š Maver Tanja Kunej Borut Peterlin Source Type: research

Unexplained cough: it is time to rule out Sjogren ’s syndrome
We describe patients in whom unexplained chronic cough was associated with dry eyes. Focused workup revealed undiagnosed Sjogren’s syndrome in 36%. Dry eyes, with or without SS, is under-recognized and should be added to diagnostic algorithms for unexplained cough.
Source: Clinical Rheumatology - April 23, 2018 Category: Rheumatology Source Type: research

Cardiac Positron Emission Tomography-Magnetic Resonance Imaging: Current Status and Future Directions
Simultaneous acquisition positron emission tomography-magnetic resonance imaging (PET-MRI) has the ability to combine anatomic information derived from cardiac MRI with quantitative capabilities of cardiac PET and MRI and the promise of molecular imaging by specific PET tracers. This combination of cardiac PET and MRI delivers a robust and comprehensive clinical examination. It has the potential to assess various cardiovascular conditions, including assessment of myocardial ischemia, infarction, and function, as well as specific characterization of inflammatory and infiltrative heart diseases such as cardiac sarcoid and am...
Source: Journal of Thoracic Imaging - April 20, 2018 Category: Radiology Tags: Review Articles Source Type: research

941 Molecular, physiological, and pathological backgrounds of recently proposed three subspecies of Propionibacterium acnes
Propionibacterium acnes (Cutibacterium acnes) is a predominating bacterial species on the human skin, which is considered to have a role in developing acne vulgaris, SAPHO syndrome, sarcoidosis, and various deep tissue infections. Very recently, the three types of the species are given the official recognition as three distinct subspecies ( Dekio et al. 2015 McDowell et al. 2016 ). This status is a triumph of the continuous research into the nature of these types since they were coined decades ago.
Source: Journal of Investigative Dermatology - April 19, 2018 Category: Dermatology Authors: I. Dekio, M. Sakamoto, Y. Murakami, M. Ohkuma Tags: Innate Immunity, Microbiology, Inflammation Source Type: research

An atypical case of neurosarcoidosis presenting with neovascular glaucoma
ConclusionsA patient with neurosarcoidosis presenting with compressive ischemic optic disc edema and neovascular glaucoma is described, increasing the diversity of clinical presentations and confirming the diagnostic challenge of neurosarcoidosis.
Source: Journal of Ophthalmic Inflammation and Infection - April 18, 2018 Category: Opthalmology Source Type: research

Secondary calcification associated with subcutaneous sarcoidosis
The Journal of Dermatology, EarlyView.
Source: The Journal of Dermatology - April 18, 2018 Category: Dermatology Authors: Tatsuhiko Mori , Toshiyuki Yamamoto Source Type: research

Dermatologic toxicities of immune checkpoint inhibitors.
Abstract The development of immune checkpoint inhibitors (monoclonal antibodies targeting PD-1/PD-L1 or CTLA-4) represents a significant advance in the treatment of multiple cancers. Given their particular mechanism of action, which involves triggering CD4+/CD8+ T-cell activation and proliferation, they are associated with a specific safety profile. Their adverse events are primarily immune-related, and can affect practically all organs. In this context, dermatological toxicity is the most common, though it mostly remains mild to moderate and does not require discontinuation of treatment. More than a third of pat...
Source: Annales de Dermatologie et de Cenereologie - April 17, 2018 Category: Dermatology Authors: Sibaud V, Boulinguez S, Pagès C, Riffaud L, Lamant L, Chira C, Boyrie S, Vigarios E, Tournier E, Meyer N Tags: Ann Dermatol Venereol Source Type: research

What ’s Next (Generation) for the Diagnosis of Chronic Meningitis?
Chronic meningitis is a syndrome defined by the presence of clinical signs and symptoms of meningitis or meningoencephalitis with a persisting cerebral spinal fluid (CSF) pleocytosis that are present for at least 4 weeks. The differential diagnosis is broad, with categories including neoplastic, paraneoplastic, autoimmune, and noninfectious inflammatory disorders and central nervous system (CNS) infections. The exact frequency of the different etiologies often varies tremendously across reports; however, among most institutions, common infectious causes of chronic meningitis includeMycobacterium tuberculosis and fungal men...
Source: JAMA Neurology - April 16, 2018 Category: Neurology Source Type: research

A Glimpse into Uveitis in the Aging Eye: Pathophysiology, Clinical Presentation and Treatment Considerations
AbstractUveitis describes a group of inflammatory conditions of the eye that have various underlying causes and clinical presentations. Susceptibilities to uveitis in the elderly may be attributed to age-related risk factors such as immunosenescence, increased immunological inflammatory mediators, and autoimmunity. Overall, anterior uveitis is more common than posterior and panuveitis in the general population and also in the elderly. Some causes of uveitis in the elderly are herpes simplex virus, ocular ischemic syndrome, sarcoidosis, and central nervous system lymphoma, and these will be discussed in detail herein. Eye c...
Source: Drugs and Aging - April 16, 2018 Category: Geriatrics Source Type: research

Granuloma of the labial minor salivary glands in tuberculosis
In conclusion, a case of labial minor salivary gland granulomas occurring in the course of tuberculosis is reported. Tuberculosis should be included in the differential diagnoses of labial minor salivary gland granulomas as treatments may be more complex than those for other granulomas including sarcoidosis.
Source: Journal of Oral and Maxillofacial Pathology - April 13, 2018 Category: ENT & OMF Authors: Adriana Handra-Luca Source Type: research

ACE phenotyping in Gaucher disease
Conclusions The conformation of ACE is tissue-specific. In Gaucher disease, ACE produced by activated splenic macrophages differs from that in hepatic macrophages, as well as from macrophages and dendritic cells in sarcoid granulomas. The observed differences are likely due to altered ACE glycosylation or sialylation in these diseased organs. The conformational differences in ACE may serve as a specific biomarker for Gaucher disease.
Source: Molecular Genetics and Metabolism - April 13, 2018 Category: Genetics & Stem Cells Source Type: research

A Case of a Cardiac Resynchronization Therapy-Defibrillator Exhibiting a Lower and Alternately Variable Basic Rate.
Authors: Iwazaki K, Kojima T, Murasawa T, Yokota J, Tanimoto H, Matsuda J, Fukuma N, Matsubara T, Shimizu Y, Oguri G, Hasumi E, Kubo H, Chang K, Fujiu K, Komuro I Abstract A cardiac resynchronization therapy defibrillator (CRT-D) (Medtronic Inc. Protecta XT) was implanted in a 67-year-old man who had cardiac sarcoidosis with extremely low cardiac function. He had ventricular tachycardia which was controlled by catheter ablation, medication and pacing. The programmed mode was DDI, lower rate was 90 beats/minute, paced AV delay was 150 ms, and the noncompetitive atrial pacing (NCAP) function was programmed as 300 ms....
Source: International Heart Journal - April 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Pulmonary hypertension in patients with interstitial lung disease
Publication date: Available online 29 March 2018 Source:Pulmonary Pharmacology & Therapeutics Author(s): Theodoros Karampitsakos, Argyrios Tzouvelekis, Serafeim Chrysikos, Demosthenes Bouros, Iraklis Tsangaris, Wassim H. Fares Interstitial lung diseases (ILDs) comprise a broad and heterogeneous group of more than two hundred diseases with common functional characteristics. Their diagnosis and management require a multidisciplinary approach. This multidisciplinary approach involves the assessment of comorbid conditions including pulmonary hypertension (PH) that exerts a dramatic impact on survival. The current Worl...
Source: Pulmonary Pharmacology and Therapeutics - April 2, 2018 Category: Respiratory Medicine Source Type: research

Incidence, Etiology, and Clinicopathologic Features of Endobronchial Benign Lesions: A 10-Year Consecutive Retrospective Study
Conclusions: A consistent proportion of endobronchial benign lesions are reported. One fifth of these are associated with critical stenosis of the airway lumen, requiring rigid bronchoscopy. Among these, aspergillosis is characterized by the poorest prognosis, regardless of host immunity status.
Source: Journal of Bronchology and Interventional Pulmonology - April 1, 2018 Category: Respiratory Medicine Tags: Original Investigations Source Type: research

Tubulointerstitial nephritis and uveitis (TINU) with granulomatosis: a novel report of simultaneous TINU and sarcoidosis in a pediatric patient
Publication date: Available online 31 March 2018 Source:Journal of American Association for Pediatric Ophthalmology and Strabismus Author(s): Valerie Dawson, David Dao, Melanie Leu, Alena Egense MGC, Laide Jinadu, Laura Malone, Janet Alexander
Source: Journal of American Association for Pediatric Ophthalmology and Strabismus - April 1, 2018 Category: Opthalmology Source Type: research

Ten-year experience of transjugular intrahepatic portosystemic shunt for noncirrhotic portal hypertension
Conclusion TIPS is effective in NCPHT but can be technically difficult, especially in the case of cavernoma. Good liver function does not prevent the occurrence of long-term encephalopathy.
Source: European Journal of Gastroenterology and Hepatology - March 31, 2018 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Family history of autoimmune diseases and risk of gastric cancer: a national cohort study
A personal history of autoimmune diseases is associated with an increased incidence of gastric cancer, but whether they share familial susceptibility is still unknown. The contribution of shared environmental or genetic factors toward the observed familial aggregation has not been determined. We used a few Swedish registers, including the Swedish Multigeneration Register and the Cancer Register, to examine the familial risk of gastric cancer among individuals with a family history of a set of autoimmune diseases. Standardized incidence ratios were used to calculate the relative risk. The overall risk of gastric cancer was ...
Source: European Journal of Cancer Prevention - March 31, 2018 Category: Cancer & Oncology Tags: Research Papers: Gastrointestinal Cancer Source Type: research

Tubulointerstitial nephritis and uveitis (TINU) with granulomatosis: a novel report of simultaneous TINU and sarcoidosis in a pediatric patient
Source: Journal of AAPOS - March 31, 2018 Category: Opthalmology Authors: Valerie Dawson, David Dao, Melanie Leu, Alena Egense, MGC, Laide Jinadu, Laura Malone, Janet Alexander Tags: Short Report Source Type: research

ACR partners with MICCAI to make AI a clinical reality
Two influential radiology groups have signed a partnership to foster development...Read more on AuntMinnie.comRelated Reading: Radiology and AI: From bête noire to nuts and bolts Subtle Medical wins NVIDIA Inception Award 4 reasons why AI won't replace radiologists AIUM: Radiologists must get out of their comfort zone Video from ECR 2018: Wiro Niessen on how AI can help youComments: 3/30/2018 3:22:14 AMDr.Sardonicus Very smart.  What would you suggest as a target for AI.   My list   Fix voice recognition Searching the EMR for pertinent history. Be able to produce a list of physicians working...
Source: AuntMinnie.com Headlines - March 30, 2018 Category: Radiology Source Type: news

Utility and safety of endobronchial ultrasound-guided transbronchial needle aspiration in patients with mediastinal and hilar lymphadenopathy: Western region experience
CONCLUSIONS: EBUS-TBNA is a safe and efficacious procedure which can be performed using conscious sedation with high yields. It can be used for the staging of malignancies as well as for the diagnosis of inflammatory and infectious conditions such as sarcoidosis and TB.
Source: Annals of Thoracic Medicine - March 30, 2018 Category: Respiratory Medicine Authors: Ahmed A Aljohaney Source Type: research

Intramedullary Sarcoidosis: MRI and PET Diagnosis
No abstract available
Source: JCR: Journal of Clinical Rheumatology - March 29, 2018 Category: Rheumatology Tags: Images Source Type: research

Hydroxychloroquine: balancing the need to maintain therapeutic levels with ocular safety an update
Purpose of review Antimalarial drugs including chloroquine, its less toxic quinolone-derivative hydroxychloroquine (HCQ), and quinacrine have become cornerstones in the treatment of autoimmune diseases including systemic lupus, rheumatoid arthritis, sarcoidosis, and Sjogren syndrome; cutaneous disorders, antiphospholipid syndrome, and have recently been employed at higher dioses in oncology. Benefits include anti-inflammatory effects, protection against thrombosis, and improved control of hyperglycemia and hyperlipidemia. In general, both the therapeutic advantages and the toxic effects of the drugs correlate with the do...
Source: Current Opinion in Rheumatology - March 27, 2018 Category: Rheumatology Tags: CLINICAL THERAPEUTICS: Edited by William J. McCune Source Type: research

Oral versus inhaled antibiotics for bronchiectasis.
CONCLUSIONS: There is currently no evidence indicating whether orally administered antibiotics are more beneficial compared to inhaled antibiotics. The recent ERS bronchiectasis guidelines provide a practical approach to the use of long-term antibiotics. New research is needed comparing inhaled versus oral antibiotic therapies for bronchiectasis patients with a history of frequent exacerbations, to establish which approach is the most effective in terms of exacerbation prevention, quality of life, treatment burden, and antibiotic resistance. PMID: 29587336 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - March 27, 2018 Category: General Medicine Authors: Spencer S, Felix LM, Milan SJ, Normansell R, Goeminne PC, Chalmers JD, Donovan T Tags: Cochrane Database Syst Rev Source Type: research

Endomyocardial biopsy at the time of ablation or device implantation
ConclusionsRV or LV EMB can be performed safely during EP procedures and can assist with diagnosis, influencing management. EGM-guided EMB in patients presenting with scar-related VT was low yield for specific pathologies.
Source: Journal of Interventional Cardiac Electrophysiology - March 24, 2018 Category: Cardiology Source Type: research

Rare sinonasal lesions.
CONCLUSIONS: In this paper, there were presented five interesting cases of rare sinonasal lesions, in order to highlight the importance of teamwork for a quick and correct diagnosis. PMID: 29556655 [PubMed - in process]
Source: Romanian Journal of Morphology and Embryology - March 23, 2018 Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research

Erratum.
Authors: Tchernev G, Chikoeva AA, Tana M, Tana C Abstract In the article "Transcriptional blood signatures of sarcoidosis, sarcoid-like reactions and tubercolosis and their diagnostic implications" which appeared in Volume 33, Issue 3 (2016) of Sarcoidosis, vasculitis and diffuse lung diseases, the title was given incorrectly. The correct title is "Transcriptional blood signatures of sarcoidosis, sarcoid-like reactions and tuberculosis and their diagnostic implications". PMID: 28079860 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - January 14, 2017 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Acute sarcoid myopathy: a case report and literature review.
We present a case of a 61-year-old man with diagnosis of sarcoidosis whe were evaluated for proximal lower limb weakness within few days of evolution. PMID: 28079855 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - January 14, 2017 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Vitamin D deficiency and activity of sarcoidosis
Conclusion: Patients with hypercalciuria have active disease; it is shown that the active form of the disease is associated with low values of vitamin 25(OH)D in the serum.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Filipovic, S., Violeta, V., Jelica, V., Mihailo, S., Aleksandar, J. Tags: 1.5 Diffuse Parenchymal Lung Disease Source Type: research

Endobronchial ultrasound (EBUS) transbronchial needle aspiration (TBNA) in germ cell cancer patients with mediastinal lymphadenopathy: A single centre retrospective analysis
Conclusion: Our retrospective analysis demonstrated the coincidence of GCC and SLL to be a frequent finding. EBUS-TBNA is a safe diagnostic approach to confirm SLL. Therefore, aggressive diagnostic approaches such as mediastinoscopy can be avoided. Still, both the prognostic and the immunologic impact of SLL in GCC remain unclear. Further studies should investigate the underlying biological mechanisms and the impact on prognosis.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Schmidt, L., Lauterbach, B., Hansmeier, A., Hartig, I., Kessler, T., Schliemann, C., Schulze, A. B., Wardelmann, E., Pühse, G., Berdel, W., Wiewrodt, R., Mohr, M. Tags: 1.4 Interventional Pulmonology Source Type: research

Transcriptional blood signatures of sarcoidosis, sarcoid-like reactions and tubercolosis and their diagnostic implications.
Authors: Tchernev G, Chokoeva AA, Tana M, Tana C Abstract N/A. PMID: 27759000 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 21, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Subacute sarcoid myositis with ocular muscle involvement; a case report and review of the literature.
We describe a case of acute to subacute sarcoid myositis of the skeletal and extraocular muscles. Typical ophthalmic involvement (manifested by infiltration of the ocular adnexa, intraocular inflammation, or infiltration of the retrobulbar visual pathways) and extraocular sarcoid myositis (as with the present case) is infrequently reported. It is important to keep in mind the rare yet perhaps underestimated entity of sarcoid myositis, and to utilize muscle biopsy and imaging tests for appropriate diagnosis and management of patients with sarcoidosis. PMID: 27758998 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 21, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Pulmonary stenting for the treatment of sarcoid induced pulmonary vascular stenosis.
CONCLUSIONS: Pulmonary vascular stenosis from external compression can be a rare but unrecognized caused of worsening symptoms in advanced sarcoidosis. Pulmonary vascular angioplasty and stenting can provide clinical benefit in select patients. PMID: 27758995 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 21, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Extensive pulmonary sarcoid reaction in a patient with BMPR-2 associated idiopathic pulmonary arterial hypertension.
We describe a case of a 35-year-old woman with idiopathic pulmonary arterial hypertension (IPAH) and a novel BMPR2 mutation, who underwent a successful lung transplantation.  Extensive granulomatous inflammation was seen in the resected lungs. The granulomatous inflammation found in the histology supports  a sarcoid-like reaction due to pulmonary hypertension in the context of the BMPR2 mutation. PMID: 27537724 [PubMed - as supplied by publisher]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - August 19, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Pulmonary metastases from low grade sarcoma in a patient with pulmonary sarcoidosis. Sarcoidosis or sarcoid-like reaction?
Authors: Majori M, Anghinolfi M, Gnetti L, Casalini AG Abstract An asymptomatic man with previous histopatological diagnosis of pulmonary sarcoidosis in radiological follow-up (stable for about 4 years) presented massive right pleural effusion. After drainage, CT of the chest showed an increase in number and size of pulmonary nodules compared to the last check (8 months before). Surgical pulmonary biopsies were performed with the diagnosis of metastases from low grade sarcoma. The primary tumor was localized to the right buttock. Given the absence of symptoms, the extent of disease and many comorbidities the patien...
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - August 19, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Papular sarcoidosis of the knees. A frequent form of presentation of systemic sarcoidosis.
CONCLUSION: Papular sarcoidosis of the knees can be considered a relatively frequent form of cutaneous sarcoidosis usually present at the beginning of the disease that can be useful for the diagnosis of sarcoidosis. It is mainly observed in acute forms of sarcoidosis and can be considered a sign of good prognosis. PMID: 27055837 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 9, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Lung transplantation for pulmonary sarcoidosis. Twenty-five years of experience in the USA
Conclusions Recipients of lung transplants for pulmonary sarcoidosis had similar outcomes compared with non-sarcoid lung recipients.
Source: Thorax - March 14, 2016 Category: Respiratory Medicine Authors: Taimeh, Z., Hertz, M. I., Shumway, S., Pritzker, M. Tags: Epidemiologic studies, Interstitial lung disease, Cardiothoracic surgery, Transplantation Research letter Source Type: research

Propionibacterium acnes isolated from lymph nodes of patients with sarcoidosis.
We report two non-Japanese patients in whom mediastinoscopy was performed in order to obtain lymph node tissue for histopathology, which was suggestive for sarcoidosis. Bacterial culture of these uncontaminated mediastinal lymph nodes revealed P. acnes in both patients. As shown in these two cases, P. acnes can be isolated from sterile biopsied sarcoid lymph nodes of non-Japanese patients and supports the belief that there is an etiologic link between P. acnes sarcoidosis. Further elucidation could provide an opening to novel strategies using antibiotics for treating sarcoidosis. PMID: 26422574 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 3, 2015 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Sarcoid in cancer patients: clinical characteristics and associated disease status.
CONCLUSION:   While sarcoid often presents at initial diagnosis or staging of cancer, in a significant number of patients, it appears in association with recurrence or second malignancy. PMID: 26422564 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 3, 2015 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Cigarette smoking and male sex are independent and age concomitant risk factors for the development of ocular sarcoidosis in a New Orleans sarcoidosis population.
CONCLUSION: To date, there are few dedicated investigations of risk factors for OS, especially smoking. This investigation identified male sex, age, and tobacco exposure as independent risk factors for OS. Though disease duration did not withstand regression analysis in this moderately sized group, age at chart review suggests screening for OS should not remit but rather intensify in aging patients with sarcoidosis. (Sarcoidosis Vasc Diffuse Lung Dis 2015; 32: 183-143). PMID: 26278693 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - August 19, 2015 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Evaluation of Mediastinal Lymph Nodes in Sarcoidosis, Sarcoid Reaction, and Malignant Lymph Nodes Using CT and FDG-PET/CT
Abstract: The aim of this study was to analyze the clinical, computed tomography (CT), and positron emission tomography (PET) findings of sarcoidosis, sarcoid reaction, and malignant lymph nodes (LNs) to the results of transbronchial LN aspiration and biopsy (TBNA). The TBNA results of mediastinal and hilar LNs of 152 patients in our hospital from July 2008 to March 2013 were retrospectively reviewed. Two independent radiologists measured the size and attenuation of LNs on CT and assessed the probability of the 3 categories: sarcoidosis (n = 36), sarcoid reaction (n = 25), or malignant LNs (n = 91). The total v...
Source: Medicine - July 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Sarcoidosis or sarcoid-like reaction developed during the follow-up of malignant tumors: difficulties in differentiation from recurrent or metastatic diseases
Abstract Sarcoidosis or sarcoid-like reaction can occur or manifest several years after completion of treatment during the long-term follow-up of malignant tumors, often creating difficulty in differentiating these lesions from recurrent or metastatic malignant tumors on imaging studies. In recent years, CT and positron-emission tomography (PET) have been widely used in follow-up of malignant tumors; and findings in these studies are similar for sarcoidosis/sarcoid-like reaction and recurrent/metastatic diseases, special caution is needed in diagnosing either of these disorders. In patients who show results i...
Source: International Cancer Conference Journal - October 1, 2014 Category: Cancer & Oncology Source Type: research