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Total 5082 results found since Jan 2013.

Can pulmonary sarcoidosis trigger a progressive multifocal leukoencephalopathy? Considerations from a case series and a review of literature
Clinical Case Reports, EarlyView.
Source: Clinical Case Reports - September 21, 2018 Category: General Medicine Authors: Irene Gamperl , Christian Enzinger , Alexander Pichler , Michael Feichtinger , Thomas Schlager , Elisabeth Fertl Source Type: research

Acute Tubulointerstitial Nephritis in an HLA-B27-positive Patient With Axial Spondyloarthritis Being Treated With Adalimumab
We report a case of acute nongranulomatous tubulointerstitial nephritis in an HLA-B27-positive patient with axial spondyloarthritis and Crohn's disease being treated with adalimumab.ResumenLos antagonistas del factor de necrosis tumoral-alfa (ATNF) se utilizan en el tratamiento de múltiples enfermedades, como artritis psoriásica, enfermedad de Crohn, espondilitis anquilosante, artritis idiopática juvenil, generalmente, cuando son refractarias al tratamiento de primera línea.1 La utilización de los ATNF se ha asociado con la inducción de enfermedades autoinmunes, como lupus eritematoso sistémico-like, vasculitis, sar...
Source: Reumatologia Clinica - September 20, 2018 Category: Rheumatology Source Type: research

Stop that glucose getting to heart!
AbstractCardiac inflammation/infection imaging with 18F-FDG has been very useful in guiding patient management in conditions such as cardiac sarcoidosis, myocarditis, device infections, and prosthetic implant-related infections. Various protocols have been described to suppress normal myocardial glucose uptake. Certainly, there is need for standardization of protocols but adaptation of protocol to suit individual patient needs is also equally important. In the current article in this issue, Alexandra Cl ément et al have shown that a 7-day ketogenic diet can be used as an alternative method in mice models. This may work we...
Source: Journal of Nuclear Cardiology - September 20, 2018 Category: Nuclear Medicine Source Type: research

Sarcoidosis presenting as isolated anasarca and hypercalcemia
Case Report: A 62-year-old woman presents to clinic for second evaluation. Previously healthy, she initially presented for care several months earlier with anasarca. Initial workup was notable for normal renal function, calcium level, and liver function tests, no proteinuria, and echocardiogram demonstrating mild diastolic dysfunction and concentric left ventricular hypertrophy but preserved systolic function. One month later the patient developed severe, acute, symptomatic hypercalcemia with a calcium level of 14.7 mg/dL (corrected to 15.3 mg/dL).
Source: The American Journal of Medicine - September 18, 2018 Category: General Medicine Authors: Perrin E. Romine, Keith D. Eaton, Kelly G. Paulson, Rouba Hadi, Douglas S. Paauw Tags: Clinical Communication to the Editor Source Type: research

A Multi-center, Prospective, Single-blind, Controlled Trial Comparing Diagnostic Value of Different EUS-FNA Techniques
Conditions:   Neoplasms;   Infection;   Inflammation;   Lymphoma;   Cancer;   Sarcoid;   Mass Lesion Interventions:   Procedure: Standard suction, slow-pull, wet suction;   Procedure: Standard suction, wet suction, slow-pull;   Procedure: Slow-pull, standard suction, wet suction;   Procedure: Slow-pull, wet suction, standard suction;   Procedure: Wet suction, standard suction, slow-pull;   Procedure: Wet s uction, slow-pull, standard suction Sponsor:   Shanghai Zhongshan Hospital Recruiting
Source: - September 17, 2018 Category: Research Source Type: clinical trials

Optimizing cardiac sarcoid imaging with FDG PET: Lessons from studies of physiologic regulation of myocardial fuel substrate utilization
Source: Journal of Nuclear Cardiology - September 17, 2018 Category: Nuclear Medicine Source Type: research

Necrobiosis lipoidica associated with sarcoidosis
Journal of Cutaneous Pathology,Volume 0, Issue ja, -Not available-.
Source: Journal of Cutaneous Pathology - September 14, 2018 Category: Pathology Authors: Jack Lee , Richard H Flowers , Margaret M Cocks , Mary Margaret B Noland Source Type: research

Prognosticating Outcomes in Interstitial Lung Disease by Mediastinal Lymph Node Assessment: An Observational Cohort Study with Independent Validation.
CONCLUSIONS: MLN enlargement predicts TFS and hospitalization risk in ILD, and is associated with decreased levels of a key circulating cytokine sCD40L. Incorporating MLN and cytokine findings into current prediction models might improve ILD prognostication. PMID: 30216085 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - September 14, 2018 Category: Respiratory Medicine Authors: Adegunsoye A, Oldham JM, Bonham C, Hrusch C, Nolan P, Klejch W, Bellam S, Mehta U, Thakrar K, Pugashetti JV, Husain AN, Montner SM, Straus CM, Vij R, Sperling AI, Noth I, Strek ME, Chung JH Tags: Am J Respir Crit Care Med Source Type: research

Neuroimmunology and rheumatology: overlap and differential diagnoses.
Abstract Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are chronic inflammatory diseases of the central nervous system (CNS). They may cause inflammation in the brain, spinal cord and optic nerve. Both conditions must be differentiated from CNS manifestations of other systemic autoimmune diseases such as systemic lupus erythematosus (SLE), Sjögren's syndrome, autoinflammtory diseases and sarcoidosis, since amongst others myelitis and optic nerve inflammation may also occur in these conditions. Nevertheless, coexistence of MS or NMOSD with rheumatic disorders such as SLE or Sjögren's ...
Source: Der Nervenarzt - September 13, 2018 Category: Neurology Authors: Trebst C, Kümpfel T Tags: Nervenarzt Source Type: research

Arthritis in sarcoidosis: A multicentric study from India
International Journal of Rheumatic Diseases, EarlyView.
Source: APLAR Journal of Rheumatology - September 6, 2018 Category: Rheumatology Authors: , Vikas Agarwal , Vinita Agrawal , Amita Aggarwal , Parshant Aggarwal , Abhra C. Chowdhury , Parasar Ghosh , Avinash Jain , Able Lawrence , Durga P. Misra , Ramnath Misra , Madhusmita M. Mohapatra , Alok Nath , Vir S. Negi , S Source Type: research

Sarcoidosis presenting with facial swelling (Heerfordt syndrome)
Clinical Case Reports, EarlyView.
Source: Clinical Case Reports - September 6, 2018 Category: General Medicine Authors: Satish Maharaj , Megan Brown , Karan Seegobin , Carmen Isache Source Type: research

Importance of extracardiac FDG uptake to diagnose cardiac sarcoidosis
Source: Journal of Nuclear Cardiology - September 5, 2018 Category: Nuclear Medicine Source Type: research

Expression of vascular endothelial growth factor (VEGF) in equine sarcoid
Sarcoids are the mostcommon skin tumors in horses, characterized by rare regression, invasiveness and high recurrence following surgical intervention and Delta Papillomaviruses are widely recognized as the cau...
Source: BMC Veterinary Research - September 3, 2018 Category: Veterinary Research Authors: Manuela Martano, Karen Power, Brunella Restucci, Ilaria Pagano, Gennaro Altamura, Giuseppe Borzacchiello and Paola Maiolino Tags: Research article Source Type: research

Sarcoidosis of the fallopian tube: A rare case study with confirmed Propionibacterium acnes infection
Journal of Obstetrics and Gynaecology Research, EarlyView.
Source: Journal of Obstetrics and Gynaecology Research - September 3, 2018 Category: OBGYN Authors: Takashi Kuno , Masahito Tachibana , Soshi Muramatsu , Yoshinobu Eishi , Ayako Fujimine , Hideki Tokunaga , Nobuo Yaegashi Source Type: research

T lymphocyte immunophenotyping in bronchoalveolar lavage on AQUIOS CL ® cytometer.
T lymphocyte immunophenotyping in bronchoalveolar lavage on AQUIOS CL® cytometer. J Immunol Methods. 2018 Oct;461:91-99 Authors: Humeau C, Darrouzain F, Gouilleux-Gruart V Abstract Bronchoalveolar lavage (BAL) is one of the tests for orientation in the diagnosis of diffuse parenchymal lung disease. Lymphocyte subpopulation study by flow cytometry in the BAL is part of the criteria for the diagnosis of sarcoidosis. We investigated the feasibility of T lymphocyte immunophenotyping in BAL on a new automaton: AQUIOS CL®, a closed access cytometer with fully automated process designed for blood samples. ...
Source: Journal of Immunological Methods - August 31, 2018 Category: Allergy & Immunology Authors: Humeau C, Darrouzain F, Gouilleux-Gruart V Tags: J Immunol Methods Source Type: research

Potential Clinical Utility of FDG-PET in Non-malignant Pulmonary Disorders: A Pilot Study.
CONCLUSIONS: FDG-PET scan can be used as an important adjunct non-invasive investigation in diagnosing and monitoring of various benign lung conditions. It also helps in assessing whole body disease burden which may change therapeutic decisions. PMID: 30152649 [PubMed - in process]
Source: Indian Journal of Chest Diseases and Allied Sciences - August 30, 2018 Category: Respiratory Medicine Tags: Indian J Chest Dis Allied Sci Source Type: research

Neurosarcoidosis Presenting with Obstructive Hydrocephalus Successfully Treated with Endoscopic Third Ventriculostomy.
Authors: Nakayasu H, Shirai T, Tanaka Y, Sato T, Muro H Abstract A 58-year-old Japanese woman complained of unstable gait and dizziness lasting for a month. She had been diagnosed histologically with pulmonary and cutaneous sarcoidosis and attended outpatient clinics for routine checkups. Head computed tomography and magnetic resonance imaging (MRI) indicated obstructive hydrocephalus caused by a contrast-enhanced lesion in the cerebral aqueduct. The patient underwent endoscopic third ventriculostomy and a biopsy of the lesion, leading to the diagnosis of neurosarcoidosis. This was a rare case of neurosarcoidosis p...
Source: Internal Medicine - August 29, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Comparing the Clinical Performance of the New 19-G ViziShot FLEX and 21- or 22-G ViziShot 2 Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Needles.
Conclusion EBUS-TBNA with a 19-G needle was useful for diagnosing retinal hemangioblastoma and tuberculous lymphadenitis as well as for PD-L1 testing after 21- and 22-G biopsies were unsuccessful. PMID: 30146572 [PubMed - as supplied by publisher]
Source: Internal Medicine - August 29, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Incidental Hepatic Granulomas in a Young Woman
Hepatic granulomas are identified in approximately 3% to 4% of liver biopsies in the Western world. Their presence raises a broad differential diagnosis for the pathologist to consider, including infectious, immune-mediated, and drug-induced etiologies. Certain histologic features of granulomas and the adjacent liver parenchyma can help narrow the differential diagnosis, although clinical and laboratory correlation is often necessary to establish a definitive diagnosis. The purpose of this article is to review the morphologic classification of hepatic granulomas and to discuss hepatic sarcoidosis, one of the most common im...
Source: Pathology Case Reviews - August 29, 2018 Category: Pathology Tags: Case Reviews Source Type: research

Forbearance with Bronchoscopy: A Review of Gratuitous Indications.
We present an overview on conditions where expectations from bronchoscopy exceeds the evidence in the literature and coin the term "Forbearance with Bronchoscopy" for situations where this popular tool may not be the most appropriate initial approach. PMID: 30171862 [PubMed - as supplied by publisher]
Source: Chest - August 29, 2018 Category: Respiratory Medicine Authors: Deshwal H, Avasarala SK, Ghosh S, Mehta AC Tags: Chest Source Type: research

Sarcoidosis secondary to lymphocyte active immunotherapy treated with infliximab
Abstract: A hospital-based cross-sectional study was performed, including 117 psoriatic patients and 117 controls matched for age, gender, and body mass index. Psoriatic patients had higher levels of serum uric acid (6.25 ± 1.62 vs 5.71 ± 1.35 mg/dl; P=0.019) and significantly greater prevalence of hyperuricemia (31.6% vs 16.2%; P=0.009) than individuals without psoriasis. Psoriatic patients had significantly higher serum uric acid than controls in subjects without metabolic syndrome. Multivariate logistic regressi on analysis showed that psoriasis can be a strong predictor of hyperuricemia (odds ratio 2.61; 95% confiden...
Source: Anais Brasileiros de Dermatologia - August 27, 2018 Category: Dermatology Source Type: research

Development of mediastinal adenitis six weeks after endobronchial ultrasound-guided transbronchial needle aspiration
Publication date: Available online 25 August 2018Source: Respiratory Medicine Case ReportsAuthor(s): Sho Shimada, Haruhiko Furusawa, Toshihisa Ishikawa, Eisaku Kamakura, Takafumi Suzuki, Yuta Watanabe, Takasato Fujiwara, Shinichiro Tominaga, Keiko Mitaka Komatsuzaki, Ichiro NatsumeAbstractA 60-year-old man visited our hospital for further examination of an abnormal chest radiograph. Computed tomography (CT) images revealed enlarged mediastinal lymph nodes and multiple pulmonary nodules.Further evaluation by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) was performed and he was diagnosed with ...
Source: Respiratory Medicine Case Reports - August 26, 2018 Category: Respiratory Medicine Source Type: research

Viewpoints in the Diagnosis and Treatment of Cardiac Sarcoidosis: Proposed Modification of Current Guidelines
Clinical Cardiology,Volume 0, Issue ja, -Not available-.
Source: Clinical Cardiology - August 25, 2018 Category: Cardiology Authors: Dae ‐Won Sohn M.D , Jun‐Bean Park M.D , Seung‐Pyo Lee M.D , Hyung‐Kwan Kim M.D , Yong‐Jin Kim M.D Source Type: research

BAL Cell Gene Expression is Indicative of Outcome and Airway Basal Cell Involvement in IPF.
CONCLUSIONS: Our results identify and validate a BAL signature that predicts mortality in IPF and improves the accuracy of outcome prediction based on clinical parameters. The BAL signature associated with mortality unmasks a potential role for airway basal cells in IPF. PMID: 30141961 [PubMed - as supplied by publisher]
Source: Am J Respir Crit Car... - August 24, 2018 Category: Intensive Care Authors: Prasse A, Binder H, Schupp JC, Kayser G, Bargagli E, Jaeger B, Hess M, Rittinghausen S, Vuga L, Lynn H, Violette S, Jung B, Quast K, Vanaudenaerde B, Xu Y, Hohlfeld JM, Krug N, Herazo-Maya JD, Rottoli P, Wuyts WA, Kaminski N Tags: Am J Respir Crit Care Med Source Type: research

DNA Methylation Changes in Lung Immune Cells are Associated with Granulomatous Lung Disease.
CONCLUSIONS: Our study highlights the significance of epigenetic marks in lung immune response in granulomatous lung disease. PMID: 30141971 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory Cell and Molecular Biology - August 24, 2018 Category: Molecular Biology Authors: Yang IV, Konigsberg I, MacPhail K, Li L, Davidson EJ, Mroz PM, Hamzeh N, Gillespie M, Silveira LJ, Fingerlin TE, Maier LA Tags: Am J Respir Cell Mol Biol Source Type: research

EP News: Case Reports
Cardiac sarcoidosis is a significant cause of morbidity and mortality in patients with sarcoidosis. Cardiac manifestations of disease are largely dependent on the region of inflammation and subsequent fibrosis and scar. Although atrial arrhythmias occur in approximately one-third of patients with cardiac sarcoidosis, sinus node dysfunction is rare. Bhaskaran et  al (DOI: described a case of a 42-year-old previously healthy patient who presented with symptomatic sinus bradycardia with intermittent junctional bradycardia and sinus pauses up to 8 seconds with intermittent episodes ...
Source: Heart Rhythm - August 23, 2018 Category: Cardiology Authors: T. Jared Bunch Tags: EP News Source Type: research

Identification of a novel missense mutation in the NOD2 gene in a Chinese child with early-onset sarcoidosis
Xiaopo Wang, Xiaofeng Zhang, Wei Zhang, Jianfang SunIndian Journal of Dermatology, Venereology, and Leprology 2018 84(5):645-645
Source: Indian Journal of Dermatology, Venereology and Leprology - August 23, 2018 Category: Dermatology Authors: Xiaopo Wang Xiaofeng Zhang Wei Zhang Jianfang Sun Source Type: research

FDG PET/CT of Metabolic Myopathy With Posttreatment Follow-up
A 38-year-old woman presented with extreme fatigue and multiple lung nodules. She was referred for a PET/CT, which demonstrated multiple FDG-avid pulmonary nodules and lymph nodes with intense uptake within multiple muscle groups predominantly involving the paraspinal muscles and muscles of mastication. Histopathology of a paraspinal muscle biopsy revealed increased skeletal muscle lipid stores and increased mitochondria with normal morphology. This abnormality is seen in metabolic myopathy due to a disorder of fatty acid oxidation. Transbronchial biopsy showed no evidence of sarcoidosis. The patient was commenced on carni...
Source: Clinical Nuclear Medicine - August 22, 2018 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Disseminated Granulomatous Perifollicular Dermatosis With Comedones: A Follicular Variant of Lichen Nitidus or a New Entity?
We report a case of a 57-year-old male patient presenting clinically numerous acquired disseminated follicular papules and comedones, showing isolated perifollicular sarcoid-like granulomatous inflammatory infiltrates at the histological examination. These lesions experienced a complete spontaneous resolution after several months. The possibility that this disseminated, epithelioid, granulomatous, perifollicular dermatosis may represent an isolated follicular variant of lichen nitidus or a previously nonreported skin disorder is discussed.
Source: The American Journal of Dermatopathology - August 21, 2018 Category: Pathology Tags: Extraordinary Case Report Source Type: research

New Research Provides Insight into Neurosarcoidosis
New research into neurosarcoidosis suggests certain clinical and imaging features are indicative of a more aggressive neurological disease. The study provides insight into the clinical features of neurosarcoidosis, as well as the relationship between neurological involvement and systemic disease...
Source: The Rheumatologist - August 21, 2018 Category: Rheumatology Authors: Natasha Yetman Tags: Conditions central nervous system Sarcoidosis Source Type: research

Rising stars of DPLD survival: FVC and exercise desaturation (a single-center study)
Conclusion: The current study determined that FVC% is important in the prediction of mortality. Moreover, it demonstrated a strong relationship between exercise desaturation and PH. PMID: 30119159 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - August 20, 2018 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Bartter syndrome-like phenotype in a patient with diabetes: a case report
ConclusionsPatients presenting with body weakness need serum potassium estimation. Acquired Bartter ’s syndrome although rare, should be ruled out in those with hypokalemia and metabolic alkalosis with increased urinary potassium loss with poor response to potassium replacement.
Source: Journal of Medical Case Reports - August 17, 2018 Category: General Medicine Source Type: research

PET/CT in the Diagnosis and Workup of Sarcoidosis: Focus on Atypical Manifestations
RadioGraphics, Ahead of Print.
Source: Radiographics - August 17, 2018 Category: Radiology Authors: Gensuke Akaike Malak Itani Hardik Shah Jitesh Ahuja Burcak Yilmaz Gunes Richard Assaker Fatemeh Behnia Source Type: research

Elevated Levels of Intelectin-1, a Pathogen-binding Lectin, in the BAL Fluid of Patients with Chronic Eosinophilic Pneumonia and Hypersensitivity Pneumonitis.
Conclusions The results of the present study suggest that hITLN-1 may be involved in the pathogenesis of ICEP and HP, and that an increase in the hITLN-1 concentration in the BAL fluid may represent a new biomarker for these diseases. PMID: 30101907 [PubMed - as supplied by publisher]
Source: Internal Medicine - August 15, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Mediastinitis following endobronchial ultrasound-guided transbronchial needle aspiration.
CONCLUSION: EBUS-TBNA is associated with a risk of mediastinitis that may manifest as an isolated fever arising within hours of the procedure. The pathogens responsible are usually contaminants from the oropharynx such as Streptococcus sp, probably inoculated directly into the mediastinum during transbronchial needle aspiration. Rapid diagnosis and treatment are necessary in order to reduce morbidity and mortality associated with mediastinitis. PMID: 30098879 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - August 15, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

Multi-system sarcoidosis causing panhypopituitarism: rapid improvement with corticosteroid therapy
Endocrine Practice, Ahead of Print.
Source: Endocrine Practice - August 14, 2018 Category: Endocrinology Authors: Rashid Mahboob Ali A. Rizvi Source Type: research

Pembrolizumab-induced Sarcoid-like Reactions during Treatment of Metastatic Melanoma
Radiology, Ahead of Print.
Source: Radiology - August 14, 2018 Category: Radiology Authors: Sophie C. Cheshire Ruth E. Board Alexandra R. Lewis Laxminarayan D. Gudur Michael J. Dobson Source Type: research

A case of fatal osteolytic hypercalcemia complicated with IgG4-related ophthalmic disease leading to renal failure
AbstractA 40-year-old male was hospitalized with renal impairment and severe hypercalcemia. His concentration of serum IgG4 was high, but serum whole PTH, 1 –25(OH)2 vitamin D3 and PTHrP were not elevated. Computed tomography showed swelling of the bilateral lacrimal glands and systemic lymphadenopathy. The histological findings of lacrimal gland biopsy fulfilled the diagnostic criteria of IgG4-related ophthalmic disease (IgG4ROD). Bone scintigraphy showed increased ectopic uptake in the stomach, heart, lungs, and kidneys. He died on day 16 of admission, although the therapies for hypercalcemia were continued. Autopsy re...
Source: CEN Case Reports - August 14, 2018 Category: Urology & Nephrology Source Type: research

A Randomized Trial Evaluating the Effect of 10 versus 20 Revolutions Inside the Lymph Node on the Diagnostic Yield of EBUS-TBNA in Subjects with Sarcoidosis
Conclusions: The diagnostic yield and specimen adequacy were not different when EBUS-TBNA was performed with 10 or 20 revolutions in subjects with sarcoidosis.Respiration
Source: Respiration - July 24, 2018 Category: Respiratory Medicine Source Type: research

DNA methylation patterns of the S100A14, POU2F3 and SFN genes in equine sarcoid tissues
Publication date: Available online 24 July 2018Source: Research in Veterinary ScienceAuthor(s): E. Semik-Gurgul, T. Ząbek, A. Fornal, M. Wnuk, K. Pawlina-Tyszko, A. Gurgul, J. Klukowska-Rötzler, C. Koch, K. Mählmann, M. Bugno-PoniewierskaAbstractGenetic and epigenetic alterations in the equine sarcoid, a locally invasive skin tumour of equids, are still poorly characterized. Numerous studies have provided reliable evidence for the relationship between the development of cancer and the loss of function of a number of tumour suppressor genes. In the present study, we assessed methylation levels in the promoter region of S...
Source: Research in Veterinary Science - July 24, 2018 Category: Veterinary Research Source Type: research

Serum angiotensin converting enzyme (ACE) has a high negative predictive value in the investigation for systemic sarcoidosis
To examine whether measurement of serum angiotensin converting enzyme (ACE) is useful in diagnosing sarcoidosis in undifferentiated uveitis
Source: American Journal of Ophthalmology - July 24, 2018 Category: Opthalmology Authors: Rachael L. Niederer, Ahmed Al-Janabi, Sue L. Lightman, Oren Tomkins-Netzer Tags: Original Articles Source Type: research

A Comprehensive Review of Hepatic Sarcoid
Semin Liver Dis 2018; 38: 284-297 DOI: 10.1055/s-0038-1666853Sarcoidosis is a multisystem inflammatory disease, which is characterized by the development of noncaseating granulomas amid healthy tissue. While most commonly affecting the mediastinum and/or lungs, sarcoid can also affect the liver, resulting in “hepatic sarcoid.” The spectrum of disease in hepatic sarcoid is variable, ranging from asymptomatic or mild liver enzyme abnormalities to end-stage liver disease requiring liver transplantation. Because clinically-significant hepatic sarcoid is rare, research on epidemiology, clinical manifestations, and treatment...
Source: Seminars in Liver Disease - July 24, 2018 Category: Gastroenterology Authors: Deutsch-Link, Sasha Fortuna, Danielle Weinberg, Ethan M. Tags: Review Article Source Type: research

Serum Angiotensin-Converting Enzyme Has a High Negative Predictive Value in the Investigation for Systemic Sarcoidosis
To examine whether measurement of serum angiotensin-converting enzyme (ACE) is useful in diagnosing sarcoidosis in undifferentiated uveitis.
Source: American Journal of Ophthalmology - July 24, 2018 Category: Opthalmology Authors: Rachael L. Niederer, Ahmed Al-Janabi, Sue L. Lightman, Oren Tomkins-Netzer Tags: Original article Source Type: research

Serum microRNA-126 and -223 as new-generation biomarkers for sarcoidosis in patients with heart failure.
CONCLUSIONS: Our results demonstrate the potential of serum miR-126 and miR-223 as new-generation biomarkers for the differential diagnosis of cardiac sarcoidosis in patients with heart failure. PMID: 30054123 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - July 24, 2018 Category: Cardiology Authors: Fujiwara W, Kato Y, Hayashi M, Sugishita Y, Okumura S, Yoshinaga M, Ishiguro T, Yamada R, Ueda S, Harada M, Naruse H, Ishii J, Ozaki Y, Izawa H Tags: J Cardiol Source Type: research