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Total 5607 results found since Jan 2013.

Exercise ‐related sudden cardiac death of an American football player with arrhythmogenic right ventricular dysplasia/cardiomyopathy AND sarcoidosis
This case emphasizes the value of cardiac MRI and genetic testing in the early phase of ARVD/C. It also emphasizes the increased risk of SCD for patients with ARVD/C participating in competitive sports, even with immediate cardiopulmonary resuscitation. Key Clinical MessageThis case emphasizes the value of cardiac MRI and genetic testing in the early phase of ARVD/C. It also emphasizes the increased risk of SCD for patients with ARVD/C participating in competitive sports, even with immediate cardiopulmonary resuscitation.
Source: Clinical Case Reports - February 19, 2019 Category: General Medicine Authors: Andreas M üssigbrodt, Helge Knopp, Csilla Czimbalmos, Cosima Jahnke, Sergio Richter, Daniela Husser, Tanja Gradistanac, Gerhard Hindricks Tags: CASE REPORT Source Type: research

Diagnostic performance of F 18 FDG PET in cardiac sarcoidosis: Are we getting closer to the truth?
Source: Journal of Nuclear Cardiology - February 15, 2019 Category: Nuclear Medicine Source Type: research

Imaging cardiac sarcoidosis with FDG-PET: Take a look at the right side!
Source: Journal of Nuclear Cardiology - February 15, 2019 Category: Nuclear Medicine Source Type: research

What is PET/MRI's value for cardiac sarcoidosis?
Much has been researched and written about the promise of PET/MRI. While the...Read more on AuntMinnie.comRelated Reading: Ga-68 PSMA-11 PET/MRI benefits prostate cancer patients TOF PET/MRI makes dose reduction viable for breast cancer How effective is PET/MRI for rectal cancer? PET/MRI with ferumoxytol MR contrast performs well for pediatric patients Cardiac FDG-PET/MRI's role in Anderson-Fabry disease
Source: AuntMinnie.com Headlines - February 12, 2019 Category: Radiology Source Type: news

64-Year-Old Man With Subacute Altered Mental Status and Headache
A 64-year-old man from Iowa with a medical history of sarcoidosis, managed with prednisone, 20 mg/d, for the past 5 months, presented to the emergency department with gradual-onset, progressive altered mental status and headaches of 1 month ’s duration. Previously, he was cognitively intact according to his daughter. He had become unable to perform normal daily tasks such as unlocking doors and holding normal conversations. Additionally, he reported a generalized, throbbing, constant headache associated with intermittent blurry visio n.
Source: Mayo Clinic Proceedings - February 12, 2019 Category: Internal Medicine Authors: Nandini S. Mehra, Robert C. Ward, Meltiady Issa Tags: Residents ’ clinic Source Type: research

Using FDG-PET to guide targeted cardiac magnetic resonance imaging in patients with suspected cardiac sarcoidosis
Source: Journal of Nuclear Cardiology - February 8, 2019 Category: Nuclear Medicine Source Type: research

Focal Myositis of the Leg Presenting as Fever of Unknown Origin Detected by FDG PET/CT
We present one case of focal myositis involving the left proximal vastus lateralis and vastus intermedius, and left soleus showing intense FDG uptake on FDG PET/CT. This case indicates that focal myositis should be considered as a differential diagnosis in patients with focal hypermetabolic muscular lesions, including benign and malignant tumors, necrotizing autoimmune myopathy, nodular fasciitis, myositis ossificans, and muscular sarcoidosis.
Source: Clinical Nuclear Medicine - February 7, 2019 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Hypertrophic cervical spine pachymeningitis due to sarcoidosis: a case report
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Source: Hospital Practice - February 6, 2019 Category: Hospital Management Authors: Hussam A. Yacoub P. Mark Li Joshua A. Bemporad Dmitry Khaitov Daniel F. Brown Source Type: research

Takayasu's Arteritis and Sarcoidosis in the Era of Advanced Molecular Imaging
This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - February 4, 2019 Category: Rheumatology Authors: Blas Y. Betancourt, Mark A. Ahlman, Peter C. Grayson Tags: Clinical Image Source Type: research

Multiple Sclerosis and Autoimmune Neurology of the Central Nervous System.
Abstract Autoimmune disorders of the central nervous system are common and often affect people in the most productive years of their lives. Among primary autoimmune diseases of the central nervous system, multiple sclerosis is most prevalent in the United States. Many other autoantibody-mediated neurologic syndromes have been identified within the past 2 to 3 decades, including neuromyelitis optica and anti-N-methyl-D aspartate receptor encephalitis. Finally, the central nervous system can also be affected by systemic autoimmune diseases such as sarcoidosis. Many of these diseases are treatable when detected early...
Source: The Medical Clinics of North America - February 3, 2019 Category: General Medicine Authors: Galetta KM, Bhattacharyya S Tags: Med Clin North Am Source Type: research

Science Saturday: A hard look at a devastating heart disease
Though rare, cardiac sarcoidosis is a condition that can wreak havoc on the heart. It can be triggered by environmental or infectious agents and is characterized by an overactive immune response, involving clusters of white blood cells that aggregate in heart tissue. Those clusters can result in the need for a pacemaker, and may even [...]
Source: News from Mayo Clinic - February 2, 2019 Category: Databases & Libraries Source Type: news

Role of 18F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring: Addition to the Expert Consensus
Source: Journal of Nuclear Medicine - February 1, 2019 Category: Nuclear Medicine Authors: Lu, Y., Sweiss, N. J. Tags: Letters Source Type: research

Reply: Role of 18F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring: Addition to the Expert Consensus
Source: Journal of Nuclear Medicine - February 1, 2019 Category: Nuclear Medicine Authors: Chareonthaitawee, P., Blankstein, R. Tags: Letters Source Type: research

Diagnosis and differential diagnosis of large-vessel vasculitides
AbstractThere are no universally accepted diagnostic criteria for large-vessel vasculitides (LVV), including giant cell arteritis (GCA) and Takayasu arteritis (TAK). Currently, available classification criteria cannot be used for the diagnosis of GCA and TAK. Early diagnosis of these two diseases is quite challenging in clinical practice and may be accomplished only by combining the patient symptoms, physical examination findings, blood test results, imaging findings, and biopsy results, if available. Awareness of red flags which lead the clinician to investigate TAK in a young patient with persistent systemic inflammation...
Source: Rheumatology International - February 1, 2019 Category: Rheumatology Source Type: research

Evaluation of MyoStrain ™ in Clinical Practice
Conditions:   Cardiac Failure;   Coronary Artery Disease;   Sarcoidosis;   Amyloidosis;   Lupus;   Myocarditis;   Drug Toxicity Intervention:   Procedure: Diagnostic Test: Myostrain Sponsor:   University of Kansas Medical Center Not yet recruiting
Source: ClinicalTrials.gov - January 31, 2019 Category: Research Source Type: clinical trials

Neurosarcoidosis Occurring 6 Years after Onset of Vogt-Koyanagi-Harada Disease
We report a case of the concurrence of VKHD and sarcoidosis, which may share a common pathophysiology. Accumulation of further similar cases is necessary to elucidate the precise mechanism underlying the concurrence of these two diseases.Case Rep Ophthalmol 2019;10:32 –40
Source: Case Reports in Ophthalmology - January 27, 2019 Category: Opthalmology Source Type: research

Odontoid cervical gout causing atlantoaxial instability: case report.
Abstract The authors present a case report of a patient discovered to have a rotatory subluxation of the C1-2 joint and a large retroodontoid pannus with an enhancing lesion in the odontoid process eventually proving to be caused by gout. This patient represented a diagnostic conundrum as she had known prior diagnoses of not only gout but also sarcoidosis and possible rheumatoid arthritis, and was in the demographic range where concern for an oncological process cannot fully be ruled out. Because she presented with signs and symptoms of atlantoaxial instability, she required posterior stabilization to reduce the r...
Source: Journal of Neurosurgery.Spine - January 25, 2019 Category: Neurosurgery Authors: Slavin J, DiStasio M, Dellaripa PF, Groff M Tags: J Neurosurg Spine Source Type: research

Multiple huge “cluster” and “galaxy” signs on chest radiography in a patient with pulmonary tuberculosis
In this article, we present a unique case of active pulmonary tuberculosis, with multiple huge “cluster” signs like fireworks, together with multiple “galaxy” signs. The repeated acid‐fast sputum smears and both bronchial washings were all negative forMycobacterium tuberculosis, but the acid ‐fast culture of sputum taken soon after the first bronchoscopy, and pleural fluid, turned out to be positive forM. tuberculosis at six weeks after admission. The present case clearly demonstrates that the “galaxy” and “cluster” signs are red herring signs of the low rates of isolatingM. tuberculosis, which should b...
Source: Respirology Case Reports - January 25, 2019 Category: Respiratory Medicine Authors: Miku Oda, Takeshi Saraya, Tatsuya Shirai, Narishige Ishikawa, Masachika Fujiwara, Hajime Takizawa Tags: Case Report Source Type: research

The formation and disordered degradation of neutrophil extracellular traps in necrotizing lesions of anti-neutrophil cytoplasmic antibody-associated vasculitis.
Abstract Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is characterized by the production of ANCAs and systemic necrotizing vasculitis in small vessels. Disordered regulation of neutrophil extracellular traps (NETs) is critically involved in the pathogenesis of AAV. NETs are web-like DNA decorated with antimicrobial proteins; they are extruded from activated neutrophils. The principal degradation factor of NETs in vivo is DNase I; however, NETs resistant to DNase I can persist in tissues and lead to the production of ANCAs. Deposition of NETs has been demonstrated in glomerular crescents ...
Source: Am J Pathol - January 21, 2019 Category: Pathology Authors: Masuda S, Nonokawa M, Futamata E, Nishibata Y, Iwasaki S, Tsuji T, Hatanaka Y, Nakazawa D, Tanaka S, Tomaru U, Kawakami T, Atsumi T, Ishizu A Tags: Am J Pathol Source Type: research

Erratum.
Authors: Tchernev G, Chikoeva AA, Tana M, Tana C Abstract In the article "Transcriptional blood signatures of sarcoidosis, sarcoid-like reactions and tubercolosis and their diagnostic implications" which appeared in Volume 33, Issue 3 (2016) of Sarcoidosis, vasculitis and diffuse lung diseases, the title was given incorrectly. The correct title is "Transcriptional blood signatures of sarcoidosis, sarcoid-like reactions and tuberculosis and their diagnostic implications". PMID: 28079860 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - January 14, 2017 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Acute sarcoid myopathy: a case report and literature review.
We present a case of a 61-year-old man with diagnosis of sarcoidosis whe were evaluated for proximal lower limb weakness within few days of evolution. PMID: 28079855 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - January 14, 2017 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Vitamin D deficiency and activity of sarcoidosis
Conclusion: Patients with hypercalciuria have active disease; it is shown that the active form of the disease is associated with low values of vitamin 25(OH)D in the serum.
Source: European Respiratory Journal - November 8, 2016 Category: Respiratory Medicine Authors: Filipovic, S., Violeta, V., Jelica, V., Mihailo, S., Aleksandar, J. Tags: 1.5 Diffuse Parenchymal Lung Disease Source Type: research

Endobronchial ultrasound (EBUS) transbronchial needle aspiration (TBNA) in germ cell cancer patients with mediastinal lymphadenopathy: A single centre retrospective analysis
Conclusion: Our retrospective analysis demonstrated the coincidence of GCC and SLL to be a frequent finding. EBUS-TBNA is a safe diagnostic approach to confirm SLL. Therefore, aggressive diagnostic approaches such as mediastinoscopy can be avoided. Still, both the prognostic and the immunologic impact of SLL in GCC remain unclear. Further studies should investigate the underlying biological mechanisms and the impact on prognosis.
Source: European Respiratory Journal - November 8, 2016 Category: Respiratory Medicine Authors: Schmidt, L., Lauterbach, B., Hansmeier, A., Hartig, I., Kessler, T., Schliemann, C., Schulze, A. B., Wardelmann, E., Pühse, G., Berdel, W., Wiewrodt, R., Mohr, M. Tags: 1.4 Interventional Pulmonology Source Type: research

Transcriptional blood signatures of sarcoidosis, sarcoid-like reactions and tubercolosis and their diagnostic implications.
Authors: Tchernev G, Chokoeva AA, Tana M, Tana C Abstract N/A. PMID: 27759000 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 21, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Subacute sarcoid myositis with ocular muscle involvement; a case report and review of the literature.
We describe a case of acute to subacute sarcoid myositis of the skeletal and extraocular muscles. Typical ophthalmic involvement (manifested by infiltration of the ocular adnexa, intraocular inflammation, or infiltration of the retrobulbar visual pathways) and extraocular sarcoid myositis (as with the present case) is infrequently reported. It is important to keep in mind the rare yet perhaps underestimated entity of sarcoid myositis, and to utilize muscle biopsy and imaging tests for appropriate diagnosis and management of patients with sarcoidosis. PMID: 27758998 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 21, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Pulmonary stenting for the treatment of sarcoid induced pulmonary vascular stenosis.
CONCLUSIONS: Pulmonary vascular stenosis from external compression can be a rare but unrecognized caused of worsening symptoms in advanced sarcoidosis. Pulmonary vascular angioplasty and stenting can provide clinical benefit in select patients. PMID: 27758995 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 21, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Extensive pulmonary sarcoid reaction in a patient with BMPR-2 associated idiopathic pulmonary arterial hypertension.
We describe a case of a 35-year-old woman with idiopathic pulmonary arterial hypertension (IPAH) and a novel BMPR2 mutation, who underwent a successful lung transplantation.  Extensive granulomatous inflammation was seen in the resected lungs. The granulomatous inflammation found in the histology supports  a sarcoid-like reaction due to pulmonary hypertension in the context of the BMPR2 mutation. PMID: 27537724 [PubMed - as supplied by publisher]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - August 19, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Pulmonary metastases from low grade sarcoma in a patient with pulmonary sarcoidosis. Sarcoidosis or sarcoid-like reaction?
Authors: Majori M, Anghinolfi M, Gnetti L, Casalini AG Abstract An asymptomatic man with previous histopatological diagnosis of pulmonary sarcoidosis in radiological follow-up (stable for about 4 years) presented massive right pleural effusion. After drainage, CT of the chest showed an increase in number and size of pulmonary nodules compared to the last check (8 months before). Surgical pulmonary biopsies were performed with the diagnosis of metastases from low grade sarcoma. The primary tumor was localized to the right buttock. Given the absence of symptoms, the extent of disease and many comorbidities the patien...
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - August 19, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Papular sarcoidosis of the knees. A frequent form of presentation of systemic sarcoidosis.
CONCLUSION: Papular sarcoidosis of the knees can be considered a relatively frequent form of cutaneous sarcoidosis usually present at the beginning of the disease that can be useful for the diagnosis of sarcoidosis. It is mainly observed in acute forms of sarcoidosis and can be considered a sign of good prognosis. PMID: 27055837 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 9, 2016 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Lung transplantation for pulmonary sarcoidosis. Twenty-five years of experience in the USA
Conclusions Recipients of lung transplants for pulmonary sarcoidosis had similar outcomes compared with non-sarcoid lung recipients.
Source: Thorax - March 14, 2016 Category: Respiratory Medicine Authors: Taimeh, Z., Hertz, M. I., Shumway, S., Pritzker, M. Tags: Epidemiologic studies, Interstitial lung disease, Cardiothoracic surgery, Transplantation Research letter Source Type: research

Propionibacterium acnes isolated from lymph nodes of patients with sarcoidosis.
We report two non-Japanese patients in whom mediastinoscopy was performed in order to obtain lymph node tissue for histopathology, which was suggestive for sarcoidosis. Bacterial culture of these uncontaminated mediastinal lymph nodes revealed P. acnes in both patients. As shown in these two cases, P. acnes can be isolated from sterile biopsied sarcoid lymph nodes of non-Japanese patients and supports the belief that there is an etiologic link between P. acnes sarcoidosis. Further elucidation could provide an opening to novel strategies using antibiotics for treating sarcoidosis. PMID: 26422574 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 3, 2015 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Sarcoid in cancer patients: clinical characteristics and associated disease status.
CONCLUSION:   While sarcoid often presents at initial diagnosis or staging of cancer, in a significant number of patients, it appears in association with recurrence or second malignancy. PMID: 26422564 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - October 3, 2015 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Cigarette smoking and male sex are independent and age concomitant risk factors for the development of ocular sarcoidosis in a New Orleans sarcoidosis population.
CONCLUSION: To date, there are few dedicated investigations of risk factors for OS, especially smoking. This investigation identified male sex, age, and tobacco exposure as independent risk factors for OS. Though disease duration did not withstand regression analysis in this moderately sized group, age at chart review suggests screening for OS should not remit but rather intensify in aging patients with sarcoidosis. (Sarcoidosis Vasc Diffuse Lung Dis 2015; 32: 183-143). PMID: 26278693 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - August 19, 2015 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Evaluation of Mediastinal Lymph Nodes in Sarcoidosis, Sarcoid Reaction, and Malignant Lymph Nodes Using CT and FDG-PET/CT
Abstract: The aim of this study was to analyze the clinical, computed tomography (CT), and positron emission tomography (PET) findings of sarcoidosis, sarcoid reaction, and malignant lymph nodes (LNs) to the results of transbronchial LN aspiration and biopsy (TBNA). The TBNA results of mediastinal and hilar LNs of 152 patients in our hospital from July 2008 to March 2013 were retrospectively reviewed. Two independent radiologists measured the size and attenuation of LNs on CT and assessed the probability of the 3 categories: sarcoidosis (n = 36), sarcoid reaction (n = 25), or malignant LNs (n = 91). The total v...
Source: Medicine - July 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Thyroid cancer & sarcoidosis.
CONCLUSION: Clinicians should be wary of this association/co-existence of SA and PTC to avoid mismanagement of neck lymphadenopathies in patients with current or history of SA. Although 4% of thyroid cancers may induce a sarcoid reaction in the thyroid gland, SA as a disease may coexist with PTC although causality remains uncertain. Being aware of this association is important in the differential diagnosis of a thyroid mass and/or a LN in a patient with SA. Therefore, patients with known SA who are found to have cervical adenopathies or thyroid nodules should have a thorough work up. PMID: 25363225 [PubMed - in process]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - November 25, 2014 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Recurrence of sarcoid granulomas in lung transplant recipients is common and does not affect overall survival.
Conclusions: Approximately 30% of lung transplant recipients due to sarcoidosis have recurrence of sarcoid granulomas. Recurrence of granulomas does not affect overall survival or lung function. PMID: 25078643 [PubMed - as supplied by publisher]
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - November 25, 2014 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Sarcoidosis or sarcoid-like reaction developed during the follow-up of malignant tumors: difficulties in differentiation from recurrent or metastatic diseases
Abstract Sarcoidosis or sarcoid-like reaction can occur or manifest several years after completion of treatment during the long-term follow-up of malignant tumors, often creating difficulty in differentiating these lesions from recurrent or metastatic malignant tumors on imaging studies. In recent years, CT and positron-emission tomography (PET) have been widely used in follow-up of malignant tumors; and findings in these studies are similar for sarcoidosis/sarcoid-like reaction and recurrent/metastatic diseases, special caution is needed in diagnosing either of these disorders. In patients who show results i...
Source: International Cancer Conference Journal - October 1, 2014 Category: Cancer & Oncology Source Type: research