This page shows you the latest news items in this category. This is page number 5.

Total 4939 results found since Jan 2013.

Clinical Trial to Assess the Safety of a Novel Scaffold Biomaterial
Conditions:   Peripheral Neuropathy;   Chronic Inflammatory Demyelinating Polyradiculoneuropathy;   Vasculitic Neuropathy (Disorder);   Amyloidosis;   Hereditary Neuropathy;   Sarcoid Neuropathy Interventions:   Device: Biopsy + Nerve Repair;   Procedure: Biopsy Only Sponsor:   Mayo Clinic Not yet recruiting
Source: ClinicalTrials.gov - July 12, 2018 Category: Research Source Type: clinical trials

Sarcoidosis: is cryobiopsy not cool enough? – Authors' reply
Publication date: Available online 11 July 2018Source: The Lancet Respiratory MedicineAuthor(s): Paolo Spagnolo, Giulio Rossi, Rocco Trisolini, Nicola Sverzellati, Robert P Baughman, Athol U Wells
Source: The Lancet Respiratory Medicine - July 12, 2018 Category: Respiratory Medicine Source Type: research

Sarcoidosis: is cryobiopsy not cool enough?
Publication date: Available online 11 July 2018Source: The Lancet Respiratory MedicineAuthor(s): Srinivas Rajagopala
Source: The Lancet Respiratory Medicine - July 12, 2018 Category: Respiratory Medicine Source Type: research

Are CT findings of pulmonary sarcoidosis ever sufficient for a presumptive diagnosis?
Publication date: Available online 11 July 2018Source: The Lancet Respiratory MedicineAuthor(s): David Naidich
Source: The Lancet Respiratory Medicine - July 12, 2018 Category: Respiratory Medicine Source Type: research

Clinical Trial to Assess the Safety of a Novel Scaffold Biomaterial
Conditions:   Peripheral Neuropathy;   Chronic Inflammatory Demyelinating Polyradiculoneuropathy;   Vasculitic Neuropathy (Disorder);   Amyloidosis;   Hereditary Neuropathy;   Sarcoid Neuropathy Interventions:   Device: Biopsy + Nerve Repair;   Procedure: Biopsy Only Sponsor:   Mayo Clinic Not yet recruiting
Source: ClinicalTrials.gov - July 12, 2018 Category: Research Source Type: clinical trials

The efficacy and safety of electroanatomic mapping-guided endomyocardial biopsy: a systematic review
ConclusionsEAM-guided EMB is a safe and efficacious method and might improve test characteristics over conventional fluoroscopy-guided biopsy.
Source: Journal of Interventional Cardiac Electrophysiology - July 12, 2018 Category: Cardiology Source Type: research

The Syndrome of Tubulointerstitial Nephritis With Uveitis (TINU)
This article begins with an illustrative case vignette, followed by an overview of the syndrome and current theories regarding its pathogenesis.
Source: American Journal of Kidney Diseases - July 11, 2018 Category: Urology & Nephrology Source Type: research

Value of 18-F-FDG PET/CT in assessment of patients with fever of unknown origin
Conclusion18F-FDG PET/CT can be a useful tool for scanning the whole body to suggest the FUO cause.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - July 11, 2018 Category: Nuclear Medicine Source Type: research

Urinary N-terminal fragment of titin is a marker to diagnose muscular dystrophy in patients with cardiomyopathy
Publication date: September 2018Source: Clinica Chimica Acta, Volume 484Author(s): Akiomi Yoshihisa, Takatoyo Kiko, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Yasuchika TakeishiAbstractThe differential diagnosis of cardiomyopathy is important. It has been recently reported that urinary titin N (U-TN) is increased in patients with muscular dystrophy (MD), and is associated with muscular damage. We aimed to clarify whether U-TN is useful as a diagnostic tool for distinguishing MD from various cardiomyopathies [e.g. dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM)]. We measured and compared the U-TN/cr...
Source: Clinica Chimica Acta - July 11, 2018 Category: Laboratory Medicine Source Type: research

Sarcoidosis from Head to Toe: What the Radiologist Needs to Know
RadioGraphics,Volume 38, Issue 4, Page 1180-1200, July-August 2018.
Source: Radiographics - July 11, 2018 Category: Radiology Authors: Dhakshinamoorthy Ganeshan Christine O. Menias Meghan G. Lubner Perry J. Pickhardt Kumaresan Sandrasegaran Sanjeev Bhalla Source Type: research

Pulmonary hypertension in patients with interstitial lung disease
Publication date: June 2018Source: Pulmonary Pharmacology & Therapeutics, Volume 50Author(s): Theodoros Karampitsakos, Argyrios Tzouvelekis, Serafeim Chrysikos, Demosthenes Bouros, Iraklis Tsangaris, Wassim H. FaresAbstractInterstitial lung diseases (ILDs) comprise a broad and heterogeneous group of more than two hundred diseases with common functional characteristics. Their diagnosis and management require a multidisciplinary approach. This multidisciplinary approach involves the assessment of comorbid conditions including pulmonary hypertension (PH) that exerts a dramatic impact on survival. The current World Health Orga...
Source: Pulmonary Pharmacology and Therapeutics - July 10, 2018 Category: Respiratory Medicine Source Type: research

Muscular sarcoidosis under anti-TNF treatment in ankylosing spondylitis
Publication date: Available online 19 May 2018Source: Joint Bone SpineAuthor(s): Daniel Wendling, Jean-Philippe Nueffer
Source: Joint Bone Spine - July 10, 2018 Category: Orthopaedics Source Type: research

Trident sign trumps Aquaporin-4-IgG ELISA in diagnostic value in a case of longitudinally extensive transverse myelitis
We report a case in which the patient was initially diagnosed with neuromyelitis optical spectrum disorder, but where the “trident” sign ultimately led to the correct diagnosis of spinal cord sarcoidosis.
Source: Multiple Sclerosis and Related Disorders - July 10, 2018 Category: Neurology Source Type: research

Symptomatic sarcoidosis with stomach, duodenum, small intestine and parotid gland involvement
Publication date: Available online 18 June 2018Source: Clinics and Research in Hepatology and GastroenterologyAuthor(s): Jianxiong Zhang, Haoyan Wang, Rui Xu, Guangyong Chen, Yongdong Wu, Ming Ji, Shutian Zhang, Haiying Zhao
Source: Clinics and Research in Hepatology and Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research

Severe Myocardial Fibrosis After Sarcoid Inflammation
Publication date: July 2018Source: Revista Española de Cardiología (English Edition), Volume 71, Issue 7Author(s): Mario Sutil-Vega, Daniel Romeu Vilar, Eulàlia Roig
Source: Revista Espanola de Cardiologia - July 10, 2018 Category: Cardiology Source Type: research

Left ventricular myocardial calcifications and its impact on cardiovascular prognosis
ConclusionLeft ventricle MC is very rare. The dystrophic MC from ischemic origin is the most frequent. At long-term follow-up, 59% of MC had altered LVEF, it is more frequent (80%) in I-MC. The extent of LV MC was associated with high risk of cardiac death and ventricular arrhythmia.
Source: Archives of Cardiovascular Diseases Supplements - July 10, 2018 Category: Cardiology Source Type: research

Contribution of 11C-Choline PET/CT in prostate carcinoma biochemical relapse with serum PSA level below 1 ng/ml
Conclusions11C-Choline PET/CT proved its usefulness in demonstrating tumour in 14% of patients with BR of PCa and serum PSA <1 ng/ml, with therapeutic implications. In 4% of patients a benign condition was detected. A normal 11C-Choline PET/CT was associated with a very low rate of recurrence at 30 months.ResumenObjetivoLa PET/TC con 11C-colina ha mostrado buenos resultados en la reestadificación del cáncer de próstata (CP) con antígeno específico prostático (PSA) elevado. Su uso con niveles bajos es controvertido. Nuestro objetivo fue evaluar la aportación de la 11C-colina PET/TC en pacientes con CP, recid...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - July 10, 2018 Category: Nuclear Medicine Source Type: research

18F-FDG PET/CT helps in unmasking the great mimicker: A case of neurosarcoidosis with isolated involvement of the spinal cord
Publication date: May–June 2018Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), Volume 37, Issue 3Author(s): A. Gholamrezanezhad, L. MehtaAbstractA 36 year-old male with no significant past medical history presented with lower extremity numbness, gait instability, and urinary and bowel retention of 4 weeks onset. Spine MRI revealed diffuse oedema of cervicothoracic spinal cord with several solid enhancing intramedullary lesions, suggestive of metastases. The 18F-FDG PET/CT performed to identify the primary malignancy demonstrated mild hypermetabolic foci within the cervicothoracic cord,...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - July 10, 2018 Category: Nuclear Medicine Source Type: research

In Situ Humoral Immunity to Vimentin in HLA-DRB1*03+ Patients With Pulmonary Sarcoidosis
Andrew J. Kinloch, Ylva Kaiser, Don Wolfgeher, Junting Ai, Anders Eklund, Marcus R. Clark, Johan Grunewald
Source: Frontiers in Immunology - July 9, 2018 Category: Allergy & Immunology Source Type: research

Cerebrovascular Manifestations of Neurosarcoidosis: An Underrecognized Aspect of the Imaging Spectrum ADULT BRAIN
SUMMARY: Involvement of the central nervous system by sarcoidosis, also referred to as neurosarcoidosis, is seen clinically in about 5% of patients with systemic disease. CNS involvement most frequently affects the leptomeninges and cranial nerves, though the ventricular system, brain parenchyma, and pachymeninges may also be involved. Even though the involvement of the intracranial vascular structures is well-known on postmortem studies, there is scant literature on imaging manifestations secondary to the vessel wall involvement, being confined mostly to isolated case reports and small series. The authors present a review...
Source: American Journal of Neuroradiology - July 9, 2018 Category: Radiology Authors: Bathla, G., Watal, P., Gupta, S., Nagpal, P., Mohan, S., Moritani, T. Tags: ADULT BRAIN Source Type: research

Metastatic sigmoid colon adenocarcinoma and tumour ‐related sarcoid reaction
Internal Medicine Journal,Volume 48, Issue 7, Page 876-878, July 2018.
Source: Internal Medicine Journal - July 9, 2018 Category: Internal Medicine Authors: Michael De Gregorio , Andrew J. Brett Source Type: research

Tropical Travel Trouble 009 Humongous HIV Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with a low ...
Source: Life in the Fast Lane - July 7, 2018 Category: Emergency Medicine Authors: Amanda McConnell Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs

Treatment of Chronic Pulmonary Aspergillosis: Current Standards and Future Perspectives
Chronic pulmonary aspergillosis (CPA) complicates conditions including tuberculosis, chronic obstructive pulmonary disease and sarcoidosis, and is associated with high morbidity and mortality. Surgical cure should be considered where feasible; however, many patients are unsuitable for surgery due to extensive disease or poor respiratory function. Azoles are the only oral drug with anti-Aspergillus activity and itraconazole and voriconazole are considered as first-line drugs. A randomized controlled trial demonstrated improvement or stability in three-quarters of patients given 6 months of itraconazole, but a quarter relaps...
Source: Respiration - July 6, 2018 Category: Respiratory Medicine Source Type: research

The Syndrome of Tubulointerstitial Nephritis With Uveitis (TINU)
This article begins with an illustrative case vignette, followed by an overview of the syndrome and current theories regarding its pathogenesis.
Source: American Journal of Kidney Diseases - July 5, 2018 Category: Urology & Nephrology Source Type: research

Pulmonary hypertension in patients with interstitial lung disease
Publication date: June 2018Source: Pulmonary Pharmacology & Therapeutics, Volume 50Author(s): Theodoros Karampitsakos, Argyrios Tzouvelekis, Serafeim Chrysikos, Demosthenes Bouros, Iraklis Tsangaris, Wassim H. FaresAbstractInterstitial lung diseases (ILDs) comprise a broad and heterogeneous group of more than two hundred diseases with common functional characteristics. Their diagnosis and management require a multidisciplinary approach. This multidisciplinary approach involves the assessment of comorbid conditions including pulmonary hypertension (PH) that exerts a dramatic impact on survival. The current World Health Orga...
Source: Pulmonary Pharmacology and Therapeutics - July 5, 2018 Category: Respiratory Medicine Source Type: research

Muscular sarcoidosis under anti-TNF treatment in ankylosing spondylitis
Publication date: Available online 19 May 2018Source: Joint Bone SpineAuthor(s): Daniel Wendling, Jean-Philippe Nueffer
Source: Joint Bone Spine - July 5, 2018 Category: Orthopaedics Source Type: research

Trident sign trumps Aquaporin-4-IgG ELISA in diagnostic value in a case of longitudinally extensive transverse myelitis
We report a case in which the patient was initially diagnosed with neuromyelitis optical spectrum disorder, but where the “trident” sign ultimately led to the correct diagnosis of spinal cord sarcoidosis.
Source: Multiple Sclerosis and Related Disorders - July 5, 2018 Category: Neurology Source Type: research

Symptomatic sarcoidosis with stomach, duodenum, small intestine and parotid gland involvement
Publication date: Available online 18 June 2018Source: Clinics and Research in Hepatology and GastroenterologyAuthor(s): Jianxiong Zhang, Haoyan Wang, Rui Xu, Guangyong Chen, Yongdong Wu, Ming Ji, Shutian Zhang, Haiying Zhao
Source: Clinics and Research in Hepatology and Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research

Severe Myocardial Fibrosis After Sarcoid Inflammation
Publication date: July 2018Source: Revista Española de Cardiología (English Edition), Volume 71, Issue 7Author(s): Mario Sutil-Vega, Daniel Romeu Vilar, Eulàlia Roig
Source: Revista Espanola de Cardiologia - July 5, 2018 Category: Cardiology Source Type: research

Left ventricular myocardial calcifications and its impact on cardiovascular prognosis
ConclusionLeft ventricle MC is very rare. The dystrophic MC from ischemic origin is the most frequent. At long-term follow-up, 59% of MC had altered LVEF, it is more frequent (80%) in I-MC. The extent of LV MC was associated with high risk of cardiac death and ventricular arrhythmia.
Source: Archives of Cardiovascular Diseases Supplements - July 5, 2018 Category: Cardiology Source Type: research

Contribution of 11C-Choline PET/CT in prostate carcinoma biochemical relapse with serum PSA level below 1 ng/ml
Conclusions11C-Choline PET/CT proved its usefulness in demonstrating tumour in 14% of patients with BR of PCa and serum PSA <1 ng/ml, with therapeutic implications. In 4% of patients a benign condition was detected. A normal 11C-Choline PET/CT was associated with a very low rate of recurrence at 30 months.ResumenObjetivoLa PET/TC con 11C-colina ha mostrado buenos resultados en la reestadificación del cáncer de próstata (CP) con antígeno específico prostático (PSA) elevado. Su uso con niveles bajos es controvertido. Nuestro objetivo fue evaluar la aportación de la 11C-colina PET/TC en pacientes con CP, recid...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - July 5, 2018 Category: Nuclear Medicine Source Type: research

18F-FDG PET/CT helps in unmasking the great mimicker: A case of neurosarcoidosis with isolated involvement of the spinal cord
Publication date: May–June 2018Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), Volume 37, Issue 3Author(s): A. Gholamrezanezhad, L. MehtaAbstractA 36 year-old male with no significant past medical history presented with lower extremity numbness, gait instability, and urinary and bowel retention of 4 weeks onset. Spine MRI revealed diffuse oedema of cervicothoracic spinal cord with several solid enhancing intramedullary lesions, suggestive of metastases. The 18F-FDG PET/CT performed to identify the primary malignancy demonstrated mild hypermetabolic foci within the cervicothoracic cord,...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - July 5, 2018 Category: Nuclear Medicine Source Type: research

Value of 18-F-FDG PET/CT in assessment of patients with fever of unknown origin
Conclusion18F-FDG PET/CT can be a useful tool for scanning the whole body to suggest the FUO cause.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - July 5, 2018 Category: Nuclear Medicine Source Type: research

A cavernous sinus lesion clinically responsive to steroids
We describe a patient presenting with neurologic symptoms referable to a persistent unilateral cavernous sinus MRI abnormality, initially thought to be consistent with Tolosa-Hunt syndrome, that was clinically but not radiographically responsive to steroids. Following reevaluation due to the presence of new symptoms, pathology revealed that the abnormality was most consistent with chordoma, a rare skull based tumor. In patients with a presumed diagnosis of Tolosa-Hunt syndrome, close clinical and radiographic follow-up is imperative, with early consideration for biopsy in patients that fail to respond to treatment both cli...
Source: Journal of Clinical Neuroscience - July 5, 2018 Category: Neuroscience Source Type: research

Urinary N-terminal fragment of titin is a marker to diagnose muscular dystrophy in patients with cardiomyopathy
Publication date: September 2018Source: Clinica Chimica Acta, Volume 484Author(s): Akiomi Yoshihisa, Takatoyo Kiko, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Yasuchika TakeishiAbstractThe differential diagnosis of cardiomyopathy is important. It has been recently reported that urinary titin N (U-TN) is increased in patients with muscular dystrophy (MD), and is associated with muscular damage. We aimed to clarify whether U-TN is useful as a diagnostic tool for distinguishing MD from various cardiomyopathies [e.g. dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM)]. We measured and compared the U-TN/cr...
Source: Clinica Chimica Acta - July 5, 2018 Category: Laboratory Medicine Source Type: research

Physicochemical characterization of inorganic deposits associated with granulomas in cutaneous sarcoidosis
Journal of the European Academy of Dermatology and Venereology,Volume 0, Issue ja, -Not available-.
Source: Journal of the European Academy of Dermatology and Venereology - July 4, 2018 Category: Dermatology Authors: H. Colboc , P. Moguelet , D. Bazin , C. Bachmeyer , V. Frochot , R. Weil , E. Letavernier , C. Jouanneau , M. Daudon , J.F. Bernaudin Source Type: research

Is 18 F-FDG PET/CT useful for the differential diagnosis of solitary pulmonary nodules in patients with idiopathic pulmonary fibrosis?
Conclusions18F-FDG PET/CT is useful for differentiating benign and malignant SPNs in patients with IPF, as it is for patients without IPF.
Source: Annals of Nuclear Medicine - July 4, 2018 Category: Nuclear Medicine Source Type: research

Endobronchial Ultrasound-guided Transbronchial Needle Aspiration With a 19-G Needle Device
Conclusions: A new flexible 19-G EBUS needle was successfully and safely applied in a large patient cohort for sampling of lung and enlarged mediastinal lesions with high diagnostic rates across clinical indications.
Source: Journal of Bronchology and Interventional Pulmonology - July 1, 2018 Category: Respiratory Medicine Tags: Original Investigations Source Type: research

Characteristics, outcome and treatments with cranial pachymeningitis: A multicenter French retrospective study of 60 patients
The aim of this study was to determine the characteristics, treatment, and outcome according to each etiology of pachymeningitis. We conducted a retrospective multicenter French nationwide study between 2000 and 2016 to describe the characteristics, outcome, and treatment of pachymeningitis. We included 60 patients (median age 55.5 years; interquartile range [IQR] 30–80, female/male ratio 0.43). Neurologic signs were present in 59 patients (98%) and consisted of headache in 43 (72%), cranial nerve palsy in 33 (55%), confusion in 10 (17%), seizures in 7 (12%), and focal neurologic signs in 9 (15%). Fever and weight loss...
Source: Medicine - July 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research