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A Retrospective Study of Korean Adults With Food Allergy: Differences in Phenotypes and Causes.
CONCLUSIONS: The major causes of FA in Korean adults were crustacean, fruits, and grains. Interestingly, the clinical manifestations of FA and demographics varied according to type of food allergen. PMID: 28913993 [PubMed]
Source: Allergy, Asthma and Immunology Research - September 17, 2017 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

American College of Allergy, Asthma & Immunology Position Paper on the Use of Telemedicine for Allergists.
This article serves to offer policy and position statements of the use of telemedicine pertinent to the allergy and immunology subspecialty. PMID: 29103799 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - November 2, 2017 Category: Allergy & Immunology Authors: Elliott T, Shih J, Dinakar C, Portnoy J, Fineman S Tags: Ann Allergy Asthma Immunol Source Type: research

Systemic IL ‐2/anti‐IL‐2Ab complex combined with sublingual immunotherapy suppresses experimental food allergy in mice through induction of mucosal regulatory T cells
In conclusion, the combination of two therapeutic strategies rendered Treg‐mediated tolerance more efficient compared to individual treatments and reversed the established IgE‐mediated food allergy. This approach highlights the ability of IL‐2C to expand Tregs, and it may represent a promising disease‐modifying therapy for managing food allergy. This article is protected by copyright. All rights reserved.
Source: Allergy - January 10, 2018 Category: Allergy & Immunology Authors: Paola L. Smaldini, Fernando Trejo, Jos é L Cohen, Eliane Piaggio, Guillermo H. Docena Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Allergy and high trait anxiety are related to increases in heart rate variability: results of naturalistic long-term design study.
This study investigated HRV of 20 low anxious allergic, 19 healthy high trait anxious and 18 healthy low anxious, in naturalistic setting. On arranged research days, subjects performed measurements using portable ECG device and subjective self-assessment of perceived stress. Five repeated measurements data from each subject have shown increases in overall HRV, as well as HRV on respiratory frequencies in both allergy and high trait anxiety. Subject's sex was an important factor, because HRV increases in allergy were only apparent in women. Data from self-assessment show no differences in experienced stress attributable to ...
Source: European Annals of Allergy and Clinical Immunology - January 21, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Local anesthetics allergy: who should be tested?
Conclusion. The most common referral reason for testing with LA was a history of DHR to drugs other than LAs, whereas asthma was the third most common referral reason. Patients with a history of multiple DHR may be considered for testing with LAs. Asthmatics and those with other allergic diseases without a history of drug / LA allergy do not need to be tested with LA. PMID: 29384109 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - February 2, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

How to diagnose food allergy
Purpose of review To assess the recent studies that focus on specific immunoglobulin E (sIgE) testing and basophil activation test (BAT) for diagnosing IgE-mediated food allergies. Recent findings The sIgE to allergen extract or component can predict reactivity to food. The cutoff value based on the positive predictive value (PPV) of sIgE can be considered whenever deciding whether oral food challenge (OFC) is required to diagnose hen's egg, cow's milk, wheat, peanut, and cashew nut allergy. However, PPV varies depending on the patients’ background, OFC methodology, challenge foods, and assay methodology. Component-...
Source: Current Opinion in Allergy and Clinical Immunology - April 26, 2018 Category: Allergy & Immunology Tags: FOOD ALLERGY: Edited by Alessandro Fiocchi and Motohiro Ebisawa Source Type: research

The role of gastrointestinal permeability in food allergy.
CONCLUSIONS: A functional gastrointestinal barrier is of paramount importance to prevent immunologically mediated food hypersensitive reactions. PMID: 29803708 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 24, 2018 Category: Allergy & Immunology Authors: Samadi N, Klems M, Untersmayr E Tags: Ann Allergy Asthma Immunol Source Type: research

Is There Any Necessity to Prescribe Consumption of Walnuts Cooked by Different Processing Techniques to Patients With Walnut Allergy?
Authors: Oh JW Abstract The present study focused on identifying the usual methods of cooking walnuts in order to investigate changes in walnut allergen activity caused by cooking and evaluated the allergenic changes in walnut proteins within raw, dry-fried and boiled walnuts. Previous studies have reported a decrease in the allergen activity of walnut by thermal processing methods, which are not used in Korean kitchens, such as dry-frying and boiling. In Korea, Walnuts are consumed with rice and usually boiled and stir-fried with seasoning. Thus, the present study clarified the protein bands corresponding to raw w...
Source: Allergy, Asthma and Immunology Research - June 28, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Mechanisms by Which Atopic Dermatitis Predisposes to Food Allergy and the Atopic March.
Authors: Tham EH, Leung DY Abstract The Atopic march denotes the progression from atopic dermatitis (AD) to the development of other allergic disorders such as immunoglobulin (Ig) E-mediated food allergy, allergic rhinitis and asthma in later childhood. There is increasing evidence from prospective birth cohort studies that early-onset AD is a risk factor for other allergic diseases or is found in strong association with them. Animal studies now provide mechanistic insights into the pathways that may be responsible for triggering the progression from the skin barrier dysfunction seen in AD to epicutaneous sensitiza...
Source: Allergy, Asthma and Immunology Research - November 29, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Adenovirus-mediated Gene Therapy for Allergy.
Abstract Allergy poses a heavy health burden in modern society. Other than symptom-relieving medications, the only available treatment approach is allergen-specific immunotherapy, which in spite of offering a potential cure, requires a long treatment duration with multiple doses of allergen administration and carries a risk of anaphylaxis. Gene therapy has shown advantages in experimental studies for treatment of tumors, genetic diseases, chronic infections, and allergy. To date, adenovirus has been the most extensively used gene transfer vector, and offers high efficiency and safety. Here, we review studies of ad...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 1, 2018 Category: Allergy & Immunology Authors: Ma S, Guan J Tags: Iran J Allergy Asthma Immunol Source Type: research

Occupational food allergy
Purpose of review Occupation is an important contributing factor in the presentation of allergic disease in adults. This review article focuses on the contribution of occupation to the development and presentation of food allergies. Recent findings A variety of occupations involve repeated transdermal and respiratory exposures to food-related allergens, which can result in sensitization. A sensitized individual can then manifest symptoms of food allergy after ingestion of the relevant food, even in a nonoccupational setting. Cooks and other food-processing workers bear increased risk for being sensitized to foods. Alt...
Source: Current Opinion in Allergy and Clinical Immunology - April 30, 2019 Category: Allergy & Immunology Tags: FOOD ALLERGY: Edited by Alessandro Fiocchi and Motohiro Ebisawa Source Type: research

Gender aspects in food allergy
Purpose of review The difference of food allergy prevalence between male and female individuals is well documented and should have more impact for personalized diagnosis and management. Although in younger age male sex dominates, in adults more women are affected by food allergies. This sex disparity diminishes again around menopause, underlining the influence of sex hormones, but in addition, also metabolic gender-specific factors and differences in microbiome composition might contribute to the different expression of food allergy in the two genders. The sex-dependent and gender-dependent influence on development of fo...
Source: Current Opinion in Allergy and Clinical Immunology - April 30, 2019 Category: Allergy & Immunology Tags: FOOD ALLERGY: Edited by Alessandro Fiocchi and Motohiro Ebisawa Source Type: research

Atopic dermatitis and its relation to food allergy
Purpose of review To present the most recent evidence on atopic dermatitis and its relation to food allergy. Recent findings Atopic dermatitis is a chronic inflammatory disorder of the skin characterized by impaired skin barrier because of multifactorial causes including genetic factors, immune dysregulation, and skin microbiome dysbiosis. Infants with temporary skin barrier disruption and/or persistent atopic dermatitis are particularly at risk of developing food allergy (during the so-called atopic march), with up to half of patients demonstrating positive food-specific IgE and one-third of severe cases of atopic de...
Source: Current Opinion in Allergy and Clinical Immunology - May 1, 2020 Category: Allergy & Immunology Tags: FOOD ALLERGY: Edited by Alessandro Fiocchi and Motohiro Ebisawa Source Type: research

Iranian Society of Asthma and Allergy Codes of Professional Ethics.
Abstract The advances in science and technology in recent decades, especially in medical sciences, have raised new ethical challenges. Hence, professional organizations in the field of medical science are trying to develop regulations in the field of medical ethics to help medical science professionals in making the best decisions in different circumstances and moral dilemmas. The organizations also try to monitor their performance using those regulations. On the other hand, due to the specialization of medical science as well as the complexity of communication between these disciplines, there is a growing need fo...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 15, 2020 Category: Allergy & Immunology Authors: Shamsi-Gooshki E, Ahmadi Pishkuhi M, Mousavi MS, Raoofi A, Fazlollahi MR, Parsapour A, Moin M Tags: Iran J Allergy Asthma Immunol Source Type: research

Forty Years of Research and Treatment in Immunology and Allergy: In Honor of Professor Reza Farid Hosseini.
Abstract In light of various supports of prodigious figures in the field of immunology and allergy, the subject area has been faced a great leap during the last century. The current state of the discipline owes an abundant appreciation for the scholars motivated in escalating the true nature of the science, who left no stone unturned in improving the general common sense and understanding of the human knowledge in general, and immunology and allergy in particular. Professor Reza Farid Hosseini is among the dignitaries who invested his life and energy on weaving the tapestry of the immunology and allergy. He delive...
Source: Iranian Journal of Allergy, Asthma and Immunology - May 16, 2020 Category: Allergy & Immunology Authors: Jafari R, Moin M, Kashanchi F, Rajbar A Tags: Iran J Allergy Asthma Immunol Source Type: research