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Factors associated with reported food allergy tolerance among US children.
CONCLUSION: Multiple factors were associated with a report of outgrowing an allergy. Understanding factors associated with outgrowing an allergy can improve disease management and counseling. PMID: 23987195 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - September 1, 2013 Category: Allergy & Immunology Authors: Gupta RS, Lau CH, Sita EE, Smith B, Greenhawt MJ Tags: Ann Allergy Asthma Immunol Source Type: research

The natural history and clinical predictors of egg allergy in the first 2 years of life: A prospective, population-based cohort study
Conclusion: Phenotyping of egg allergy (baked egg tolerant vs allergic) should be considered in the management of this allergy because it has prognostic implications and eases dietary restrictions. Randomized controlled trials for egg oral immunotherapy should consider stratifying at baseline by the baked egg subphenotype to account for the differential rate of tolerance development.
Source: Journal of Allergy and Clinical Immunology - December 27, 2013 Category: Allergy & Immunology Authors: Rachel L. Peters, Shyamali C. Dharmage, Lyle C. Gurrin, Jennifer J. Koplin, Anne-Louise Ponsonby, Adrian J. Lowe, Mimi L.K. Tang, Dean Tey, Marnie Robinson, David Hill, Helen Czech, Leone Thiele, Nicholas J. Osborne, Katrina J. Allen, HealthNuts study Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research

History of food allergy.
Authors: Wüthrich B Abstract In this chapter we will first consider whether there is real evidence on the basis of literature for early descriptions in antiquity of pathogenic reactions after food intake that could be comparable to allergy, for instance in the scriptures of Hippocrates or Lucretius. On this topic we are skeptical, which is in agreement with the medical historian Hans Schadewaldt. We also assert that it is unlikely that King Richard III was the first food-allergic individual in medical literature. Most probably it was not a well-planned poisoning ('allergy') with strawberries, but rather a birth de...
Source: Chemical Immunology and Allergy - December 2, 2014 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants.
Agache I, Akdis CA, Arshad H, Beyer K, Dubois A, Eigenmann P, Fernandez-Rivas M, Grimshaw K, Hoffman-Sommergruber K, Host A, Lau S, O'Mahony L, Mills C, Papadopoulos N, Venter C, Agmon-Levin N, Kessel A, Antaya R, Drolet B, Rosenwasser L Abstract The purpose of this brief communication is to highlight emerging evidence to existing guidelines regarding potential benefits of supporting early, rather than delayed, peanut introduction during the period of complementary food introduction in infants. This document should be considered as interim guidance based on consensus among the following organizations: American Ac...
Source: Annals of Allergy, Asthma and Immunology - June 27, 2015 Category: Allergy & Immunology Authors: Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Muraro A, Halken S, Katz Y, Ebisawa M, Eichenfield L, Sampson H, Lack G, Du Toit G, Roberts G, Bahnson H, Feeney M, Hourihane J, Spergel J, Young M, As'aad A, Allen K, Prescott S, Kapur S, Saito H Tags: Ann Allergy Asthma Immunol Source Type: research

Factors associated with the course of egg allergy in children.
CONCLUSION: Baseline egg white sIgE levels, baseline gastrointestinal system involvement, concomitant cow's milk allergy, and anaphylaxis with egg may predict a more severe course of egg allergy with late resolution. Moreover, egg white sIgE levels and gastrointestinal symptoms after egg exposure seem to increase the risk of anaphylaxis with egg. PMID: 26505933 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - October 31, 2015 Category: Allergy & Immunology Authors: Arik Yilmaz E, Cavkaytar O, Buyuktiryaki B, Sekerel BE, Soyer O, Sackesen C Tags: Ann Allergy Asthma Immunol Source Type: research

Evaluating a handbook for parents of children with food allergy: a randomized clinical trial.
CONCLUSIONS: The food allergy handbook evaluated in this study is an effective parent resource to supplement physician management of food allergy. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT01914978. PMID: 26851890 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - February 3, 2016 Category: Allergy & Immunology Authors: LeBovidge JS, Michaud A, Deleon A, Harada L, Waserman S, Schneider L Tags: Ann Allergy Asthma Immunol Source Type: research

Wheat allergy: diagnosis and management
Antonella Cianferoni Department of Pediatrics, Division of Allergy and Immunology, The Children’s Hospital of Philadelphia, PA, USA Abstract: Triticum aestivum (bread wheat) is the most widely grown crop worldwide. In genetically predisposed individuals, wheat can cause specific immune responses. A food allergy to wheat is characterized by T helper type 2 activation which can result in immunoglobulin E (IgE) and non-IgE mediated reactions. IgE mediated reactions are immediate, are characterized by the presence of wheat-specific IgE antibodies, and can be life-threatening. Non-IgE mediated reactions are characterized ...
Source: Journal of Asthma and Allergy - January 28, 2016 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

Pattern of inpatient referrals to a drug allergy unit in Kuwait.
Conclusion. Inpatient drug allergy referrals are highly underreported in Kuwait. PMID: 29249136 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - December 19, 2017 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Preliminary psychometric analyses and clinical performance of a caregiver self-efficacy scale for food allergy self-management.
CONCLUSION: We present preliminary evidence the FASEQ is a valid tool to assess caregiver food allergy self-efficacy. Self-efficacy is a distinct but related concept that captures aspects of self-management that are an important companion to health-related quality of life. PMID: 29273132 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - December 25, 2017 Category: Allergy & Immunology Authors: Greenhawt M, DunnGalvin A Tags: Ann Allergy Asthma Immunol Source Type: research

Oral allergy syndrome.
CONCLUSION: Patients with grass allergy may have a response to peaches, oranges, celery, tomatoes, and melons. Patients with ragweed allergy may show OAS symptoms with melon, cucumber, banana, and zucchini. Physicians should be aware of OAS and know the appropriate treatment. PMID: 29336286 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2018 Category: ENT & OMF Authors: Muluk NB, Cingi C Tags: Am J Rhinol Allergy Source Type: research

Improving allergy office scheduling increases patient follow up and reduces asthma readmission after pediatric asthma hospitalization.
CONCLUSION: This data suggests that minor changes in allergy practice organization can significantly affect post-hospitalization follow-up rates and decrease asthma readmission rates. PMID: 30170026 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - August 28, 2018 Category: Allergy & Immunology Authors: Ruffner MA, Henrickson SE, Chilutti M, Grundmeier R, Spergel JM, Brown-Whitehorn TF Tags: Ann Allergy Asthma Immunol Source Type: research

Review Article: Unmet needs of children with peanut allergy: aligning the risks and the evidence.
CONCLUSION: There are significant unmet needs in our understanding of peanut allergy; addressing these needs will help to enhance understanding of how to most effectively prevent and treat peanut allergy, as well as educate the food-allergic and nonallergic community regarding current evidence-based practices. PMID: 32007568 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - January 29, 2020 Category: Allergy & Immunology Authors: Chan ES, Dinakar C, Gonzales-Reyes E, Green TD, Gupta R, Jones D, Wang J, Winders T, Greenhawt M Tags: Ann Allergy Asthma Immunol Source Type: research

Food Allergy in At- Risk Adolescents with Asthma: A Key Area for Focus.
CONCLUSION: Food allergy is common among this cohort of asthmatic adolescents. While food allergy was not related to asthma symptom severity, food allergic adolescents had higher FeNo and more activity limitation, and the majority did not have epinephrine auto-injectors. A history of food allergy and lack of epinephrine autoinjector may increase near fatal outcomes in adolescents with asthma. Preventive measures in addition to standard asthma treatments are warranted for these teens. PMID: 32534023 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - June 9, 2020 Category: Allergy & Immunology Authors: Stern J, Chen M, Jusko TA, Fagnano M, Järvinen KM, Halterman JS Tags: Ann Allergy Asthma Immunol Source Type: research

Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization.
CONCLUSIONS: CHI3L1 plays a pivotal role in Th2 inflammation and M2 macrophage polarization through MAPK/ERK and PI3K/AKT phosphorylation in food allergy. PMID: 32935492 [PubMed]
Source: Allergy, Asthma and Immunology Research - September 18, 2020 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Piperacillin-Tazobactam Allergies: An Exception to Usual Penicillin Allergy.
CONCLUSIONS: There is growing utilization of PT and corresponding cases of suspected allergies. The majority of suspected PT allergies had increased risk for recurrent infections. Unlike other penicillin allergy, there is a high rate of genuine PT allergy (up to 30%) and a poor NPV of ST (up to 70%). DPT remains the gold standard for accurate diagnosis, and all patients with a suspected allergy should undergo thorough allergy workup. PMID: 33474862 [PubMed]
Source: Allergy, Asthma and Immunology Research - January 23, 2021 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research