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Year in review: pediatric allergy and asthma, excluding food allergy.
PMID: 25744902 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - March 1, 2015 Category: Allergy & Immunology Authors: Hauptman M, Phipatanakul W Tags: Ann Allergy Asthma Immunol Source Type: research

Attenuation of food allergy symptoms following treatment with human milk oligosaccharides in a mouse model
ConclusionsOur results suggest that 2’ Fucosylactose and 6’ Sialyllactose reduce the symptoms of food allergy through induction of IL‐10+ T regulatory cells and indirect stabilization of mast cells. Thus, human milk oligosaccharides may have therapeutic potential in allergic disease.This article is protected by copyright. All rights reserved.
Source: Allergy - May 13, 2015 Category: Allergy & Immunology Authors: Lucrecia Castillo ‐Courtade, SangSu Han, Sojeong Lee, Firoz M Mian, Rachael Buck, Paul Forsythe Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Nutritional aspects and diets in food allergy.
Authors: Nowak-Węgrzyn A, Groetch M Abstract Dietary intervention is a crucial component of food allergy management but can negatively impact nutrient intake. A comprehensive nutrition assessment with appropriate intervention is warranted in all children with food allergies to meet nutrient needs and optimize growth. Nutrition assessment may also be indicated in adults with food allergy. Frequently, an elimination diet is absolutely necessary to prevent potentially life-threatening anaphylaxis. Allergen elimination can also improve chronic symptoms, such as atopic dermatitis, when a food is proven to trigger sympt...
Source: Chemical Immunology and Allergy - May 31, 2015 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

Anaphylaxis in food allergy.
Authors: Pesek RD, Jones SM Abstract Food allergy is a known trigger of anaphylaxis. Although the awareness of food allergies has improved, food-related allergic reactions and anaphylaxis still commonly occur. The recognition of anaphylaxis, its prompt treatment, and patient education are important for the prevention of future food reactions. Patients and health care providers should also recognize the importance of epinephrine as the primary treatment of anaphylaxis. When food-related anaphylaxis occurs, patients should receive education regarding their food allergies, an epinephrine auto-injector, and follow-up w...
Source: Chemical Immunology and Allergy - May 31, 2015 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

Atopic eczema and food allergy.
Authors: Wassmann A, Werfel T Abstract Approximately one-third of children with severe atopic eczema suffer from a food allergy, whereas in adult patients, food allergies are rare. In child patients, three different clinical reaction patterns can be differentiated as follows: (1) immediate-type reactions, (2) isolated late eczematous reactions, and (3) combined immediate-type and late eczematous reactions. In childhood food allergies, food allergens, such as cow's milk or hen's egg, are primarily responsible for allergic reactions, while in adolescents and adults, food allergies often develop consecutively after pr...
Source: Chemical Immunology and Allergy - May 31, 2015 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

IgE-Related Examination in Food Allergy with Focus on Allergen Components.
Authors: Borres MP, Sato S, Ebisawa M Abstract Molecular allergology is a breakthrough science that enables the quantification of IgE antibodies against individual allergen protein components at the molecular level. The diagnosis of IgE-mediated allergic disorders is based on the clinical history and on sensitization demonstrated through an allergy test. Identifying whether the sensitization is primary (species specific) or due to cross-reactivity with proteins with similar protein structures helps the clinician to judge the risk of allergic reaction. This is possible today because allergen component tests for food...
Source: Chemical Immunology and Allergy - May 31, 2015 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

Mugwort-fennel-allergy-syndrome associated with sensitization to an allergen homologous to Api g 5.
CONCLUSION: A 60 kDa allergen, highly homologous to Api g 5, was recognized in fennel by patient's IgE. Inhibition experiments showed a high degree of cross-reactivity between this fennel allergen and the homologous mugwort pollen allergen. This allergen might be responsible for the mugwort-celery-spice syndrome. PMID: 24067338 [PubMed - indexed for MEDLINE]
Source: European Annals of Allergy and Clinical Immunology - August 2, 2015 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Decreased FOXP3 mRNA expression in children with atopic asthma and IgE-mediated food allergy.
CONCLUSION: Significantly lower levels of FOXP3 gene expression, observed more commonly in children with asthma and IgE-dependent FA than in healthy controls, were associated with a more severe clinical course. Therefore, FOXP3 expression could serve as an indicator of severe asthma with concomitant atopic conditions such as IgE-dependent FA. PMID: 26409874 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - September 22, 2015 Category: Allergy & Immunology Authors: Krogulska A, Polakowska E, Wąsowska-Królikowska K, Małachowska B, Młynarski W, Borowiec M Tags: Ann Allergy Asthma Immunol Source Type: research

One-year survey of paediatric anaphylaxis in an allergy department.
CONCLUSIONS: In our paediatric population, the main triggering agent of anaphylaxis was IgE-mediated food allergy. Epinephrine is underused, as reported by others. Often, children have several episodes before being assessed by an allergist. We stress the importance of systematic notification and improvement of educational programmes in order to achieve a better preventive and therapeutic management of this life-threatening entity. PMID: 26549337 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - November 11, 2015 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Rush immunotherapy for wasp venom allergy seems safe and effective in patients with mastocytosis.
CONCLUSIONS: VIT is safe in cutaneous mastocytosis patients with WA, while caution has to be made in case of systemic mastocytosis. VIT was effective in the patients who were re-stung. PMID: 26549336 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - November 11, 2015 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Pre-seasonal, subcutaneous immunotherapy: a double-blinded, placebo-controlled study in elderly patients with an allergy to grass.
CONCLUSION: Pre-seasonal SCIT in the elderly is safe and efficacious and elicits an immune response comparable to what is found in studies of younger patients. PMID: 26815709 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - January 28, 2016 Category: Allergy & Immunology Authors: Bozek A, Kolodziejczyk K, Krajewska-Wojtys A, Jarzab J Tags: Ann Allergy Asthma Immunol Source Type: research

Synchronous telehealth for outpatient allergy consultations: A 2-year regional experience.
CONCLUSION: Both new and follow-up visits to the allergist/immunologist were well received by patients and demonstrated significant indirect cost savings, with less than one fourth of the patients recommended for an in-person visit. This appears to be the first systematic assessment of TeleAllergy for new and follow-up patient encounters in a clinic-based allergy/immunology practice. PMID: 27105676 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - April 18, 2016 Category: Allergy & Immunology Authors: Waibel KH Tags: Ann Allergy Asthma Immunol Source Type: research

Unusual allergy to soy appeared in adult age.
Authors: Asero R, Mistrello G, Amato S, Villalta D Abstract A case of adult onset severe soy allergy is discussed. The allergen protein involved did not correspond to those presently detectable by commercial diagnostic means, but was not identified, possibly due to the insufficient level of specific IgE. Fresh foods and commercial food extracts remain an invaluable tool to support the diagnosis of food allergy, both in-vivo and in-vitro. PMID: 27152605 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - May 8, 2016 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Translation to Portuguese and cultural adaptation of Food Allergy Quality of Life Questionnaire - Parent Form (FAQLQ-PF).
Authors: Couto M, Silva D, Piedade S, Borrego L, Flokstra-de Blok B, Dunn Galvin A, Morais-Almeida M Abstract Food allergy is a health problem with significant negative impact in Quality of Life (QoL). We aimed to translate into Portuguese and culturally adapt to our population the Food Allergy Quality of Life Questionnaire - Parent Form (FAQLQ-PF). Cross-cultural translation was performed according to guidelines. Linguistic validation consisted in 3 steps: forward translation, backward translation and comprehensibility testing. A consensual version was obtained and tested in parents of food allergic children by co...
Source: European Annals of Allergy and Clinical Immunology - May 8, 2016 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Allergy in urban elderly population living in Campania region (Southern Italy). A multicenter study.
In conclusion, the prevalence and clinical significance of airway allergic sensitization in the elderly living in Campania region is more significant than expected in latter stages of life. Physicians should not neglect the role of atopy as a risk factor for the onset of allergic respiratory symptoms even in elderly patients. PMID: 27425174 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - July 20, 2016 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research