Decreased FOXP3 mRNA expression in children with atopic asthma and IgE-mediated food allergy.

CONCLUSION: Significantly lower levels of FOXP3 gene expression, observed more commonly in children with asthma and IgE-dependent FA than in healthy controls, were associated with a more severe clinical course. Therefore, FOXP3 expression could serve as an indicator of severe asthma with concomitant atopic conditions such as IgE-dependent FA. PMID: 26409874 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26409874?dopt=Abstract

Source: Annals of Allergy, Asthma and Immunology - September 22, 2015 Category: Allergy & Immunology Authors: Krogulska A, Polakowska E, Wąsowska-Królikowska K, Małachowska B, Młynarski W, Borowiec M Tags: Ann Allergy Asthma Immunol Source Type: research