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Condition: Autoimmune Disease
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Total 2213 results found since Jan 2013.
Ginger Consumption May Mitigate Neutrophil Dysfunction Ginger Consumption May Mitigate Neutrophil Dysfunction
An oral ginger extract was associated with reduced action of the neutrophil activity associated with the development of autoimmune and inflammatory diseases.Medscape Medical News
Source: Medscape Allergy Headlines - September 22, 2023 Category: Allergy & Immunology Tags: Rheumatology News Source Type: news
European Commission Approves First Tocilizumab Biosimilar European Commission Approves First Tocilizumab Biosimilar
The biosimilar, commercially called Tyenne, is indicated to treat several autoimmune diseases as well as cytokine release syndrome and COVID-19.Medscape Medical News
Source: Medscape Allergy Headlines - September 21, 2023 Category: Allergy & Immunology Tags: Rheumatology News Source Type: news
Acquired angioedema due to C1-inhibitor-deficiency (AAE-C1-INH) - a bi-center retrospective study on diagnosis, course and therapy
CONCLUSION: AAE-C1-INH is characterized by late onset swellings mainly involving the face and low C1-INH levels. Diagnostic delay for AAE-C1-INH is further decreasing despite being about 10-fold rarer than HAE. Patients severely affected without underlying condition or no indication for treatment could benefit from off-label therapy.PMID:37716525 | DOI:10.1016/j.jaip.2023.09.003
Source: Cancer Control - September 16, 2023 Category: Cancer & Oncology Authors: Felix Johnson Janina Hahn Benedikt Hofauer Jens Greve Barbara Wollenberg Thomas K Hoffmann Robin Lochbaum Susanne Trainotti Source Type: research
The Influence of Sex Hormones and X Chromosome in Immune Responses
Curr Top Microbiol Immunol. 2023;441:21-59. doi: 10.1007/978-3-031-35139-6_2.ABSTRACTMales and females differ in their susceptibility to develop autoimmunity and allergy but also in their capacity to cope with infections and cancers. Cellular targets and molecular pathways underlying sexual dimorphism in immunity have started to emerge and appeared multifactorial. It became increasingly clear that sex-linked biological factors have important impact on the development, tissue maintenance and effector function acquisition of distinct immune cell populations, thereby regulating multiple layers of innate or adaptive immunity t...
Source: Current Topics in Microbiology and Immunology - September 11, 2023 Category: Microbiology Authors: Nina Anesi Charles-Henry Miquel Sophie Laffont Jean-Charles Gu éry Source Type: research
Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis
CONCLUSION Autoreactive, proinflammatory CD4+ T cells and autoantibodies develop to ECM proteins in a subgroup of postinfectious LA patients who have specific HLA-DR alleles. Rather than the traditional molecular mimicry model, we propose that epitope spreading provides the best explanation for this example of infection-induced autoimmunity.FUNDING Supported by National Institute of Allergy and Infectious Diseases R01-AI101175, R01-AI144365, and F32-AI125764; National Institute of Arthritis and Musculoskeletal and Skin Diseases K01-AR062098 and T32-AR007258; NIH grants P41-GM104603, R24-GM134210, S10-RR020946, S10-OD010724...
Source: Journal of Clinical Investigation - September 1, 2023 Category: Biomedical Science Authors: Korawit Kanjana, Klemen Strle, Robert B. Lochhead, Annalisa Pianta, Laura M. Mateyka, Qi Wang, Sheila L. Arvikar, David E. Kling, Cameron A. Deangelo, Lucy Curham, Alan G. Barbour, Catherine E. Costello, James J. Moon, Allen C. Steere Source Type: research
An updated review of pandas/pans disease also known as idiopathic autoimmune encephalitis: what the allergist should know
CONCLUSION: Due to the complexity and variability in how patients with IAE may present to the Allergist/Immunologist office, an interdisciplinary approach is imperative to provide patients with the best medical care. Still, additional research is needed to further elucidate the mechanism(s) and optimal treatment algorithm for IAE in order to facilitate broader recognition and acceptance of this condition by the medical community.PMID:37634580 | DOI:10.1016/j.anai.2023.08.022
Source: Annals of Allergy, Asthma and Immunology - August 27, 2023 Category: Allergy & Immunology Authors: Hannah Hardin Wenhai Shao Jonathan A Bernstein Source Type: research
An updated review of pandas/pans disease also known as idiopathic autoimmune encephalitis: what the allergist should know
CONCLUSION: Due to the complexity and variability in how patients with IAE may present to the Allergist/Immunologist office, an interdisciplinary approach is imperative to provide patients with the best medical care. Still, additional research is needed to further elucidate the mechanism(s) and optimal treatment algorithm for IAE in order to facilitate broader recognition and acceptance of this condition by the medical community.PMID:37634580 | DOI:10.1016/j.anai.2023.08.022
Source: Annals of Allergy, Asthma and Immunology - August 27, 2023 Category: Allergy & Immunology Authors: Hannah Hardin Wenhai Shao Jonathan A Bernstein Source Type: research
An updated review of pandas/pans disease also known as idiopathic autoimmune encephalitis: what the allergist should know
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), further subcategorized as Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus (PANDAS), is a form of Idiopathic Autoimmune Encephalitis (IAE). Post-streptococcal autoimmunity seen in IAE manifests as various neuropsychiatric symptoms such as obsessive rituals, tics, anxiety, depression, and many others. IAE has clinically heterogeneous phenotypes that make accurate diagnosing difficult, though diagnostic testing such as the Cunningham Panel increases the likelihood of finding effective treatments.
Source: Annals of Allergy, Asthma and Immunology - August 25, 2023 Category: Allergy & Immunology Authors: Hannah Hardin, Wenhai Shao, Jonathan A. Bernstein Tags: Review Source Type: research
