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Condition: Autoimmune Disease

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Total 2213 results found since Jan 2013.

Trimethoprim-sulfamethoxazole-induced aseptic meningitis-not just another sulfa allergy.
CONCLUSION: TMP-SMX is the most common antibiotic to cause drug-induced aseptic meningitis. By being aware of this reaction, allergists are well poised to diagnose TSIAM and prevent future reoccurrences for the patient. PMID: 25240332 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - September 17, 2014 Category: Allergy & Immunology Authors: Bruner KE, Coop CA, White KM Tags: Ann Allergy Asthma Immunol Source Type: research

Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
CONCLUSION: In conclusion, chitinases can be used as potential biomarkers in prognosis and diagnosis of several inflammatory diseases and allergies and the design of novel chitinase inhibitors may act as key and rational scaffolds in designing of some novel therapeutic agents in the treatment of variety of inflammatory diseases. PMID: 31934842 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - January 15, 2020 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

Pediatric allergy and immunology in Israel
Abstract After the geographic and sociodemographic settings as well as the health care in Israel are briefly described, the scope of pediatric allergy and immunology in Israel is presented. This includes specific disorders commonly encountered, the environment that induces symptoms, the specialists who treat them, and the common challenges of patients, parents, doctors, and allied health personnel who collaborate to manage the maladies and patient care. Allergies usually affect some overall 15–20% of the pediatric population. The main allergens are inhaled, ingested, or injected (insects stings). Generally, the incidence...
Source: Pediatric Allergy and Immunology - February 3, 2013 Category: Allergy & Immunology Authors: Carmi Geller‐Bernstein, Amos Etzioni Tags: Original Article Source Type: research

An In-Depth Characterization of a Large Cohort of Adults Patients with Eosinophilic Esophagitis.
CONCLUSION: Our adult cohort of manually verified, biopsy-proven EoE showed increased risk of pollen food allergy syndrome, anaphylaxis, and comorbid autoimmune and psychiatric conditions compared with the UPHS population. There was also an increased prevalence of impaction and stricture/fibrosis requiring endoscopic intervention compared with the pediatric population. PMID: 30223114 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - September 14, 2018 Category: Allergy & Immunology Authors: Leigh LY, Spergel JM Tags: Ann Allergy Asthma Immunol Source Type: research

Physicians' experience and opinion on contraindications to allergen immunotherapy: The CONSIT survey.
CONCLUSION: Major problems were infrequent and experienced physicians were less likely to be restrictive in the use of AIT. PMID: 28477792 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - May 1, 2017 Category: Allergy & Immunology Authors: Rodríguez Del Rio P, Pitsios C, Tsoumani M, Pfaar O, Paraskevopoulos G, Gawlik R, Valovirta E, Larenas-Linnemann D, Demoly P, Calderón MA Tags: Ann Allergy Asthma Immunol Source Type: research

Identifying True Celiac Disease and Wheat Allergy in the Era of Fashion Driven Gluten-Free Diets
Conclusions: tTGIgA were increasingly tested, while the rate of positive results decreased in recent years, possibly reflecting the impact of current alimentary trends on clinical practice. Associated autoimmune disease was frequently found in CD. High levels of tTGIgA accurately predicted CD diagnosis. WA was rarely investigated and deserves more attention, in particular in children with atopic background. WA does not seem to be associated with CD.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - March 21, 2019 Category: Allergy & Immunology Source Type: research

Neutrophil-like low-density granulocytes are elevated in patients with moderate to severe persistent asthma.
CONCLUSION: These findings identify a previously unrecognized association between LDG levels and asthma severity. Identification of the factor(s) responsible for the increased LDG levels in moderate persistent or SP asthma may provide a serum biomarker to aid in the identification of neutrophil-associated phenotypes of severe asthma. PMID: 25256681 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - September 23, 2014 Category: Allergy & Immunology Authors: Fu J, Tobin MC, Thomas LL Tags: Ann Allergy Asthma Immunol Source Type: research

Worms as therapeutic agents for allergy and asthma: Understanding why benefits in animal studies have not translated into clinical success
Helminth infections are associated with decreased rates of autoimmunity and allergy, and several clinical studies have demonstrated that intentional infection with helminths can reduce symptoms of autoimmune diseases. In contrast, though numerous animal studies have demonstrated that helminth infections ameliorate allergic diseases, clinical trials in humans have not shown benefit. In this article, we review in detail the 2 human studies that have prospectively tested whether helminth infections protect against allergy.
Source: Journal of Allergy and Clinical Immunology - August 28, 2014 Category: Allergy & Immunology Authors: Holly Evans, Edward Mitre Source Type: research

Food allergy in patients with primary immunodeficiency diseases: Prevalence within the US Immunodeficiency Network (USIDNET)
Primary immunodeficiency diseases (PIDDs) are congenital disorders caused by inherent defects in the immune system that typically present with recurrent or severe infections but can also involve autoimmune disease, lymphoproliferation, or allergy.1 Allergic diseases are an important expression of misdirected immunity, and certain PIDDs are frequently associated with atopy. Selective IgA deficiency (SIgAD) has been associated with asthma, allergic rhinitis, atopic dermatitis (AD), and food allergy (FA).
Source: Journal of Allergy and Clinical Immunology - November 25, 2014 Category: Allergy & Immunology Authors: Karen S. Tuano, Jordan S. Orange, Kathleen Sullivan, Charlotte Cunningham-Rundles, Francisco A. Bonilla, Carla M. Davis Tags: Letter to the Editor Source Type: research

Shared genetic variants suggest common pathways in allergy and autoimmune diseases
We identified shared susceptibility loci and commonalities in pathways between allergy and autoimmune diseases. Further studies of these loci and related mechanisms might help understanding the complex relationship between allergy and autoimmunity.
Source: Journal of Allergy and Clinical Immunology - February 7, 2017 Category: Allergy & Immunology Authors: Eskil Kreiner, Johannes Waage, Marie Standl, Susanne Brix, Tune H. Pers, Alexessander Couto Alves, Nicole M. Warrington, Carla MT. Tiesler, Elaine Fuertes, Lude Franke, Joel N. Hirschhorn, Alan James, Angela Simpson, Joyce Y. Tung, Gerard H. Koppelman, Di Source Type: research

Advances in cutaneous allergy
Atopic dermatitis (AD) has now been well documented to be associated with an important impact on quality of life and is a major driver of not only systemic comorbidities including other allergic diseases (such as asthma and food allergy) but also cardiovascular and autoimmune diseases.1 Sleep disturbance and adverse effects on mental health are common in patients with AD. A major contributor for these events is the skin and resultant systemic immune activation associated with AD.2 Recent studies support the importance of skin barrier dysfunction in driving cutaneous allergy.
Source: Annals of Allergy, Asthma and Immunology - December 6, 2020 Category: Allergy & Immunology Authors: Donald Y.M. Leung Tags: Editorial Source Type: research

Systemic lupus erythematosus is associated with increased risk for radiocontrast allergy
Systemic lupus erythematosus (SLE) is a chronic autoimmune condition that can manifest in multiple organs. Imaging is common to confirm systemic involvement of disease and may frequently require the use of radioactive contrast. Hypersensitivity reaction to radioactive contrast media and dye is rare but moderate to severe reactions can complicate a patient's clinical course. Immunologic dysregulation plays a significant role in both SLE and radiocontrast allergy. We investigate the association between contrast allergy and SLE in this study using a large nationwide database.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: N. Rawal, S. Imam, A. Shaikh, E. Capitle Tags: P020 Source Type: research

Autoantibodies in chronic idiopathic urticaria and nonurticarial systemic autoimmune disorders.
CONCLUSION: The CU Index values were elevated in patients with CU and SLE. The presence of these autoantibodies did not correlate with disease activity or presence of thyroid antibodies. Functional autoantibodies may not be specific for chronic idiopathic urticaria, and their role in nonurticarial systemic autoimmune diseases requires further investigation. PMID: 23244655 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - January 1, 2013 Category: Allergy & Immunology Authors: Cho CB, Stutes SA, Altrich ML, Ardoin SP, Phillips G, Ogbogu PU Tags: Ann Allergy Asthma Immunol Source Type: research

Intravenous Immunoglobulın Therapy in Dermatology: An Update.
Abstract Intravenous immunoglobulin (IVIG) is a fractioned blood product consisting of IgG antibodies which was first used in antibody deficiency disorders. It is increasingly being used for several inflammatory and autoimmune conditions. IVIG can also be used in a wide range of dermatological diseases which are difficult to treat including autoimmune bullous skin diseases and toxic epidermal necrolysis. The use of IVIG in dermatological disorders is discussed in this article. PMID: 23360252 [PubMed - as supplied by publisher]
Source: Inflammation and Allergy Drug Targets - January 22, 2013 Category: Allergy & Immunology Authors: Cakmak SK, Cakmak A, Gönül M, Kılıç A, Gül U Tags: Inflamm Allergy Drug Targets Source Type: research