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Condition: Autoimmune Disease
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Total 2213 results found since Jan 2013.
Immune Responses at Host Barriers and Their Importance in Systemic Autoimmune Diseases
Adv Exp Med Biol. 2023;1408:3-24. doi: 10.1007/978-3-031-26163-3_1.ABSTRACTHost barriers such as the skin, the lung mucosa, the intestinal mucosa and the oral cavity are crucial at preventing contact with potential threats and are populated by a diverse population of innate and adaptive immune cells. Alterations in antigen recognition driven by genetic and environmental factors can lead to autoimmune systemic diseases such rheumatoid arthritis, systemic lupus erythematosus and food allergy. Here we review how different immune cells residing at epithelial barriers, host-derived signals and environmental signals are involved...
Source: Advances in Experimental Medicine and Biology - April 24, 2023 Category: Research Authors: Katina Schinnerling Hugo A Penny Jorge A Soto Felipe Melo-Gonzalez Source Type: research
A rare immunological disease, caspase 8 deficiency: case report and literature review
Caspase-8 is a molecule in the FAS pathway that initiates apoptosis. One of the rarest autoimmune lymphoproliferative syndromes is caspase-8 deficiency. Immunodeficiency, splenomegaly, and lymphadenopathy are ...
Source: Allergy, Asthma and Clinical Immunology - April 10, 2023 Category: Allergy & Immunology Authors: Narges Bazgir, Azin Tahvildari, Zahra Chavoshzade, Mahnaz Jamee, Zahra Golchehre, Abdollah Karimi, Naghi Dara, Mazdak Fallahi, Mohammad Keramatipour, Arezou Karamzade and Samin Sharafian Tags: Case report Source Type: research
Nanoparticle with mRNA appears to prevent, treat peanut allergies in mice
Key takeawaysPeanuts are one of the most common food allergens for children.UCLA scientists have developed a nanoparticle that delivers mRNA to liver cells in order to teach the immune system to tolerate peanut protein and alleviate allergies.In mice, the nanoparticle successfully dampened symptoms of serious allergy.Peanut allergies affect 1 in 50 children, and the most severe cases lead to a potentially deadly immune reaction called anaphylactic shock.Currently, there is only one approved treatment that reduces the severity of the allergic reaction, and it takes months to kick in. A group of UCLA immunologists is aiming ...
Source: UCLA Newsroom: Health Sciences - April 3, 2023 Category: Universities & Medical Training Source Type: news
