Correction to: The Data Behind Risk Analysis of Campylobacter Jejuni and Campylobacter Coli Infections
Curr Top Microbiol Immunol. 2021;431:C1. doi: 10.1007/978-3-030-65481-8_12.NO ABSTRACTPMID:33886025 | DOI:10.1007/978-3-030-65481-8_12 (Source: Current Topics in Microbiology and Immunology)
Source: Current Topics in Microbiology and Immunology - April 22, 2021 Category: Microbiology Authors: Racem Ben Romdhane Roswitha Merle Source Type: research

Epidemiology of Lassa Fever
Curr Top Microbiol Immunol. 2021 Apr 17. doi: 10.1007/82_2021_234. Online ahead of print.ABSTRACTLassa fever (LF) is a lethal hemorrhagic disease primarily concentrated in the tropical savannah regions of Nigeria and the Mano River Union countries of Sierra Leone, Liberia, and Guinea. Endemic hotspots within these countries have had recurrent exposure to Lassa virus (LASV) via continual spillover from the host reservoir Mastomys natalensis. Increased trade and travel throughout the region have spread the virus to previously unexposed countries, including Ghana, Benin, Mali, and Côte d'Ivoire. In the absence of effect...
Source: Current Topics in Microbiology and Immunology - April 16, 2021 Category: Microbiology Authors: Antoinette R Bell-Kareem Allison R Smither Source Type: research

Self-amplifying mRNA-Based Vaccine Technology and Its Mode of Action
Curr Top Microbiol Immunol. 2021 Apr 17. doi: 10.1007/82_2021_233. Online ahead of print.ABSTRACTSelf-amplifying mRNAs derived from the genomes of positive-strand RNA viruses have recently come into focus as a promising technology platform for vaccine development. Non-virally delivered self-amplifying mRNA vaccines have the potential to be highly versatile, potent, streamlined, scalable, and inexpensive. By amplifying their genome and the antigen encoding mRNA in the host cell, the self-amplifying mRNA mimics a viral infection, resulting in sustained levels of the target protein combined with self-adjuvanting innate immune...
Source: Current Topics in Microbiology and Immunology - April 16, 2021 Category: Microbiology Authors: Giulietta Maruggi Jeffrey B Ulmer Rino Rappuoli Dong Yu Source Type: research

Epidemiology of Lassa Fever
Curr Top Microbiol Immunol. 2021 Apr 17. doi: 10.1007/82_2021_234. Online ahead of print.ABSTRACTLassa fever (LF) is a lethal hemorrhagic disease primarily concentrated in the tropical savannah regions of Nigeria and the Mano River Union countries of Sierra Leone, Liberia, and Guinea. Endemic hotspots within these countries have had recurrent exposure to Lassa virus (LASV) via continual spillover from the host reservoir Mastomys natalensis. Increased trade and travel throughout the region have spread the virus to previously unexposed countries, including Ghana, Benin, Mali, and Côte d'Ivoire. In the absence of effect...
Source: Current Topics in Microbiology and Immunology - April 16, 2021 Category: Microbiology Authors: Antoinette R Bell-Kareem Allison R Smither Source Type: research

Self-amplifying mRNA-Based Vaccine Technology and Its Mode of Action
Curr Top Microbiol Immunol. 2021 Apr 17. doi: 10.1007/82_2021_233. Online ahead of print.ABSTRACTSelf-amplifying mRNAs derived from the genomes of positive-strand RNA viruses have recently come into focus as a promising technology platform for vaccine development. Non-virally delivered self-amplifying mRNA vaccines have the potential to be highly versatile, potent, streamlined, scalable, and inexpensive. By amplifying their genome and the antigen encoding mRNA in the host cell, the self-amplifying mRNA mimics a viral infection, resulting in sustained levels of the target protein combined with self-adjuvanting innate immune...
Source: Current Topics in Microbiology and Immunology - April 16, 2021 Category: Microbiology Authors: Giulietta Maruggi Jeffrey B Ulmer Rino Rappuoli Dong Yu Source Type: research

Epidemiology of Lassa Fever
Curr Top Microbiol Immunol. 2021 Apr 17. doi: 10.1007/82_2021_234. Online ahead of print.ABSTRACTLassa fever (LF) is a lethal hemorrhagic disease primarily concentrated in the tropical savannah regions of Nigeria and the Mano River Union countries of Sierra Leone, Liberia, and Guinea. Endemic hotspots within these countries have had recurrent exposure to Lassa virus (LASV) via continual spillover from the host reservoir Mastomys natalensis. Increased trade and travel throughout the region have spread the virus to previously unexposed countries, including Ghana, Benin, Mali, and Côte d'Ivoire. In the absence of effect...
Source: Current Topics in Microbiology and Immunology - April 16, 2021 Category: Microbiology Authors: Antoinette R Bell-Kareem Allison R Smither Source Type: research

Self-amplifying mRNA-Based Vaccine Technology and Its Mode of Action
Curr Top Microbiol Immunol. 2021 Apr 17. doi: 10.1007/82_2021_233. Online ahead of print.ABSTRACTSelf-amplifying mRNAs derived from the genomes of positive-strand RNA viruses have recently come into focus as a promising technology platform for vaccine development. Non-virally delivered self-amplifying mRNA vaccines have the potential to be highly versatile, potent, streamlined, scalable, and inexpensive. By amplifying their genome and the antigen encoding mRNA in the host cell, the self-amplifying mRNA mimics a viral infection, resulting in sustained levels of the target protein combined with self-adjuvanting innate immune...
Source: Current Topics in Microbiology and Immunology - April 16, 2021 Category: Microbiology Authors: Giulietta Maruggi Jeffrey B Ulmer Rino Rappuoli Dong Yu Source Type: research

Epidemiology of Lassa Fever
Curr Top Microbiol Immunol. 2021 Apr 17. doi: 10.1007/82_2021_234. Online ahead of print.ABSTRACTLassa fever (LF) is a lethal hemorrhagic disease primarily concentrated in the tropical savannah regions of Nigeria and the Mano River Union countries of Sierra Leone, Liberia, and Guinea. Endemic hotspots within these countries have had recurrent exposure to Lassa virus (LASV) via continual spillover from the host reservoir Mastomys natalensis. Increased trade and travel throughout the region have spread the virus to previously unexposed countries, including Ghana, Benin, Mali, and Côte d'Ivoire. In the absence of effect...
Source: Current Topics in Microbiology and Immunology - April 16, 2021 Category: Microbiology Authors: Antoinette R Bell-Kareem Allison R Smither Source Type: research

Self-amplifying mRNA-Based Vaccine Technology and Its Mode of Action
Curr Top Microbiol Immunol. 2021 Apr 17. doi: 10.1007/82_2021_233. Online ahead of print.ABSTRACTSelf-amplifying mRNAs derived from the genomes of positive-strand RNA viruses have recently come into focus as a promising technology platform for vaccine development. Non-virally delivered self-amplifying mRNA vaccines have the potential to be highly versatile, potent, streamlined, scalable, and inexpensive. By amplifying their genome and the antigen encoding mRNA in the host cell, the self-amplifying mRNA mimics a viral infection, resulting in sustained levels of the target protein combined with self-adjuvanting innate immune...
Source: Current Topics in Microbiology and Immunology - April 16, 2021 Category: Microbiology Authors: Giulietta Maruggi Jeffrey B Ulmer Rino Rappuoli Dong Yu Source Type: research

Epidemiology of Lassa Fever
Curr Top Microbiol Immunol. 2021 Apr 17. doi: 10.1007/82_2021_234. Online ahead of print.ABSTRACTLassa fever (LF) is a lethal hemorrhagic disease primarily concentrated in the tropical savannah regions of Nigeria and the Mano River Union countries of Sierra Leone, Liberia, and Guinea. Endemic hotspots within these countries have had recurrent exposure to Lassa virus (LASV) via continual spillover from the host reservoir Mastomys natalensis. Increased trade and travel throughout the region have spread the virus to previously unexposed countries, including Ghana, Benin, Mali, and Côte d'Ivoire. In the absence of effect...
Source: Current Topics in Microbiology and Immunology - April 16, 2021 Category: Microbiology Authors: Antoinette R Bell-Kareem Allison R Smither Source Type: research

Self-amplifying mRNA-Based Vaccine Technology and Its Mode of Action
Curr Top Microbiol Immunol. 2021 Apr 17. doi: 10.1007/82_2021_233. Online ahead of print.ABSTRACTSelf-amplifying mRNAs derived from the genomes of positive-strand RNA viruses have recently come into focus as a promising technology platform for vaccine development. Non-virally delivered self-amplifying mRNA vaccines have the potential to be highly versatile, potent, streamlined, scalable, and inexpensive. By amplifying their genome and the antigen encoding mRNA in the host cell, the self-amplifying mRNA mimics a viral infection, resulting in sustained levels of the target protein combined with self-adjuvanting innate immune...
Source: Current Topics in Microbiology and Immunology - April 16, 2021 Category: Microbiology Authors: Giulietta Maruggi Jeffrey B Ulmer Rino Rappuoli Dong Yu Source Type: research

Virus-Like Particle Vaccines Against Respiratory Viruses and Protozoan Parasites
Curr Top Microbiol Immunol. 2021 Mar 3. doi: 10.1007/82_2021_232. Online ahead of print.ABSTRACTThe field of vaccinology underwent massive advances over the past decades with the introduction of virus-like particles (VLPs), a supra-molecular nanoparticle vaccine platform that resembles viral structures without the ability to replicate in hosts. This innovative approach has been remarkably effective, as evidenced by its profound immunogenicity and safety. These highly desirable intrinsic properties enabled their further development as vaccines against a multitude of diseases. To date, several VLP-based vaccines have already...
Source: Current Topics in Microbiology and Immunology - March 2, 2021 Category: Microbiology Authors: Ki-Back Chu Fu-Shi Quan Source Type: research