Filtered By:
Nutrition: Antidoxidants
This page shows you your search results in order of date.
Order by Relevance | Date
Total 54788 results found since Jan 2013.
In silico Analysis of SOD1 Aggregation Inhibition Modes of Tertiary Amine Pyrazolone and Pyrano Coumarin Ferulate as ALS drug candidates
Phys. Chem. Chem. Phys., 2023, Accepted Manuscript DOI: 10.1039/D3CP03978A, PaperAziza Rahman, Bondeepa Saikia, Anupaul Baruah Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, the familial form (fALS) of which is often cognated to mutations in the antioxidant enzyme Cu/Zn superoxide dismutase 1 (SOD1) leading... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - September 23, 2023 Category: Chemistry Authors: Aziza Rahman Source Type: research
Oxidized galectin-1 in SLE fails to bind the inhibitory receptor VSTM1 and increases reactive oxygen species levels in neutrophils
Cell Mol Immunol. 2023 Sep 22. doi: 10.1038/s41423-023-01084-z. Online ahead of print.ABSTRACTInhibitory immune receptors set thresholds for immune cell activation, and their deficiency predisposes a person to autoimmune responses. However, the agonists of inhibitory immune receptors remain largely unknown, representing untapped sources of treatments for autoimmune diseases. Here, we show that V-set and transmembrane domain-containing 1 (VSTM1) is an inhibitory receptor and that its binding by the competent ligand soluble galectin-1 (Gal1) is essential for maintaining neutrophil viability mediated by downregulated reactive...
Source: Cellular and Molecular Immunology - September 22, 2023 Category: Molecular Biology Authors: Xu Jiang Xinyue Xiao Hao Li Yiyi Gong Min Wang Huaxia Yang Lidan Zhao Ying Jiang Yanping Wei Chongchong Zhao Jin Li Yuling Chen Shan Feng Haiteng Deng Shiliang Ma Yue Xu Yudong Liu George C Tsokos Minghong Jiang Xuan Zhang Source Type: research
Effects of < em > Aeriscardovia aeriphila < /em > on growth performance, antioxidant functions, immune responses, and gut microbiota in broiler chickens
In conclusion, oral administration of A. aeriphila could improve the growth performance, serum antioxidant capacity, immune modulation, and gut health of broilers. Our findings may provide important information for the application of A. aeriphila in poultry production.PMID:37735944 | DOI:10.1631/jzus.B2200621
Source: J Zhejiang Univ Sci ... - September 22, 2023 Category: Science Authors: Muhammad Zahid Farooq Xinkai Wang Xianghua Yan Source Type: research
Comparison of Effectiveness of Moringa Oleifera Leaves Extract Gel (2%) with Retino A (0.1%) Cream for Treatment of Oral Leukoplakia: Double Blinded Randomized Control Trial
CONCLUSION: This study showed that M. oleifera mucoadhesive gel (2%) is an effective and safe treatment option for oral leukoplakia patients. It demonstrated a significant reduction in lesion size compared to Retino-A cream (0.1%) after 3 months of therapy, without any reported adverse effects. However, long-term follow-up studies are needed to evaluate its long-term effectiveness. The potent antioxidant property of M. oleifera makes it a promising candidate for further studies with concentration variations and in other potentially malignant oral disorders, such as lichen planus and OSMF. The development of chemotherapeuti...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Sulem Ansari Shivayogi Charantimath Anabelle Fernandes Jayraj B Malik Prashanth Panta Source Type: research
Toxicity of bisphenol A (BPA) and its analogues BPF and BPS on the free-floating macrophyte Salvinia biloba
Chemosphere. 2023 Sep 19:140235. doi: 10.1016/j.chemosphere.2023.140235. Online ahead of print.ABSTRACTEvidence linking the toxicity of bisphenol A (BPA) to environmental and public-health issues has led to restrictions on its use. This compound has been gradually replaced with analogues proposed as a safer alternative, normally bisphenol F (BPF) and bisphenol S (BPS), but these substitutes are structurally almost identical to BPA, suggesting they may pose similar risks. The effects of BPA and these analogues were compared for antioxidant activity, lipid peroxidation, free-radical generation, photosynthetic pigments, and c...
Source: Chemosphere - September 21, 2023 Category: Chemistry Authors: Jaqueline da Silva Santos Montcharles da Silva Pontes Matheus Bispo de Souza Simone Yasuda Fernandes Ricardo Antunes de Azevedo Gilberto Jos é de Arruda Etenaldo Felipe Santiago Source Type: research
Catechin hydrate ameliorates cerulein ‑induced chronic pancreatitis via the inactivation of TGF‑β/Smad2 signaling
Mol Med Rep. 2023 Nov;28(5):208. doi: 10.3892/mmr.2023.13095. Epub 2023 Sep 21.ABSTRACTChronic pancreatitis (CP) is a pancreatic inflammatory disease associated with histological changes, including fibrosis, acinar cell loss and immune cell infiltration, and leads to damage of the pancreas, which results in pain, weight loss and loss of pancreas function. Catechin or catechin hydrate (CH) has antioxidant, anticancer and immune‑regulatory effects. However, unlike other catechins, the antifibrotic effects of (+)‑CH have not been widely studied in many diseases, including CP. Therefore, the anti‑fibrotic effects of (+)â...
Source: Molecular Medicine - September 21, 2023 Category: Molecular Biology Authors: Bitna Kweon Dong-Uk Kim Jin-Young Oh Sung-Joo Park Gi-Sang Bae Source Type: research
Exploring the antioxidant, antimicrobial, cytotoxic and biothermodynamic properties of novel morpholine derivative bioactive Mn(ii), Co(ii) and Ni(ii) complexes - combined experimental and theoretical measurements towards DNA/BSA/SARS-CoV-2 3CL < sup > Pro < /sup >
RSC Med Chem. 2023 Jan 3;14(9):1667-1697. doi: 10.1039/d2md00394e. eCollection 2023 Sep 19.ABSTRACTA novel class of bioactive complexes (1-3) [MII(L)2(bpy)], where, L = 2-(4-morpholinobenzylideneamino)phenol, bpy = 2,2'-bipyridine, MII = Mn (1), Co (2) or Ni (3), were assigned to octahedral geometry based on analytical and spectral measurements. Gel electrophoresis showed that complex (2) demonstrated significant DNA cleavage activity compared to the other complexes under the action of oxidation agent (H2O2). The DNA binding constant properties measured by various techniques were in the following sequence: (2) > (3) >...
Source: Molecular Medicine - September 21, 2023 Category: Molecular Biology Authors: Karunganathan Sakthikumar Bienfait Kabuyaya Isamura Rui Werner Ma çedo Krause Source Type: research
Effects of Dietary Valine Chelated Zinc Supplementation on Growth Performance, Antioxidant Capacity, Immunity, and Intestine Health in Weaned Piglets
In conclusion, the present research showed that supplementation of ZnVal improves growth performance by increasing antioxidant capacity and immunity and regulating intestinal morphology and the optimal inclusion level of ZnVal was 65~80 mg/kg.PMID:37730969 | DOI:10.1007/s12011-023-03870-2
Source: Biological Trace Element Research - September 21, 2023 Category: Biology Authors: Tuan Zhang Nan Zhang Shuyu Peng Yawei Zhang Huakai Wang Shiyu Huang Min Zhu Yongxi Ma Source Type: research
The performance of hypochlorous acid modified Ag nanoparticle-based assay in the determination of total antioxidant capacity of Boswellia Serrata and Aronia
In this study, the SNPAC method was developed by using hypochlorous (ClO-) at pH 9.3. Polyvinylpyrrolidone (PVP) was used as a stabilizer. The existence of HOCl enables to formation stronger and more stable yellow emission which gives sensitivity. As a result, lower LOD and LOQ values were achieved by the AgNP-HOCl method. The obtaining lower values was attributed to the reoxidation of silver atoms with ClO- ions in the presence of PVP. The newly modified method was applied to the total antioxidant capacity (TAC) measurement of Boswellia Serrata, Aronia Melanocarpa tea, and juice. The results were compared with the results...
Source: Talanta - September 21, 2023 Category: Chemistry Authors: Z ülal Eryaman Julide Hizal Mesut Y ılmazoğlu U ğur Daban Hande Mert Nergiz Kanmaz Source Type: research
Toxicity of bisphenol A (BPA) and its analogues BPF and BPS on the free-floating macrophyte Salvinia biloba
Chemosphere. 2023 Sep 19:140235. doi: 10.1016/j.chemosphere.2023.140235. Online ahead of print.ABSTRACTEvidence linking the toxicity of bisphenol A (BPA) to environmental and public-health issues has led to restrictions on its use. This compound has been gradually replaced with analogues proposed as a safer alternative, normally bisphenol F (BPF) and bisphenol S (BPS), but these substitutes are structurally almost identical to BPA, suggesting they may pose similar risks. The effects of BPA and these analogues were compared for antioxidant activity, lipid peroxidation, free-radical generation, photosynthetic pigments, and c...
Source: Chemosphere - September 21, 2023 Category: Chemistry Authors: Jaqueline da Silva Santos Montcharles da Silva Pontes Matheus Bispo de Souza Simone Yasuda Fernandes Ricardo Antunes de Azevedo Gilberto Jos é de Arruda Etenaldo Felipe Santiago Source Type: research
Multifunctional Polymer Vesicles for Synergistic Antibiotic-Antioxidant Treatment of Bacterial Keratitis
Biomacromolecules. 2023 Sep 21. doi: 10.1021/acs.biomac.3c00754. Online ahead of print.ABSTRACTAs an acute ophthalmic infection, bacterial keratitis (BK) can lead to severe visual morbidity, such as corneal perforation, intraocular infection, and permanent corneal opacity, if rapid and effective treatments are not available. In addition to eradicating pathogenic bacteria, protecting corneal tissue from oxidative damage and promoting wound healing by relieving inflammation are equally critical for the efficient treatment of BK. Besides, it is very necessary to improve the bioavailability of drugs by enhancing the ocular sur...
Source: Biomacromolecules - September 21, 2023 Category: Biochemistry Authors: Qiumeng Chen Xiaopeng Han Lu Liu Yong Duan Yifei Chen Linqi Shi Quankui Lin Liangliang Shen Source Type: research
Phenyl glycosides from < em > Bacopa monnieri < /em > with their antioxidant and anti-inflammatory activities
This study described the isolation and identification of one new, bacomoside D3 (1), and seven known phenyl glycosides (2 - 8). The structures of isolates were established by analysis of their spectroscopic data or hydrolysis followed by HPLC analysis together with a comparison to those reported in the literature. These compounds were evaluated for antioxidant and anti-inflammatory activities. Among them, compounds 4 and 5 exhibited strong DPPH radical scavenging activity with IC50 values of 9.77 ± 0.08 and 3.50 ± 0.04 µM, respectively. Compounds 2 and 5 significantly inhibited TNF-α production in LPS-stimulated RAW264...
Source: Natural Product Research - September 21, 2023 Category: Biochemistry Authors: Thi Phuong Anh Dinh Le Thi Thuy Nguyen Thi Thuy My Van Thong Nguyen Le Huyen Tram Tuan Anh Nguyen Dao Huy Toan Thu Huong Tran Thu Ha Tran Thanh Bui Van Nguyen Van Bach Source Type: research
The protective effect of apigenin against inorganic arsenic salt-induced toxicity in PC12 cells
In conclusion, the obtained results of the present study have clinical significance and indicate that apigenin is a promising candidate for shielding the nervous system from toxic effects caused by arsenic. These findings require further investigation using in vivo experimental models.PMID:37730986 | DOI:10.1007/s11356-023-29884-w
Source: Environmental Science and Pollution Research International - September 21, 2023 Category: Environmental Health Authors: Rafa Almeer Nouf M Alyami Source Type: research
D-pinitol ameliorated H < sub > 2 < /sub > O < sub > 2 < /sub > -induced oxidative damage in PC12 cells and prolonged the lifespan by IIS pathway in Caenorhabditis elegans
In this study, we intended to explore the anti-aging mechanism of DP, utilizing computer modeling techniques. The results demonstrated that DP significantly delayed H2O2-induced cellular senescence. Model PC12 cells treated with DP exhibited increased cell viability, increased antioxidant enzyme activity (SOD, CAT), and reduced ROS and MDA levels. Furthermore, DP was discovered to have a positive effect on healthy longevity. In C. elegans, DP treatment enhanced lifespan, stress capacity, antioxidant capacity (T-SOD/CAT/GSH-Px/MDA/ROS), and altered aging-related indicators of lipofuscin accumulation, pharyngeal pump rate, m...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - September 21, 2023 Category: Biochemistry Authors: Miaosi Zhang Zhe Xu Liangyong Shao Jilite Wang Zouyan He Yumei Jiang Ye Zhang Hao Wang Source Type: research
The protective effect of apigenin against inorganic arsenic salt-induced toxicity in PC12 cells
In conclusion, the obtained results of the present study have clinical significance and indicate that apigenin is a promising candidate for shielding the nervous system from toxic effects caused by arsenic. These findings require further investigation using in vivo experimental models.PMID:37730986 | DOI:10.1007/s11356-023-29884-w
Source: Cell Research - September 21, 2023 Category: Cytology Authors: Rafa Almeer Nouf M Alyami Source Type: research
