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Procedure: Pulmonary Function Testing

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Total 287 results found since Jan 2013.

Effect of vitamin D levels on asthma control in adults
Several studies have shown that low serum levels of Vitamin D are linked to impaired lung function (Cassim, R., et al., Allergy, 2015. 70(4): p. 339-54.). Vitamin D may affect the course of asthma by effects such as anti-inflammatory effect, prevention of respiratory infections and reduction of steroid resistance (Iqbal, et al. J Investig Med, 2011. 59(8): p. 1200-2.). 35 healthy controls and 60 patients with asthma were included in the study between December 2016 and February 2017. Demographic characteristics and pulmonary function tests (PFT) were recorded and laboratory tests were measured. Asthma control test (ACT) was...
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Ciftci, T., Argun Barıs, S., Basyigit, I., Boyacı, H., Ilgazlı, A., Yıldız, F. Tags: Monitoring airway disease Source Type: research

The Relationship between Dietary Inflammatory Index, Pulmonary Functions and Asthma Control in Asthmatics.
In conclusion, an increase in the inflammatory potential of diet among asthmatics decreases pulmonary functions and asthma control. PMID: 32245304 [PubMed - as supplied by publisher]
Source: Iranian Journal of Allergy, Asthma and Immunology - October 29, 2019 Category: Allergy & Immunology Authors: Özbey Ü, Uçar A, Shivappa N, Hebert JR Tags: Iran J Allergy Asthma Immunol Source Type: research

Diamine oxidase enzyme: a novel biomarker in respiratory allergy
ConclusionDAO may be helpful in the assessment of severity and in ruling out respiratory allergy.
Source: International Forum of Allergy and Rhinology - September 17, 2019 Category: Allergy & Immunology Authors: Maged M. Refaat, Asmaa S. Abdel ‐Rehim, Amira R. Elmahdi, Nesrine A. Mohamed, Sara S. Ghonaim Tags: ORIGINAL ARTICLE Source Type: research

Subcutaneous immunotherapy with high-dose cat and dog extracts: a real-life study.
CONCLUSIONS: High-dose SCIT has substantial clinical value in many cat and dog allergic patients. PMID: 31132032 [PubMed - as supplied by publisher]
Source: Journal of Investigational Allergology and Clinical Immunology - May 26, 2019 Category: Allergy & Immunology Authors: Uriarte SA, Sastre J Tags: J Investig Allergol Clin Immunol Source Type: research

Single Inhaler LABA/LAMA for COPD
Conclusions of that meta-analysis should be interpreted with great caution because of differences in population studied, and differences in primary and co-primary outcomes. A recent comparison meta-analysis was not conclusive due to the heterogeneity of phase III studies and the few number of studies for some of the investigated drugs (ACL/FF and GLY/FF in particular), but confirmed that dual bronchodilation was always more effective than LABA or LAMA alone, both in lung function and quality of life indices (Calzetta et al., 2016). This meta-analysis suggested that among the different FDCs may exist a gradient of effectiv...
Source: Frontiers in Pharmacology - April 24, 2019 Category: Drugs & Pharmacology Source Type: research

Markers of Pulmonary Oxygen Toxicity in Hyperbaric Oxygen Therapy Using Exhaled Breath Analysis
Conclusion In this study, after daily HBOT for 6 days, we identified 11 VOCs which could be divided into two PCs. PC1 (inflammation) showed no significant changes over time, PC2 (methyl alkanes) was significantly reduced after daily exposure for 5 days, to approximately 60% after 2 days’ rest. This suggests that daily HBOT does not induce cumulative damage to the pulmonary system of healthy volunteers, but triggers an adaptive response. Additional studies including more treatment sessions, and perhaps additional systemic parameters on radical oxygen scavengers and inflammatory markers, are necessary to substantiate...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

The Human Upper Respiratory Tract Epithelium Is Susceptible to Flaviviruses
In this study, we exposed apically well-differentiated human NECs cultured at the ALI to the related flaviviruses ZIKV, JEV, WNV, and Usutu virus (USUV). We selected these viruses due to the recent increasing evidences of potential threat to humans (Cadar et al., 2017; Simonin et al., 2018). We show that NECs are particularly susceptible to JEV and WNV infection and to other flaviviruses included in this study. Infection with each virus led to shedding of infectious virus particles through the apical and basolateral surfaces and triggered host mechanisms at the level of inflammatory and antiviral mediators....
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research

A Systematic Review on Predisposition to Lymphoid (B and T cell) Neoplasias in Patients With Primary Immunodeficiencies and Immune Dysregulatory Disorders (Inborn Errors of Immunity)
Conclusions Though this is not a comprehensive summary of malignancies in PIDDs, or even lymphoproliferative disease in this area, this review summarizes the Medline-indexed published reports of B and T lymphomas in patients with PIDDs. This report highlights the diversity of malignant lymphoproliferative disorders in setting of PIDDs, and its associated challenges of diagnosis and treatment. The pathological classification and nomenclature for the lymphoid malignancies with variably reported and postulated underlying mechanisms were inconsistent and inadequate for many of these published reports. A wide range of treatmen...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

The Study of Dried Ginger and Linggan Wuwei Jiangxin Decoction Treatment of Cold Asthma Rats Using GC –MS Based Metabolomics
Conclusion In this study, serum and urine metabolites identified by GC–MS and general pharmacodynamic evaluation (morphological observation, histopathology, inflammatory factors, and visceral indices) were used to compare the effects of GJ and LGWWJX decoctions on cold asthma. Significant metabolic abnormalities were observed for 37 metabolites (15 in serum, 22 in urine) in rats with cold asthma. These altered metabolites might be potential biomarkers or therapeutic targets during development of cold asthma. Furthermore, pathway analysis demonstrated that pathways associated with energy metabolism and oxidative str...
Source: Frontiers in Pharmacology - April 10, 2019 Category: Drugs & Pharmacology Source Type: research

A Bidirectional Label Propagation Based Computational Model for Potential Microbe-Disease Association Prediction
Discussion There are numerous microbial communities inhabited in the human body, which is critical to human health. The relationship between human microbiome and diseases received much attention from both medical and bioinformatics community recently. However, traditional methods to detect their association is costly and labor-intensive. Thus, we proposed here a new computational model called NBLPIHMDA to infer potential microbe-disease associations. NBLPIHMDA first combined known microbe-disease associations in HMDAD and the Gaussian interaction profile kernel similarity to construct disease similarity network and microb...
Source: Frontiers in Microbiology - April 8, 2019 Category: Microbiology Source Type: research

Recent Diagnosis Techniques in Pediatric Asthma
Objective measures of lung function are important in the diagnosis and management of asthma. Spirometry, the pulmonary function test most widely used in asthma, requires respiratory maneuvers that may be difficult for preschoolers. Impulse oscillometry (IOS) is a noninvasive method of measuring lung function during tidal breathing; hence, IOS is an ideal test for use in preschool asthma. Fractional exhaled nitric oxide (FeNO) levels correspond to eosinophilic inflammation and predict responsiveness to corticosteroids. Basic concepts of IOS, methodology, and interpretation, including available normative values, and recent f...
Source: Immunology and Allergy Clinics of North America - April 4, 2019 Category: Allergy & Immunology Authors: Karen M. McDowell Source Type: research

Novel trajectories for identifying asthma phenotypes: a longitudinal study in Korean asthma cohort, COREA
ConclusionTrajectory analysis is a novel method that provides longitudinal asthma phenotypes and aids in prediction of future risk of exacerbation. Further analysis is needed to validate the usefulness of these trajectories in an independent population.
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 20, 2019 Category: Allergy & Immunology Source Type: research

A Comparison of Atopy in Non-English versus English Speaking Asthmatics
Previous research has suggested that non-English speaking asthmatics have worse asthma control and pulmonary function test scores when compared to asthmatics that are fluent in English. The reason for this difference in asthma control between English and non-English speakers is likely multifactorial. In order to investigate possible contributors to the discrepancy in asthma control between these two populations, we sought to examine whether the degree of atopic disease is a significant contributing factor.
Source: Journal of Allergy and Clinical Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Maria Paula Henao, Faoud Ishmael Source Type: research

Lund-Mackay Computed Tomography Score Is Associated With Obstructive Pulmonary Function Changes in Chronic Cough Patients.
CONCLUSION: The patients with chronic cough frequently had paranasal sinus abnormalities. The Lund-Mackay CT score may be useful for assessing the condition of the lower airway in chronic cough patients. Upper airway examinations should play a part in the management of chronic cough. PMID: 30656950 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - January 18, 2019 Category: ENT & OMF Authors: Kariya S, Okano M, Higaki T, Tachibana T, Rikimaru T, Nishizaki K Tags: Am J Rhinol Allergy Source Type: research

Characteristics of Adult Severe Refractory Asthma in Korea Analyzed From the Severe Asthma Registry.
CONCLUSIONS: The baseline characteristics of severe asthma patients in the Korea Severe Asthma Registry were analyzed and reported for the first time. With this cohort, further prospective studies should be performed to search for ways to improve management of severe refractory asthma. PMID: 30479076 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 29, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research