Recent Diagnosis Techniques in Pediatric Asthma
Objective measures of lung function are important in the diagnosis and management of asthma. Spirometry, the pulmonary function test most widely used in asthma, requires respiratory maneuvers that may be difficult for preschoolers. Impulse oscillometry (IOS) is a noninvasive method of measuring lung function during tidal breathing; hence, IOS is an ideal test for use in preschool asthma. Fractional exhaled nitric oxide (FeNO) levels correspond to eosinophilic inflammation and predict responsiveness to corticosteroids. Basic concepts of IOS, methodology, and interpretation, including available normative values, and recent findings regarding FeNO are reviewed in this article.
Publication date: Available online 24 September 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Carlo Mümmler, Dieter Munker, Michaela Barnikel, Tobias Veit, Moritz Kayser, Tobias Welte, Jürgen Behr, Nikolaus Kneidinger, Hendrik Suhling, Katrin Milger
Publication date: Available online 24 September 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Alan P. Baptist, Desmond Lowe, Nadeen Sarsour, Hannah Jaffee, Sanaz Eftekhari, Laurie M. Carpenter, Priya Bansal
No one needs to wonder whether we have all become more stressed, more anxious, and even more depressed in the past 6 months amid the worst pandemic in over 100 years. Fear of infection with the possibility of illness and even death is accompanied by frustrations and anxieties over the adverse impact that this virus has had on our lives —personal and professional. Most of us are creatures of habit—we like what we like, the way we like it, and when we like it. In the beginning of the pandemic, we were all scared enough that when the shutdown occurred, most of us were more worried about ourselves, our families, an...
Evidence-based medicine has been the basis of much of our treatment patterns. The fact that it is based on population studies, although frequently with very restrictive stratifications of the patients being tested, is both its strength and weakness. Thus, for the treatment of a disease such as hypertension, good results may be observed for many, but likely not all, patients. Some patients may have specific gene mutations that alter their responsiveness to various treatments. Therefore, “personalized medicine,” whereby the individual patient’s signs and symptoms, responses to therapeutic interventions, and...
CONCLUSIONS: Our study suggests that in BPS patients' families, fibromyalgia and autoimmune diseases including asthma, and especially the non-allergic form of asthma, may be over-represented. PMID: 32964777 [PubMed - as supplied by publisher]