Perinatology & Neonatology Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Dissolvable microarray patches of levodopa and carbidopa for Parkinson's disease management
In conclusion, dissolving MAPs incorporating carbidopa and levodopa represent a promising alternative for improving the therapeutic management of Parkinson's disease.PMID:38663522 | DOI:10.1016/j.ejpb.2024.114304 (Source: European Journal of Pharmaceutics and Biopharmaceutics)
Source: European Journal of Pharmaceutics and Biopharmaceutics - April 25, 2024 Category: Drugs & Pharmacology Authors: Qonita Kurnia Anjani Natalia Moreno-Castellanos Yaocun Li Akmal Hidayat Bin Sabri Ryan F Donnelly Source Type: research

Mental Illness in the 2 Years Prior to Pregnancy in a Population With Traumatic Brain Injury: A Cross-Sectional Study: La maladie mentale dans les deux ans pr écédant une grossesse dans une population souffrant de lésion cérébrale traumatique : une étude transversale
CONCLUSIONS: Females with TBI, and especially those with a recent intentional TBI, have a high prevalence of mental illness before pregnancy. They may benefit from mental health screening and support in the post-injury, preconception, and perinatal periods.PMID:38659409 | DOI:10.1177/07067437241249957 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - April 25, 2024 Category: Psychiatry Authors: Hilary K Brown Rachel Strauss Kinwah Fung Andrea Mataruga Vincy Chan Tatyana Mollayeva Natalie Urbach Angela Colantonio Eyal Cohen Cindy-Lee Dennis Joel G Ray Natasha Saunders Simone N Vigod Source Type: research

The role of chest X-ray in the diagnosis of neonatal respiratory distress syndrome: a systematic review concerning low-resource birth scenarios
CONCLUSION: CXR remains an important diagnostic tool for NRDS. Despite its continued use in scientific reports, the findings suggest that the study's outcomes may not fully reflect the current global clinical practices, especially in low-resource settings where the early NRDS approach remains a challenge for neonatal survival.Trial registration: PROSPERO number CRD42022336480.PMID:38660779 | PMC:PMC11047214 | DOI:10.1080/16549716.2024.2338633 (Source: Global Health Action)
Source: Global Health Action - April 25, 2024 Category: International Medicine & Public Health Authors: Gabriela Silveira Neves Zilma Silveira Nogueira Reis Roberta Maia de Castro Romanelli Jannine Dos Santos Nascimento Andr é Dias Sanglard James Batchelor Source Type: research

A dual-channel electrochemical biosensor enables concurrent detection of pathogens and antibiotic resistance
Biosens Bioelectron. 2024 Apr 20;257:116314. doi: 10.1016/j.bios.2024.116314. Online ahead of print.ABSTRACTDiarrheagenic E. coli infections, commonly treated with β-lactam antibiotics, contribute to antibiotic resistance - a pressing public health concern. Rapid monitoring of pathogen antibiotic resistance is vital to combat antimicrobial spread. Current bacterial diagnosis methods identify pathogens or determine antibiotic resistance separately, necessitating multiple assays. There is an urgent need for tools that simultaneously identify infectious agents and their antibiotic resistance at the point of care (POC). We de...
Source: Biosensors and Bioelectronics - April 25, 2024 Category: Biotechnology Authors: Dharanivasan Gunasekaran Irina Rostovsky David Taussig Talya Bar-Am Yariv Wine Neta Sal-Man Sefi Vernick Source Type: research

Mutational spectrum of CFTR in cystic fibrosis patients with gastrointestinal and hepatobiliary manifestations
CONCLUSION: The study reports novel and reported variants in the CFTR gene in CF patients in Pakistani population having distinct phenotypes. It also emphasizes screening suspected Pakistani CF patients for the p. (Met1Thr) variant because of its increased observance and prevalence in the study. Moreover, the findings also signify searching for additional pathogenic variants in the genome of CF patients, which may modify the phenotypes. The findings contribute valuable information for the diagnosis, genetic counseling, and potential therapeutic strategies for CF patients in Pakistan.PMID:38662334 | DOI:10.1007/s11033-024-0...
Source: Molecular Biology Reports - April 25, 2024 Category: Molecular Biology Authors: Nadia Waheed Rehmana Waris Maryam Naseer Ayesha Razzaq Nighat Haider Abid Ali Shah Asmat Ullah Source Type: research

Impact of restrictive platelet transfusion strategies on transfusion rates: A cohort study in very preterm infants
DISCUSSION: Implementation of restrictive platelet guidelines led to reduction of the rate and number of platelet transfusions.PMID:38660945 | DOI:10.1111/trf.17844 (Source: Transfusion)
Source: Transfusion - April 25, 2024 Category: Hematology Authors: L E Heeger N A M Houben C Caram-Deelder S F Fustolo-Gunnink J G van der Bom E Lopriore Source Type: research

The role of chest X-ray in the diagnosis of neonatal respiratory distress syndrome: a systematic review concerning low-resource birth scenarios
CONCLUSION: CXR remains an important diagnostic tool for NRDS. Despite its continued use in scientific reports, the findings suggest that the study's outcomes may not fully reflect the current global clinical practices, especially in low-resource settings where the early NRDS approach remains a challenge for neonatal survival.Trial registration: PROSPERO number CRD42022336480.PMID:38660779 | DOI:10.1080/16549716.2024.2338633 (Source: Global Health Action)
Source: Global Health Action - April 25, 2024 Category: International Medicine & Public Health Authors: Gabriela Silveira Neves Zilma Silveira Nogueira Reis Roberta Maia de Castro Romanelli Jannine Dos Santos Nascimento Andr é Dias Sanglard James Batchelor Source Type: research

The Association Between Unintended Pregnancy and Perinatal Outcomes in Low ‐Risk Pregnancies: A Retrospective Registry Study in the Netherlands
This study used data (N = 9803) from a Dutch nationally representative registry of people with low-risk pregnancies receiving primary midwife-led care in the Netherlands between 2012 and 2020. Using logistic (mediation) regression analyses adjusted for potential confounders we investigated associations between unintended pregnancy and neonatal outcomes (low Apgar score, small for gestational age, and prematurity), parental morbidity (hypertension and gestational diabetes mellitus), and obstetric interventions (induction of labor, pain medication, assisted vaginal birth, and cesarean birth) and whether delayed initiation of...
Source: Journal of Midwifery and Women's Health - April 25, 2024 Category: Midwifery Authors: Amke M.G. van Tintelen, Danielle E.M.C. Jansen, Sophie H. Bolt, J. Catja Warmelink, Corine J. Verhoeven, Jens Henrichs Tags: RESEARCH ARTICLE Source Type: research

Exploring the resistome, virulome, and mobilome of multidrug-resistant Klebsiella pneumoniae isolates: deciphering the molecular basis of carbapenem resistance
Klebsiella pneumoniae, a notorious pathogen for causing nosocomial infections has become a major cause of neonatal septicemia, leading to high morbidity and mortality worldwide. This opportunistic bacterium has ... (Source: BMC Genomics)
Source: BMC Genomics - April 25, 2024 Category: Genetics & Stem Cells Authors: Sidra Rahmat Ullah, Sidra Irum, Iqra Mahnoor, Humaira Ismatullah, Mariam Mumtaz, Saadia Andleeb, Abdur Rahman and Muhsin Jamal Tags: Research Source Type: research

Performances of two rapid LAMP-based techniques for the intrapartum detection of Group B Streptococcus vaginal colonization
Group B Streptococcus (GBS) is the leading cause of invasive infections in newborns. The prevention of GBS neonatal disease relies on the administration of an intrapartum antibiotic prophylaxis to GBS-colonized w... (Source: Annals of Clinical Microbiology and Antimicrobials)
Source: Annals of Clinical Microbiology and Antimicrobials - April 25, 2024 Category: Microbiology Authors: Rym Charfi, C écile Guyonnet, Meiggie Untrau, Gaëlle Giacometti, Thierry Paper, Claire Poyart, Céline Plainvert and Asmaa Tazi Tags: Brief Report Source Type: research