Human Milk Cannabinoid Concentrations and Associations with Maternal Factors: The Lactation and Cannabis (LAC) Study
Breastfeeding Medicine, Ahead of Print. (Source: Breastfeeding Medicine)
Source: Breastfeeding Medicine - May 2, 2024 Category: Perinatology & Neonatology Authors: Elizabeth A. Holdsworth Anna Berim David R. Gang Janet E. Williams Caroline B. Smith Beatrice Caff é Olivia Brooks Celestina Barbosa-Leiker Mark A. McGuire Michelle K. McGuire Courtney L. Meehan Source Type: research

The spectrum of pneumonia among intubated neonates in the neonatal intensive care unit
Journal of Perinatology, Published online: 02 May 2024; doi:10.1038/s41372-024-01973-9The spectrum of pneumonia among intubated neonates in the neonatal intensive care unit (Source: Journal of Perinatology)
Source: Journal of Perinatology - May 2, 2024 Category: Perinatology & Neonatology Authors: Dayle J. Bondarev Rita M. Ryan Devashis Mukherjee Source Type: research

Examining the quality of care across the continuum of maternal care (antenatal, perinatal and postnatal care) under the expanded free maternity policy (Linda Mama Policy) in Kenya: a mixed-methods study
Conclusions Addressing the negative aspects of QoC while strengthening the positives is necessary to achieve the Universal Health Coverage goals through better quality service for every woman. (Source: BMJ Open)
Source: BMJ Open - May 2, 2024 Category: General Medicine Authors: Oyugi, B., Audi-Poquillon, Z., Kendall, S., Peckham, S. Tags: Open access, Health services research Source Type: research

Life-saving effect of pulmonary surfactant in premature babies
(Source: Journal of Clinical Investigation)
Source: Journal of Clinical Investigation - May 1, 2024 Category: Biomedical Science Authors: J. Usha Raj, Richard D. Bland, Jahar Bhattacharya, Marlene Rabinovitch, Michael A. Matthay Source Type: research

Adult and neonatal models of chemogenetic heart failure caused by oxidative stress
(Source: Journal of Clinical Investigation)
Source: Journal of Clinical Investigation - May 1, 2024 Category: Biomedical Science Authors: Fotios Spyropoulos, Apabrita Ayan Das, Markus Waldeck-Weiermair, Shambhu Yadav, Arvind K. Pandey, Ruby Guo, Taylor A. Covington, Venkata Thulabandu, Kosmas Kosmas, Benjamin Steinhorn, Mark A. Perrella, Xiaoli Liu, Helen Christou, Thomas Michel Source Type: research

Distributions of candidate vaccine Targets, virulence Factors, and resistance features of invasive group B Streptococcus using Whole-Genome Sequencing: A Multicenter, population-based surveillance study
CONCLUSIONS: The findings from this large whole-genome sequence of GBS isolates establish important baseline data required for further surveillance and evaluating the impact of future vaccine candidates.PMID:38692955 | DOI:10.1016/j.vaccine.2024.04.062 (Source: Vaccine)
Source: Vaccine - May 1, 2024 Category: Allergy & Immunology Authors: Wenjing Ji Haijian Zhou Jie Li Carl D Britto Zheliang Liu Wen Zhang Jiaxi Du Shabir A Madhi Gaurav Kwatra Ziyaad Dangor Zhengjiang Jin Hang Zhao Yifei Zhao Yu Fang Juan Li Source Type: research

Breast milk-mediated exposure to dioxins and antigen in infancy enhances antigen-specific antibody production capacity in adulthood in mice
J Toxicol Sci. 2024;49(5):209-218. doi: 10.2131/jts.49.209.ABSTRACTThe immune system is sensitive to many chemicals. Among dioxin compounds, 2,3,7,8-tetrachlorodizenzo-p-dioxin (TCDD) is the most toxic environmental pollutant. The effects of perinatal maternal exposure to dioxins may persist into childhood. However, there have been no reports to date on the effects of exposure to dioxins during infancy, when the immune organs are developing. Therefore, we investigated the effects of TCDD and antigen exposure during lactation on immune function, especially antibody production capacity, in adult mice. Beginning the day after...
Source: Journal of Toxicological Sciences - May 1, 2024 Category: Toxicology Authors: Hideki Kakutani Tomohiro Yuzuriha Teruyuki Nakao Source Type: research

Severe neonatal thrombocytopenia due to anti-HPA-4b alloantibodies: Third report described in a Caucasian mother
CONCLUSION: We described the third case of anti-HPA-4b alloantibody discovered in a Caucasian mother. This case strengthens the need for reference laboratory to genotype a panel of HPA alleles reflecting local genetic population diversity and for crossmatch of maternal serum with fresh paternal platelets in clinical suspected cases of neonatal alloimmune thrombocytopenia.PMID:38693097 | DOI:10.1111/trf.17863 (Source: Transfusion)
Source: Transfusion - May 1, 2024 Category: Hematology Authors: Rachel Petermann Fr édéric Bianchi Loubna Saib Nicolas Ferr é Nathalie Francelle Olivier Oudin Christophe Chenet Yasmine Mammasse Vincent Jallu Am élie Chaussade Antonin Cornu Laureline Dubray Agn ès Mailloux Source Type: research

Contribution of microglia to the epileptiform activity that results from neonatal hypoxia
Neuropharmacology. 2024 Apr 29:109968. doi: 10.1016/j.neuropharm.2024.109968. Online ahead of print.ABSTRACTMicroglia are described as the immune cells of the brain, their immune properties have been extensively studied since first described, however, their neural functions have only been explored over the last decade. Microglia have an important role in maintaining homeostasis in the central nervous system by surveying their surroundings to detect pathogens or damage cells. While these are the classical functions described for microglia, more recently their neural functions have been defined; they are critical to the matu...
Source: Neuropharmacology - May 1, 2024 Category: Drugs & Pharmacology Authors: Aisling Leavy Jessie Phelan Eva M Jimenez-Mateos Source Type: research

Distributions of candidate vaccine Targets, virulence Factors, and resistance features of invasive group B Streptococcus using Whole-Genome Sequencing: A Multicenter, population-based surveillance study
CONCLUSIONS: The findings from this large whole-genome sequence of GBS isolates establish important baseline data required for further surveillance and evaluating the impact of future vaccine candidates.PMID:38692955 | DOI:10.1016/j.vaccine.2024.04.062 (Source: Vaccine)
Source: Vaccine - May 1, 2024 Category: Allergy & Immunology Authors: Wenjing Ji Haijian Zhou Jie Li Carl D Britto Zheliang Liu Wen Zhang Jiaxi Du Shabir A Madhi Gaurav Kwatra Ziyaad Dangor Zhengjiang Jin Hang Zhao Yifei Zhao Yu Fang Juan Li Source Type: research

Breast milk-mediated exposure to dioxins and antigen in infancy enhances antigen-specific antibody production capacity in adulthood in mice
J Toxicol Sci. 2024;49(5):209-218. doi: 10.2131/jts.49.209.ABSTRACTThe immune system is sensitive to many chemicals. Among dioxin compounds, 2,3,7,8-tetrachlorodizenzo-p-dioxin (TCDD) is the most toxic environmental pollutant. The effects of perinatal maternal exposure to dioxins may persist into childhood. However, there have been no reports to date on the effects of exposure to dioxins during infancy, when the immune organs are developing. Therefore, we investigated the effects of TCDD and antigen exposure during lactation on immune function, especially antibody production capacity, in adult mice. Beginning the day after...
Source: Journal of Toxicological Sciences - May 1, 2024 Category: Toxicology Authors: Hideki Kakutani Tomohiro Yuzuriha Teruyuki Nakao Source Type: research

Severe neonatal thrombocytopenia due to anti-HPA-4b alloantibodies: Third report described in a Caucasian mother
CONCLUSION: We described the third case of anti-HPA-4b alloantibody discovered in a Caucasian mother. This case strengthens the need for reference laboratory to genotype a panel of HPA alleles reflecting local genetic population diversity and for crossmatch of maternal serum with fresh paternal platelets in clinical suspected cases of neonatal alloimmune thrombocytopenia.PMID:38693097 | DOI:10.1111/trf.17863 (Source: Transfusion)
Source: Transfusion - May 1, 2024 Category: Hematology Authors: Rachel Petermann Fr édéric Bianchi Loubna Saib Nicolas Ferr é Nathalie Francelle Olivier Oudin Christophe Chenet Yasmine Mammasse Vincent Jallu Am élie Chaussade Antonin Cornu Laureline Dubray Agn ès Mailloux Source Type: research

Contribution of microglia to the epileptiform activity that results from neonatal hypoxia
Neuropharmacology. 2024 Apr 29:109968. doi: 10.1016/j.neuropharm.2024.109968. Online ahead of print.ABSTRACTMicroglia are described as the immune cells of the brain, their immune properties have been extensively studied since first described, however, their neural functions have only been explored over the last decade. Microglia have an important role in maintaining homeostasis in the central nervous system by surveying their surroundings to detect pathogens or damage cells. While these are the classical functions described for microglia, more recently their neural functions have been defined; they are critical to the matu...
Source: Neuropharmacology - May 1, 2024 Category: Drugs & Pharmacology Authors: Aisling Leavy Jessie Phelan Eva M Jimenez-Mateos Source Type: research

Breast milk-mediated exposure to dioxins and antigen in infancy enhances antigen-specific antibody production capacity in adulthood in mice
J Toxicol Sci. 2024;49(5):209-218. doi: 10.2131/jts.49.209.ABSTRACTThe immune system is sensitive to many chemicals. Among dioxin compounds, 2,3,7,8-tetrachlorodizenzo-p-dioxin (TCDD) is the most toxic environmental pollutant. The effects of perinatal maternal exposure to dioxins may persist into childhood. However, there have been no reports to date on the effects of exposure to dioxins during infancy, when the immune organs are developing. Therefore, we investigated the effects of TCDD and antigen exposure during lactation on immune function, especially antibody production capacity, in adult mice. Beginning the day after...
Source: Journal of Toxicological Sciences - May 1, 2024 Category: Toxicology Authors: Hideki Kakutani Tomohiro Yuzuriha Teruyuki Nakao Source Type: research

Distributions of candidate vaccine Targets, virulence Factors, and resistance features of invasive group B Streptococcus using Whole-Genome Sequencing: A Multicenter, population-based surveillance study
CONCLUSIONS: The findings from this large whole-genome sequence of GBS isolates establish important baseline data required for further surveillance and evaluating the impact of future vaccine candidates.PMID:38692955 | DOI:10.1016/j.vaccine.2024.04.062 (Source: Vaccine)
Source: Vaccine - May 1, 2024 Category: Allergy & Immunology Authors: Wenjing Ji Haijian Zhou Jie Li Carl D Britto Zheliang Liu Wen Zhang Jiaxi Du Shabir A Madhi Gaurav Kwatra Ziyaad Dangor Zhengjiang Jin Hang Zhao Yifei Zhao Yu Fang Juan Li Source Type: research