Severe neonatal thrombocytopenia due to anti-HPA-4b alloantibodies: Third report described in a Caucasian mother

CONCLUSION: We described the third case of anti-HPA-4b alloantibody discovered in a Caucasian mother. This case strengthens the need for reference laboratory to genotype a panel of HPA alleles reflecting local genetic population diversity and for crossmatch of maternal serum with fresh paternal platelets in clinical suspected cases of neonatal alloimmune thrombocytopenia.PMID:38693097 | DOI:10.1111/trf.17863

Source: Transfusion - May 1, 2024 Category: Hematology Authors: Rachel Petermann Fr édéric Bianchi Loubna Saib Nicolas Ferr é Nathalie Francelle Olivier Oudin Christophe Chenet Yasmine Mammasse Vincent Jallu Am élie Chaussade Antonin Cornu Laureline Dubray Agn ès Mailloux Source Type: research