Anxiety Levels in Brazilian Women with Metastatic Breast Cancer Undergoing Palliative Chemotherapy: A Prospective Study
CONCLUSION: Women with breast cancer undergoing palliative chemotherapy exhibited high trait-anxiety scores, which decreased significantly over the course of treatment.PMID:38679972 | DOI:10.31557/APJCP.2024.25.4.1135 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Larissa Marcondes Leonel Dos Santos Silva Cristiano De Oliveira Ribeiro Natalia Naome Oshiro Luciana De Alcantara Nogueira Paulo Ricardo Bittencourt Guimaraes Luciana Puchalski Kalinke Source Type: research
Autologous platelet-rich plasma for assisted reproduction
CONCLUSIONS: We are uncertain about the effect of intrauterine or intraovarian administration of PRP on outcomes of assisted reproduction technology in infertile women. The pooled results should be interpreted with caution. Only one of the 12 included studies was judged at low risk of bias. Other limitations of the included trials were failure to report live birth, poor reporting of methods, lack of prospective protocol registration, low precision due to the small number of enrolled participants, indirectness due to the specific subpopulations and settings studied, and insufficient or absent safety data.PMID:38682756 | PMC...
Source: Cochrane Database of Systematic Reviews - April 29, 2024 Category: General Medicine Authors: Dennis Vaidakis Michail Papapanou Charalampos S Siristatidis Source Type: research
Anxiety Levels in Brazilian Women with Metastatic Breast Cancer Undergoing Palliative Chemotherapy: A Prospective Study
CONCLUSION: Women with breast cancer undergoing palliative chemotherapy exhibited high trait-anxiety scores, which decreased significantly over the course of treatment.PMID:38679972 | DOI:10.31557/APJCP.2024.25.4.1135 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Larissa Marcondes Leonel Dos Santos Silva Cristiano De Oliveira Ribeiro Natalia Naome Oshiro Luciana De Alcantara Nogueira Paulo Ricardo Bittencourt Guimaraes Luciana Puchalski Kalinke Source Type: research
The Potential Role of Phytochemicals of < em > Juniperus procera < /em > in the Treatment of Ovarian Cancer and the Inhibition of Human Topoisomerase II Alpha Activity
Bioinform Biol Insights. 2024 Apr 25;18:11779322241248904. doi: 10.1177/11779322241248904. eCollection 2024.ABSTRACTA variety of active chemicals found in medicinal plants can be used to develop new medications with few adverse effects. In vitro and in silico analyses were used to evaluate the anticancer properties of Juniperus procera fruit and leaf extracts. Here, we show that the methanolic extract from J procera fruit and leaf extracts inhibits 2 human ovarian cancer cell lines, A2780CP and SKOV-3. The leaf extract demonstrated strong cytotoxicity against A2780CP with an IC50 of 1.2 μg/mL, almost matching the IC50 of ...
Source: Bioinformatics and Biology Insights - April 29, 2024 Category: Bioinformatics Authors: Ateeq A Al-Zahrani Source Type: research
Expression of Concern: Circular RNA S-7 promotes ovarian cancer EMT via sponging miR-641 to upregulate ZEB1 and MDM2
Biosci Rep. 2024 May 29;44(5):BSR-2020-0825_EOC. doi: 10.1042/BSR-2020-0825_EOC.NO ABSTRACTPMID:38682476 | DOI:10.1042/BSR-2020-0825_EOC (Source: Bioscience Reports)
Source: Bioscience Reports - April 29, 2024 Category: Biomedical Science Source Type: research
The Effect of Thiazolidinediones in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
CONCLUSION: Both pioglitazone and rosiglitazone were associated with significant increases in body weight and BMI when compared with metformin or placebo. Pioglitazone significantly reduced triglycerides and fasting insulin when compared with placebo while rosiglitazone showed a modest reduction of LH when compared with metformin.PROSPERO REGISTRATION NO: CRD42020178783.PMID:38683294 | DOI:10.1007/s12325-024-02848-3 (Source: Adv Data)
Source: Adv Data - April 29, 2024 Category: Epidemiology Authors: Mohammed A Abdalla Najeeb Shah Harshal Deshmukh Amirhossein Sahebkar Linda Östlundh Rami H Al-Rifai Stephen L Atkin Thozhukat Sathyapalan Source Type: research
Identification of MAD2L1 and BUB1B as Potential Biomarkers Associated with Progression and Prognosis of Ovarian Cancer
This study aimed to investigate the molecular mechanisms underlying the development of ovarian cancer and identify novel tumor biomarkers for the diagnosis and prognosis of ovarian cancer. Three databases containing gene expression profiles specific to serous ovarian cancer (GSE18520, GSE12470, and GSE26712) were acquired. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes were analyzed for the differentially expressed gene (DEGs). The protein-protein interaction (PPI) network was constructed using the STRING database. The pivotal genes in the PPI network were screened using the Cytoscape software. Survival curve an...
Source: Biochemical Genetics - April 29, 2024 Category: Genetics & Stem Cells Authors: Rongrong Tang Jinfei Tong Shanliang Shang Guangxiao Li Fangying Sun Xiaojing Guan Jianhua Yang Source Type: research
Autologous platelet-rich plasma for assisted reproduction
CONCLUSIONS: We are uncertain about the effect of intrauterine or intraovarian administration of PRP on outcomes of assisted reproduction technology in infertile women. The pooled results should be interpreted with caution. Only one of the 12 included studies was judged at low risk of bias. Other limitations of the included trials were failure to report live birth, poor reporting of methods, lack of prospective protocol registration, low precision due to the small number of enrolled participants, indirectness due to the specific subpopulations and settings studied, and insufficient or absent safety data.PMID:38682756 | PMC...
Source: Cochrane Database of Systematic Reviews - April 29, 2024 Category: General Medicine Authors: Dennis Vaidakis Michail Papapanou Charalampos S Siristatidis Source Type: research
Anxiety Levels in Brazilian Women with Metastatic Breast Cancer Undergoing Palliative Chemotherapy: A Prospective Study
CONCLUSION: Women with breast cancer undergoing palliative chemotherapy exhibited high trait-anxiety scores, which decreased significantly over the course of treatment.PMID:38679972 | DOI:10.31557/APJCP.2024.25.4.1135 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Larissa Marcondes Leonel Dos Santos Silva Cristiano De Oliveira Ribeiro Natalia Naome Oshiro Luciana De Alcantara Nogueira Paulo Ricardo Bittencourt Guimaraes Luciana Puchalski Kalinke Source Type: research
The Information Technology (IT) Infrastructure of the Multicenter Archipelago of Ovarian Cancer Research Biobank: A Potential Blueprint for Other Biobanks
Conclusion: The IT infrastructure of the AOCR biobank represents a new standard for biobanks, offering flexibility to handle diverse diseases and types of biomaterials. This infrastructure bypasses the need for disease-specific, custom-built software, thereby being cost- and time-effective while ensuring data quality and legislative compliance. The adaptability of this infrastructure highlights its potential to serve as a blueprint for the development of IT infrastructures in both new and existing biobanks.PMID:38682281 | DOI:10.1089/bio.2023.0118 (Source: Biopreservation and Biobanking)
Source: Biopreservation and Biobanking - April 29, 2024 Category: Biomedical Science Authors: Hein S Zelisse Sander de Ridder Mignon D J M van Gent Constantijne H Mom G Bea A Wisman Eva-Maria Roes Anna K L Reyners Jurgen M Piek Gatske M Nieuwenhuyzen-de Boer Christianne A R Lok Cornelis D de Kroon Loes F S Kooreman Marc-Jan Janssen Maurice Phm Jan Source Type: research
Optimal human ovarian follicle isolation: A review focused on enzymatic digestion
Histol Histopathol. 2024 Apr 12:18747. doi: 10.14670/HH-18-747. Online ahead of print.ABSTRACTThe damage or depletion of ovarian reserves due to aging or cancer treatment can increase the need for fertility preservation techniques. One of the most common ways of supporting fertility in prepubertal girls and women who require immediate cancer treatment is through ovarian tissue cryopreservation and re-transplantation following cancer treatment. However, a more appropriate method should be employed in diseases such as leukemia, where malignant cells may be present in cryopreserved tissue, instead of ovarian tissue transplant...
Source: Histology and Histopathology - April 29, 2024 Category: Cytology Authors: Farnaz Tajbakhsh Somayeh Tavana Mohammad Kazemi Ashtiani Christiani Andrade Amorim Rouhollah Fathi Source Type: research
Correction: TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2
J Ovarian Res. 2024 Apr 29;17(1):93. doi: 10.1186/s13048-024-01418-z.NO ABSTRACTPMID:38685112 | DOI:10.1186/s13048-024-01418-z (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Yali Fan Shuya Chen Chunfang Chu Xiaodan Yin Jing Jin Lingyan Zhang Huihui Yan Zheng Cao Ruixia Liu Mingwei Xin Lin Li Chenghong Yin Source Type: research
A novel defined programmed cell death related gene signature for predicting the prognosis of serous ovarian cancer
CONCLUSION: GNA15 emerged as an independent and excellent prognostic marker for SOC patients. This study provides valuable insights into the prognostic potential of DEPCDGs in SOC, presenting new avenues for personalized treatment strategies.PMID:38685095 | DOI:10.1186/s13048-024-01419-y (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Feng Zhan Yina Guo Lidan He Source Type: research
