Possible Balo concentric sclerosis : MRI
Case Report: 23 year old left hemiparesis. Clinical diagnosis MS. CSF OCB positive . Poor response to steroid. CEMR images are provided.MRI images reveal rounded lesion with alternating layers of increased and reduced signal, along with diffusion restriction. Case Submitted by Dr Rahul Rajeev, DM (Neurology std)Quick Notes: Balo concentric sclerosis is a rare and severe monophasic demyelinating disease, considered a subtype of multiple sclerosis, appearing as a rounded lesion with alternating layers of increased and reduced signal giving it a characteristic 'bulls eye or 'onion bulb' a...
Source: Sumer's Radiology Site - March 29, 2018 Category: Radiology Authors: Sumer Sethi Source Type: blogs
Fight Aging! Newsletter, March 26th 2018
In conclusion, senescence of vascular cells promotes the development of age-related disorders, including heart failure, diabetes, and atherosclerotic diseases, while suppression of vascular cell senescence ameliorates phenotypic features of aging in various models. Recent findings have indicated that specific depletion of senescent cells reverses age-related changes. Although the biological networks contributing to maintenance of homeostasis are extremely complex, it seems reasonable to explore senolytic agents that can act on specific cellular components or tissues. Several clinical trials of senolytic agents are currentl...
Source: Fight Aging! - March 25, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Pre-death Rally or True Health Improvement: It ’s Difficult to Know
Dear Carol: My mom has had Multiple Sclerosis (MS) for 30 years and is nearing the end of her life. She lives in a nursing home and I visit daily. Mom’s been struggling to swallow and has been sick with a urinary tract infection (UTI). Sometimes she's even thought that my dad, who died two years ago, is with her. She was eating and drinking little and was anxious. Two days ago, the staff told me that this could be the beginning of the end, and the time for comfort care may be coming, but they wanted to try a different antibiotic, a sedative to calm her, and a small amount of morphine for pain before mak...
Source: Minding Our Elders - March 25, 2018 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Failed ACA Reinsurance Program Shows: Government Subsidies Don't Reduce Premiums
ObamaCare turns eight years old today. Some opponents had hoped to mark the occasion by giving supporters the birthday gift they ’ve always wanted: a GOP-sponsored bailout of ObamaCare-participating private insurance companies. Fortunately, a dispute over subsidies for abortion providers killed what could have been the first of many GOP ObamaCare bailouts.ObamaCare premiums have been skyrocketing. All indications are this will continue in 2019, with insurers announcing premium increases up to32 percent or more just before this year ’s mid-term elections. Some Republicans fear voters will punish them for the effects o...
Source: Cato-at-liberty - March 23, 2018 Category: American Health Authors: Michael F. Cannon Source Type: blogs
An Update on Immune System Recreation as a Treatment for Multiple Sclerosis
The destruction of near all immune cells followed by cell therapy to speed recreation of the immune system is a fairly harsh procedure, as the only way to clear a sufficiently high fraction of immune cells at the moment is essentially a form of chemotherapy. It is an effective treatment for autoimmune conditions, however, albeit with a significant risk of death, in line with that for many major surgeries. This makes it suitable in its current form only for more severe autoimmune disorders in which the patients tend to be younger and more robust, but with a very poor prognosis. In past years researchers have demonstrated co...
Source: Fight Aging! - March 20, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Notes from WIRED Health 2018 at Francis Crick Institute
Set in its new home of the Francis Crick Institute, WIRED Health 2018 brought together world leaders and change-makers in cancer, aging, artificial intelligence, government, medical devices, and pharmaceuticals, to name but a few. Alongside the main event, cutting-edge medtech companies demonstrated their new technologies, and budding start-ups pitched for the chance to be crowned WIRED Health start-up of the year.
Bruce Levine from the University of Pennsylvania opened the day by setting the challenge of how to treat a condition like cancer, which is fundamentally the result of “our own bodies gone awry.” Bruce intro...
Source: Medgadget - March 16, 2018 Category: Medical Devices Authors: Tom Peach Tags: Exclusive Source Type: blogs
Physically Fit Women Nearly 90 Percent Less Likely to Develop Dementia
Women with high physical fitness at middle age were nearly 90 percent less likely to develop dementia according to a new study.byAlzheimer's Reading RoomThe information in this study is significant.An important finding of the study is thatwhen highly fit women did develop dementia, they developed the disease an average of 11 years later than women who were moderately fit, or at age 90 instead of age 79.Previous studies indicate that if the onset of Alzheimer's could be delayed to the age of 90,the number of people living with dementia would be cut in half.Currently,at age 80 there is a thirty percent of being diagnosed wit...
Source: Alzheimer's Reading Room, The - March 15, 2018 Category: Neurology Tags: alzheimer care alzheimers alzheimers research alzheimers statistics care of dementia patients dementia care exercise fitness women Source Type: blogs
What Does Your Handedness Say About Your Brain Structure?
Left-handedness, as a relatively uncommon phenomenon, never fails to fascinate people. There is a common perception that left-handed people are more talented and artistic. To what extent these assumptions are correct, and what your preferred use of right or left hand can tell you about your brain structure?
Handedness represents the better performance or preference of using one hand, i.e., the dominant hand. Right-handedness is the most common type observed in 70–95% of the world population, followed by left-handedness, and then a very rare type of mixed handedness and ambidexterity. Although this is an important physio...
Source: World of Psychology - March 13, 2018 Category: Psychiatry & Psychology Authors: Psych Central Staff Tags: Brain and Behavior Brain Blogger Publishers Brain Structure Handedness left-handed right-handed Source Type: blogs
Robotics, A.I. and Blockchain Redesign The Pharma Supply Chain
Exoskeletons will aid pharma factory workers. 3D printing will allow pharmacies to produce drugs on the spot. Blockchain technologies will help fight counterfeit drugs. These are just bits and pieces, but the entire process of the pharmaceutical supply chain will be affected by disruptive technologies. Let me show you a comprehensive overview how innovations will make it more efficient, faster and cheaper than ever before.
Exoskeletons will aid pharma factory workers. 3D printing will allow pharmacies to produce drugs on the spot. Blockchain technologies will help fight counterfeit drugs. These are just bits and pieces, b...
Source: The Medical Futurist - March 13, 2018 Category: Information Technology Authors: nora Tags: 3D Printing in Medicine Artificial Intelligence in Medicine Future of Pharma Security & Privacy AI blockchain digital Innovation Personalized medicine pharmaceutics pharmacies robotics robots supply chain Source Type: blogs
Does Vitamin D Deficiency Contribute to Brain Disorders?
In this study published in July 2017, researchers looked at the vitamin D levels and cognitive function in patients who experienced psychosis. They found an association between low levels of vitamin D and decreased processing speed and verbal fluency. The authors suggested the next step should be randomized controlled trials of vitamin D supplementation in those with psychosis and vitamin D deficiency.
Another study, published in Psychiatry Research in August 2017, looked at whether vitamin B12, homocysteine folic acid, and vitamin D might be connected to childhood obsessive-compulsive disorder (OCD). Fifty-two children an...
Source: World of Psychology - February 17, 2018 Category: Psychiatry & Psychology Authors: Janet Singer Tags: Alternative and Nutritional Supplements Brain and Behavior Health-related Memory and Perception Mental Health and Wellness Brain Disorder Mental Illness Vitamin D Vitamin Deficiency Source Type: blogs
Congress Repeals Medicare Therapy Caps and Lifts Limits on Speech-Generating Devices
Congress has permanently repealed Medicare Part B therapy caps and permanently extended the Steve Gleason Enduring Voices Act, which authorizes the purchase of speech-generating devices (SGDs).
The measures were included in a continuing resolution passed yesterday that funds the federal government for the next two years.
Medicare Part B Therapy Cap
The resolution permanently eliminates the hard cap on how much outpatient speech-language, occupational and physical therapy each Medicare beneficiary is allowed per year. Congress has allowed an exceptions process in most of the past 20 years, but this permanent fix repeals the...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - February 9, 2018 Category: Speech-Language Pathology Authors: Jeffrey Regan Tags: Advocacy Audiology Speech-Language Pathology Augmentative Alternative Communication Technology Source Type: blogs
Halo Neuroscience raises $13M to further develop and commercialize neuromodulation headset aimed at inducing “hyperplasticity”
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Halo Neuroscience raises $13m in Series B (Mass Device):
“Neurostimulation device maker Halo Neuroscience said today it raised $13 million in a Series B round of financing to support its Halo Sport neurostim headset designed to improve muscle memory acquisition from athletic training.
The funding round was led by TPG and joined by existing investors Lux Capital, JAZZ Venture Partners and XFund, the San Francisco-based company said…
The company’s flagship device, the Halo Sport, is designed to deliver neurostimulation to the motor cortex in a 20 minute neuropriming session which Halo Neuroscience claims induces a ...
Source: SharpBrains - February 2, 2018 Category: Neuroscience Authors: SharpBrains Tags: Cognitive Neuroscience Health & Wellness Technology Halo Neuroscience Halo Sport headset hyperplasticity neuromodulation neuropriming neurostimulation Source Type: blogs
Swallowing Impairment Needn't Mark the End of Great Eating
Dysphagia is a swallowing impairment that can occur after someone has a stroke or any type of brain injury. Dysphagia is also a concern with Parkinson’s disease, multiple sclerosis (MS), oral cancer, and many other injuries and diseases. However, according to the National Institutes of Health (NIH), dysphagia is also a growing concern in Alzheimer’s Disease (AD). The NIH says that dysphagia “frequently leads to aspiration pneumonia, a common cause of death in this population, particularly in the later stage of AD.”
Read full article on HealthCentral about how to prepare food for swallowing disorders:
Purchase Mindi...
Source: Minding Our Elders - January 29, 2018 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Swallowing Impairment Needn't Mark the End of Tasty Food
Dysphagia is a swallowing impairment that can occur after someone has a stroke or any type of brain injury. Dysphagia is also a concern with Parkinson’s disease, multiple sclerosis (MS), oral cancer, and many other injuries and diseases. However, according to the National Institutes of Health (NIH), dysphagia is also a growing concern in Alzheimer’s Disease (AD). The NIH says that dysphagia “frequently leads to aspiration pneumonia, a common cause of death in this population, particularly in the later stage of AD.” Free recipes in this article and free downloads, as well.
Read full article on HealthCentral about ho...
Source: Minding Our Elders - January 29, 2018 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Fight Aging! Newsletter, January 29th 2018
In conclusion, the present study demonstrated that TIGIT is a prominent negative immune regulator involved in immunosenescence. This novel finding is highly significant, as targeting TIGIT might be an effective strategy to improve the immune response and decrease age-related comorbidities.
Delivery of Extracellular Vesicles as a Potential Basis for Therapies
https://www.fightaging.org/archives/2018/01/delivery-of-extracellular-vesicles-as-a-potential-basis-for-therapies/
Here I'll point out a readable open access review paper on the potential use of extracellular vesicles as a basis for therapy: harvest...
Source: Fight Aging! - January 28, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
