Cytomegalovirus Harmfully Alters Immune Cell Populations in the Aging Immune System
The aging of the immune system isn't just a matter of becoming vulnerable to commonplace infectious diseases, such as influenza. The immune system also removes senescent cells and cancerous cells, both of which present sizable risks to health in later life. Additionally, immune cells participate in normal tissue maintenance in a variety of ways. Further, the chronic inflammation characteristic of an aged immune system disrupts the normal function of many types of cell and tissue, contributing to a diverse range of age-related conditions.
For most people, cytomegalovirus (CMV) is an apparently innocuous persistent he...
Source: Fight Aging! - December 6, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Tips for Traveling with Mobility Limitations Along with Incontinence
Traveling with conditions like multiple sclerosis (MS) or rheumatoid arthritis (RA) can be challenging, particularly when mobility is a serious concern. Add incontinence to that - something that is quite common with MS - and the challenge increases. Yet, it can be done. It takes research and careful planning like this couple did but they made it work last summer. Start planning your trip for spring!
Read more about traveling with extra challenges like incontinence on Egosancares blog:
Minding Our Elders: Caregivers Share Their Personal Stories. “I hold onto your book as a life preserver and am reading it slowly on purpos...
Source: Minding Our Elders - December 3, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Food Intolerances: A Warning of Bad Things Ahead
I’ve recently discussed how the majority of food intolerances, whether to FODMAPs, histamine, nightshades, fructose, etc., are really manifestations of dysbiosis and SIBO. Here is another way to view these phenomena: Food intolerances are your body’s signal to you that serious deterioration in your health is coming.
In other words, if all you do is choose to reduce or eliminate the offending food, you are still left with the massive disruption of your intestinal microbiome that caused the food intolerance in the first place, along with increased intestinal permeability and endotoxemia. So say you eliminate ferm...
Source: Wheat Belly Blog - November 1, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open microbiota prebiotic probiotic sibo small intestinal bacterial super gut undoctored wheat belly Source Type: blogs
Merck, GlaxoSmithKline, AbbVie, Sanofi & Bristol Myers Squibb: Big Pharma ’s Extending Digital Health Reaches
A few weeks ago, we kickstarted a new series of articles contemplating the moves of pharmaceutical heavyweights in the digital health arena. The first batch of companies, Johnson & Johnson, Pfizer, Bayer and Novartis, seem to have some interest in remote healthcare solutions and DTx.
In this second article, we will explore which trends pharma giants Merck, GlaxoSmithKline, AbbVie, Sanofi and Bristol Myers Squibb are eyeing.
Merck: big tech-friendly
A big pharma company itself, Germany’s Merck hasn’t shied from teaming up with big tech companies in recent years as it aims to make a lasting footpri...
Source: The Medical Futurist - October 26, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine Biotechnology Future of Medicine Future of Pharma Health Sensors & Trackers Personalized Medicine Portable Medical Diagnostics Security & Privacy pharmaceutics 23andme philips big pharma Merck Source Type: blogs
Husband Criticized for How He Cares for Wife with Dementia
Dementia caregiving can be a wild ride on a rollercoaster. The last thing the caregiver needs is outsiders making un-educated guesses and giving "helpful" advice about something that is not their concern. This husband also has family members who disagree with his choices but he is doing what works for them so shouldn't he be left alone?
Read more of their spousal caregiving story on Egosancares and see what you think:
Minding Our Elders: Caregivers Share Their Personal Stories. “I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.” ...Craig William Dayton,...
Source: Minding Our Elders - October 20, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Celebrate World Menopause Month with Education
Why is there such a stigma concerning menopause? It's a natural process that all women who live long enough will go through. Many actually welcome the cessation of their periods, but others dread it as a sign that they are getting "old." As with most things, the more you know about a topic the better so if you'd like to learn a little more about menopause - or just celebrate the awareness of this month - read more on the Egosancares blog:
Minding Our Elders: Caregivers Share Their Personal Stories. “I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.”�...
Source: Minding Our Elders - October 18, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Incontinence Battles with Parent Living with Dementia Ruining Relationship
Many well-meaning families move a parent who shows signs of dementia into their home feeling that this arrangement makes it possible to provide the best care. For some, especially those who are willing to learn how to work with people living with dementia in ways that can smooth out the tough areas, this works out well all the way through. Many, however, can make it work until complete incontinence becomes an issue. This is a big challenge because the incontinence person is incapable of understanding their own incontinence.
Read more on Egosancares about this couple and their frustration with dementia and incontinen...
Source: Minding Our Elders - October 15, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Traveling with Incontinence As Well As Multiple Sclerosis a Challenge
Traveling with MS can be challenging. Traveling with incontinence can be challenging. Traveling with both? Oh, yeah - lots of challenges. But it can be done with careful planning.
Read more on Egosancares blog about how we advised this couple to handle the double challenges
Minding Our Elders: Caregivers Share Their Personal Stories. “I hold onto your book as a life preserver and am reading it slowly on purpose...I don't want it to end.” ...Craig William Dayton, Film Composer
Request a free sample from Egosancares.com
Need incontinence support for yourself or someone else? Try Egosan’s Incontinence...
Source: Minding Our Elders - October 14, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Caregiving During Middle Age Inspired Author to Start Foundation to Help Caregivers
When people think about caregiving spouses, they often think of older adults. We only have to look at a young mother diagnosed with multiple sclerosis (MS), a young husband diagnosed with rheumatoid arthritis (RA), or in this case, a woman whose healthy husband had a sudden, massive stroke, to know differently. Kathi Koll, author of “Kick-Ass Kinda Girl: A Memoir of Life, Love, and Caregiving” knows the drill. She and her husband, Don, lived a life of glitz and glamour, working and playing alongside friends who were celebrities and politicians...
Continue reading on HealthCentral for more about Kathi Koll's foundation:...
Source: Minding Our Elders - October 8, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
EvoWalk Digital Therapy Platform: Interview with Pierluigi Mantovani, CEO at Evolution Devices
Evolution Devices, a company based in California, created a functional electrical stimulation device to assist people with foot drop to walk more freely. Foot drop is caused by muscle weakness/paralysis, and those affected struggle to lift the front part of their foot, which makes walking difficult and can lead to falls.
The product is called EvoWalk, and it consists of an electrical stimulation device that stimulates muscles in the leg that can lift the foot at exactly the right time during walking. The device gathers data on patient activity which can be monitored by a physical therapist remotely and during in-per...
Source: Medgadget - October 5, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Neurology Rehab evolutiondevices evowalk Source Type: blogs
Christina Applegate reveals multiple sclerosis diagnosis
Award-winning actress Christina Applegate revealed on social media that she had been diagnosed with multiple sclerosis (MS). “It’s been a tough road. But as we all know, the road keeps going,” wrote Applegate in a tweet. Multiple sclerosis is a neurological autoimmune disease that has puzzled patients and health care providers for decades. The diseaseRead more …Christina Applegate reveals multiple sclerosis diagnosis originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - August 25, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/yasir-jassam" rel="tag" > Yasir Jassam, MD < /a > < /span > Tags: Conditions Neurology Source Type: blogs
Fight Aging! Newsletter, August 16th 2021
In conclusion, cancer survivors, especially older individuals, demonstrate greater odds of and accelerated functional decline, suggesting that cancer and/or its treatment may alter aging trajectories.
Linking Particulate Air Pollution and Dementia in a Small Region of the US
https://www.fightaging.org/archives/2021/08/linking-particulate-air-pollution-and-dementia-in-a-small-region-of-the-us/
It is fairly settled that evident particulate air pollution, such as daily exposure to smoke from wood-fueled cooking fires, has a strongly detrimental effect on long-term health. The mechanisms involved are inflam...
Source: Fight Aging! - August 15, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Linking TDP-43 Dysfunction, Cholesterol, and Maintenance of Myelin in Neurodegeneration
TDP-43 is one of the few proteins in the body that can misfold in ways that lead to solid aggregates that disrupt cell and tissue function. The biochemistry and relevance of TDP-43 is a more recent area of research in comparison to the study of, say, amyloid-β in Alzheimer's disease and α-synuclein in Parkinson's disease, but it appears important to the progression of a number of neurodegenerative conditions. Researchers here elaborate on the relationship between TDP-43 and age-related demyelination, the corrosion of myelin sheathing around axons that is necessary for nervous system function, normally maintained by a pop...
Source: Fight Aging! - August 11, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, August 9th 2021
In conclusion, the present study supports that some age-related diseases as well as education are causally related to longevity and highlights several new targets for achieving longevity, including management of venous thromboembolism, appropriate intake of sugar, and control of body fat. Our results warrant further studies to elucidate the underlying mechanisms of these reported causal associations.
Pol III Inhibition Extends Longevity in Short-Lived Species
https://www.fightaging.org/archives/2021/08/pol-iii-inhibition-extends-longevity-in-short-lived-species/
As this paper notes, Pol III is downstrea...
Source: Fight Aging! - August 8, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Oligodendrocytes and their Progressive Failure to Ensure Myelination in the Aging Brain
Axons that connect neurons in the nervous system are sheathed in structures largely made of myelin. This myelin sheath is necessary for the correct function of nerves and the brain, as demonstrated by the unpleasant consequences of demyelinating conditions such as multiple sclerosis. In normal aging there is a lesser degree of loss of myelin over time, and a weight of evidence points towards this loss providing a meaningful contribution to age-related cognitive decline. Therefore it is worth keeping an eye on this area of research, and the development of therapies for demyelinating conditions, as some approaches might also...
Source: Fight Aging! - August 3, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
