Comparative study on the occurrence of adverse effects in the concomitant use of azathioprine and aldehyde oxidase inhibitors
CONCLUSION: Concomitant use of AO inhibitors increased the signals for AZA-induced adverse effects. To date, no studies have evaluated the clinical importance of AO as a drug-metabolizing enzyme, and further in vitro and clinical research is needed to clarify the contribution of AO to the pharmacokinetics of thiopurines.PMID:38097359 | DOI:10.1080/14740338.2023.2295976 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - December 14, 2023 Category: Drugs & Pharmacology Authors: Hinata Ueda Katsuya Narumi Shuho Asano Yoshitaka Saito Ayako Furugen Masaki Kobayashi Source Type: research
Molecules, Vol. 28, Pages 8079: Water-Soluble Polyoxometal Clusters of Molybdenum (V) with Pyrazole and Triazole: Synthesis and Study of Cytotoxicity and Antiviral Activity
Michael A. Shestopalov
Among well-studied and actively developing compounds are polyoxometalates (POMs), which show application in many fields. Extending this class of compounds, we introduce a new subclass of polyoxometal clusters (POMCs) [Mo12O28(μ-L)8]4− (L = pyrazolate (pz) or triazolate (1,2,3-trz or 1,2,4-trz)), structurally similar to POM, but containing binuclear Mo2O4 clusters linked by bridging oxo- and organic ligands. The complexes obtained by ampoule synthesis from the binuclear cluster [Mo2O4(C2O4)2(H2O)2]2− in a melt of an organic ligand are soluble and stable in...
Source: Molecules - December 14, 2023 Category: Chemistry Authors: Anna V. Konkova Iulia V. Savina Darya V. Evtushok Tatiana N. Pozmogova Maria V. Solomatina Alina R. Nokhova Alexander Y. Alekseev Natalia V. Kuratieva Ilia V. Eltsov Vadim V. Yanshole Aleksander M. Shestopalov Anton A. Ivanov Michael A. Shestopalov Tags: Article Source Type: research
Neutral Chromium Complex with a Cr ≡Si Triple Bond: Synthesis and Photoinduced H-H and Benzene C-H Bond Activation
Chemistry. 2023 Dec 13:e202303765. doi: 10.1002/chem.202303765. Online ahead of print.ABSTRACTA neutral silylyne complex with a Cr≡Si triple bond was prepared by dehydrogenation of a chromium silylene complex with Cr-H and Si-H bonds, and was isolated as monomeric crystals, unlike dimeric forms of its tungsten and molybdenum congeners. The strong Cr(δ-)-Si(δ +) bond polarity was revealed by the reaction with MeOH and DFT calculations. The chromium silylyne complex reacted with H2 under LED (365 nm) irradiation to reproduce the precursor silylene complex with a (H)Cr=Si(H) moiety, as a result of 1,2-H-H addition across ...
Source: Chemistry - December 13, 2023 Category: Chemistry Authors: Masahiro Matsuoka Koichi Nagata Ryoma Ohno Tsukasa Matsuo Hiromi Tobita Hisako Hashimoto Source Type: research
Neutral Chromium Complex with a Cr ≡Si Triple Bond: Synthesis and Photoinduced H-H and Benzene C-H Bond Activation
Chemistry. 2023 Dec 13:e202303765. doi: 10.1002/chem.202303765. Online ahead of print.ABSTRACTA neutral silylyne complex with a Cr≡Si triple bond was prepared by dehydrogenation of a chromium silylene complex with Cr-H and Si-H bonds, and was isolated as monomeric crystals, unlike dimeric forms of its tungsten and molybdenum congeners. The strong Cr(δ-)-Si(δ +) bond polarity was revealed by the reaction with MeOH and DFT calculations. The chromium silylyne complex reacted with H2 under LED (365 nm) irradiation to reproduce the precursor silylene complex with a (H)Cr=Si(H) moiety, as a result of 1,2-H-H addition across ...
Source: Chemistry - December 13, 2023 Category: Chemistry Authors: Masahiro Matsuoka Koichi Nagata Ryoma Ohno Tsukasa Matsuo Hiromi Tobita Hisako Hashimoto Source Type: research
Regulation of Sulfur Atoms in MoSx by Magneto ‐Electrodeposition for Hydrogen Evolution Reaction
A feasible method is reported to synthesize amorphous MoSx with more active sites under magnetic fields. Owing to the magneto-hydrodynamic effect, the loading mass of MoSx is obviously increased, and the terminal S2 − serving as the active site is enhanced. The MoSx synthesized by electrodeposited under a 5 T magnetic field exhibits excellent hydrogen evolution reaction performance. AbstractCompared with crystalline molybdenum sulfide (MoS2) employed as an efficient hydrogen evolution reaction (HER) catalyst, amorphous MoSx exhibits better activity. To synthesize amorphous MoSx, electrodeposition serving as a convenient ...
Source: Small - December 11, 2023 Category: Nanotechnology Authors: Changdian Li,
Qian Chen,
Ruobing Zheng,
Jie Huan,
Jin Bai,
Lili Zhu,
Yanan Huang,
Xuebin Zhu,
Yuping Sun Tags: Research Article Source Type: research
Elaboration and characterization of molybdenum titanium tungsto-phosphate towards the decontamination of radioactive liquid waste from < sup > 137 < /sup > Cs and < sup > 85 < /sup > Sr
Environ Sci Pollut Res Int. 2023 Dec 8. doi: 10.1007/s11356-023-31104-4. Online ahead of print.ABSTRACTThe crystalline phase of molybdenum titanium tungsto-phosphate (MoTiWPO4) as an inorganic sorbent material was synthesized via the sol-gel method. The physicochemical characteristics of MoTiWPO4 were evaluated by using Fourier transform infrared (FT-IR), scanning electron microscope (SEM), energy dispersive X-ray (EDX), thermal analysis (TGA-DTA), and X-ray diffraction (XRD). MoTiWPO4 sorbent material exhibits a high chemical resistance to HNO3, HCl, and alkaline media. MoTiWPO4 has good thermal stability as it retained a...
Source: Environmental Science and Pollution Research International - December 8, 2023 Category: Environmental Health Authors: Ezzat A Abdel-Galil Abeer E Kasem Sara S Mahrous Source Type: research
Elaboration and characterization of molybdenum titanium tungsto-phosphate towards the decontamination of radioactive liquid waste from < sup > 137 < /sup > Cs and < sup > 85 < /sup > Sr
Environ Sci Pollut Res Int. 2023 Dec 8. doi: 10.1007/s11356-023-31104-4. Online ahead of print.ABSTRACTThe crystalline phase of molybdenum titanium tungsto-phosphate (MoTiWPO4) as an inorganic sorbent material was synthesized via the sol-gel method. The physicochemical characteristics of MoTiWPO4 were evaluated by using Fourier transform infrared (FT-IR), scanning electron microscope (SEM), energy dispersive X-ray (EDX), thermal analysis (TGA-DTA), and X-ray diffraction (XRD). MoTiWPO4 sorbent material exhibits a high chemical resistance to HNO3, HCl, and alkaline media. MoTiWPO4 has good thermal stability as it retained a...
Source: Environmental Science and Pollution Research International - December 8, 2023 Category: Environmental Health Authors: Ezzat A Abdel-Galil Abeer E Kasem Sara S Mahrous Source Type: research
Phase-Regulated Active Hydrogen Behavior on Molybdenum Disulfide for Electrochemical Nitrate-to-Ammonia Conversion
Angew Chem Int Ed Engl. 2023 Dec 7:e202315109. doi: 10.1002/anie.202315109. Online ahead of print.ABSTRACTElectrochemical reduction of nitrate waste is promising for environmental remediation and ammonia preparation. This process includes multiple hydrogenation steps, and thus the active hydrogen behavior on the surface of the catalyst is crucial. The crystal phase refers to the atomic arrangements in crystals that have a great effect on active hydrogen, but the influence of the crystal phase on nitrate reduction is still unclear. Herein, enzyme-mimicking MoS2 in different crystal phases (1T and 2H) are used as models. The...
Source: Angewandte Chemie - December 7, 2023 Category: Chemistry Authors: Yuting Wang Yue Xu Chuanqi Cheng Baoshun Zhang Bin Zhang Yifu Yu Source Type: research
Molybdenum sulphide clusters as redox-active supports for low-valent uranium
Chem. Commun., 2024, Advance Article DOI: 10.1039/D3CC05561B, CommunicationKamaless Patra, William W. Brennessel, Ellen M. Matson The preparation of an actinide substituted cubane cluster,(Cp*3Mo3S4)Cp*UI2, and its reduced derivatives are reported. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chem. Commun. latest articles)
Source: RSC - Chem. Commun. latest articles - December 6, 2023 Category: Chemistry Authors: Kamaless Patra Source Type: research
Molybdenum sulphide clusters as redox-active supports for low-valent uranium
Chem Commun (Camb). 2023 Dec 6. doi: 10.1039/d3cc05561b. Online ahead of print.ABSTRACTThe preparation of an actinide substituted cubane cluster, (Cp*3Mo3S4)Cp*UI2, and its reduced derivatives are reported. Structural and spectroscopic investigations provide insight into the unique interactions between the actinide and its redox-active molybdenum sulphide metalloligand, serving as a model to study atomically-dispersed, low-valent actinide ions on MoS2 surfaces. To probe the ability of the assembly to facilitate multielectron small molecule activation, the reactivity of the fully-reduced cluster, (Cp*3Mo3S4)Cp*U, with azobe...
Source: Chemical Communications - December 6, 2023 Category: Chemistry Authors: Kamaless Patra William W Brennessel Ellen M Matson Source Type: research
Molybdenum sulphide clusters as redox-active supports for low-valent uranium
Chem Commun (Camb). 2023 Dec 6. doi: 10.1039/d3cc05561b. Online ahead of print.ABSTRACTThe preparation of an actinide substituted cubane cluster, (Cp*3Mo3S4)Cp*UI2, and its reduced derivatives are reported. Structural and spectroscopic investigations provide insight into the unique interactions between the actinide and its redox-active molybdenum sulphide metalloligand, serving as a model to study atomically-dispersed, low-valent actinide ions on MoS2 surfaces. To probe the ability of the assembly to facilitate multielectron small molecule activation, the reactivity of the fully-reduced cluster, (Cp*3Mo3S4)Cp*U, with azobe...
Source: Chemical Communications - December 6, 2023 Category: Chemistry Authors: Kamaless Patra William W Brennessel Ellen M Matson Source Type: research
Stable Aluminum Metal Anode Enabled by Dual ‐Functional Molybdenum Nanoparticles
Mo nanoparticles with predominant (110) orientation as catalytic sites endow Mo@NG with strong aluminophilicity and rapid desolvation kinetics, which effectively regulate the homogeneous Al deposition on Mo@NG, exhibiting low voltage hysteresis, reversible Al plating/stripping with high coulombic efficiency, ultralong cycling lifespan, and excellent high-rate capability. AbstractConstructing robust anode with strong aluminophilicity and rapid desolvation kinetics is essential for achieving high utilization, long-term durability, and superior rate performance in Al metal-based energy storage, yet remains largely unexplored....
Source: Small - December 4, 2023 Category: Nanotechnology Authors: Shunlong Ju,
Qing Qiao,
Tian Xu,
Zhongchen Zhao,
Tengfei Zhang,
Guanglin Xia,
Xuebin Yu Tags: Research Article Source Type: research
Molecules, Vol. 28, Pages 7917: Comparative Analysis of Spray-Dried Porcine Plasma and Hydrolyzed Porcine Protein as Animal-Blood-Derived Protein Ingredients for Pet Nutrition
iel
Spray-dried porcine plasma (SDPP) and hydrolyzed porcine protein (HPP) are promising animal protein ingredients sourced from healthy animal blood that are rich in biomolecules, including immunoglobulins, and can be an appropriate and valuable animal protein ingredient to supply the growing need for ingredients that meet the natural needs of carnivorous pets. The aim of this preliminary study was to analyze the chemical composition and mineral profile of a novel HPP compared with results for SDPP. The basic composition analysis followed AOAC guidelines, and the elemental analysis utilized atomic absorption spectrome...
Source: Molecules - December 3, 2023 Category: Chemistry Authors: Katarzyna Kazimierska Wioletta Biel Tags: Article Source Type: research
Serum and urinary essential trace elements in association with major depressive disorders: a case –control study
ConclusionsThe higher levels of I, Se, Cu, and Mo in serum might be protective against the development of MDD, and the excess I and Zn in urine may be associated with MDD pathogenesis. Future research needs to gain a deeper understanding of the metabolic pathways of ETEs, especially I, Se, Zn, Cu, and Mo, in MDD, and their role in the pathogenesis of depression. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - December 1, 2023 Category: Psychiatry Source Type: research
Metabolyc syndrome: A possible food tools to use in primary intervention
Rationale: Nowadays, in the human diet there is a widespread de ficit of different mineral components that influence body healthy development therefore many studies on biofortification (enriching) cultivated plants in various elements are started everywhere in the world. The agro technical method of biofortifying plants with mineral components are considered a s one of the cheapest ways leading to the reduction deficits in the human and animal diet. The effect of iodine and molybdenum salt on basic physiological and biochemical processes in lettuce grown are quite known therefore we evaluated on heathy population, the ...
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: S. Vasto, D. Baldassano, L. Di Rosa, S. Baldassano Source Type: research
