Diagnostic performance of a deep-learning model using 18F-FDG PET/CT for evaluating recurrence after radiation therapy in patients with lung cancer
ConclusionThe 2D slice-based CNN model using18F-FDG PET imaging was able to distinguish well between RT-related changes and tumour recurrence in patients with lung cancer. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - April 8, 2024 Category: Nuclear Medicine Source Type: research
ABO-incompatible Heart Transplantation - evolution of a revolution
In the 1990s, neonates born with severe congenital heart disease faced more than 50% mortality awaiting an ABO-compatible (ABOc) transplant donor. This desperate situation, together with knowledge on gaps of the adaptive immune system in early childhood, led to the clinical exploration of intentional ABO-incompatible (ABOi) heart transplantation. In 2001, West et al. reported the first series of 10 infants in Canada. Since then, consideration of ABOi heart donors has become standard of care for children awaiting transplantation in the first few years of life, resulting in reduced wait times and better organ utilization wit...
Source: The Journal of Heart and Lung Transplantation - April 8, 2024 Category: Transplant Surgery Authors: Neha Bansal, Lori J. West, Jacob Simmonds, Simon Urschel Tags: State of the art Source Type: research
The role of coronary artery disease in lung transplantation: a propensity-matched analysis
ConclusionIn this cohort, relevant CAD was not associated with worse outcomes and should therefore not be considered a contraindication for LuTx. Nonetheless, cardiovascular events in CAD patients highlight the necessity of control of cardiovascular risk factors and a structured cardiac follow-up. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - April 8, 2024 Category: Cardiology Source Type: research
Early Tracheostomy in lung transplantation: Delaying may be the enemy of progress
Ann Thorac Surg. 2024 Apr 5:S0003-4975(24)00255-8. doi: 10.1016/j.athoracsur.2024.03.025. Online ahead of print.NO ABSTRACTPMID:38583513 | DOI:10.1016/j.athoracsur.2024.03.025 (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - April 7, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Paulo Gregorio Christian A Bermudez Source Type: research
Early Tracheostomy in lung transplantation: Delaying may be the enemy of progress
Ann Thorac Surg. 2024 Apr 5:S0003-4975(24)00255-8. doi: 10.1016/j.athoracsur.2024.03.025. Online ahead of print.NO ABSTRACTPMID:38583513 | DOI:10.1016/j.athoracsur.2024.03.025 (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - April 7, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Paulo Gregorio Christian A Bermudez Source Type: research
Early Tracheostomy in lung transplantation: Delaying may be the enemy of progress
Ann Thorac Surg. 2024 Apr 5:S0003-4975(24)00255-8. doi: 10.1016/j.athoracsur.2024.03.025. Online ahead of print.NO ABSTRACTPMID:38583513 | DOI:10.1016/j.athoracsur.2024.03.025 (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - April 7, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Paulo Gregorio Christian A Bermudez Source Type: research
Early Tracheostomy in lung transplantation: Delaying may be the enemy of progress
Ann Thorac Surg. 2024 Apr 5:S0003-4975(24)00255-8. doi: 10.1016/j.athoracsur.2024.03.025. Online ahead of print.NO ABSTRACTPMID:38583513 | DOI:10.1016/j.athoracsur.2024.03.025 (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - April 7, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Paulo Gregorio Christian A Bermudez Source Type: research
Correspondence: serum neutralization of SARS-CoV-2 Omicron sublineages BA.1, BA.2 and BA.5 in lung transplant recipients receiving prophylactic tixagevimab/cilgavimab
(Source: Infection)
Source: Infection - April 7, 2024 Category: Infectious Diseases Source Type: research
Artificial intelligence in lung cancer screening: Detection, classification, prediction, and prognosis
ConclusionsAI offers a promising supportive approach to lung cancer screening, presenting considerable potential in enhancing nodule detection sensitivity, reducing false-positive rates, and classifying nodules. However, the universality and interpretability of AI results need further enhancement. Future research should focus on the large-scale validation of new deep learning-based algorithms and multi-center studies to improve the efficacy of AI in lung cancer screening. (Source: Cancer Medicine)
Source: Cancer Medicine - April 6, 2024 Category: Cancer & Oncology Authors: Wu Quanyang,
Huang Yao,
Wang Sicong,
Qi Linlin,
Zhang Zewei,
Hou Donghui,
Li Hongjia,
Zhao Shijun Tags: REVIEW Source Type: research
Tacrolimus Variability and Clinical Outcomes in the Early Post-lung Transplantation Period: Oral Versus Continuous Intravenous Administration
ConclusionsAdministering tacrolimus orally directly after LuTx leads to a higher variability in blood concentrations compared to intravenous administration. There was no difference in the occurrence of AKI or transplant rejection. (Source: Clinical Pharmacokinetics)
Source: Clinical Pharmacokinetics - April 6, 2024 Category: Drugs & Pharmacology Source Type: research
Recent advances in lung cancer research: unravelling the future of treatment
AbstractLung cancer, a multifaceted disease, demands tailored therapeutic approaches due to its diverse subtypes and stages. This comprehensive review explores the intricate landscape of lung cancer research, delving into recent breakthroughs and their implications for diagnosis, therapy, and prevention. Genomic profiling and biomarker identification have ushered in the era of personalised medicine, enabling targeted therapies that minimise harm to healthy tissues while effectively combating cancer cells. The relationship between pulmonary tuberculosis and lung cancer is examined, shedding light on potential mechanisms lin...
Source: Updates in Surgery - April 6, 2024 Category: Surgery Source Type: research
Tacrolimus Variability and Clinical Outcomes in the Early Post-lung Transplantation Period: Oral Versus Continuous Intravenous Administration
ConclusionsAdministering tacrolimus orally directly after LuTx leads to a higher variability in blood concentrations compared to intravenous administration. There was no difference in the occurrence of AKI or transplant rejection. (Source: Clinical Pharmacokinetics)
Source: Clinical Pharmacokinetics - April 6, 2024 Category: Drugs & Pharmacology Source Type: research
Temporary Mechanical Circulatory Support During Bariatric Surgery: A Novel Bridge to Durable Left Ventricular Assist Device and Cardiac Transplantation
We present three patients with severe obesity and advanced heart failure (HF) who underwent successful bariatric surgery while supported by Impella 5.5 (Abiomed, Inc., Danvers, MA).PMID:38578069 | DOI:10.1177/00031348241244637 (Source: The American Surgeon)
Source: The American Surgeon - April 5, 2024 Category: Surgery Authors: Theo Sher Madison Noom Samer Ganam Joseph Sujka Debbie Rinde-Hoffman Christopher DuCoin Source Type: research
Letermovir prophylaxis for cytomegalovirus in lung-transplant recipients: a comprehensive study with literature review of off-label use and real-world experiences
Clin Exp Med. 2024 Apr 5;24(1):68. doi: 10.1007/s10238-024-01330-2.ABSTRACTLetermovir, initially approved for cytomegalovirus (CMV) prophylaxis in hematopoietic stem-cell transplantation, has gained attention for off-label use in lung-transplant (LTx) recipients. Given the high susceptibility of LTx recipients to CMV infection, this study explores the effectiveness and safety of letermovir prophylaxis. A retrospective analysis of using letermovir for LTx recipients at Tohoku University Hospital (January 2000 to November 2023) was conducted. Case summaries from other Japanese transplant centers and a literature review were ...
Source: Clinical Lung Cancer - April 5, 2024 Category: Cancer & Oncology Authors: Takashi Hirama Yuki Shundo Toshikazu Watanabe Akihiro Ohsumi Tatsuaki Watanabe Yoshinori Okada Source Type: research
