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Pharmaceutical care in respiratory diseases: Current situation and opportunities for Hospital Pharmacy in Spain
CONCLUSIONS: Most centers have pharmacists specialized in respiratory diseases. However, there is room for improvement in terms of sub specialization, participation in multidisciplinary committees, implementation of prioritization criteria, diversification in pathologies treated, as well as greater specific training in this area.PMID:38580504 | DOI:10.1016/j.farma.2024.02.006 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - April 5, 2024 Category: Drugs & Pharmacology Authors: No é Garin Borja Zarate-Tamames Sonia Jornet Eva Mar ía García Mar ía Del Mar López-Gil Gregorio Romero Jorge Del Estal Grupo de trabajo AFANES Source Type: research

Therapeutic management of fibrosis in systemic sclerosis patients - an analysis from the Swiss EUSTAR cohort
CONCLUSION: Overall, in Switzerland, a wide range of medications is prescribed for systemic sclerosis patients. This includes modern, targeted treatments for which randomised controlled clinical trial have been recently reported.PMID:38579324 | DOI:10.57187/s.3630 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Kevin Windirsch Suzana Jordan Mike Oliver Becker Cosimo Bruni Rucsandra Dobrota Muriel Elhai Ion-Alexandru Garaiman Carmen-Marina Mihai Michele Iudici Paul Hasler Camillo Ribi Britta Maurer Armando Gabrielli Anna-Maria Hoffmann-Vold Oliver Distler Source Type: research

Letermovir prophylaxis for cytomegalovirus in lung-transplant recipients: a comprehensive study with literature review of off-label use and real-world experiences
AbstractLetermovir, initially approved for cytomegalovirus (CMV) prophylaxis in hematopoietic stem-cell transplantation, has gained attention for off-label use in lung-transplant (LTx) recipients. Given the high susceptibility of LTx recipients to CMV infection, this study explores the effectiveness and safety of letermovir prophylaxis. A retrospective analysis of using letermovir for LTx recipients at Tohoku University Hospital (January 2000 to November 2023) was conducted. Case summaries from other Japanese transplant centers and a literature review were included. Six cases at Tohoku University Hospital and one at Kyoto ...
Source: Clinical and Experimental Medicine - April 5, 2024 Category: Research Source Type: research

Gut microbiome affects the response to immunotherapy in non ‐small cell lung cancer
ConclusionThe findings of the present study indicated that the diversity of gut microbiota and SCFAs is related to the efficacy of immunotherapy. FMT can effectively delay tumor progression, and enhance the effect of immunotherapy, thus providing evidence for improving the efficacy of immunotherapy in NSCLC patients. (Source: Thoracic Cancer)
Source: Thoracic Cancer - April 4, 2024 Category: Cancer & Oncology Authors: Shengnan Ren, Lingxin Feng, Haoran Liu, Yuke Mao, Zhuang Yu Tags: ORIGINAL ARTICLE Source Type: research

Pulmonary vascular phenotype identified in patients with GDF2 (BMP9) or BMP10 variants: an international multicentre study
Conclusions GDF2 and BMP10 pathogenic variants are rare among PAH patients, and occasionally associated with CHD. HHT cases among GDF2 carriers are limited according to the literature. BMP10 full phenotypic ramifications warrant further investigation. (Source: European Respiratory Journal)
Source: European Respiratory Journal - April 4, 2024 Category: Respiratory Medicine Authors: Grynblat, J., Bogaard, H. J., Eyries, M., Meyrignac, O., Savale, L., Jaïs, X., Ghigna, M.-R., Celant, L., Meijboom, L., Houweling, A. C., Levy, M., Antigny, F., Chaouat, A., Cottin, V., Guignabert, C., Coulet, F., Sitbon, O., Bonnet, D., Humbert, Tags: Pulmonary vascular disease Original Articles: Pulmonary vascular disease Source Type: research

FEV1Q: a race-neutral approach to assessing lung function
Conclusions FEV1Q is an intuitive and simple race-neutral approach to interpreting FEV1 that predicts survival better than current alternative methods. (Source: European Respiratory Journal)
Source: European Respiratory Journal - April 4, 2024 Category: Respiratory Medicine Authors: Balasubramanian, A., Wise, R. A., Stanojevic, S., Miller, M. R., McCormack, M. C. Tags: Lung structure and function Original Articles: Pulmonary function Source Type: research

Incidence, management and prognosis of new-onset sarcoidosis post COVID-19 infection
CONCLUSIONS: Our result suggests there is a potential link between COVID-19 and new-onset sarcoidosis. The potential mechanism for this is through cytokine mediated immune modulation in COVID-19 infection. Obtaining a tissue sample remains key in confirming the diagnosis of sarcoidosis and this may be delayed during active COVID-19 infection.PMID:38567560 | DOI:10.36141/svdld.v41i1.15027 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Oliver Vij Mrinalini Dey Kirsty Morrison Koushan Kouranloo Source Type: research

Incidence, management and prognosis of new-onset sarcoidosis post COVID-19 infection
CONCLUSIONS: Our result suggests there is a potential link between COVID-19 and new-onset sarcoidosis. The potential mechanism for this is through cytokine mediated immune modulation in COVID-19 infection. Obtaining a tissue sample remains key in confirming the diagnosis of sarcoidosis and this may be delayed during active COVID-19 infection.PMID:38567560 | PMC:PMC11008326 | DOI:10.36141/svdld.v41i1.15027 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Oliver Vij Mrinalini Dey Kirsty Morrison Koushan Kouranloo Source Type: research