Evaluation of Hemolysis in One Hundred Sixty Nine Impella 5.5-Supported Patients
Purpose: Hemolysis is understudied in percutaneous LVADs. In the largest series to date, we characterize hemolytic sequelae of Impella 5.5-supported patients. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , L. Lester, S. Kobsa, M. Bojko, N.D. Rajeev, J. Praeger, H.A. Theeuwen, B. Abt, J. Greenberg, J. Nattiv, A. Vaidya, K. Johnston, R. Lee Source Type: research

Assessment of Platelet Response to Aspirin Therapy and Hemocompatibility-Related Adverse Events in HeartMate 3 Left Ventricular Assist Device Recipients
Purpose: Patients receiving left ventricular assist devices (LVADs) typically undergo anticoagulation and aspirin (ASA) therapy. The HeartMate 3 (HM3) has shown promise in reducing hemocompatibility-related adverse events (HRAEs) like stroke, thrombosis and bleeding. However, it remains uncertain whether ASA responsiveness impacts the incidence of HRAEs and if ASA sensitivity changes during HM3 support. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , H. Al Asadi, T. Abart, C. Schwarz, H. Schima, J. Riebandt, C. Marko, D. Wiedemann, B. Messner, D. Zimpfer Source Type: research

Axillary Temporary Mechanical Circulatory Support to Bridge Cardiogenic Shock Patients to Heart Transplantation
We present our experience with axillary artery insertion of TMCS to bridge patients to heart transplantation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , F.A. Napoli, D.A. Baran, M.A. Velez, J.A. Estep, C.A. Sheffield, J.L. Navia, N. Brozzi Source Type: research

Acute Hemodynamic and Echocardiographic Consequences of Surgically-Implanted Axial Flow Pumps in Patients with Cardiogenic Shock
Purpose: Surgically implanted axial-flow temporary left ventricular assist devices (LVADs) are increasingly utilized to support patients with advanced cardiogenic shock. Detailed hemodynamic characterizations following modern device implantation are lacking. We sought to survey the hemodynamic consequences of device implantation in patients supported at our tertiary care heart failure center. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , M. Asher, M. Helmers, N. Weingarten, D. Rekhtman, C. Song, J. DePaolo, M. Shin, A. Brown, J. Wald, M. Cevasco Source Type: research

Durable Left Ventricular Assist Device Implantation in Jehovah ’s Witness Patients
Purpose: Left Ventricular Assist devices are a conventional therapy for patients with end-stage heart failure, but are often not offered to Jehovah ’s Witness patients because of their refusal to receive all blood products. The aim of this study to examine the outcomes of a single-center’s high-volume experience of JW patients undergoing LVAD implantation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , K. Meehan, A. Chinco, C. LaBuhn, K. Moore, J. Okray, N. Wright, V. Hwang, S. Jain, V. Jeevanandam Source Type: research

Utilization of ECMO in Peri-Partum and Post-Partum Patients
Purpose: The rate of pregnancy-related deaths in the United States is rising with cardiovascular disease identified as a leading cause of maternal death and morbidity. Recent data shows existing heart conditions as having the highest estimated relative risk associated with adverse maternal pregnancy outcomes and mortality. Extracorporeal membrane oxygenation (ECMO) is a proven life-saving therapy for patients in cardiogenic shock and respiratory failure. There is little data supporting the use of ECMO in pregnant and recently postpartum women. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , J. Okray, A. Chinco, V. Kagan, C. LaBuhn, K. Meehan, K. Moore, R. Rose, A. Alund, T. Song Source Type: research

Propella: Single-Center Experience and Outcomes
Purpose: The use of peripherally inserted concomitant right and left ventricular support (Propella) has been gaining traction in recent years. Scattered case reports have described the use of Propella or ECPELLA 2.0 as an alternative for biventricular support with reduced rates of limb ischemia observed. Our primary objective is to assess the safety and efficacy of Propella for biventricular support during cardiogenic shock at our institution. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , B. Seadler, W. Andrews, A. Ubert, L. Durham Source Type: research

Short-Term Outcomes of Patients Presented with Cardiogenic Shock and Treated with the Impella 5.x Mechanical Circulatory Support
Purpose: Outcomes of patients presented with cardiogenic shock is associated with very high morbidities and mortality. Extracorporeal life support (ECLS) is the first line mechanical circulatory support (MCS) system for such patients. Recently, the use of Impella 5.x as a MCS has gained more adoption in such patients. We are evaluating early outcomes of patients presenting with cardiogenic shock and supported with the Impella 5.x MCS system. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Dimitriou, S. Jahrkas, I. Balaj, A. Sven, M. Thielmann, A. Koch, N. Pizanis, H. Ali, M. Kamler Source Type: research

Temporary Centrimag BiVAD Support as a Bridge to Heart Transplantation: The Last Decade of Experience at Royal Papworth Hospital
We report our institutional experience with this strategy over the last decade. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , Z. Abdul Aziz, A. Shafi, S. Poon, L. Wang, S. Das De, B. Al-Alao, A. Al-Adhami, K. Wang, C. Lewis, A. Kydd, L. Martinez Marin, S. Bhagra, J. Parameshwar, M. Rafiq, P. Kaul, S. Pettit, M. Berman, D. Jenkins, S. Tsui, H. Smail Source Type: research

Outcomes Comparison of Extracorporeal Membrane Oxygenation Support for Cardiogenic Shock with Acute Decompensated Heart Failure versus Acute Myocardial Infarction
Purpose: Acute decompensated heart failure (ADHF) and acute myocardial infarction (AMI) are etiologies of cardiogenic shock (CS) with distinct pathophysiology that may impact outcomes on VA-ECMO support. The aim of this study is to compare the outcomes of VA-ECMO support between ADHF and AMI. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , Y. Zhao, A. Vinogradsky, T. Powley, A. Lin, Y. Kaku, M. Yuzefpolskaya, P. Colombo, G. Sayer, N. Uriel, J. Fried, K. Takeda Source Type: research

Short-Term Mechanical Circulatory Support Over 65 Years. Is It Worth the Effort?
Purpose: Age has been identified as a risk factor for poor postoperative outcomes some programs have age restrictions when considering short-term MCS initiation.We aim to describe the use of short-term devices in a multicentric cohort. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , F. Sbraga, A. Eixeres, S. Villar, M. Perez Guillen, I. Morales-Rey, L. Garcia Alcalde, E. Perez de la Sota, J. Sarralde Source Type: research

Outcome of Right Ventricular Microaxial Pump Support in Patients Undergoing Cardiac Surgery
Purpose: Right ventricular failure (RVF) after cardiac surgery is associated with an in-hospital mortality rate of up to 75%. Axial flow pumps are one of the options available for the treatment of RVF, however predictors for survival remain unclear due to a dearth published data. We evaluated the clinical outcome of patients treated with right ventricular microaxial flow pump devices (rmAFP) for predictors of mortality and the hemodynamic effects of the pump. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , T. Nils, G.D. Duerr, S. Zimmer, M. Medina, H. Treede Source Type: research

Role of Acquired Von Willebrand Syndrome in the Development of Bleeding Complications in Patients Treated Using Right Ventricular Microaxial Flow Pump Devices: A Retrospective Cohort Study
Purpose: Axial flow pumps are standard treatment in cases of cardiogenic shock and high-risk interventions in cardiology and cardiac surgery, although the optimal anticoagulation strategy remains unclear. We evaluated whether laboratory findings could predict bleeding complications and acquired von Willebrand syndrome (avWS) among patients who were treated using axial flow pumps. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S. Reda, H. R ühl, T. Nils, S. Kreyer, G.D. Duerr, E. Charitos, M. Medina, S. Zimmer, C. Putensen, H. Treede Source Type: research

Relation Between Indexed Surgery and Outcomes in Postcardiotomy Venoarterial Extracorporeal Life Support
This study compared the outcome of VA-ECLS among 4 major cardiovascular procedure. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , Y. Zhao, H. Takayama, A. Vinogradsky, Y. Kaku, M. Yuzefpoksyaka, P.C. Colombo, G. Sayer, N. Uriel, J. Fried, K. Takeda Source Type: research

Midregional-Proadrenomedullin as Biomarker for Heart Failure and Postoperative Outcome After LVAD Implantation
Purpose: Midregional-proAdrenomedullin (MR-proADM) as a biomarker in the context of cardiopulmonary bypass is a relevant marker for heart failure therapy and can predict infections. There is currently no diagnostic marker to highlight early deterioration in the postoperative setting after LVAD implantation. The present study aims to investigate the predictive value of MR-proADM on the postoperative outcome after LVAD in relation to mortality and complications such as right heart failure and infections. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: J. Kremer, , S. Decker, M. Karck, A.L. Meyer Source Type: research