Successful Plasma Exchange to Remove Heparin-Induced-Thrombocytopenia Antibodies Prior to LVAD Implantation: A Case Series
Purpose: Published data on therapeutic plasma exchange (TPE) in patients with heparin induced thrombocytopenia (HIT) prior to left ventricular assist device (LVAD) implantation is limited. Here we describe a case series of patients with acute HIT who underwent TPE prior to LVAD implantation allowing the use of intraoperative heparin. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Ngo-Hamilton, B. Ramu, M. Mazepa, M. Reding, C. Martin, T. Alexy, J. Schultz, V. Maharaj, R. John, A. Shaffer, F. Kamdar, D. Garry, R. Cogswell Source Type: research
Best Practices to Manage Right Ventricular Dysfunction in Patients with Left Ventricular Assist Device Therapy
Purpose: Optimal outcomes in left ventricular assist device (LVAD) therapy recipients require adequate right ventricular (RV) function. However, predicting RV failure remains challenging in many cases, and occasionally, the RV must be supported with mechanical support. RV assist device (RVAD) use adds excess morbidity and mortality. Therefore, strategies to avoid RVAD use in LVAD patients are necessary for optimal outcomes. We have focused on 1) reducing transfusions, 2) tricuspid valve repair, 3) keep mean arterial pressure> 70 mmHg, 4) optimizing pump speed to balance the ventricular septum, 5) inotrope use. (Source: The...
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Brandt, S. Gupta, S. Emani, G. Answini, A. Mehal, C. Bartone, E.S. Chung, G. Egnaczyk Source Type: research
Pre-Implant Right Ventricular Strain Predicts Right Heart Failure After Left Ventricular Assist Device Therapy: A Systematic Review and Meta-Analysis
Purpose: Right heart failure (RHF) is a frequent and serious complication after left ventricular assist device (LVAD) implantation. It affects 10-40% of patients and is a major contributor to morbidity and mortality. Unfortunately, pre-operative predictors for RHF are limited. We aimed to investigate the potential role of pre-implant speckle-tracking derived right ventricular (RV) strain as a predictor of RHF after LVAD implantation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , T. Ngo, D. Huynh, A. Ngo, N. Tran, I. Rajapreyar, J. Rame, E. Chung Source Type: research
Pre-Implant Pulmonary Artery Pulsatility Index and Its Relationship with Early Right Ventricular Failure After Left Ventricular Assist Device Implantation: An INTERMACS Analysis
This study aims to assess the significance of the pre-implant pulmonary artery pulsatility index (PAPI) in predicting right heart failure (RHF) following left ventricular assist device (LVAD) implantation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , T. Ngo, S. Pham, E. Chung, I. Rajapreyar, J. Rame Source Type: research
Outcomes Associated with Protekduo Right Ventricular Assist Device
Purpose: The ProtekDuo (LivaNova, London, UK) is a percutaneous right ventricular assist device (RVAD) that transfers blood from the right atrium to the pulmonary artery, “unloading,” the right ventricle. It is primarily used to treat right ventricular failure. It can be connected to an extracorporeal membrane oxygenation system to provide ventilatory support for failing lungs. There are few studies looking at outcomes associated with ProtekDuo use. We evaluated institutional outcomes associated with ProtekDuo use. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , U. Jorde, D. Goldstein, O. Saeed, S. Vukelic, S. Patel, S. Murthy, M. Uehara, S. Forest, J. Borgi, D. Sims Source Type: research
Novel Machine Learning Algorithms for Predicting Early Right Heart Failure Post Left Ventricular Assist Device Implantation: An Analysis from Theeuromacs Registry
Purpose: Right-sided heart failure (RHF) post left ventricular device implantation (LVAD) is still a major complication associated with significant morbidity and mortality. The current risk scores for early RHF prediction have limitations besides that the contemporary LVAD devices are not represented in most of the studies. We sought to explore the use of machine-learning algorithms to create a risk score for early RHF post-contemporary LVAD implantations. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: M. Abdelshafy, O. Soliman, A. Simpkin, K. Veen, A. Elkoumy, H. Elzomor, T. De By, B. Logstrup, A. Loforte, F. Schoenrath, E. Potapov, L. Paluszkiewicz, J. Gummert, P. Mohacsi, B. Meyns, Source Type: research
Left Ventricular Assist Device Recipients with a History of Cardiovascular Disease or Cardiothoracic Surgery Have Increased Mortality
Purpose: Right ventricular failure (RVF) is a major complication following left ventricular assist device (LVAD) placement and can significantly increase mortality. The identification of preoperative risk factors could help delineate the risk for RVF in LVAD recipients. While early RVF is well established, the risk factors for late RVF remain are not well established. Our goal was to evaluate the prevalence of late RVF in LVAD patients with a history of coronary artery disease (CAD) and prior cardiac surgery (coronary artery bypass grafting [CABG] or percutaneous coronary intervention). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S.S. Scott, S. Smith Source Type: research
Right Heart Reserve Function Assessed with Fluid Loading Test Predicts Late Right Heart Failure in Patients Undergoing Left Ventricular Assist Device Implantation
Purpose: A left ventricular assist device (LVAD) is an effective therapeutic option for advanced heart failure. Late right heart failure (LRHF) is a complication after LVAD implantation associated with increasing morbidity and mortality; however, the assessment of right heart function, including right heart reserve function after LVAD implantation, has not been established. We focused on a fluid loading test with right heart catheterization (RHC) to evaluate right heart pre-load reserve function and investigate its impact on LRHF. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , T. Kurihara, Y. Isotani, C. Bujo, J. Ishida, E. Amiya, M. Hatano, M. Kimura, S. Shimada, M. Ando, M. Ono, I. Komuro Source Type: research
Racial Disparities in Clinical Characteristics and Outcomes of LVAD Implantation: A Comparative Analysis Between Black and White Patients
Purpose: We aimed to investigate disparities in clinical characteristics and/or clinical outcomes in patients who underwent implantation of a Left Ventricular Assist Device (LVAD) at our center, a safety net hospital, among those who self-identified as either Black or African American and White. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: Jr. P. O. Diaz, , R. Severdija, U. Hooda, Y. Natori, J. Simkins, J.M. Hare, J. Bauerlein, H. Butrous, A. Phancao, S. Anjan, M. Munagala Source Type: research
Ethnic Disparities in Clinical Characteristics and Outcomes of LVAD Implantation: A Comparative Analysis Between Hispanic and Non-Hispanic Patients
Purpose: Our study aims to investigate disparities in characteristics and clinical outcomes among Hispanic patients who underwent Left Ventricular Assist Device (LVAD) implantation compared to non-Hispanic patients at our center. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , , R. Severdija, U. Hooda, Y. Natori, J. Simkins, J.M. Hare, J. Bauerlein, H. Butrous, A. Phancao, S. Anjan, M. Munagala Source Type: research
Gender Trends of Left Ventricular Assist Device Insertion in Australia
Purpose: Left ventricular assist device (LVAD) are a life-saving intervention for advanced heart failure. With an ongoing mismatch between organ donors and recipients, LVAD utilisation is increasing. Australian epidemiological data regarding LVAD recipient demographics aids long term clinical decision making. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , L. Nedkoff, N. Bart Source Type: research
Recurrent CardioMEMS Device-Related Infection Post Heart Transplant
Introduction: CardioMEMS (CM) infection is a rare complication. Transcatheter retrieval after CM infection has been previously reported once which had resulted in the patient ’s death. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: A. Aijaz, Y.A. Wahid, , J. Gorthi Source Type: research
Reactivation of Chagas Disease
Introduction: Reactivation of Chagas disease is described in immunossupressed patients, such as post-transplant, and may manifest under different clinical presentation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , M. Heringer, G. Campos, L. Xavier, S. Mangini, F. Bacal Source Type: research
Eosinophilic Myocarditis After Heart Transplantation
We present a case of a patient with eosinophilic myocarditis after heart transplantation progressing to cardiogenic shock. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , G. Campos, S. Moraes, S. Mangini, X. Jos é Leudo, A. Barbara, F. Bacal Source Type: research
Orthotopic Heart Transplantation Complicated by Chylopericardium: Management and Intervention
Introduction: Chylopericardium, an uncommon complication of orthotopic heart transplant (OHT), is defined by the pericardial sac's accumulation of lymph and emulsified fats, presenting a distinctive milky appearance and heightened triglyceride concentrations. Untreated continuous chyle leakage can adversely influence the patient's nutritional state, metabolic balance, and immunological responses. In this case report, we highlight a unique presentation and management of chylopericardium post-OHT. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: A. Challa, H. Valand, , K. Felpel, A. Haleem, L. Lagazzi, J. Mehaffey, A. Toker, M. Caccamo, G. Sokos, C. Bianco Source Type: research
