Does Ex Vivo Lung Perfusion Mitigate the Detrimental Effects of Primary Graft Dysfunction? A Propensity Matched Analysis of the United Network for Organ Sharing Database
Purpose: Previous studies and anecdotal reports have proposed that recipients who develop primary graft dysfunction grade 3 (PGD3) following lung transplantation from allografts that underwent ex vivo lung perfusion (EVLP) have improved outcomes, as compared to those who did not undergo EVLP. We sought to determine if this held true in a national database. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , E.Y. Cui, D. Satija, M.C. Henn, C.T. Walk, K. Choi, V. Ramsammy, N.A. Mokadam, A.M. Ganapathi, B.A. Whitson Source Type: research
Prevalence, Risk Factors and Prognosis of Bronchial Dehiscence After Lung Transplantation. A 10 Years Single Center Study
Purpose: Bronchial ischemia is common after lung transplantation (LT) and may lead to airway complications such as dehiscence (DH). However, few studies assess its incidence using MDS and/or ISHLT classifications (1). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: M. Spaes, C. Landais, F. Gonin, T. Ngo, D. Usturoi, M. Glorion, J. De Wolf, C. Pricopi, F. Parquin, E. Cuquemelle, O. Brugiere, A. Vallee, J. Messika, A. Roux, E. Sage, Source Type: research
Intraoperative Factors Associated with Acute Kidney Injury Following Lung Transplant
We examined a number of intraoperative factors, including prolonged hypotension, prolonged acidemia, administration of blood products, and use of intraoperative mechanical support, to determine if these were risk factors for postoperative acute kidney injury (AKI). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , , S. Miller, E. Sako, N. Das, L. Jones, H. Keyt Source Type: research
Factors Associated with Long-Term Survival in Lung Transplant Recipients Age =70 Years
Purpose: Recipients ≥70 years make up an increasing proportion of total lung transplant recipients but continue to face worse post-transplant outcomes compared to younger recipients. We investigated factors associated with long-term survival in this population. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , B.L. Shou, J.M. Ruck, A.F. Akbar, A. Kalra, A.J. Casillan, J.S. Ha, E.L. Bush, C.A. Merlo Source Type: research
Impact of Perioperative Gabapentinoid Use on Lung Transplant Outcomes
Purpose: In a recent meta-analysis, perioperative gabapentinoid use was associated with greater risk of adverse events in surgical patients. However, it remains unclear how perioperative gabapentinoid use affects lung transplant outcomes. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , J.M. Ruck, E.L. Larson, A. Akbar, A.J. Casillan, J.S. Ha, A.B. Massie, D.L. Segev, C.A. Merlo, E.L. Bush Source Type: research
Eighteen-Year Single Center Experience with Lung Transplantation in Pediatric Patients Younger Than 12 Years Old
In this study, we present our 18-year experience with lung transplantation in pediatric patients younger than 12 years old. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: D. Bobylev, J. Carlens, N.D. De Manna, K. Aburahma, C. Mueller, A. Saipbaev, M. Greer, A. Horke, C. Kuehn, M. Avsar, A. Weymann, A. Ruhparwar, N. Schwerk, J. Salman, Source Type: research
Outcome of COVID-19 Positive Donor Lung Transplantation
The objective of this study is to characterize the short-term outcomes of lung transplants from COVID-19-positive donors in the United States. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S.T. Kim, P.T. Gaynor, D. Sayah, A. Ardehali Source Type: research
Does Donor-Recipient Age Mismatch Impact the Recipient's Survival in Lung Transplantation?
Purpose: The impact of age mismatch between donors and recipients for lung transplantation has not been clarified. The purpose of this study is to determine the survival outcomes of recipients of aged-mismatched donor lungs. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S.T. Kim, Z. Shameem, C.C. Le, S. Lee, A. Ardehali Source Type: research
Lung Transplantation for COVID-19 Lung Failure: Does Bridging with ECMO Impact Outcomes?
Purpose: There has been an increasing number of patients with COVID-19 lung failure requiring ECMO as a bridge to lung transplantation. The purpose of this report is to characterize the outcomes of ECMO as bridge-to-lung transplantation among COVID-19 lung failure patients. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S.T. Kim, R. Biniwale, D. Sayah, A. Ardehali Source Type: research
Are Highly Sensitized Recipients at Increased Risk for Early or Late Graft Dysfunction After Lung Transplantation?
Purpose: Investigate the association between of pre-transplant higher panel reactive antibody (PRA) and occurrence of high-grade primary graft dysfunction (PGD) after lung transplant (LTx) as well as impact on late outcomes in a contemporary cohort at a high-volume center. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , K. Bauza, L. Thuita, W. Tsuang, M. Budev, J. Yun, K. McCurry Source Type: research
Time-Dependent Lung Transplant Survival Assessment After Previous Coronary Revascularization
This study focuses on the length of time between prior coronary intervention and lung transplant. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: R. May, M. Azuma, , Y. Toyoda, N. Shigemura, A. Mishkin Source Type: research
Ex Vivo Lung Perfusion is Effective in Lung Transplantation: A Multi-Center Registry Data Study
In this study, we compared LTx outcomes by EVLP utilization stratified by DCD and donation after brain death (DBD). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , G. Loor, M. Hartwig, D. Van Raemdonck, M. Villavicencio, F. Ius, K. Ghadimi, J. Salman, S. Chandrashekaran, T. Machuca, P.G. Sanchez, K. Subramaniam, A. Neyrinck, H. Calvelli, M. Warnick, H. Zhao, S. Huddleston, A. Osho, E. D'Silva, U. Ramamurthy, A. Le Source Type: research
A Single-Center Analysis of Lung Transplantation Outcomes Comparing Donation After Circulatory Death and Donation After Brain Death
Purpose: While the majority of lung transplants (LTx) are from donation after brain death (DBD), donation after circulatory death (DCD) has emerged as a strategy to increase the donor organ pool. There is significant variability in DCD utilization across geographic regions and individual centers in the United States, yet the majority of studies on DCD LTx analyze national transplant registry data that may not reflect these differences. We performed a single-center study comparing outcomes for DCD and DBD LTx. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , H. Calvelli, M. Azuma, H. Zhao, Y. Toyoda Source Type: research
Risk Factors of Inhaled Tobramycin Related Nephrotoxicity Post Lung Transplantation
Purpose: Tobramycin inhaled solution (ITS) is considered to have minimal systemic aminoglycoside, toxicity; however, there have been reports of nephrotoxicity. Lung transplant recipients (LTxr) may be at a higher risk for ITS nephrotoxicity due to CKD, calcineurin inhibitors, and having a higher rate of systemic ITS absorption due to less mucus production and a less acidic pH within the lungs. Our study aims to investigate the association between ITS, renal function, and survival in LTxr. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: M. Azuma, , A. Gillespie, A. He, H. Kehara, N. Shigemura, Y. Toyoda, I. Rakhman Source Type: research
Mortality in Single vs Double Lung Retransplant
Purpose: We investigated whether single or double Re-Ltx along with laterality of lung transplantation yielded better survival outcomes. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: O. Follis, , H. Kehara, R. Yanagida, K. Krishan, E. Leotta, N. Shigemura, Y. Toyoda Source Type: research
