Brain-Computer Interface With Language Model-Electroencephalography Fusion for Locked-In Syndrome
Conclusions. Individuals who have incomplete LIS may benefit from an EEG-based BCI system, which relies on EEG classification and a statistical language model. Steps to further improve the system are discussed. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - April 14, 2014 Category: Neurology Authors: Oken, B. S., Orhan, U., Roark, B., Erdogmus, D., Fowler, A., Mooney, A., Peters, B., Miller, M., Fried-Oken, M. B. Tags: Clinical Research Articles Source Type: research
Comparison of the Checkerboard P300 Speller vs. the Row-Column Speller in Normal Elderly and an Aphasic Stroke Population (S21.006)
CONCLUSION: Our study demonstrates that stroke patients with Broca’s aphasia can use a P300 visual speller to communicate. Our results also indicate that in the elderly population, CBP is a superior paradigm compared to RCP. Disclosure: Dr. Shih has received research support from Eisai Inc., and Visualase Inc. Dr. Townsend has nothing to disclose. Dr. Krusienski has nothing to disclose. Dr. Shih has nothing to disclose. Dr. Shih has nothing to disclose. Dr. Heggeli has nothing to disclose. Dr. Paris has nothing to disclose. Dr. Meschia has nothing to disclose. (Source: Neurology)
Source: Neurology - April 9, 2014 Category: Neurology Authors: Shih, J., Townsend, G., Krusienski, D., Shih, K., Shih, R., Heggeli, K., Paris, T., Meschia, J. Tags: Neuro-rehabilitation and Neural Repair Source Type: research
“Answering with the Eyes”: Challenges in Communication About the End of Life in Patients with Locked-In Syndrome (FR404)
Describe the clinical entity of locked-in-syndrome, including the physical, emotional, and spiritual symptoms that accompany this unique syndrome. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - February 1, 2014 Category: Palliative Care Authors: Joshua Jones, Michael Worley, Anthony Bianco, Matt Mendlik, Irene Yeh Source Type: research
A Vibrotactile P300-Based Brain-Computer Interface for Consciousness Detection and Communication.
Abstract
Brain-computer interface (BCI) has been used for many years for communication in severely disabled patients. BCI based on electrophysiological signals has enabled communication, using auditory or visual stimuli to elicit event-related potentials (ERPs). The aim of this study was to determine whether patients with locked-in syndrome (LIS) could elicit a P300 wave, using a vibrotactile oddball paradigm for establishing somatosensory BCI-based communication. Six chronic LIS patients performed 2 electroencephalography (EEG)-based vibrotactile P300 oddball tasks. After a simple mental counting task of ...
Source: Clinical EEG and Neuroscience - January 10, 2014 Category: Neuroscience Authors: Lugo ZR, Rodriguez J, Lechner A, Ortner R, Gantner IS, Laureys S, Noirhomme Q, Guger C Tags: Clin EEG Neurosci Source Type: research
Quantifying Cortical EEG Responses to TMS in (Un)consciousness.
Abstract
We normally assess another individual's level of consciousness based on her or his ability to interact with the surrounding environment and communicate. Usually, if we observe purposeful behavior, appropriate responses to sensory inputs, and, above all, appropriate answers to questions, we can be reasonably sure that the person is conscious. However, we know that consciousness can be entirely within the brain, even in the absence of any interaction with the external world; this happens almost every night, while we dream. Yet, to this day, we lack an objective, dependable measure of the level of co...
Source: Clinical EEG and Neuroscience - January 8, 2014 Category: Neuroscience Authors: Sarasso S, Rosanova M, Casali AG, Casarotto S, Fecchio M, Boly M, Gosseries O, Tononi G, Laureys S, Massimini M Tags: Clin EEG Neurosci Source Type: research
A novel spelling system for locked-in syndrome patients using only eye contact.
Conclusion: This new grid is a valuable communication tool, especially in situations, such as bathing, getting dressed or out of house activities where no devices are available. Implications for Rehabilitation Communication with patients with locked-in syndrome is a complicated and strenuous task. Communication methods, such as the alphabet board and brain-computer interfaces, are time consuming or too sophisticated to use in daily life tasks. This communication grid is fast, easy to use and memorise and requires only vertical eye movement.
PMID: 24328459 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - December 16, 2013 Category: Rehabilitation Authors: Kopsky DJ, Winninghoff Y, Winninghoff AC, Stolwijk-Swüste JM Tags: Disabil Rehabil Source Type: research
Evaluation of Quality of Life in Complete Locked-In Syndrome Patients
Journal of Palliative Medicine Nov 2013, Vol. 16, No. 11: 1455-1458. (Source: Journal of Palliative Medicine)
Source: Journal of Palliative Medicine - November 11, 2013 Category: Palliative Care Tags: article Source Type: research
Listen up: new tool to help people who are locked in
Paralysed people with locked-in syndrome, who can't control any part of their body may soon be able to communicate just by listening to voices (Source: New Scientist - Health)
Source: New Scientist - Health - November 9, 2013 Category: Consumer Health News Source Type: research
Electroencephalographic profiles for differentiation of disorders of consciousness
Conclusions:
Proposed EEG profiles offer user-independent, repeatable, comprehensive and continuous representation of relevant EEG characteristics, intended as an aid in differentiation between VS/UWS and MCS states and diagnostic prognosis. To enable further development of this methodology into clinically usable tests, we share user-friendly software for MP decomposition of EEG (http://braintech.pl/svarog) and scripts used for creation of the presented profiles (attached to this article). (Source: BioMedical Engineering OnLine)
Source: BioMedical Engineering OnLine - October 21, 2013 Category: Biomedical Engineering Authors: Urszula MalinowskaCamille ChatelleMarie-Aurélie BrunoQuentin NoirhommeSteven LaureysPiotr Durka Source Type: research
A case of neuromyelitis optica with locked-in syndrome
We report a case of a 40 years old male who presented with ascending weakness and sphincter involvement. While in hospital, he became quadriplegic and developed bifacial weakness and frozen eyes. He was fully conscious and was obeying commands by blinking. MR scan showed diffuse hyperintense T2 signal change from the mid brain up to the conus medullaris. Lumbar puncture showed pleocytosis with low glucose ratio. Oligoclonal bands were absent. Infectious screen was negative. Serum aquaporin 4 antibodies were positive. Patient showed a significant response to a course of plasma exchange and steroids. He was subsequently star...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Sharaf, N., Gosal, D. Tags: Immunology (including allergy), Cranial nerves, Multiple sclerosis, Ophthalmology Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research
A clinical screening protocol for the RSVP Keyboard brain-computer interface.
Conclusions: The RSVP BCI screening protocol is a brief, repeatable technique for patients with different levels of LIS to identify the presence/absence of skills for BCI use. Widespread adoption of screening methods should be a clinical goal and will help standardize BCI implementation for research and intervention. Implications for Rehabilitation People with locked-in syndrome must have certain sensory, motor, cognitive and communication skills to successfully use a brain-computer interface (BCI) for communication. A screening profile would be useful in identifying potentially suitable candidates for BCI.
PMID: 2...
Source: Disability and Rehabilitation. Assistive Technology. - September 23, 2013 Category: Rehabilitation Authors: Fried-Oken M, Mooney A, Peters B, Oken B Tags: Disabil Rehabil Assist Technol Source Type: research
Fragmentation of Slow Wave Sleep after Onset of Complete Locked-In State
Locked-in syndrome (LIS) as a result of brainstem lesions or progressive neurodegenerative disorders, such as amyotrophic lateral sclerosis (ALS), is a severe medical condition in which a person is fully conscious but unable to move or talk. LIS can transition into complete locked-in syndrome (CLIS) in which residual abilities to communicate through muscle twitches are entirely lost. It is unknown how CLIS affects circadian rhythm and sleep/wake patterns. Here we report a 39-year-old ALS patient who transitioned from LIS to CLIS while brain activity was continuously recorded using electrocorticography (ECoG) over one month...
Source: Journal of Clinical Sleep Medicine : JCSM - September 14, 2013 Category: Sleep Medicine Source Type: research
Is tracheostomy still an option in amyotrophic lateral sclerosis? Reflections of a multidisciplinary work group.
CONCLUSIONS: Current practice in Switzerland and France tends to discourage the use of TPPV in ALS. Fear of a "locked-in syndrome", the high burden placed on caregivers, and unmasking cognitive disorders occurring in the evolution of ALS are some of the caveats when considering TPPV. Most decisions about TPPV are taken in emergency situations in the absence of advance directives. One exception is that of young motivated patients with predominantly bulbar disease who "fail" NIV.
PMID: 23925784 [PubMed - in process] (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - August 14, 2013 Category: Journals (General) Authors: Heritier-Barras AC, Adler D, Iancu Ferfoglia R, Ricou B, Gasche Y, Leuchter I, Hurst S, Escher-Imhof M, Pollak P, Janssens JP Tags: Swiss Med Wkly Source Type: research
Pupil responses allow communication in locked-in syndrome patients.
We report here that pupil size measured by a bedside camera can be used to communicate with patients with locked-in syndrome. With the same protocol we demonstrate command-following for a patient in a minimally conscious state, suggesting its potential as a diagnostic tool for patients whose state of consciousness is in question. Importantly, neither training nor individual adjustment of our system's decoding parameters were required for successful decoding of patients' responses.
PMID: 23928079 [PubMed - in process] (Source: Current Biology)
Source: Current Biology - August 5, 2013 Category: Biology Authors: Stoll J, Chatelle C, Carter O, Koch C, Laureys S, Einhäuser W Tags: Curr Biol Source Type: research
Locked-in Syndrome as a Presentation of Snakebite.
We present four children that had LIS; three patients had total and one had incomplete LIS. All patients made successful recovery with polyvalent anti-snake venom and supportive management. This case series highlights the importance of early diagnosis of LIS in snake bite.
PMID: 23942434 [PubMed - in process] (Source: Indian Pediatrics)
Source: Indian Pediatrics - July 8, 2013 Category: Pediatrics Authors: Azad C, Mahajan V, Jat KR Tags: Indian Pediatr Source Type: research
