The locked-in syndrome: posterior stroke in the ED
We present this report and brief review as it is unusual to watch locked-in syndrome evolve in the ED. Providers should be aware of the presenting symptoms and the differential diagnosis for bulbar muscle weakness as well as the management of posterior stroke. (Source: The American Journal of Emergency Medicine)
Source: The American Journal of Emergency Medicine - May 22, 2013 Category: Emergency Medicine Authors: Corey Goldberg, Stephen Topp, Christopher Hopkins Tags: Case Reports Source Type: research

Locked-In Syndrome as a Result of Cyclizine Administration
Movement disorders, including akathisia, dystonia, and tardive dyskinesia, resulting from the use of antiemetic medications are not uncommon side effects in the palliative care setting. There have been a number of case reports of severe acute dystonic reactions after single doses of cyclizine and of transient paralysis also after single doses of cyclizine. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 8, 2013 Category: Palliative Care Authors: Philip Lee Tags: Letters Source Type: research

Two different manifestations of locked-in syndrome.
Abstract Locked-in syndrome (LIS) is an entity that usually occur a consequence of the lesion of ventral part of pons. Etiology of locked-in syndrome can be vascular and nonvascular origin. Locked-in syndrome usually occurs as a consequence of thrombosis of intermedial segment of basilar artery that induces bilateral infarction of the ventrobasal part of the pons. Additionally, LIS can be caused by trauma which often leads to posttraumatic thrombosis of basilar artery. The incidence of locked-in syndrome is still unknown. The basic clinical features of locked-in syndrome are: quadriplegia (a consequence of...
Source: Collegium Antropologicum - March 1, 2013 Category: Epidemiology Authors: Golubović V, Muhvić D, Golubović S, Juretić M, Tokmadzić VS Tags: Coll Antropol Source Type: research

Finding the key: acute locked-in syndrome treated with interventional neuroradiology.
PMID: 23373504 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - February 4, 2013 Category: Journals (General) Authors: Stuart G Tags: Med J Aust Source Type: research

Clinical Characteristics and Outcome in the Acute Phase of Ischemic Locked-In Syndrome: Case Series of Twenty Patients with Ischemic LIS
Eur Neurol 2013;69:207–212 (DOI:10.1159/000345272) (Source: European Neurology)
Source: European Neurology - January 9, 2013 Category: Neurology Source Type: research

EEG in connection with coma.
Abstract BACKGROUND Coma is a dynamic condition that may have various causes. Important changes may take place rapidly, often with consequences for treatment. The purpose of this article is to provide a brief overview of EEG patterns in comas with various causes, and indicate how EEG contributes in an assessment of the prognosis for coma patients.METHOD The article is based on many years of clinical and research-based experience of EEG used for patients in coma. A self-built reference database was supplemented by searches for relevant articles in PubMed.RESULTS EEG reveals immediate changes in coma, and ca...
Source: Tidsskrift for den Norske Laegeforening - January 8, 2013 Category: Journals (General) Authors: Wilson JA, Nordal HJ Tags: Tidsskr Nor Laegeforen Source Type: research