Visuo-motor integration in unresponsive wakefulness syndrome: A piece of the puzzle towards consciousness detection?
CONCLUSIONS: Our protocol could be a promising approach to potentiate the functional connectivity within large-scale visuomotor networks, thus allowing identifying the patients suffering from a functional locked-in syndrome (i.e. individuals showing an extreme behavioral motor dysfunction although with somehow preserved cognitive functions that can be identified only through para-clinical tests) within individuals with UWS.
PMID: 26409404 [PubMed - in process] (Source: Restorative Neurology and Neuroscience)
Source: Restorative Neurology and Neuroscience - January 25, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research
Locked-In Syndrome: Case Report and Discussion of Decisional Capacity
Locked-in syndrome (LIS) is a rare neurologic disorder rendering an individual quadriplegic and anarthric with preserved self-awareness and normal if not near-normal cognition. A lesion to the ventral pons causes the classic form of LIS, and patients can typically interact with their environment with eye/eyelid movements. LIS patients may live for years with preserved quality of life (QoL) and cognitive function, but with severe disability. However, medical providers and family often underestimate the patient’s QoL, and choose less aggressive care. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - December 7, 2015 Category: Palliative Care Authors: Samuel Maiser, Ashish Kabir, David Sabsevitz, Wendy Peltier Source Type: research
A brain-computer interface to support functional recovery.
Authors: Kjaer TW, Sørensen HB
Abstract
Brain-computer interfaces (BCI) register changes in brain activity and utilize this to control computers. The most widely used method is based on registration of electrical signals from the cerebral cortex using extracranially placed electrodes also called electroencephalography (EEG). The features extracted from the EEG may, besides controlling the computer, also be fed back to the patient for instance as visual input. This facilitates a learning process. BCI allow us to utilize brain activity in the rehabilitation of patients after stroke. The activity of the cere...
Source: Frontiers of Neurology and Neuroscience - December 2, 2015 Category: Neuroscience Tags: Front Neurol Neurosci Source Type: research
Learning from brain control: clinical application of brain –computer interfaces
In conclusion, clinical application of brain machine interfaces in well-defined and circumscribed neurological disorders have demonstrated surprisingly positive effects. The application of BCIs to psychiatric and clinical–psychological problems, however, at present did not result in substantial improvement of complex behavioral disord ers. (Source: e-Neuroforum)
Source: e-Neuroforum - November 1, 2015 Category: Neuroscience Source Type: research
Learning from brain control: clinical application of brain –computer interfaces
In conclusion, clinical application of brain machine interfaces in well-defined and circumscribed neurological disorders have demonstrated surprisingly positive effects. The application of BCIs to psychiatric and clinical–psychological problems, however, at present did not result in substantial improvement of complex behavioral disord ers. < /p > (Source: e-Neuroforum)
Source: e-Neuroforum - October 31, 2015 Category: Neuroscience Source Type: research
Learning from brain control: clinical application of brain–computer interfaces
In conclusion, clinical application of brain machine interfaces in well-defined and circumscribed neurological disorders have demonstrated surprisingly positive effects. The application of BCIs to psychiatric and clinical–psychological problems, however, at present did not result in substantial improvement of complex behavioral disorders. (Source: e-Neuroforum)
Source: e-Neuroforum - October 6, 2015 Category: Neuroscience Source Type: research
Poster 120 Recovery of Function after Locked-In Syndrome: A Case Report
A. D. Weidenhammer: I Have No Relevant Financial Relationships To Disclose. (Source: PM and R)
Source: PM and R - September 1, 2015 Category: Rehabilitation Authors: Adam D. Weidenhammer, Michael Marino Source Type: research
Quality of life in patients with locked-in syndrome: Evolution over a 6-year period
DiscussionIn opposition to a widespread opinion, LIS persons report a relatively satisfactory QoL level that stays stable over time, suggesting that life with LIS is worth living. Preservation of autonomy and communication may help them to live as normal life as possible. (Source: Orphanet Journal of Rare Diseases)
Source: Orphanet Journal of Rare Diseases - July 19, 2015 Category: Internal Medicine Authors: Marie-Christine RousseauKarine BaumstarckMarine AlessandriniVéronique BlandinThierry Billette de VillemeurPascal Auquier Source Type: research
Traumatic atlanto-occipital dissociation presenting as locked-in syndrome
We present an unusual presentation of unstable atlanto-occipital dissociation as locked-in syndrome. Traumatic atlanto-occipital dissociation is a severe injury that accounts for 15–20% of all fatal cervical spinal injuries. A disruption occurs between the tectorial ligaments connecting the occipital condyle to the superior articulating facets of the atlas, resulting in anterior, longitudinal, or posterior translation, and it may be associated with Type III odontoid fractures. Furthermore, the dissociation may be complete (atlanto-occipital dislocation) or incomplete (atlanto-occipital subluxation), with neurologic findi...
Source: Journal of Clinical Neuroscience - July 17, 2015 Category: Neuroscience Source Type: research
Beyond the gaze: Communicating in chronic locked-in syndrome
Brain Injury, Ahead of Print. (Source: Brain Injury)
Source: Brain Injury - July 16, 2015 Category: Neurology Tags: article Source Type: research
Recovery From Locked-in Syndrome
This case report describes a 22-year-old man who presented with an acute basilar artery occlusion. (Source: JAMA Neurology)
Source: JAMA Neurology - July 1, 2015 Category: Neurology Source Type: research
Man with locked-in syndrome challenges GMC ruling on doctors’ involvement in ending his life
(Source: BMJ News)
Source: BMJ News - June 29, 2015 Category: Journals (General) Source Type: research
Neural Point-and-Click Communication by a Person With Incomplete Locked-In Syndrome
This study demonstrates the first use of an intracortical brain–computer interface for neural point-and-click communication by an individual with incomplete locked-in syndrome. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: Bacher, D., Jarosiewicz, B., Masse, N. Y., Stavisky, S. D., Simeral, J. D., Newell, K., Oakley, E. M., Cash, S. S., Friehs, G., Hochberg, L. R. Tags: Clinical Research Articles Source Type: research
An Inquiry of Brain Computer Interfaces for Home Usage (P4.178)
CONCLUSIONS: Based on both our results and the literature we believe that Epoc mainly employs potentials from facial muscle contraction. However, it is a promising technology for future research with possible uses not only with patients with ALS and ILS but also in applications such as video games for healthy subjects. Study Supported by:Disclosure: Dr. Avramidis has nothing to disclose. Dr. Palosaari Eladhari has nothing to disclose. Dr. Avramidis has nothing to disclose. (Source: Neurology)
Source: Neurology - April 8, 2015 Category: Neurology Authors: Avramidis, S., Palosaari Eladhari, M., Avramidis, T. Tags: Neurodiagnosis and Health Outcomes Source Type: research
"Reverse Locked-in Syndrome": A rare presentation after endovascular recanalization of top-of-the-basilar artery occlusion (P4.302)
CONCLUSION: Complete opthalmoplegia, bilateral ptosis, and arreactive mydriasis without appendicular motor dysfunction, a "reverse locked-in" state, is a rare presentation after ischemic stroke involving the paramedian midbrain tegmentum. This syndrome is the opposite of locked-in syndrome, which is cause by ventral pontine infarction. Timely endovascular thrombectomy, even when a patient presents in coma, may offer dramatic recovery with good functional outcome.Disclosure: Dr. Raibagkar has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Kaplan has nothing to disclose. Dr. Chavali has nothing to disclose. Dr. N...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Raibagkar, P., Kim, J., Kaplan, T., Chavali, R., Nitka, M., Chou, S., Edlow, B. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Interventional Treatment for Ischemic Stroke Source Type: research
