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Cognitive profiles of older adults with a prior traumatic brain injury versus healthy controls: A meta-analysis.
CONCLUSIONS: TBI in older adults leads to moderate deficits on all measured cognitive abilities, with the largest effects observed in naming and vocabulary abilities. The findings pertain broadly to TBI of mixed injury severities and times post-injury, although the majority of participants sustained TBIs of mild uncomplicated severity within one-year post-injury. Future research must address methodological limitations such as variability in reporting injury information, inconsistency in defining older age, and lack of orthopaedic comparison groups in order to permit more nuanced conclusions for this population. PMID: 2...
Source: Brain Injury - April 22, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Corrigendum.
Authors: PMID: 29672180 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - April 20, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Living and ageing with stroke: an exploration of conditions influencing participation in social and leisure activities over 15 years.
CONCLUSIONS: Long-term participation after stroke is possible despite impairments, but is influenced by a range of personal and environmental conditions. Stroke rehabilitation should be based on an awareness of this influence and address conditions that change with time and ageing during different phases after stroke. PMID: 29672185 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - April 20, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Time use and physical activity in a specialised brain injury rehabilitation unit: an observational study.
CONCLUSION: Similar to stroke units, inpatients in a specialised brain injury unit spend large parts of the day sedentary, alone and doing non-therapeutic activities. Strategies need to be evaluated to address this problem, particularly for people with greater physical dependence. PMID: 29667440 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - April 19, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Corrigendum.
Authors: PMID: 29667450 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - April 19, 2018 Category: Neurology Tags: Brain Inj Source Type: research

A systematic review of neuroimaging findings in children and adolescents with sports-related concussion.
CONCLUSIONS: While MRI and CT are generally unrevealing, advanced neuroimaging techniques demonstrated neurometabolic, microstructural, and functional alterations following SRC in athletes younger than 19 years of age in the acute, subacute, and chronic phases of recovery. However, more studies are needed to fully understand the impact of SRC on the developing brain in children and adolescents. PMID: 29648462 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - April 16, 2018 Category: Neurology Tags: Brain Inj Source Type: research

'Reported concussion' time trends within two national health surveys over two decades.
CONCLUSIONS: The current pandemic of reported brain injury in Canada will have implications for health-care delivery. PMID: 29652525 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - April 16, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Searching for effective components of cognitive rehabilitation for children and adolescents with acquired brain injury: A systematic review.
Conclusions remain tentative due to small sample sizes of included studies heterogeneity regarding outcome measures, intervention and therapist variables, and patient characteristics. PMID: 29621405 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - April 6, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Treadmill associated head injuries on the rise: an 18 year review of U.S. emergency room visits.
Authors: Catapano JS, Chapman AJ, Farber SH, Horner LP, Morgan C, Brigeman S, Hendricks BK, Lu M, Fraser DR Abstract OBJECTIVE: The treadmill is the most commonly used aerobic exercise equipment with studies showing many gym-related injuries are attributed to treadmills. The purpose of this study is to examine the incidence of treadmill-associated head injuries within the US. METHODS: Retrospective data from 1997 to 2014 was collected via the National Electronic Injury Surveillance System, which provides annual es7timates of injuries associated with consumer products. Patients over 18 years who sustained t...
Source: Brain Injury - March 31, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Comparison of intensive versus conventional insulin therapy in traumatic brain injury: a meta-analysis of randomized controlled trials.
Authors: Núñez-Patiño RA, Zorrilla-Vaca A, Rivera-Lara L Abstract OBJECTIVE: To compare intensive insulin therapy (IIT) and conventional insulin therapy (CIT) on clinical outcomes of patients with traumatic brain injury (TBI). METHODS: MEDLINE, EMBASE, Google Scholar, ISI Web of Science, and Cochrane Library were systematically searched for randomized controlled trials (RCTs) comparing IIT to CIT in patients with TBI. Study-level characteristics, intensive care unit (ICU) events, and long-term functional outcomes were extracted from the articles. Meta-analysis was performed with random-effe...
Source: Brain Injury - March 29, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Vestibular and oculomotor findings in neurologically-normal, non-concussed children.
CONCLUSIONS: The provider should be aware that a proportion of non-concussed children may demonstrate failure on a single element of the vestibular and oculomotor exam. While this testing is of benefit to the acute care provider in diagnosing paediatric concussion, its utility is greatest in the context of an injury history with acute onset of concussion symptoms. PMID: 29584455 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - March 29, 2018 Category: Neurology Tags: Brain Inj Source Type: research

An investigation of white matter integrity and attention deficits following traumatic brain injury.
This study aimed to investigate the association between white matter tracts and multiple aspects of attention and working memory deficits in a relatively acute traumatic brain injury (TBI) sample. METHOD: Neuropsychological measures of attention and working memory were administered to 20 participants with complicated mild-to-very severe TBI and 20 control participants. Tract-based spatial statistics was used to assess fractional anisotropy (FA) and mean diffusivity (MD) of white matter tracts for 15 TBI participants and 20 controls. RESULTS: When compared to controls, participants with TBI were found to have lower FA (p 
Source: Brain Injury - March 24, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Music interventions in disorders of consciousness (DOC) - a systematic review.
CONCLUSIONS: More studies with a larger number of participants are needed as well as a consensus on key characteristics of effective short-term and long-term music interventions for DOC. PMID: 29565697 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - March 24, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Conscious status is associated with the likelihood of trauma centre care and mortality in patients with moderate-to-severe traumatic brain injury.
Authors: AlSulaim HA, Haring RS, Asemota AO, Smart BJ, Canner JK, Ejaz A, Efron DT, Velopulos CG, Haut ER, Schneider EB Abstract OBJECTIVE: To assess the relationship between The International Classification of Diseases, Ninth Revision, Clinical Modification-derived conscious status and mortality rates in trauma centres (TC) vs. non-trauma centres (NTC). METHODS: Patients in the 2006-2011 Nationwide Emergency Department Sample meeting, The Centers for Disease Control and Prevention criteria for traumatic brain injury (TBI), with head/neck Abbreviated Injury Scale (AIS) scores ≥3 were included. Loss of consci...
Source: Brain Injury - March 23, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Barriers and strategies for coordinating care among veterans with traumatic brain injury: a mixed methods study of VA polytrauma care team members.
CONCLUSION: Polytrauma care team members encounter barriers to care coordination for Veterans with TBI, and have developed strategies in response. Information sharing, provider workload, communication, and patient engagement will be critical to address in future efforts to enhance care coordination in this context. PMID: 29537883 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - March 20, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Autonomic cardiac control response to walking and executive cognitive task in adolescents with acquired brain injury and typically developed controls.
Authors: Sorek G, Shaklai S, Meyer S, Katz-Leurer M Abstract INTRODUCTION: Adolescents with acquired brain injury (ABI) present a range of physical and cognitive as well as cardiac autonomic control system (CACS) dysfunctions. AIM: To examine the CACS response to an executive task, a physical task and a combined physical and executive task, in adolescents with ABI and typically developed (TD) controls. METHODS: Included were two groups: The first group consisted of 17 adolescents (11-18 years) with ABI, during the in-patient or out-patient rehabilitation period. All were independent walkers. The second...
Source: Brain Injury - March 14, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Difficulty hearing in noise: a sequela of concussion in children.
CONCLUSIONS: Functional listening skills-such as the ability to understand speech in noise, and the ability to sustain performance over time in taxing auditory conditions-may be compromised in children with concussions. These impairments may exacerbate cognitive and academic challenges associated with concussion injuries, and should be considered in return-to-learn and return-to-play decisions. PMID: 29517389 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - March 10, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Decomposition of leg movements during overground walking in individuals with traumatic brain injury.
Authors: Austin HM, Balendra N, Langenderfer JE, Ustinova KI Abstract OBJECTIVE: Walking requires precise coordination of bilateral lower extremity motions at all joints. This ability can be affected by traumatic brain injury (TBI). The study investigated inter-joint coordination of lower extremities during overground walking after TBI. METHODS: Ten individuals with post-injury ataxia, postural stability and gait abnormalities, as well as 10 sex- and age-matched control subjects were involved in the study. Participants walked at self-selected speed in three experimental conditions: normal walking without any ad...
Source: Brain Injury - March 3, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Score on Coma Recovery Scale-Revised at admission predicts outcome at discharge in intensive rehabilitation after severe brain injury.
Authors: Portaccio E, Morrocchesi A, Romoli AM, Hakiki B, Taglioli MP, Lippi E, Di Renzone M, Grippo A, Macchi C Abstract OBJECTIVE: To assess the prognostic utility of the Coma Recovery Scale-Revised (CRS-R) in rehabilitation of patients surviving from severe brain injury. METHODS: In this prospective cohort study, all patients consecutively admitted to an Italian Intensive Rehabilitation Unit, with a diagnosis of unresponsive wakefulness syndrome (UWS) or minimally conscious state (MCS) due to acquired brain injury, underwent clinical evaluations using the Italian version of the CRS-R. At discharge, patients ...
Source: Brain Injury - February 28, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Concussion history is negatively associated with visual-motor force complexity: evidence for persistent effects on visual-motor integration.
CONCLUSION: Individuals exhibited linear decreases in visual-motor tracking force complexity with increasing numbers of concussions, influenced by both gender and a history of LOC. These findings indicate cumulative changes in the ways in which previously concussed individuals process and integrate visual information to guide behaviour. PMID: 29485290 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 28, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Delayed intracranial hemorrhage in the patient with blunt trauma on anticoagulant or antiplatelet agents: routine repeat head computed tomography is unnecessary.
CONCLUSIONS: Routine repeat head CT in patients with blunt trauma taking anticoagulant or antiplatelet agents is unnecessary. Incidence of DICH is low and, when found, DICH was clinically insignificant. We recommend close supervision in this population, especially those taking ASA alone or in combination with another anticoagulant. PMID: 29485294 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 28, 2018 Category: Neurology Tags: Brain Inj Source Type: research

"Five-layer gasket seal" watertight closure for reconstruction of the skull base in complex bilateral traumatic intraorbital meningoencephaloceles: a case report and literature review.
CONCLUSIONS: The diagnosis and treatment of complex intraorbital meningoencephalocele require careful attention. Resection of herniated tissue is suggested due to potential contamination. The "five-layer gasket seal" watertight closure technique is recommended for successful repair of the skull base in cases involving traumatic meningoencephalocele with complex skull base fractures. PMID: 29485295 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 28, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Measurement properties of the Chinese version of the Mental Fatigue Scale for patients with traumatic brain injury.
CONCLUSION: The CMFS provides reliable and valid information on mental fatigue for future research and clinical practice involving patients with traumatic brain injury. PMID: 29461861 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 22, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Mild traumatic brain injury: evaluation of olfactory dysfunction and clinical-neurological characteristics.
CONCLUSION: The possibility of olfactory dysfunction should be considered in any case of MTBI appears differently than expected, a minor head injury causes anosmia much more frequently than hyposmia. PMID: 29446651 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 17, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Post-concussive symptoms after a mild traumatic brain injury during childhood and adolescence.
CONCLUSIONS: PCSs are common 2 years post-mTBI in childhood or adolescence. Given this, additional intervention and support is needed for families post-injury. PMID: 29446658 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 17, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Chondroitinase ABC for neurological recovery after acute brain injury: systematic review and meta-analyses of preclinical studies.
CONCLUSIONS: The summary of published evidence suggests that ChABC treatment is effective in improving neurological outcomes in preclinical models of acute brain injury. However, more studies are needed for better assessment of the specific translational potential of ChABC. ABBREVIATIONS: AVM - Arteriovenous Malformation; ChABC - Chondroitinase ABC; CI - Confidence Interval; CSPG - Chondroitin Sulphate Proteoglycans; HKSJ - Hartung-Knapp-Sidik-Jonkman; MCA - Middle Cerebral Artery; NMD - Normalised Mean Difference; NSPC - Neural Stem/Progenitor Cells; PI - Prediction Interval; SD - Standard Deviation; SMD - Standardise...
Source: Brain Injury - February 15, 2018 Category: Neurology Tags: Brain Inj Source Type: research

An investigation of neuroinjury biomarkers after sport-related concussion: from the subacute phase to clinical recovery.
CONCLUSIONS: Our results are consistent with the increasing recognition that physiological recovery after SRC extends beyond clinical recovery. Blood biomarkers appear to be useful in elucidating the biology of brain restitution after SRC. However, their implementation requires mindfulness of factors such as academic stress, exercise, and injury heterogeneity. PMID: 29420083 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 10, 2018 Category: Neurology Tags: Brain Inj Source Type: research

The incidence of traumatic brain injury in Tehran, Iran.
CONCLUSION: The mechanism of TBI, the type of head injuries, and accompanying spine and abdominal injuries were significant prognostic factors in traumatic patients. PMID: 29405787 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 8, 2018 Category: Neurology Tags: Brain Inj Source Type: research

The value of the identification of predisposing factors for post-traumatic amnesia in management of mild traumatic brain injury.
CONCLUSION: CT findings: (traumatic focal HCs in the frontal and temporal lobes or more diffuse punctate HCs and skull base fractures), age, seizures and anticoagulation/antiplatelet therapy, were independent factors of PTA and could be used as predictive factors after mTBI. PMID: 29400569 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 7, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Analysis of serum cortisol to predict recovery in paediatric sport-related concussion.
CONCLUSION: Paediatric ice hockey players following SRC with abnormally low cortisol may be more susceptible to experiencing increase symptom burden and take longer to return to sport than players with population-based normal cortisol. PMID: 29400570 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 7, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Reliability of the balance error scoring system in a population with protracted recovery from mild traumatic brain injury.
CONCLUSION: BESS reliability appears to be high in a concussed cohort, regardless of age. Removing the two double-leg stance portions increases the ICC of the test without failing to identify balance deficits. PMID: 29393686 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 4, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Systematic review of high-level mobility training in people with a neurological impairment.
CONCLUSION: There is preliminary evidence to support the efficacy of interventions to improve high-level mobility skills in people with neurological impairments. Well-controlled research with a larger sample is required to provide sufficient evidence to change clinical practice. PMID: 29393688 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 4, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Zolpidem efficacy and safety in disorders of consciousness.
Authors: Machado C, Estévez M, Rodriguez-Rojas R Abstract Sutton and Clauss presented a detailed review about the effectiveness of zolpidem, discussing recoveries from brain damage due to strokes, trauma and hypoxia. A significant finding has been the unexpected and paradoxical increment of brain activity in vegetative state/unresponsive wakefulness syndrome (VS/UWS). On the contrary, zolpidem is considered one of the best sleep inducers in normal subjects. We have studied series of VS/UWS cases after zolpidem intake. We have demonstrated EEG activation, increment of BOLD signal in different brain regions, a...
Source: Brain Injury - February 4, 2018 Category: Neurology Tags: Brain Inj Source Type: research

A historical review of the evolution of the Tardieu Scale.
Authors: Morris SL, Williams G Abstract There are many clinical assessment tools that can be used to quantify spasticity, one feature of the Upper Motor Neurone (UMN) syndrome. The focus of this short paper is on three; the Tardieu Scale, the Modified Tardieu Scale and the Australian Spasticity Assessment Scale, because a fundamental concept of these tests is their velocity dependent nature. Other bedside assessments such as the Modified Ashworth Scale examine hypertonicity, another feature of the UMN syndrome, but in this instance, the stretching movement is not velocity dependent. The Tardieu Scale, while not off...
Source: Brain Injury - February 4, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Beyond anger: emotion regulation and social connectedness in veterans with traumatic brain injury.
CONCLUSIONS: Impairments in ER should be regarded as a risk factor for poor interpersonal outcomes, a target for mental health treatment and a focus for interventions aimed at improving psychological well-being in TBI. PMID: 29393692 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 4, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Rights language and disorders of consciousness: a call for advocacy.
Authors: Fins JJ, Wright MS Abstract Drawing upon sources in neuroethics, civil rights, and disability rights law, we argue for the reintegration of people with severe brain injury back into the nexus of their families and communities consistent with the Americans with Disabilities Act (ADA) and the UN Convention on the Rights of the Disabled, both of which call for the maximal integration of people with disability into society. To this end, we offer a rights-based argument to address the care of people with severe brain injury. Instead of viewing the provision of rehabilitation as a reimbursement issue, which it s...
Source: Brain Injury - February 4, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Assessment of olfactory function after traumatic brain injury: comparison of single odour tool with detailed assessment tool.
This study aimed to compare a brief single-odour identification tool (BSOIT) with a more detailed 12-odour assessment tool. MATERIALS/METHODS: One hundred seventy consecutive patients with TBI had their olfaction assessed using BSOIT and a 12-item tool at a single time point. The sensitivity and specificity of the BSOIT were calculated. RESULTS: The sensitivity and specificity of the BSOIT as compared to the Burghart tool were 57.5% and 100%, respectively, for all ODs (anosmia and hyposmia). The sensitivity and specificity for anosmia only were 93.5% and 96.7%, respectively. For the two tools, the Cohen's kappa coe...
Source: Brain Injury - February 4, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Untangling chronic pain and post-concussion symptoms: the significance of depression.
Authors: Snell DL, Martin R, Macleod AD, Surgenor LJ, Siegert RJ, Hay-Smith EJC, Melzer T, Hooper GJ, Anderson T Abstract OBJECTIVES: Post-concussion-like symptoms (PCS) are common in patients without a history of brain injury, such as those with chronic pain (CP). This exploratory study examined neuro-cognitive and psychological functioning in patients with PCS following mild traumatic brain injury (mTBI) or CP, to assess unique and overlapping phenomenology. METHODS: In this case-control study, participants (n = 102) with chronic symptoms after mTBI (n = 45) were matched with mTBI recovere...
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Patient perspectives on quality and access to healthcare after brain injury.
CONCLUSIONS: Additional efforts need to be made to improve access to appropriate healthcare and increase the ability for individuals to successfully navigate the healthcare system. Findings suggest several specific, low-cost modifications to healthcare delivery and strategies for improving medical self-management that can maximize long-term health maintenance for BI survivors. PMID: 29388840 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Prediction of lower extremity motor recovery in persons with severe lower extremity paresis after stroke.
Authors: Huang SL, Chen BB, Hsueh IP, Jeng JS, Koh CL, Hsieh CL Abstract OBJECTIVE: To investigate the extent of motor recovery and predict the prognosis of lower extremity (LE) recovery in patients with severe LE paresis after stroke Methods: 137 patients with severe LE paresis after stroke were recruited from a local medical centre. Voluntary LE movement was assessed with the LE subscale of the Stroke Rehabilitation Assessment of Movement (STREAM-LE). Univariate and stepwise regression analyses were used to investigate 25 clinical variables (including demographic, neuroimaging, and behavioural variables) for find...
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

The effects of concussion on rapid picture naming in children.
CONCLUSIONS: These findings affirm the presence of this naming latency effect in children, explore the duration of this effect over the course of recovery, and add nuance to inconsistently reported chronic naming deficits following concussion, informing recommendations for return to full academic and recreational participation. PMID: 29388844 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

The influence of post-acute rehabilitation length of stay on traumatic brain injury outcome: a retrospective exploratory study.
CONCLUSIONS: Results suggest that both, level of disability and injury chronicity, should be considered when determining LOS. Data also show an association between LOS and changes in the MPAI and CIQ. PMID: 29388849 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Neurophysiological and cognitive impairment following repeated sports concussion injuries in retired professional rugby league players.
Authors: Pearce AJ, Rist B, Fraser CL, Cohen A, Maller JJ Abstract BACKGROUND: Concussion is regarded as a common injury in rugby league, however no studies have explored the long-term neurophysiological and cognitive effects of repeated concussion injuries in this sport. METHODS: Former professional rugby athletes (n = 25) were compared to 25 age-matched participants with no history of a concussion. All participants completed standardised motor dexterity, reaction time, and cognitive tasks for working memory, associative learning and rule acquisition and reversal. Single-pulse transcranial magnetic s...
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

From 'miserable minority' to the 'fortunate few': the other end of the mild traumatic brain injury spectrum.
This study, as part of the UPFRONT-study, aimed to study the patients that report zero complaints early after injury, a group that we named the 'fortunate few'. We focused on their demographic, clinical and premorbid characteristics, and examined whether they would remain asymptomatic. Moreover, we investigated the influence of anxiety and depression (HADS), and determined outcome (GOS-E) and quality of life (WHOQOL-BREF) 1 year after injury. METHODS: Patients with MTBI (Glasgow Coma Scale score 13-15), without complaints 2 weeks after injury were included. Follow-up took place at 3, 6 and 12 months after inj...
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Effects of music production on cortical plasticity within cognitive rehabilitation of patients with mild traumatic brain injury.
CONCLUSION: Here, for the first time, we demonstrated behavioural improvements and functional brain changes after 8 weeks of playing piano on patients with mTBI having attention, memory and social interaction problems. We present evidence for a causal relationship between musical training and reorganisation of neural networks promoting enhanced cognitive performance. These results add a novel music-supported intervention within rehabilitation of patients with cognitive deficits following mTBI. PMID: 29388854 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Development of a simple driving simulator and determination of the reference range of normative performance.
CONCLUSIONS: We provide evidence that impaired performance on ≤2 items of the SiDS provides a sensitive criterion of 'driving fitness' in young adults after a TBI. PMID: 29388857 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Saved by the Pupillometer! - A role for pupillometry in the acute assessment of patients with traumatic brain injuries?
We present a case of a patient with seemingly irreversible demise from an acute traumatic subdural haematoma. This was determined by assessment of his pupils, which were non-reactive to light at the time of arrival to the neurosurgical theatre. He was transferred to the neurointensive care for brainstem death testing, where assessment by objective pupillometry determined that his pupils were in fact reactive. He made a good recovery following subsequent surgery to evacuate his subdural haematoma. We propose the widespread adoption of objective pupillometers in the assessment of acute head-injured patients and offer our cas...
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Results from a randomized trial evaluating a hospital-school transition support model for students hospitalized with traumatic brain injury.
CONCLUSION: The lack of significant findings in this study does not imply that effective hospital-to-school transition programming is unnecessary. Rather, the findings raise important questions regarding timing and dosage/intensity of intervention, appropriate measurement of outcomes, and fidelity of programme delivery. The study highlights difficulties involved in the conduct of community-based RCTs in the paediatric TBI population. PMID: 29388885 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 2, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Prognostic factors in childhood-acquired brain injury.
CONCLUSIONS: Duration of unconsciousness is the main long-term negative prognostic outcome factor. Anoxic brain damage, associated with longer periods of unconsciousness also heralds a less favourable outcome. PMID: 29381392 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 1, 2018 Category: Neurology Tags: Brain Inj Source Type: research

Diffuse axonal injury after traumatic brain injury is a prognostic factor for functional outcome: a systematic review and meta-analysis.
CONCLUSIONS: Presence of DAI on MRI in patients with TBI results in a higher chance of unfavourable outcome. With MRI grading, OR for unfavourable outcome increases threefold with every grade. Lesions in the corpus callosum in particular are associated with an unfavourable outcome. PMID: 29381396 [PubMed - as supplied by publisher] (Source: Brain Injury)
Source: Brain Injury - February 1, 2018 Category: Neurology Tags: Brain Inj Source Type: research