Effect of intravenous and topical laryngeal lidocaine on sore throat after extubation: a prospective randomized controlled study
CONCLUSIONS: Both topical laryngeal lidocaine and intravenous lidocaine before intubation have positive effects on preventing sore throat. Topical laryngeal route was superior to intravenous route. Chictr.org.cn ID: ChiCTR2100042442.PMID:38567609 | DOI:10.26355/eurrev_202403_35756 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: J Lin W-D Wang Q-Y Yang Y-L Wen J-H Yang W-Q Fan Y-B Zuo Source Type: research

Effect of intravenous and topical laryngeal lidocaine on sore throat after extubation: a prospective randomized controlled study
CONCLUSIONS: Both topical laryngeal lidocaine and intravenous lidocaine before intubation have positive effects on preventing sore throat. Topical laryngeal route was superior to intravenous route. Chictr.org.cn ID: ChiCTR2100042442.PMID:38567609 | DOI:10.26355/eurrev_202403_35756 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: J Lin W-D Wang Q-Y Yang Y-L Wen J-H Yang W-Q Fan Y-B Zuo Source Type: research

A Four-Arm Randomized Clinical Trial of Topical Pain Control for Sentinel Node Radiotracer Injections in Patients with Breast Cancer
CONCLUSION: In this randomized trial, no differences in patient-reported pain or satisfaction with treatment was observed between ice and other topical treatments. Providers found treatments using Buzzy® more difficult to administer. Given patient satisfaction and ease of administration, ice is a reasonable standard.PMID:38557909 | DOI:10.1245/s10434-024-15235-7 (Source: Ann Oncol)
Source: Ann Oncol - April 1, 2024 Category: Cancer & Oncology Authors: Alyssa A Wiener Jessica R Schumacher Scott B Perlman Lee G Wilke Meeghan A Lautner Laura M Bozzuto Bret M Hanlon Heather B Neuman Source Type: research

Peripheral Nerve Stimulation for a Refractory Case of Postherpetic Neuralgia in the Upper Limb: A Case Report
This report presents a patient with upper limb PHN who responded to peripheral nerve stimulation (PNS) after he failed to obtain sufficient pain relief with conservative management.PMID:38558725 | PMC:PMC10979704 | DOI:10.7759/cureus.55168 (Source: Herpes)
Source: Herpes - April 1, 2024 Category: Infectious Diseases Authors: Arun Kalava Simeon V Mihaylov Harriet Kaye Austin Saru Acharya Source Type: research

Targeted local anesthesia: a novel slow-release Fe3O4 –lidocaine–PLGA microsphere endowed with a magnetic targeting function
ConclusionMagnetically responsive lidocaine microspheres can prolong analgesia by slowly releasing lidocaine, which can be immobilized around the nerve by a magnetic field on the body surface, avoiding premature diffusion of the microspheres to surrounding tissues and improving drug targeting. (Source: Journal of Anesthesia)
Source: Journal of Anesthesia - April 1, 2024 Category: Anesthesiology Source Type: research

Sustainable Alternatives to Petroleum-Derived Excipients in Pharmaceutical Oil-in-Water Creams
AAPS PharmSciTech. 2024 Mar 27;25(4):68. doi: 10.1208/s12249-024-02784-z.ABSTRACTRecently, vast efforts towards sustainability have been made in the pharmaceutical industry. In conventional oil-in-water (O/W) cream formulations, various petroleum-based excipients, namely mineral oil and petrolatum, are commonly used. Natural or synthetic excipients, derived from vegetable sources, were explored as alternatives to petroleum-based excipients in prototype topical creams, with 1% (w/w) lidocaine. A conventional cream comprised of petroleum-derived excipients was compared to creams containing sustainable excipients in terms of ...
Source: AAPS PharmSciTech - March 28, 2024 Category: Drugs & Pharmacology Authors: Dana Gates Abu Zayed Md Badruddoza Md Ikhtiar Zahid Thean Yeoh Jaymin Shah Taylor Walsh Md Nurunnabi Source Type: research

Sustainable Alternatives to Petroleum-Derived Excipients in Pharmaceutical Oil-in-Water Creams
AAPS PharmSciTech. 2024 Mar 27;25(4):68. doi: 10.1208/s12249-024-02784-z.ABSTRACTRecently, vast efforts towards sustainability have been made in the pharmaceutical industry. In conventional oil-in-water (O/W) cream formulations, various petroleum-based excipients, namely mineral oil and petrolatum, are commonly used. Natural or synthetic excipients, derived from vegetable sources, were explored as alternatives to petroleum-based excipients in prototype topical creams, with 1% (w/w) lidocaine. A conventional cream comprised of petroleum-derived excipients was compared to creams containing sustainable excipients in terms of ...
Source: AAPS PharmSciTech - March 28, 2024 Category: Drugs & Pharmacology Authors: Dana Gates Abu Zayed Md Badruddoza Md Ikhtiar Zahid Thean Yeoh Jaymin Shah Taylor Walsh Md Nurunnabi Source Type: research

Sustainable Alternatives to Petroleum-Derived Excipients in Pharmaceutical Oil-in-Water Creams
AAPS PharmSciTech. 2024 Mar 27;25(4):68. doi: 10.1208/s12249-024-02784-z.ABSTRACTRecently, vast efforts towards sustainability have been made in the pharmaceutical industry. In conventional oil-in-water (O/W) cream formulations, various petroleum-based excipients, namely mineral oil and petrolatum, are commonly used. Natural or synthetic excipients, derived from vegetable sources, were explored as alternatives to petroleum-based excipients in prototype topical creams, with 1% (w/w) lidocaine. A conventional cream comprised of petroleum-derived excipients was compared to creams containing sustainable excipients in terms of ...
Source: AAPS PharmSciTech - March 28, 2024 Category: Drugs & Pharmacology Authors: Dana Gates Abu Zayed Md Badruddoza Md Ikhtiar Zahid Thean Yeoh Jaymin Shah Taylor Walsh Md Nurunnabi Source Type: research