Combined Supra-Inguinal Fascia Iliaca, Sciatic Nerve, and Posterior Femoral Cutaneous Nerve Blocks in Austere Settings for Hemodynamically Unstable Patients with Vascular Injuries from Weapon Wounds: A Case Series
CONCLUSION: The combined block technique for the Sciatic Nerve (SN), Posterior Femoral Cutaneous Nerve (PFCN), and the Supra-Inguinal Fascia Iliaca (SIFI) appears to be a safe anesthetic option for unstable or high-risk patients requiring lower limb surgery. Further research with a larger cohort is necessary to validate our findings and to potentially standardize this approach.PMID:38450003 | PMC:PMC10916515 | DOI:10.2147/LRA.S452367 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - March 7, 2024 Category: Anesthesiology Authors: Majaliwa Shabani Seydina Alioune Beye Abdoulaye Traore Xavier Raingeval Daouda Coulibaly Sophie Crespo Source Type: research

Subcutaneous injection of lidocaine around ischemic ankle provides safe and effective foot analgesia in patients with critical limb ischemia
CONCLUSION: Subcutaneous injection of lidocaine around the ischemic ankle affectively alleviated pain in patients with CLI without serious adverse effects under anticoagulant therapy.PMID:38452400 | DOI:10.1177/17085381241238841 (Source: Vascular)
Source: Vascular - March 7, 2024 Category: Surgery Authors: Akifumi Kanai Masatomo Ara Ryusei Saito Toshiaki Mishima Yuichiro Takahashi Source Type: research

Combined Supra-Inguinal Fascia Iliaca, Sciatic Nerve, and Posterior Femoral Cutaneous Nerve Blocks in Austere Settings for Hemodynamically Unstable Patients with Vascular Injuries from Weapon Wounds: A Case Series
CONCLUSION: The combined block technique for the Sciatic Nerve (SN), Posterior Femoral Cutaneous Nerve (PFCN), and the Supra-Inguinal Fascia Iliaca (SIFI) appears to be a safe anesthetic option for unstable or high-risk patients requiring lower limb surgery. Further research with a larger cohort is necessary to validate our findings and to potentially standardize this approach.PMID:38450003 | PMC:PMC10916515 | DOI:10.2147/LRA.S452367 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - March 7, 2024 Category: Anesthesiology Authors: Majaliwa Shabani Seydina Alioune Beye Abdoulaye Traore Xavier Raingeval Daouda Coulibaly Sophie Crespo Source Type: research

Subcutaneous injection of lidocaine around ischemic ankle provides safe and effective foot analgesia in patients with critical limb ischemia
CONCLUSION: Subcutaneous injection of lidocaine around the ischemic ankle affectively alleviated pain in patients with CLI without serious adverse effects under anticoagulant therapy.PMID:38452400 | DOI:10.1177/17085381241238841 (Source: Vascular)
Source: Vascular - March 7, 2024 Category: Surgery Authors: Akifumi Kanai Masatomo Ara Ryusei Saito Toshiaki Mishima Yuichiro Takahashi Source Type: research

Virtual Reality for the Management of Pain and Anxiety in Patients Undergoing Implantation of Pacemaker or Implantable Cardioverter Defibrillator: A Randomized Study
ConclusionVRH use improved pain and anxiety control during deep venous puncture compared to standard analgesia care, and allowed morphine consumption reduction. However, pain and anxiety were similar at the time of sub-cutaneous pocket creation. (Source: Journal of Medical Systems)
Source: Journal of Medical Systems - March 5, 2024 Category: Information Technology Source Type: research

Effect of intravenous lidocaine on the ED50 of propofol induction dose in elderly patients undergoing painless gastroscopy: a prospective, randomized, double-blinded, controlled study
ConclusionsThe administration of intravenous lidocaine to elderly patients undergoing painless gastroscopy resulted in a significant 40% reduction in the ED50 of propofol induction dose, which may be related to the decreased incidence of hypotension and injection pain, as well as the improved post-gastroscopy orientation recovery.Trial registrationChiCTR, ChiCTR2200065530. Registered on 08 November 2022. (Source: Perioperative Medicine)
Source: Perioperative Medicine - March 5, 2024 Category: Surgery Source Type: research

Virtual Reality for the Management of Pain and Anxiety in Patients Undergoing Implantation of Pacemaker or Implantable Cardioverter Defibrillator: A Randomized Study
ConclusionVRH use improved pain and anxiety control during deep venous puncture compared to standard analgesia care, and allowed morphine consumption reduction. However, pain and anxiety were similar at the time of sub-cutaneous pocket creation. (Source: Journal of Medical Systems)
Source: Journal of Medical Systems - March 5, 2024 Category: Information Technology Source Type: research

CORR Insights ®: Is Ultrasound-guided or Landmark-guided Intra-articular Lidocaine Injection More Effective for Pain Control in Anterior Shoulder Dislocation Reduction? A Randomized Controlled Trial
Clin Orthop Relat Res. 2024 Feb 29. doi: 10.1097/CORR.0000000000003020. Online ahead of print.NO ABSTRACTPMID:38421456 | DOI:10.1097/CORR.0000000000003020 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - February 29, 2024 Category: Orthopaedics Authors: Kwadwo A Owusu-Akyaw Source Type: research

CORR Insights ®: Is Ultrasound-guided or Landmark-guided Intra-articular Lidocaine Injection More Effective for Pain Control in Anterior Shoulder Dislocation Reduction? A Randomized Controlled Trial
Clin Orthop Relat Res. 2024 Feb 29. doi: 10.1097/CORR.0000000000003020. Online ahead of print.NO ABSTRACTPMID:38421456 | DOI:10.1097/CORR.0000000000003020 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - February 29, 2024 Category: Orthopaedics Authors: Kwadwo A Owusu-Akyaw Source Type: research

Retraction Note: Lidocaine alleviates cytotoxicity-resistance in lung cancer A549/DDP cells via down-regulation of miR-21
Mol Cell Biochem. 2024 Feb 26. doi: 10.1007/s11010-024-04971-9. Online ahead of print.NO ABSTRACTPMID:38407732 | DOI:10.1007/s11010-024-04971-9 (Source: Molecular and Cellular Biochemistry)
Source: Molecular and Cellular Biochemistry - February 26, 2024 Category: Biochemistry Authors: Qing Yang Zhi Zhang Haixia Xu Chuangen Ma Source Type: research

Minimizing pain in deer antler removal: Local anaesthetics in ZnO nanoparticle based collagen dressings as a promising solution
In this study, we investigated the performance of a ZnO collagen nanocomposites loaded with local anesthetics to improve wound management and alleviate pain associated with antler removal in red deer. The research involved the preparation of collagen nanocomposites with local anesthetics and testing the drug release rates using in vitro drug release tests. Pharmacokinetic analysis was performed to evaluate the total drug release from the collagen matrix in red deer after velvet removal. Additionally, the analgesic efficacy of these collagen nanocomposite dressings was assessed after antler removal in red deer. Functionaliz...
Source: European Journal of Pharmaceutics and Biopharmaceutics - February 26, 2024 Category: Drugs & Pharmacology Authors: Farzin Sahebjam Paul Chambers Kavitha Kongara Yi Zhang Nicholas Lopez Antony Jacob Preet Singh Sujay Prabakar Source Type: research

Minimizing pain in deer antler removal: Local anaesthetics in ZnO nanoparticle based collagen dressings as a promising solution
In this study, we investigated the performance of a ZnO collagen nanocomposites loaded with local anesthetics to improve wound management and alleviate pain associated with antler removal in red deer. The research involved the preparation of collagen nanocomposites with local anesthetics and testing the drug release rates using in vitro drug release tests. Pharmacokinetic analysis was performed to evaluate the total drug release from the collagen matrix in red deer after velvet removal. Additionally, the analgesic efficacy of these collagen nanocomposite dressings was assessed after antler removal in red deer. Functionaliz...
Source: European Journal of Pharmaceutics and Biopharmaceutics - February 26, 2024 Category: Drugs & Pharmacology Authors: Farzin Sahebjam Paul Chambers Kavitha Kongara Yi Zhang Nicholas Lopez Antony Jacob Preet Singh Sujay Prabakar Source Type: research

Is it possible to extract primary maxillary molars without palatal injection?: a controlled clinical trial
ConclusionsWhile the pain reported following administration of anesthesia was found to be higher in the groups receiving palatal anesthesia, no difference was found between the groups in the pain reported after tooth extraction.Clinical relevanceExtraction of maxillary primary molars is possible without palatal injection by injecting 4% articaine or 2% lidocaine into the buccal vestibule of the tooth with a waiting time of 5 or 8  min. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - February 26, 2024 Category: Dentistry Source Type: research

Lower Dose of 5  mL of 1% Lidocaine is More Suitable than the Conventional 10 mL for Caudal Block in Transrectal Prostate Biopsy: A Retrospective Cohort Study
CONCLUSIONS: Our results suggest that 5 mL of 1% lidocaine may be more suitable than 10 mL for caudal block during transrectal prostate biopsy.PMID:38389652 | PMC:PMC10881246 | DOI:10.1155/2024/9331738 (Source: Advances in Urology)
Source: Advances in Urology - February 23, 2024 Category: Urology & Nephrology Authors: Norichika Ueda Mototaka Sato Shunsuke Mori Atsuki Matsukawa Yuta Oki Yuma Kujime Ryoya Mizuno Hiromu Horitani Tetsuya Yamamoto Shota Fukae Mitsuhiro Yoshinaga Makoto Matsushita Mai Akiyama Satoshi Kamido Ayako Honda Jiro Nakayama Norihide Tei Osamu Miyake Source Type: research