Dual-Tracer Positron-Emission Tomography Using Prostate-Specific Membrane Antigen and Fluorodeoxyglucose for Staging of Prostate Cancer: A Systematic Review
The objective of this study was to review the available evidence for patients undergoing both FDG and PSMA PET for PCa staging at initial diagnosis and in recurrent disease. A systematic literature review was performed for studies with direct, intraindividual comparison of PSMA and FDG PET for staging of PCa. Assessment for radioligand therapy eligibility was not considered. Risk of bias was assessed. 543 citations were screened and assessed. 13 case reports, three retrospective studies, and one prospective study were included. FDG after PSMA PET improved the detection of metastases from 65% to 73% in high-risk early castr...
Source: Advances in Urology - August 30, 2021 Category: Urology & Nephrology Authors: Stephen McGeorge Michael Kwok Andrew Jiang Louise Emmett David A Pattison Paul A Thomas John W Yaxley Matthew J Roberts Source Type: research

Evaluation of the Extent of Primary Buccal Mucosal Graft Contracture in Augmentation Urethroplasty for Stricture Urethra: A Prospective Observational Study at a Tertiary Healthcare Centre
CONCLUSION: Primary buccal mucosal graft contracture is around 8.4% in length and 9.5% in width. It would be better to mark wider than necessary while harvesting buccal mucosa so that tension-free anastomosis is performed.PMID:34341663 | PMC:PMC8325577 | DOI:10.1155/2021/9913452 (Source: Advances in Urology)
Source: Advances in Urology - August 3, 2021 Category: Urology & Nephrology Authors: A BhalaguruIyyan P Puvai Murugan Chandranaath C Alakhananda B M Zeeshan Hameed Source Type: research

Randomized Controlled Trial of Laparoscopic versus Open Radical Cystectomy in a Laparoscopic Na ïve Center
CONCLUSION: Laparoscopic radical cystectomy was associated with comparable postoperative outcomes when compared to ORC in the first laparoscopic cystectomy experience in our center. Benefitting from the assistance of an experienced laparoscopic surgeon is recommended to shorten the learning curve.PMID:34306069 | PMC:PMC8279872 | DOI:10.1155/2021/4731013 (Source: Advances in Urology)
Source: Advances in Urology - July 26, 2021 Category: Urology & Nephrology Authors: Waleed Mohamed Fadlalla Ayman Hanafy Mahmoud Abdelhakim Hatem Aboulkassem El Sayed Ashraf Ahmed Abdelbary Source Type: research

Penile Hemodynamic Response to Phosphodiesterase Type V Inhibitors after Cavernosal Sparing Inflatable Penile Prosthesis Implantation: A Prospective Randomized Open-Blinded End-Point (PROBE) Study
In this study, we aimed to compare the conventional and cavernosal sparing techniques regarding cavernosal artery preservation. Overall, 33 patients underwent inflatable penile prosthesis implantation with Coloplast Titan Touch® three-piece inflatable penile implants. 16 patients had conventional implantations with serial vigorous dilatations, while 17 patients were implanted with the cavernosal sparing technique, consisting of a single minimal corporal dilatation after an intraoperative intracavernosal injection (ICI) of Alprostadil. Postoperatively, a penile duplex Doppler ultrasound study was performed. Whenever a c...
Source: Advances in Urology - July 14, 2021 Category: Urology & Nephrology Authors: Adham Zaazaa Michaela Bayerle-Eder Ramzy Elnabarawy Mahmoud Elbitar Taymour Mostafa Source Type: research

Understanding the Impact of Urinary Incontinence in Persons with Dementia: Development of an Interdisciplinary Service Model
CONCLUSION: UI can be distressing for persons with dementia. Care partners were concerned about loss of independence and early nursing home admission. Awareness of bladder and bowel services should be increased.PMID:34239557 | PMC:PMC8238624 | DOI:10.1155/2021/9988056 (Source: Advances in Urology)
Source: Advances in Urology - July 9, 2021 Category: Urology & Nephrology Authors: Patrick Julieb ø-Jones Elizabeth Coulthard Elizabeth Mallam Hilary Archer Marcus J Drake Source Type: research

Efficacy of Neoadjuvant Targeted Therapy in Treatment of Patients with Localised Clear-Cell Renal Cell Carcinoma
This study aimed to evaluate the efficacy of neoadjuvant targeted therapy (TT) in patients with localised clear-cell renal cell carcinoma (RCC).MATERIALS AND METHODS: A special randomised trial was planned and conducted by the Research Department of Plastic and Reconstructive Oncology in the National Cancer Institute of Ukraine for testing the clinical efficacy of neoadjuvant TT in the treatment of clear-cell localised RCC, and the primary endpoint was tumour response evaluation after TT. The secondary endpoints included evaluation of dependence between the use of neoadjuvant TT and the probability of partial nephrectomy a...
Source: Advances in Urology - May 20, 2021 Category: Urology & Nephrology Authors: O A Voylenko O E Stakhovsky I V Vitruk O A Kononenko M V Pikul S L Semko E O Stakhovsky Source Type: research