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Efficacy of Articaine versus Lidocaine in Supplemental Infiltration for Mandibular First versus Second Molars with Irreversible Pulpitis: A Prospective, Randomized, Double-blind Clinical Trial
ConclusionsThe success rate for IANB with 4% articaine was 25%. Articaine and lidocaine had similar success rates for supplemental infiltration in first molars, whereas articaine was significantly more successful for second molars. However, because BI often did not provide profound pulpal anesthesia, additional techniques including intraosseous anesthesia may still be required. (Source: Dental Technology Blog)
Source: Dental Technology Blog - February 16, 2018 Category: Dentistry Source Type: news

CidalEaze (Lidocaine 3% HCL Cream) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 1, 2018 Category: Drugs & Pharmacology Source Type: news

Low-level laser therapy and anesthetic infiltration for orofacial pain in patients with fibromyalgia: a randomized clinical trial.
CONCLUSIONS:The LLLT by GaAlAs and anesthetic infiltration of lidocaine 2% were equally effective to control orofacial pain in FM individuals. (Source: Dental Technology Blog)
Source: Dental Technology Blog - December 29, 2017 Category: Dentistry Source Type: news

Case series: treating cannabinoid hyperemesis syndrome with capsaicin cream
3 out of 5 stars Resolution of cannabis hyperemesis syndrome with topical capsaicin in the emergency department: a case series. Dezieck L et al. Clin Toxicol 2017 Sep;55:908-913. Abstract  Cannabis hyperemesis syndrome (CHS) is a form of cyclic vomiting characterized by: chronic marijuana use recurrent vomiting, and lack of alternate explanation for symptoms A striking feature is that although CHS-induced nausea and vomiting are frequently resistant to standard antiemetics such as ondansetron, patients often report that very hot showers or baths relieve their symptoms. Several years ago, Jeff Lapoint ...
Source: The Poison Review - December 5, 2017 Category: Toxicology Authors: Leon Gussow Tags: Medical cannabinoid hyperemesis syndrome capsaicin treatment TRPV1 receptor Source Type: news

Scilex seeks EU nod for ZTlido lidocaine patch
Sorrento Therapeutics (NSDQ:SRNE) subsidiary Scilex Pharmaceuticals said today that it filed a marketing authorization application seeking approval for its ZTlido lidocaine patch. The San Diego, Calif.-based company said it is pursuing a hybrid regulatory pathway with the Medicines and Healthcare Products Regulatory Agency in the U.K., which will serve as the lead review agency. The company also plans to file for review in other countries, including Germany, France, Spain, Italy and Ireland. Get the full story at our sister site, Drug Delivery Business News. The post Scilex seeks EU nod for ZTlido ...
Source: Mass Device - November 14, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Pain Management Pharmaceuticals Regulatory/Compliance Wall Street Beat Scilex Pharmaceuticals Sorrento Therapeutics Source Type: news

Ridge Properties DBA Pain Relief Naturally Issues Voluntary Nationwide Recall of all lots of Naturally HL Bedsore Cream, Pretat by TAT Balm Carbomer Free Gel, & All Naturally HL Hemorrhoid products due to manufacturing concerns at the facility
Ridge Properties DBA Pain Relief Naturally voluntarily recalls all lots within expiry of Naturally HL Bedsore Relief Cream, Extra Strength PreTAT by TAT Balm Carbomer Free Gel and Extra Strength Naturally HL Hemorrhoid Numbing with Lidocaine. (Source: NCCAM Featured Content)
Source: NCCAM Featured Content - November 9, 2017 Category: Complementary Medicine Authors: NCCIH Source Type: news

Ridge Properties DBA Pain Relief Naturally Issues Voluntary Nationwide Recall of all lots of Naturally HL Bedsore Cream, Pretat by TAT Balm Carbomer Free Gel, & All Naturally HL Hemorrhoid products due to manufacturing concerns at the facility
Ridge Properties DBA Pain Relief Naturally is voluntarily recalling all lots within expiry of Naturally HL Bedsore Relief Cream, Extra Strength PreTAT by TAT Balm Carbomer Free Gel and Extra Strength Naturally HL Hemorrhoid Numbing with Lidocaine manufactured by Ridge Properties dba Pain Relief Naturally, Salem, Oregon to the consumer level. These products are being recalled after an FDA inspection found significant violations of current good manufacturing practice regulations. (Source: Food and Drug Administration)
Source: Food and Drug Administration - November 3, 2017 Category: Food Science Source Type: news

Lidocaine Hydrochloride (Xylocaine) and Dextrose Injection Solution-Premix Bags (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - November 2, 2017 Category: Drugs & Pharmacology Source Type: news

Lidocaine Hydrochloride (Xylocaine) and Dextrose Injection Solution-Premix Bags (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 25, 2017 Category: Drugs & Pharmacology Source Type: news

Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine (Updated - Currently in Shortage
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 23, 2017 Category: Drugs & Pharmacology Source Type: news

Inserting a cannula into a vein
(Deutsches Aerzteblatt International) Patients who are given a local anesthetic before having a venous cannula inserted have a clearly reduced sensation of pain when larger gauge cannulas are used. Compared with intradermal lidocaine infusion, the use of vapocoolant spray has the advantage that the rate of venepuncture failures is lower. This is the conclusion reached by Dirk R ü sch and coauthors from Marburg University based on a randomized controlled trial. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 13, 2017 Category: International Medicine & Public Health Source Type: news

Auburn therapeutic company receives FDA drug approval
Vitruvias Therapeutics LLC, an Auburn-based drug company, has received approval of a new drug application from the U.S. Food and Drug Administration for a new drug. Vitruvias developed the drug with Sunny Pharmtech, a Taiwan-based API and drug development company. Sunny Pharmtech leaders said the jointly filed application received approval quickly. The drug, lidocaine ointment USP 5 percent, is the first generic approval for both companies and is also part o f a joint development agreement that… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - September 29, 2017 Category: Health Management Authors: Tyler Patchen Source Type: news

Auburn therapeutic company receives FDA drug approval
Vitruvias Therapeutics LLC, an Auburn-based drug company, has received approval of a new drug application from the U.S. Food and Drug Administration for a new drug. Vitruvias developed the drug with Sunny Pharmtech, a Taiwan-based API and drug development company. Sunny Pharmtech leaders said the jointly filed application received approval quickly. The drug, lidocaine ointment USP 5 percent, is the first generic approval for both companies and is also part o f a joint development agreement that… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 29, 2017 Category: Biotechnology Authors: Tyler Patchen Source Type: news

Your NEJM Group Today: Eradicating TB in U.S. / Lidocaine for IUD Insertion / Pennsylvania Internist Opportunities (FREE)
By the Editors Here's what we chose for you from NEJM Group today:NEJM Audio … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 21, 2017 Category: Primary Care Source Type: news

Lidocaine Nerve Block Reduces the Pain of IUD Insertion in Young Women Lidocaine Nerve Block Reduces the Pain of IUD Insertion in Young Women
Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 8, 2017 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Sorrento Therapeutics, Inc. Submits NDA For ZTlido(TM) Next-Generation Lidocaine Patch
SAN DIEGO, Aug. 29, 2017 -- (Healthcare Sales & Marketing Network) -- Sorrento Therapeutics, Inc. (NASDAQ: SRNE) ("Sorrento"), announced today that SCILEX Pharmaceuticals Inc. ("SCILEX"), a majority-owned subsidiary of Sorrento, resubm... Biopharmaceuticals, Drug Delivery, FDA Sorrento Therapeutics, SCILEX Pharmaceuticals, ZTlido, lidocaine patch (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 29, 2017 Category: Pharmaceuticals Source Type: news

Sorrento seeks FDA nod for lidocaine patch
Sorrento Therapeutics (NSDQ:SRNE) said today that its subsidiary Scilex Pharmaceuticals resubmitted the new drug application for its lidocaine patch, ZTlido, to the FDA. The San Diego, Calif.-based company is developing the drug-device product for the relief of pain associated with post-herpetic neuralgia. Get the full story at our sister site, Drug Delivery Business News. The post Sorrento seeks FDA nod for lidocaine patch appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - August 29, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Food & Drug Administration (FDA) Pain Management Pharmaceuticals Regulatory/Compliance Wall Street Beat Scilex Pharmaceuticals Sorrento Therapeutics Source Type: news

Sorrento Therapeutics, Inc. Submits NDA For ZTlido Next-Generation Lidocaine Patch
SAN DIEGO, Aug. 29, 2017 /PRNewswire/ -- Sorrento Therapeutics, Inc. (NASDAQ: SRNE) ( " Sorrento " ), announced today that SCILEX Pharmaceuticals Inc. ( " SCILEX " ), a majority-owned subsidiary of Sorrento, resubmitted the NDA and responded to all of FDA... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - August 29, 2017 Category: Drugs & Pharmacology Source Type: news

Lignospan Standard (Lidocaine HCl 2% and Epinephrine Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 10, 2017 Category: Drugs & Pharmacology Source Type: news

Lignospan Forte (Lidocaine HCl 2% and Epinephrine for Injection) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 9, 2017 Category: Drugs & Pharmacology Source Type: news

Lignospan Standard (Lidocaine HCl 2% and Epinephrine Injection) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 9, 2017 Category: Drugs & Pharmacology Source Type: news

Pliaglis (Lidocaine and Tetracaine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 7, 2017 Category: Drugs & Pharmacology Source Type: news

Lidoderm (Lidocaine Patch 5%) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 3, 2017 Category: Drugs & Pharmacology Source Type: news

Restylane Lyft with Lidocaine (Sterile Gel of Hyaluronic Acid) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 22, 2017 Category: Drugs & Pharmacology Source Type: news

Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - June 21, 2017 Category: Drugs & Pharmacology Source Type: news

Restylane Silk (Lidocaine 0.3% Injectable Gel) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 21, 2017 Category: Drugs & Pharmacology Source Type: news

Restylane-L (Hyaluronic Acid Dermal Filler Injectable Gel with 0.3% Lidocaine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 21, 2017 Category: Drugs & Pharmacology Source Type: news

Scilex touts head-to-head study of lidocaine pain-relief patch
Sorrento Therapeutics (NSDQ:SRNE) subsidiary Scilex Pharmaceuticals touted data today from a head-to-head clinical adhesion study of its ZTlido lidocaine patch, comparing it to the EU reference product, Versatis. ZTlido is a lidocaine patch in development for the treatment of post-herpetic neuralgia – a severe neuropathic pain condition that affects elderly people and patients who have had a Shingles infection, HIV/AIDS or cancer. The anhydrous patch contains just 36 milligrams of lidocaine, compared to Lidoderm and Versatis which each have 700 milligrams of the painkiller. Get the full story at our sister site, Drug...
Source: Mass Device - June 19, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Drug-Device Combinations Pain Management Pharmaceuticals Wall Street Beat Scilex Pharmaceuticals Sorrento Therapeutics Source Type: news

Akten (Lidocaine Hydrochloride Ophthalmic Gel) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 8, 2017 Category: Drugs & Pharmacology Source Type: news

Lidocaine Hydrochloride (Xylocaine) Injection (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - May 18, 2017 Category: Drugs & Pharmacology Source Type: news

Why People With A Treatable Flesh-Eating Disease Don't Want The Cure
This article is part of HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to fight them. UTUT FOREST, Kenya ― Amos Kiptui is no stranger to hardship. He was born in a cave 27 years ago and still lives in one, despite run-ins with wild buffalo, deadly snakes, leopards and lions.  So when thick, itchy welts began to appear on Kiptui’s right cheek, he took a sharp rock and scraped off layers of his skin, then packed the bleeding wound with traditional medicine made from bitter leaves.  “You put the leaves on a piece of iron and make a fire,&r...
Source: Healthy Living - The Huffington Post - May 2, 2017 Category: Consumer Health News Source Type: news

The Cure For This Flesh-Eating Disease Makes Grown Men Run And Hide
This article is part of HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to fight them. UTUT FOREST, Kenya ― Amos Kiptui is no stranger to hardship. He was born in a cave 27 years ago and still lives in one, despite run-ins with wild buffalo, deadly snakes, leopards and lions.  So when thick, itchy welts began to appear on Kiptui’s right cheek, he took a sharp rock and scraped off layers of his skin, then packed the bleeding wound with traditional medicine made from bitter leaves.  “You put the leaves on a piece of iron and make a fire,&r...
Source: Healthy Living - The Huffington Post - May 2, 2017 Category: Consumer Health News Source Type: news

Lidocaine Hydrochloride (Xylocaine) Injection (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 6, 2017 Category: Drugs & Pharmacology Source Type: news

Oraqix (Lidocaine and Prilocaine Periodontal Gel) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 20, 2017 Category: Drugs & Pharmacology Source Type: news

Simple Steps Reduce Pain During IV Placement in Children Simple Steps Reduce Pain During IV Placement in Children
Quality improvement methods increased use of jet-injected lidocaine in a pediatric emergency department, with robust results, researchers said.Medscape Medical News (Source: Medscape Emergency Medicine Headlines)
Source: Medscape Emergency Medicine Headlines - March 9, 2017 Category: Emergency Medicine Tags: Pediatrics News Source Type: news

Research Highlights from NAEMSP Annual Meeting Presented at EMS Today 2017
The National Association of EMS Physicians (NAEMSP) Annual Meeting is one of the foremost forums to encourage, share and expand research in EMS and prehospital care. Paul Rostykus, MD, MPH, the immediate past program committee chair, who orchestrated the 2016 and 2017 NAEMSP meetings, presented a summary at EMS Today 2017 of the top research from the 2017 NAEMSP Annual Meeting held in New Orleans last month. Rostykus highlighted the award-winning abstracts from the 2017 NAEMSP annual meeting and the ever-popular Top Five Articles presentation. Five of the first six oral presentations of the top-judged abstracts covered car...
Source: JEMS Administration and Leadership - February 25, 2017 Category: Emergency Medicine Authors: JEMS Staff Tags: Administration and Leadership EMS Today Source Type: news

Corey Slovis Presents Important Clinical Articles at EMS Today 2017
Keeping up with the ever-increasing medical literature that is directly applicable to EMS is growing more difficult each day. More and more journals in more and more specialties are publishing articles that affect our care in the field. At EMS Today 2017, Dr. Corey Slovis—who chairs the department of emergency medicine at Vanderbilt University Medical Center and is medical director of the Nashville fire department and international airport—presented a number of potentially practice-changing articles in his session, The Most Important Published Articles for EMS Providers. Slovis discussed the recent New England ...
Source: JEMS Patient Care - February 23, 2017 Category: Emergency Medicine Authors: JEMS Staff Tags: Patient Care EMS Today Source Type: news

I.V. Lidocaine in a Colorectal Surgery ERAS Program I.V. Lidocaine in a Colorectal Surgery ERAS Program
This study aimed to assess the role of perioperative lidocaine in an enhanced recovery after surgery (ERAS) program for colorectal surgery.BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 22, 2017 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Friday Highlights: 2017 EMS State of the Science Gathering of Eagles XVIX
The 19th Annual EMS State of the Science: Gathering of Eagles Conference, “dedicated to the men and women of EMS who advocate daily for the sick and injured,” began today, packed with 85 topics, faculty and attendees ready to dive into and learn about the latest in EMS and prehospital care. The conference began at 7:30 a.m. with the conference overview and philosophy presented by Raymond L. Fowler, MD—officially dubbed “The First Eagle”—and course coordinator, Paul E. Pepe, MD, MPH. Top 5 Studies of the Year The conference began with a customary review of “The Five Most Important ...
Source: JEMS: Journal of Emergency Medical Services News - February 17, 2017 Category: Emergency Medicine Authors: A.J. Heightman, MPA, EMT-P Tags: News Administration and Leadership Source Type: news

Friday Highlights: 2017 EMS State of the Science Gathering of Eagles XVIX
The 19th Annual EMS State of the Science: Gathering of Eagles Conference, “dedicated to the men and women of EMS who advocate daily for the sick and injured,” began today, packed with 85 topics, faculty and attendees ready to dive into and learn about the latest in EMS and prehospital care. The conference began at 7:30 a.m. with the conference overview and philosophy presented by Raymond L. Fowler, MD—officially dubbed “The First Eagle”—and course coordinator, Paul E. Pepe, MD, MPH. Top 5 Studies of the Year The conference began with a customary review of “The Five Most Important ...
Source: JEMS Administration and Leadership - February 17, 2017 Category: Emergency Medicine Authors: A.J. Heightman, MPA, EMT-P Tags: News Administration and Leadership Source Type: news

Ropivacaine: Less Pain, Hemorrhage Risk During Vitrectomy Ropivacaine: Less Pain, Hemorrhage Risk During Vitrectomy
Despite a similar effectiveness to bupivacaine, lidocaine, and a solution of both, ropivacaine had lower rates of postoperative pain and lower rates of hemorrhage in a randomized controlled trial.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 10, 2017 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

FTC, Endo propose agreement to resolve pay-for-delay dispute
Endo International and the Federal Trade Commission filed a joint motion in the U.S. District Court in California Monday seeking approval of proposal that would resolve all disputes between the pharmaceutical company and the federal agency relating to the alleged "pay-for-delay" patent infringement settlements Endo entered into with generic drug companies. Those settlements involved Lidoderm, a topical patch used to relieve pain associated with a complication of shingles known as post-herpetic neuralgia,… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - January 23, 2017 Category: American Health Authors: John George Source Type: news

FTC, Endo propose agreement to resolve pay-for-delay dispute
Endo International and the Federal Trade Commission filed a joint motion in the U.S. District Court in California Monday seeking approval of proposal that would resolve all disputes between the pharmaceutical company and the federal agency relating to the alleged "pay-for-delay" patent infringement settlements Endo entered into with generic drug companies. Those settlements involved Lidoderm, a topical patch used to relieve pain associated with a complication of shingles known as post-herpetic neuralgia,… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - January 23, 2017 Category: Biotechnology Authors: John George Source Type: news

Intraperitoneal Instillation of Lidocaine Cuts Post-Cesarean Pain Intraperitoneal Instillation of Lidocaine Cuts Post-Cesarean Pain
Intraperitoneal instillation of lidocaine improves the management of early postoperative pain after a cesarean delivery and reduces the number of women requesting opioids in the immediate postpartum period, according to researchers in Canada.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - January 9, 2017 Category: Surgery Tags: Ob/Gyn & Women ' s Health News Source Type: news

Synera (Lidocaine and Tetracaine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 29, 2016 Category: Drugs & Pharmacology Source Type: news

How to Confirm Ankle Joint Penetration
Suspicious lacerations should be investigated, even if the X-ray is normal. A step-by-step pictorial guide. It is a busy Friday evening in the emergency department when you get called to the resuscitation bay for a 14-year-old female who was the restrained back seat passenger in a rollover motor vehicle crash. After a quick call to your significant other to ensure that your daughter is safe in bed, you proceed to evaluate this young patient. You are once again amazed by modern safety technology with the minimal amount of head, torso and abdominal trauma on this patient. After a thorough initial inspection you find that the...
Source: EPMonthly.com - December 28, 2016 Category: Emergency Medicine Authors: Logan Plaster Tags: Uncategorized Source Type: news

Topical Lidocaine Could Help Make Infant Vaccines Less Painful (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Topically applied lidocaine may help ease vaccination pain in infants, according to a study in the Canadian Medical Association Journal.Roughly 350 … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - December 12, 2016 Category: Primary Care Source Type: news

Anesthetic cream best for relieving vaccination pain in infants
For babies under age one year, lidocaine cream, combined with a small amount of sugar given by mouth and infant soothing, can help relieve pain from routine vaccinations, according to a study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 12, 2016 Category: Science Source Type: news

Spoonful of sugar alone may not ease babies' vaccination pain
What's the best way to ease the pain of a vaccination for babies? A randomized control trial at SickKids in Toronto found that a little bit of topical lidocaine cream and a sip of sugar does the trick. (Source: CBC | Health)
Source: CBC | Health - December 12, 2016 Category: Consumer Health News Tags: News/Health Source Type: news