The anterior cingulate cortex and its interface with the dorsal periaqueductal grey regulating nitric oxide-mediated panic-like behaviour and defensive antinociception
Neuropharmacology. 2023 Dec 30;245:109831. doi: 10.1016/j.neuropharm.2023.109831. Online ahead of print.ABSTRACTThe anterior cingulate cortex (ACC) Cg1 (24b) area modulates glutamate-mediated unconditioned fear and antinociception organised by hypothalamus. However, it remains unknown whether 24b area also modulates these latter defensive responses through connections with the dorsal periaqueductal grey matter (dPAG), a midbrain structure implicated in the genesis of innate fear-induced defence. The aim of this work is to examine the correlation between the behavioural effects of intra-ACC microinjections of vehicle, NMDA ...
Source: Neuropharmacology - December 31, 2023 Category: Drugs & Pharmacology Authors: Luiz Luciano Falconi-Sobrinho Tayllon Dos Anjos-Garcia Mac ário Arosti Rebelo Paloma Molina Hernandes Rafael Carvalho Almada Jose Eduardo Tanus-Santos Norberto Cysne Coimbra Source Type: research
Experience from a single-center study on multimodal medication therapy for patients with complex regional pain syndrome
CONCLUSIONS: Our multimodal medication therapy algorithm effectively controlled pain in patients with CRPS. However, further prospective studies with large sample sizes and randomized controlled trials are needed for more accurate generalization.PMID:38160336 | DOI:10.3233/BMR-230179 (Source: Journal of Back and Musculoskeletal Rehabilitation)
Source: Journal of Back and Musculoskeletal Rehabilitation - December 31, 2023 Category: Orthopaedics Authors: Donghwi Park Jin-Woo Choi Min Cheol Chang Source Type: research
Analgesic Effects of Different Local Infiltration Anesthesia Techniques Combined with Femoral Nerve Block in Patients Undergoing Total Knee Arthroplasty: A Randomized Controlled Clinical Trial
CONCLUSION: When combined with FNB, intra-articular injection offers a superior analgesic effect and favorable recovery compared to periarticular injection and separate application of FNB.PMID:38148969 | PMC:PMC10750774 | DOI:10.2147/LRA.S436767 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - December 27, 2023 Category: Anesthesiology Authors: Yong-Kang Gui Rui Xiao Ya-Ru Luo Yang Liu Xin Da Si-Hui Zhu De-Wen Shi Xu-Dong Hu Guang-Hong Xu Source Type: research
