The Effect of Laser-Resistant Endotracheal Tube Design on Airflow Dynamics: A Benchtop and Clinical Study
CONCLUSION: The benchtop model demonstrated increased resistance in the LRSS-ET compared to the LRAS-ET at all comparable sizes. This finding is supported by retrospective ventilatory pressures during laser airway surgery, which show significantly increased PIPs when comparing identically sized inner diameters. Given the equivocal turbulence intensity data, these differences in resistance and pressures are likely caused by wall roughness and intraluminal presence of tubing, not inlet or outlet geometries. The decreased PIPs of the LRAS-ET should assist in following lung protective ventilator management strategies and reduc...
Source: The Annals of Otology, Rhinology, and Laryngology - March 16, 2024 Category: ENT & OMF Authors: Jessica M L Pagel Adithya Reddy Lucy Fitzgerald Mohamed Tiouririne Patrick O McGarey Daniel B Quinn James J Daniero Source Type: research

The Effect of Laser-Resistant Endotracheal Tube Design on Airflow Dynamics: A Benchtop and Clinical Study
CONCLUSION: The benchtop model demonstrated increased resistance in the LRSS-ET compared to the LRAS-ET at all comparable sizes. This finding is supported by retrospective ventilatory pressures during laser airway surgery, which show significantly increased PIPs when comparing identically sized inner diameters. Given the equivocal turbulence intensity data, these differences in resistance and pressures are likely caused by wall roughness and intraluminal presence of tubing, not inlet or outlet geometries. The decreased PIPs of the LRAS-ET should assist in following lung protective ventilator management strategies and reduc...
Source: The Annals of Otology, Rhinology, and Laryngology - March 16, 2024 Category: ENT & OMF Authors: Jessica M L Pagel Adithya Reddy Lucy Fitzgerald Mohamed Tiouririne Patrick O McGarey Daniel B Quinn James J Daniero Source Type: research

Synergistic effect of mesoporous silica nanocarrier-assisted photodynamic therapy and anticancer agent activity on lung cancer cells
This study aims to explore the combined effects of photodynamic and anticancer treatments using a multifunctional nanocarrier system co-administering the photosensitizer IR780 and the anticancer agent curcumin (Cur) on lung cancer cells. Nanocarriers were prepared by encapsulation IR780 and Cur inside polyethylene glycol-capped mesoporous silica nanoparticles (Cur&IR780@MSN). Various concentrations of nanocarriers were evaluated on A549 cells following 5  min NIR laser light (continuous wave, 785 nm, 500 mW/cm2) irradiation. The internalization of nanocarriers was observed through the fluorescence of Cur. Changes in ...
Source: Lasers in Medical Science - March 16, 2024 Category: Laser Surgery Source Type: research

Retinal complications post posterior chamber phakic intraocular lens implantation at a tertiary eye hospital in the Eastern Province of Saudi Arabia
ConclusionPatients with higher axial length and higher pre-spherical equivalent before ICL implantation are at high risk of retinal complications. (Source: International Ophthalmology)
Source: International Ophthalmology - March 16, 2024 Category: Opthalmology Source Type: research

Blue laser for the exclusive endoscopic transcanal approach to middle ear paraganglioma
ConclusionThe present study provides evidence of the safety and efficacy of endoscopic blue laser surgery, for the minimally invasive treatment of early-stage glomus tympanicum tumours. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - March 15, 2024 Category: ENT & OMF Source Type: research

Permanent occlusion of the Eustachian tube: a retrospective study on reopening procedures
This study retrospectively evaluated the efficacy and versatility of reopening procedures for the permanent occlusion of the cartilaginous Eustachian tube (POET) by analyzing four consecutive cases.MethodsThe study included all patients diagnosed with POET who suffered from Eustachian tube occlusion and glue ear. A combined approach of endoscopic transnasal/transoral laser surgery was utilized to reopen the POET. This was subsequently followed by balloon dilation (BET) and stenting for a duration of six weeks. In one distinct case, the Eustachian tube orifice was approached via a transtympanic method, where a balloon cathe...
Source: European Archives of Oto-Rhino-Laryngology - March 15, 2024 Category: ENT & OMF Source Type: research

Preoperative urine culture with contaminants is not associated with increased risk for urinary tract infection after ureteroscopic stone treatment
ConclusionThe presence of contaminants in preop-UCs is not associated with an increased risk of postop-UTIs after ureteroscopy. Our study supports that contaminants in the preop-UC can be interpreted as a negative UC in terms of postop-UTI risk stratification. Preoperative antibiotics should not be prescribed for patients undergoing uncomplicated ureteroscopy for stone surgery in the setting of a contaminated preop-UC. (Source: World Journal of Urology)
Source: World Journal of Urology - March 15, 2024 Category: Urology & Nephrology Source Type: research

Right ventricular outflow tract obstruction in twin ‐to‐twin transfusion syndrome undergoing laser surgery: A systematic review and meta‐analysis
ConclusionsRVOT occurs in about 6% of the recipient twins with TTTS, especially in stages III and IV and those with reversed ductus venosus a-wave. The findings from this systematic review support the need for a thorough cardiac assessment of pregnancies complicated by TTTS, both before and after laser, to maximize perinatal outcome, and the importance of early diagnosis of TTTS and timely management. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 14, 2024 Category: OBGYN Authors: Hiba J. Mustafa, Muhammad Jawwad, Ayesha Iqbal  Mansoor, Giorgio Pagani, Francesco D'Antonio, Asma Khalil Tags: SYSTEMATIC REVIEW Source Type: research

Outcomes of Excimer Laser Ablation Combined with Drug-coated Balloon in Atherosclerotic Lesions of the Popliteal Artery
This study aims to investigate the efficacy and safety of excimer laser ablation (ELA) combined with drug-coated balloon (DCB) for these lesions. (Source: Annals of Vascular Surgery)
Source: Annals of Vascular Surgery - March 14, 2024 Category: Surgery Authors: Xiaolang Jiang, Shuai Ju, Hao Liu, Bin Chen, Junhao Jiang, Yun Shi, Tao Ma, Changpo Lin, Gang Fang, Daqiao Guo, Xin Xu, Weiguo Fu, Zhihui Dong Tags: Clinical Research Source Type: research

WATTS happening? Evaluation of thermal dose during holmium laser lithotripsy in a high-fidelity anatomic model
ConclusionTemperature generation and thermal dose delivered are greatest closer to the tip of the laser fiber and are not dependent on power alone. Significant temperature differences were noted between four laser settings at a standardized power (40  W). Temperatures can be influenced by a variety of factors, such as laser-on time, operator duty cycle, and location in the PCS. (Source: World Journal of Urology)
Source: World Journal of Urology - March 14, 2024 Category: Urology & Nephrology Source Type: research

Color-Coded Stickers Used to Identify Appropriate Protective Eyewear in Laser Surgery
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - March 14, 2024 Category: Dermatology Authors: Matthew W. McEwen, Leonardo Marini, Anthony Benedetto Source Type: research

The role of multiple high ‐risk human papillomavirus infection on the persistence recurrence of high‐grade cervical lesions after standard treatment: A systematic review and a meta‐analysis
ConclusionsMultiple HR-HPVs infections at the time of standard treatment of HSIL entail a small but significant increased risk of persistence/recurrence of HSIL and should be taken into account in the follow-up plan. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 13, 2024 Category: OBGYN Authors: Chiara Cassani, Mattia Dominoni, Marianna Francesca Pasquali, Barbara Gardella, Arsenio Spinillo Tags: SYSTEMATIC REVIEW Source Type: research

Timing of surgery in acute deep partial-thickness burns: A study protocol
This study protocol describes a study that aims to compare long-term scar quality, clinical outcomes, and patient-reported outcomes between the treatment options. A multicentre prospective stu dy will be conducted in the three Dutch burn centres (Rotterdam, Beverwijk, and Groningen). All adult patients with acute deep-partial thickness burns, based on healing potential with Laser Doppler Imaging, are eligible for inclusion. During a nine-month baseline period, standard practice will be mo nitored. This includes conservative treatment with dressings and topical agents, and excision and grafting of residual defects if needed...
Source: PLoS One - March 11, 2024 Category: Biomedical Science Authors: Roos F. C. Salemans Source Type: research

308  nm excimer laser and tacrolimus ointment in the treatment of facial vitiligo: a systematic review and meta-analysis
This study aimed to investigate the effects and safety of 308  nm excimer laser (308 nm EL) and tacrolimus ointment (TO) in the treatment of facial vitiligo (FV). We searched Cochrane Library, PUBMED, EMBASE, CNKI, and WANGFANG from inception to June 1, 2023. Outcomes included overall response rate (ORR), total adverse reaction rate (TARR), recurrence rate a t 3-month (RR-3) and recurrence rate at 6-month (RR-6). The outcome data were presented as odds ratios (OR) with 95% confidence intervals (CI). The risk of bias was assessed by Cochrane risk-of-bias tool and data analysis was performed by RevMan 5.4 software. This st...
Source: Lasers in Medical Science - March 8, 2024 Category: Laser Surgery Source Type: research

Evaluation of combining ultrapulse CO2 with fractional CO2 laser for the treatment of atrophic scars in Asians
AbstractVarious treatment modalities have been applied to atrophic scars. Fractional CO2 laser treatment has attracted increasingly more attention because of its quicker recovery time and fewer side effects. However, its limitation of sculpting the edge is an urgent shortcoming. In order to achieve a more effective result with fewer complications, we have integrated ultrapulse CO2 and fractional CO2 lasers to for the treatment of facial atrophic scars. The study included 25 patients (10 males and 15 females) diagnosed with moderate to severe atrophic scars between August 2020 and July 2022. All subjects underwent the same ...
Source: Lasers in Medical Science - March 8, 2024 Category: Laser Surgery Source Type: research