Advancements in De Quervain Tenosynovitis Management: A Comprehensive Network Meta-Analysis
CONCLUSIONS: Corticosteroid injection with a short duration of immobilization remains the primary and effective treatment for De Quervain tenosynovitis. Extracorporeal shockwave therapy can be considered a secondary option. Alternative treatment modalities, such as isolated therapeutic injection, should be approached with caution because they did not show substantial benefits over placebo.TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic I.PMID:38613563 | DOI:10.1016/j.jhsa.2024.03.003 (Source: Hand Surgery)
Source: Hand Surgery - April 13, 2024 Category: Surgery Authors: Han Hong Chong Akhilesh Pradhan Mohit Dhingra William Liong Melinda Y T Hau Rohi Shah Source Type: research

Advancements in De Quervain Tenosynovitis Management: A Comprehensive Network Meta-Analysis
CONCLUSIONS: Corticosteroid injection with a short duration of immobilization remains the primary and effective treatment for De Quervain tenosynovitis. Extracorporeal shockwave therapy can be considered a secondary option. Alternative treatment modalities, such as isolated therapeutic injection, should be approached with caution because they did not show substantial benefits over placebo.TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic I.PMID:38613563 | DOI:10.1016/j.jhsa.2024.03.003 (Source: Hand Surgery)
Source: Hand Surgery - April 13, 2024 Category: Surgery Authors: Han Hong Chong Akhilesh Pradhan Mohit Dhingra William Liong Melinda Y T Hau Rohi Shah Source Type: research

Efficacy and safety of fractional micro-needling radiofrequency for the treatment of enlarged pores on the cheeks of a chinese cohort: a retrospective study
AbstractTo explore the efficacy and safety of fractional micro-needling radiofrequency (FMRF) in the treatment of enlarged pores on the cheek in a Chinese cohort. Patients with enlarged facial pores who underwent FMRF between January 2020 and December 2022 were included in this study. Blinded clinical assessments were performed by two independent dermatologists using a six-grade photographic enlarged pore scale and a quartile grading scale. Patients were asked to rate the degree of pain related to treatment on a visual analog scale (VAS), with scores ranging from 0 (no pain) to 10 (worst pain ever). A paired t-test was use...
Source: Lasers in Medical Science - April 13, 2024 Category: Laser Surgery Source Type: research

Novel Drug Delivery Approaches for the Localized Treatment of Cervical Cancer
AAPS PharmSciTech. 2024 Apr 11;25(4):85. doi: 10.1208/s12249-024-02801-1.ABSTRACTCervical cancer (CC) is the fourth leading cancer type in females globally. Being an ailment of the birth canal, primitive treatment strategies, including surgery, radiation, or laser therapy, bring along the risk of infertility, neonate mortality, premature parturition, etc. Systemic chemotherapy led to systemic toxicity. Therefore, delivering a smaller cargo of therapeutics to the local site is more beneficial in terms of efficacy as well as safety. Due to the regeneration of cervicovaginal mucus, conventional dosage forms come with the limi...
Source: AAPS PharmSciTech - April 11, 2024 Category: Drugs & Pharmacology Authors: Ivy Saha Jitu Halder Tushar Kanti Rajwar Ritu Mahanty Deepak Pradhan Priyanka Dash Chandan Das Vineet Kumar Rai Biswakanth Kar Goutam Ghosh Goutam Rath Source Type: research

Novel Drug Delivery Approaches for the Localized Treatment of Cervical Cancer
AAPS PharmSciTech. 2024 Apr 11;25(4):85. doi: 10.1208/s12249-024-02801-1.ABSTRACTCervical cancer (CC) is the fourth leading cancer type in females globally. Being an ailment of the birth canal, primitive treatment strategies, including surgery, radiation, or laser therapy, bring along the risk of infertility, neonate mortality, premature parturition, etc. Systemic chemotherapy led to systemic toxicity. Therefore, delivering a smaller cargo of therapeutics to the local site is more beneficial in terms of efficacy as well as safety. Due to the regeneration of cervicovaginal mucus, conventional dosage forms come with the limi...
Source: AAPS PharmSciTech - April 11, 2024 Category: Drugs & Pharmacology Authors: Ivy Saha Jitu Halder Tushar Kanti Rajwar Ritu Mahanty Deepak Pradhan Priyanka Dash Chandan Das Vineet Kumar Rai Biswakanth Kar Goutam Ghosh Goutam Rath Source Type: research

Novel Drug Delivery Approaches for the Localized Treatment of Cervical Cancer
AAPS PharmSciTech. 2024 Apr 11;25(4):85. doi: 10.1208/s12249-024-02801-1.ABSTRACTCervical cancer (CC) is the fourth leading cancer type in females globally. Being an ailment of the birth canal, primitive treatment strategies, including surgery, radiation, or laser therapy, bring along the risk of infertility, neonate mortality, premature parturition, etc. Systemic chemotherapy led to systemic toxicity. Therefore, delivering a smaller cargo of therapeutics to the local site is more beneficial in terms of efficacy as well as safety. Due to the regeneration of cervicovaginal mucus, conventional dosage forms come with the limi...
Source: AAPS PharmSciTech - April 11, 2024 Category: Drugs & Pharmacology Authors: Ivy Saha Jitu Halder Tushar Kanti Rajwar Ritu Mahanty Deepak Pradhan Priyanka Dash Chandan Das Vineet Kumar Rai Biswakanth Kar Goutam Ghosh Goutam Rath Source Type: research

Novel Drug Delivery Approaches for the Localized Treatment of Cervical Cancer
AAPS PharmSciTech. 2024 Apr 11;25(4):85. doi: 10.1208/s12249-024-02801-1.ABSTRACTCervical cancer (CC) is the fourth leading cancer type in females globally. Being an ailment of the birth canal, primitive treatment strategies, including surgery, radiation, or laser therapy, bring along the risk of infertility, neonate mortality, premature parturition, etc. Systemic chemotherapy led to systemic toxicity. Therefore, delivering a smaller cargo of therapeutics to the local site is more beneficial in terms of efficacy as well as safety. Due to the regeneration of cervicovaginal mucus, conventional dosage forms come with the limi...
Source: AAPS PharmSciTech - April 11, 2024 Category: Drugs & Pharmacology Authors: Ivy Saha Jitu Halder Tushar Kanti Rajwar Ritu Mahanty Deepak Pradhan Priyanka Dash Chandan Das Vineet Kumar Rai Biswakanth Kar Goutam Ghosh Goutam Rath Source Type: research

Novel Drug Delivery Approaches for the Localized Treatment of Cervical Cancer
AAPS PharmSciTech. 2024 Apr 11;25(4):85. doi: 10.1208/s12249-024-02801-1.ABSTRACTCervical cancer (CC) is the fourth leading cancer type in females globally. Being an ailment of the birth canal, primitive treatment strategies, including surgery, radiation, or laser therapy, bring along the risk of infertility, neonate mortality, premature parturition, etc. Systemic chemotherapy led to systemic toxicity. Therefore, delivering a smaller cargo of therapeutics to the local site is more beneficial in terms of efficacy as well as safety. Due to the regeneration of cervicovaginal mucus, conventional dosage forms come with the limi...
Source: AAPS PharmSciTech - April 11, 2024 Category: Drugs & Pharmacology Authors: Ivy Saha Jitu Halder Tushar Kanti Rajwar Ritu Mahanty Deepak Pradhan Priyanka Dash Chandan Das Vineet Kumar Rai Biswakanth Kar Goutam Ghosh Goutam Rath Source Type: research

Novel Drug Delivery Approaches for the Localized Treatment of Cervical Cancer
AAPS PharmSciTech. 2024 Apr 11;25(4):85. doi: 10.1208/s12249-024-02801-1.ABSTRACTCervical cancer (CC) is the fourth leading cancer type in females globally. Being an ailment of the birth canal, primitive treatment strategies, including surgery, radiation, or laser therapy, bring along the risk of infertility, neonate mortality, premature parturition, etc. Systemic chemotherapy led to systemic toxicity. Therefore, delivering a smaller cargo of therapeutics to the local site is more beneficial in terms of efficacy as well as safety. Due to the regeneration of cervicovaginal mucus, conventional dosage forms come with the limi...
Source: AAPS PharmSciTech - April 11, 2024 Category: Drugs & Pharmacology Authors: Ivy Saha Jitu Halder Tushar Kanti Rajwar Ritu Mahanty Deepak Pradhan Priyanka Dash Chandan Das Vineet Kumar Rai Biswakanth Kar Goutam Ghosh Goutam Rath Source Type: research

Spectroscopic evaluation of sesame and mustard oils treated with Murchana method
This study focusses on the spectroscopic analysis of sesame and mustard oils prepared using the ayurvedic processing method ‘Murchana’. Spectroscopic analysis techniques including UV-Vis absorbance spectroscopy, fluorescence spectroscopy, and FTIR spectroscopy were employed to study the oils. Origin software was used to plot graphs of the spectra. The result s indicated that themurchana process may reduce the components of the oil responsible for its oxidation, thereby increasing the shelf life of the oils. However, further investigations, including other spectroscopy and chromatography techniques, will prove beneficia...
Source: Lasers in Medical Science - April 11, 2024 Category: Laser Surgery Source Type: research

Experience with 808-nm diode laser in the treatment of 47 cases of oral vascular anomalies
Braz Oral Res. 2024 Apr 5;38:e025. doi: 10.1590/1807-3107bor-2024.vol38.0025. eCollection 2024.ABSTRACTTreatment of oral vascular anomalies (OVA) has focused on minimally invasive techniques rather than radical surgery. We investigated the efficacy and safety of diode laser using the photocoagulation technique in the management of OVA. Forty-seven subjects with OVA were treated with forced dehydration with induced photocoagulation (FDIP) using diode laser (808 nm/4.5 W). This series consisted mostly of male (63.8%) and non-white (63.8%) patients with a mean age of 57.4 years. Varices (91.5%), venous malformations (6.4%), a...
Source: Cell Research - April 10, 2024 Category: Cytology Authors: Fernanda Vieira Heimlich Jos é Alcides Almeida de Arruda Camila de Nazar é Alves de Oliveira Kato Leni Ver ônica de Oliveira Silva Leandro Napier Souza Marcus Vinicius Lucas Ferreira Jo ão de Jesus Viana Pinheiro Tarc ília Aparecida Silva Lucas Guima Source Type: research

FF-ViT: probe orientation regression for robot-assisted endomicroscopy tissue scanning
ConclusionThe performance evaluation study verifies the clinical value of the proposed framework and its potential to be integrated into surgical robotic platforms for intraoperative tissue scanning. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - April 10, 2024 Category: Intensive Care Source Type: research

The use of lens anterior capsule disc for corneal endothelium protection during femtosecond laser-assisted cataract surgery in eyes with low endothelial cell density
Adv Ophthalmol Pract Res. 2024 Feb 28;4(2):65-68. doi: 10.1016/j.aopr.2024.02.002. eCollection 2024 May-Jun.NO ABSTRACTPMID:38590554 | PMC:PMC10999371 | DOI:10.1016/j.aopr.2024.02.002 (Source: Cell Research)
Source: Cell Research - April 9, 2024 Category: Cytology Authors: Nina Asrini Noor Johan Hutauruk Tjahjono D Gondhowiardjo Source Type: research

Combination Administration of Heparin and Nitroglycerin for the Treatment of Polycaprolactone-Induced Intravascular Embolism: A Preclinical Investigation
ConclusionsThe combination of heparin and nitroglycerin effectively restores blood flow reperfusion in the intravascular embolization caused by PCL filler injection, alleviates local tissue edema and flap necrosis. These findings offer a novel approach for future clinical management of intravascular embolization with PCL-containing filler injection.No Level AssignedThis journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, a...
Source: Aesthetic Plastic Surgery - April 9, 2024 Category: Cosmetic Surgery Source Type: research