Differences in femoral fracture localizations in men and women in Switzerland between 1998 and 2021 —reversal of the secular trend?
ConclusionIncidence changes of pertrochanteric fractures and femoral shaft fractures deserve increased attention, especially in men. Pooling diagnostic codes for defining hip fractures may hide differing patterns by localization and sex. (Source: Osteoporosis International)
Source: Osteoporosis International - February 24, 2024 Category: Orthopaedics Source Type: research
Twelve-month resistance and impact exercise program or risedronate provides a relative benefit to hip bone structure in postmenopausal women: results from a randomized controlled trial
ConclusionExercise and bisphosphonates may influence structural and strength estimates at the hip, but not at peripheral sites (tibia). Neither exercise nor bisphosphonates were found to be superior in improving estimates of hip bone strength. (Source: Osteoporosis International)
Source: Osteoporosis International - February 17, 2024 Category: Orthopaedics Source Type: research
Hypophosphatasia diagnosis: current state of the art and proposed diagnostic criteria for children and adults
ConclusionFollowing consensus meetings, agreement was reached regarding the major and minor criteria that can assist in establishing a clinical diagnosis of HPP in adults and children. (Source: Osteoporosis International)
Source: Osteoporosis International - February 15, 2024 Category: Orthopaedics Source Type: research
Radiomorphometric indices of the mandible as indicators of decreased bone mineral density and osteoporosis – meta-analysis and systematic review
AbstractThis review aims to evaluate the accuracy of various mandibular radiomorphometric indices in comparison with DEXA BMD measurements in the diagnosis of osteopenia and osteoporosis based on a meta-analysis of the sensitivity and specificity of the indices. PRISMA statement was followed. The materials for analysis were collected in August 2023 by searching three databases: PubMed Central, Web of Science, and Scopus. The selection of studies consisted of three selection stages, and 64 articles were finally obtained. Quality assessment was performed with the QUADAS-2 tool, and the general methodological quality of retri...
Source: Osteoporosis International - February 15, 2024 Category: Orthopaedics Source Type: research
Isoflavone intervention and its impact on bone mineral density in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials
ConclusionThis systematic review and meta-analysis suggests that isoflavone interventions, especially those containing genistein of at least 50 mg/day, can effectively enhance BMD in postmenopausal women. (Source: Osteoporosis International)
Source: Osteoporosis International - February 15, 2024 Category: Orthopaedics Source Type: research
The challenge of hypophosphatasia diagnosis in adults: results from the HPP International Working Group Literature Surveillance
AbstractHypophosphatasia (HPP) is an inborn error of metabolism caused by reduced or absent activity of the tissue non-specific alkaline phosphatase (TNSALP) enzyme, resulting from pathogenic variants in theALPL gene. Clinical presentation of HPP is highly variable, including lethal and severe forms in neonates and infants, a benign perinatal form, mild forms manifesting in adulthood, and odonto-HPP. Diagnosis of HPP remains a challenge in adults, as signs and symptoms may be mild and non-specific. Disease presentation varies widely; there are no universal signs or symptoms, and the disease often remains underdiagnosed or ...
Source: Osteoporosis International - February 15, 2024 Category: Orthopaedics Source Type: research
CT image-based biomarkers for opportunistic screening of osteoporotic fractures: a systematic review and meta-analysis
AbstractThe use of opportunistic computed tomography (CT) image-based biomarkers may be a low-cost strategy for screening older individuals at high risk for osteoporotic fractures and populations that are not sufficiently targeted. This review aimed to assess the discriminative ability of image-based biomarkers derived from existing clinical routine CT scans for hip, vertebral, and major osteoporotic fracture prediction. A systematic search in PubMed MEDLINE, Embase, Cochrane, and Web of Science was conducted from the earliest indexing date until July 2023. The evaluation of study quality was carried out using a modified Q...
Source: Osteoporosis International - February 14, 2024 Category: Orthopaedics Source Type: research
Prunes preserve cortical density and estimated strength of the tibia in a 12-month randomized controlled trial in postmenopausal women: The Prune Study
ConclusionPrune consumption for 12 months preserved cortical bone structure and estimated bone strength at the weight-bearing tibia in postmenopausal women. (Source: Osteoporosis International)
Source: Osteoporosis International - February 13, 2024 Category: Orthopaedics Source Type: research
Physical performance and sarcopenia assessment in patients with a recent fracture visiting the Fracture Liaison Service
ConclusionsPhysical performance is significantly lower in FLS patients compared to healthy peers, especially in patients with hip, major or prevalent VF. These findings underline the need to assess and improve the physical performance of FLS patients, despite a low prevalence of sarcopenia. (Source: Osteoporosis International)
Source: Osteoporosis International - February 13, 2024 Category: Orthopaedics Source Type: research
Prunes preserve cortical density and estimated strength of the tibia in a 12-month randomized controlled trial in postmenopausal women: The Prune Study
ConclusionPrune consumption for 12 months preserved cortical bone structure and estimated bone strength at the weight-bearing tibia in postmenopausal women. (Source: Osteoporosis International)
Source: Osteoporosis International - February 13, 2024 Category: Orthopaedics Source Type: research
Physical performance and sarcopenia assessment in patients with a recent fracture visiting the Fracture Liaison Service
ConclusionsPhysical performance is significantly lower in FLS patients compared to healthy peers, especially in patients with hip, major or prevalent VF. These findings underline the need to assess and improve the physical performance of FLS patients, despite a low prevalence of sarcopenia. (Source: Osteoporosis International)
Source: Osteoporosis International - February 13, 2024 Category: Orthopaedics Source Type: research
Correction: Different bone health progression patterns and early-stage risk marker in glucocorticoid-treated ambulatory Duchenne muscular dystrophy
(Source: Osteoporosis International)
Source: Osteoporosis International - February 6, 2024 Category: Orthopaedics Source Type: research
