Evaluation of mobility recovery after hip fracture: a scoping review of randomized controlled studies
AbstractFew older adults regain their pre-fracture mobility after a hip fracture. Intervention studies evaluating effects on gait typically use short clinical tests or in-lab parameters that are often limited to gait speed only. Measurements of mobility in daily life settings exist and should be considered to a greater extent than today. Less than half of hip fracture patients regain their pre-fracture mobility. Mobility recovery is closely linked to health status and quality of life, but there is no comprehensive overview of how gait has been evaluated in intervention studies on hip fracture patients. The purpose was to i...
Source: Osteoporosis International - October 6, 2023 Category: Orthopaedics Source Type: research

Improvement of proportion of days covered for denosumab under implementation of clinical pharmacist adherence management system: normal and COVID-19 period
ConclusionsClinical pharmacist-led CPAMS could effectively improve adherence to denosumab and the treatment of osteoporosis. (Source: Osteoporosis International)
Source: Osteoporosis International - October 6, 2023 Category: Orthopaedics Source Type: research

The comparison of alendronate and raloxifene after denosumab (CARD) study: A comparative efficacy trial
ConclusionsThese results suggest that after one year of denosumab, one year of alendronate is better able to maintain the inhibition of bone remodeling and BMD gains than raloxifene. (Source: Osteoporosis International)
Source: Osteoporosis International - October 6, 2023 Category: Orthopaedics Source Type: research

Cost-effectiveness analysis of fracture liaison services: a Markov model using Dutch real-world data
ConclusionThis study provides the first health-economic analysis of FLS in the Netherlands, suggesting the implementation of FLS could lead to lifetime health-economic benefits. (Source: Osteoporosis International)
Source: Osteoporosis International - October 3, 2023 Category: Orthopaedics Source Type: research

The relationship between length of denosumab treatment for postmenopausal osteoporosis and serum TRAcP5b measured six months after the last injection
ConclusionOur observations indicate that serum TRAcP5b, measured at 6  months after a Dmab injection, is not a useful early marker for time-dependent increased accumulation of osteoclasts in humans and for identification of patients at risk for a higher rebound increase in bone resorption. (Source: Osteoporosis International)
Source: Osteoporosis International - October 2, 2023 Category: Orthopaedics Source Type: research

A promising strategy for the diagnosis, treatment, and prevention of osteoporosis (EMS strategy)
(Source: Osteoporosis International)
Source: Osteoporosis International - September 22, 2023 Category: Orthopaedics Source Type: research

Correction to: Denosumab-related osteonecrosis of the jaw after tooth extraction and the effects of a short drug holiday in cancer patients: a multicenter retrospective study
(Source: Osteoporosis International)
Source: Osteoporosis International - September 20, 2023 Category: Orthopaedics Source Type: research

Effect of denosumab on bone mineral density in a postmenopausal osteoporotic woman with prolonged chronic mild hyponatremia
(Source: Osteoporosis International)
Source: Osteoporosis International - September 19, 2023 Category: Orthopaedics Source Type: research

Screening and management of osteoporosis: a survey of knowledge, attitude, and practice among healthcare professionals in Egypt —a study by the Egyptian Academy of Bone Health
ConclusionsThis work has identified some of the barriers to implementing guidelines for osteoporosis and fragility fracture management. In the meantime, it highlights the urgency of intensifying efforts to develop the knowledge and attitude of the healthcare professionals dealing with this condition in Egypt. (Source: Osteoporosis International)
Source: Osteoporosis International - September 18, 2023 Category: Orthopaedics Source Type: research

Determining patient preferences for the medical management of osteoporosis using conjoint analysis
ConclusionsWhile about 60% of patients prioritized efficacy when selecting an osteoporosis therapy, the remaining 40% valued other factors more highly. Furthermore, individual patient characteristics and clinical factors did not reliably predict patient decision making, suggesting that development and implementation of shared decision-making tools is warranted. (Source: Osteoporosis International)
Source: Osteoporosis International - September 18, 2023 Category: Orthopaedics Source Type: research

Global burden of hip fracture: The Global Burden of Disease Study
ConclusionsThe incidence and the number of hip fractures among patients aged 55 years and older increased over the past three decades, indicating that the global burden of hip fracture is still large. Hip fractures among males are perhaps underestimated, and older adults should be given more attention. (Source: Osteoporosis International)
Source: Osteoporosis International - September 14, 2023 Category: Orthopaedics Source Type: research

Association of prior treatment with nitrogen-containing bisphosphonates on outcomes of COVID-19 positive patients
ConclusionAmong older COVID-19 patients, prior exposure to N-BP including ZOL was not associated with a reduction in ICU admission, ventilator use, or death. (Source: Osteoporosis International)
Source: Osteoporosis International - September 13, 2023 Category: Orthopaedics Source Type: research