Worldwide prevalence and incidence of osteoporotic vertebral fractures
AbstractWe investigated the prevalence and incidence of vertebral fractures worldwide. We used a systematic Medline search current to 2015 and updated as per authors ’ libraries. A total of 62 articles of fair to good quality and comparable methods for vertebral fracture identification were considered. The prevalence of morphometric vertebral fractures in European women is highest in Scandinavia (26%) and lowest in Eastern Europe (18%). Prevalence rates in Nor th America (NA) for White women ≥50 are 20–24%, with a White/Black ratio of 1.6. Rates in women ≥50 years in Latin America are overall lower t...
Source: Osteoporosis International - February 6, 2017 Category: Orthopaedics Source Type: research

Low-trauma fractures without osteoporosis
AbstractIn clinical practice, areal bone mineral density (aBMD) is usually measured using dual-energy X-ray absorptiometry (DXA) to assess bone status in patients with or without osteoporotic fracture. As BMD has a Gaussian distribution, it is difficult to define a cutoff for osteoporosis diagnosis. Based on epidemiological considerations, WHO defined a DXA-based osteoporosis diagnosis with a T-score
Source: Osteoporosis International - February 4, 2017 Category: Orthopaedics Source Type: research

Effect of comorbidities on the association between age and hospital mortality after fall-related hip fracture in elderly patients
ConclusionsThe association between age and mortality after hip fracture remains after adjusting for numerous comorbidities. However, some potentially controllable disorders are associated with an increased risk for mortality, thus, improving their management could benefit survival. (Source: Osteoporosis International)
Source: Osteoporosis International - February 3, 2017 Category: Orthopaedics Source Type: research

Validity of height loss as a predictor for prevalent vertebral fractures, low bone mineral density, and vitamin D deficiency
ConclusionsThis study demonstrated that prospective height loss is an effective tool to identify patients with vertebral fractures, low bone mineral density, and vitamin D deficiency although a lack of height loss does not rule out these diagnoses. If significant height loss is present, the high positive likelihood ratios support a further workup. (Source: Osteoporosis International)
Source: Osteoporosis International - February 3, 2017 Category: Orthopaedics Source Type: research

The association between sarcopenia and functional outcomes among older patients with hip fracture undergoing in-hospital rehabilitation
This study evaluates the prevalence of sarcopenia among older people admitted to a rehabilitation unit after hip fracture and the association between sarcopenia and functional outcomes. The results show that sarcopenia had a negative impact on functional recovery. The assessment of sarcopenia among older adults receiving rehabilitation programs is crucial.IntroductionSarcopenia is a highly prevalent geriatric syndrome associated with adverse outcomes, including falls, disability, institutionalization, and mortality. Few studies assessed sarcopenia among older adults receiving rehabilitation programs.MethodsPatients aged 70...
Source: Osteoporosis International - February 2, 2017 Category: Orthopaedics Source Type: research

Bone mass loss is associated with systolic blood pressure in postmenopausal women with type 2 diabetes in Tibet: a retrospective cross-sectional study
ConclusionsAmong diabetic postmenopausal women dwelling in high altitude, 27.3% patients have osteoporosis, 42.4% patients have osteopenia, and 30.3% are normal. The BMD T-score of spine was inversely associated with SBP and positively associated with HbA1c, while the BMD T-score of femoral neck or hip was inversely associated with ages and SBP. (Source: Osteoporosis International)
Source: Osteoporosis International - February 2, 2017 Category: Orthopaedics Source Type: research

Association of DPP-4 activity with BMD, body composition, and incident hip fracture: the Cardiovascular Health Study
ConclusionPlasma DPP-4 activity, within the endogenous physiological range, was significantly associated with race, but not with BMD, body composition, or incident hip fractures in elderly community-dwelling subjects. (Source: Osteoporosis International)
Source: Osteoporosis International - February 2, 2017 Category: Orthopaedics Source Type: research

The time to and determinants of first fractures in boys with Duchenne muscular dystrophy
This study was a retrospective longitudinal study of 30 boys with DMD
Source: Osteoporosis International - January 28, 2017 Category: Orthopaedics Source Type: research

Evaluation on the cost-effective threshold of osteoporosis treatment on elderly women in China using discrete event simulation model
ConclusionsThe current study provides evidence that osteoporosis treatment is cost-effective among a subpopulation of Chinese senior women. The results also indicate that the cost-effectiveness of using osteoporosis treatment is sensitive to the WTP threshold and annual treatment costs. (Source: Osteoporosis International)
Source: Osteoporosis International - January 27, 2017 Category: Orthopaedics Source Type: research

Biologic therapies and bone loss in rheumatoid arthritis
AbstractIntroductionRheumatoid arthritis (RA) is a common systemic autoimmune disease of unknown cause, characterized by a chronic, symmetric, and progressive inflammatory polyarthritis. One of the most deleterious effects induced by the chronic inflammation of RA is bone loss. During the last 15 years, the better knowledge of the cytokine network involved in RA allowed the development of potent inhibitors of the inflammatory process classified as biological DMARDs. These new drugs are very effective in the inhibition of inflammation, but there are only few studies regarding their role in bone protection. The principal aim...
Source: Osteoporosis International - January 27, 2017 Category: Orthopaedics Source Type: research

The role of calcium supplementation in healthy musculoskeletal ageing
In conclusion, we recommend, on the basis of the current evidence, that calcium supplementation, with concomitant vitamin D supplementation, is supported for patients at high risk of calcium and vitamin D insufficiency, and in those who are receiving treatment for osteoporosis. (Source: Osteoporosis International)
Source: Osteoporosis International - January 27, 2017 Category: Orthopaedics Source Type: research

A model-based cost-effectiveness analysis of osteoporosis screening and treatment strategy for postmenopausal Japanese women
ConclusionsIn conclusion, dual energy X-ray absorptiometry (DXA) screening and alendronate therapy for osteoporosis would be cost-effective for postmenopausal Japanese women over 60  years. In terms of cost-effectiveness, the individual need for osteoporosis screening should be determined by age and clinical risk factors. (Source: Osteoporosis International)
Source: Osteoporosis International - January 27, 2017 Category: Orthopaedics Source Type: research

Meagre effects of disuse on the human fibula are not explained by bone size or geometry
AbstractSummaryFibula response to disuse is unknown; we assessed fibula bone in spinal cord injury (SCI) patients and able-bodied counterparts. Group differences were smaller than in the neighbouring tibia which could not be explained by bone geometry. Differential adaptation of the shank bones may indicate previously unknown mechanoadaptive behaviours of bone.IntroductionThe fibula supports only a small and highly variable proportion of shank compressive load ( −8 to +19 %), and little is known about other kinds of stresses. Hence, whilst effects of habitual loading on tibia are well-known, fibula response to d...
Source: Osteoporosis International - January 27, 2017 Category: Orthopaedics Source Type: research

Bone mineral density and microarchitecture in patients with essential thrombocythemia and polycythemia vera
ConclusionThese results reveal no evidence of secondary osteoporosis among patients with ET or PV. The mechanism behind the increased fracture risk in ET or PV patients remains unknown. (Source: Osteoporosis International)
Source: Osteoporosis International - January 27, 2017 Category: Orthopaedics Source Type: research

Time course of osteoporotic vertebral fractures by magnetic resonance imaging using a simple classification: a multicenter prospective cohort study
ConclusionsMRI signal changes were associated with the compression degree and angular motion of fractured vertebrae. This classification showed sufficient reliability in categorizing MRI findings of OVFs. (Source: Osteoporosis International)
Source: Osteoporosis International - January 27, 2017 Category: Orthopaedics Source Type: research

A meta-analysis of breastfeeding and osteoporotic fracture risk in the females
ConclusionsOur meta-analysis revealed that breastfeeding may well reduce the risk of osteoporotic fracture. More cohort studies with large sample sizes are needed to confirm the conclusion. (Source: Osteoporosis International)
Source: Osteoporosis International - January 27, 2017 Category: Orthopaedics Source Type: research

Adipokines may mediate the relationship between resting metabolic rates and bone mineral densities in obese women
AbstractSummaryThe researchers sought to test the possible link between resting metabolic rate and bone mineral density through four adipokines. Participants with lower resting metabolic rate (RMR) per kilogram demonstrated higher total bone mineral density (BMD), total T-score, and total Z-score. Omentin-1 had a mediatory effect on the relationship between RMR/kg of body weight and bone parameters.IntroductionThe previous results of studies regarding the links between obesity and bone health are controversial. For this reason, the researchers sought to test the possible link between RMR and BMD through the following four ...
Source: Osteoporosis International - January 23, 2017 Category: Orthopaedics Source Type: research

Opportunistic screening for osteoporosis by routine CT in Southern Europe
AbstractSummaryFeasibility evaluation of early detection of osteoporosis in oncologic patients by bone mineral density (BMD) on abdominal computed tomography (CT) scans performed for other clinical indications, by using dual-energy X-ray absorptiometry (DXA) as reference. Abdominal CT images can identify patients with osteoporosis BMD without additional radiation exposure or cost.IntroductionThe purpose of the study is to evaluate the feasibility of early detection of osteoporosis by bone mineral density (BMD) on abdominal computed tomography (CT) scans performed in oncologic patients, comparing calibrated and uncalibrated...
Source: Osteoporosis International - January 20, 2017 Category: Orthopaedics Source Type: research

Association between sleep apnea and low bone mass in adults: a systematic review and meta-analysis
ConclusionsAn association between sleep apnea and low bone mass in adults is plausible, but supporting evidence has a risk of bias and is inconsistent. (Source: Osteoporosis International)
Source: Osteoporosis International - January 18, 2017 Category: Orthopaedics Source Type: research

Treatment of Ribbing disease with 5-year follow-up and literature review
AbstractRibbing disease, or multiple diaphyseal sclerosis, is a rare diaphyseal sclerosis of unknown etiology. Patients with this pathology usually present with asymmetric pain limited to the lower extremities. Though all efforts are made to relieve the progressive pain associated with Ribbing disease, no medical or surgical treatments have been established yet. In this case report, we followed up a Ribbing case with sclerotic bone fenestration for 5  years. The radiological changes and the clinical effects are described, and the different Ribbing treatments are then briefly reviewed. (Source: Osteoporosis International)
Source: Osteoporosis International - January 18, 2017 Category: Orthopaedics Source Type: research

Dietary potassium intake is beneficial to bone health in a low calcium intake population: the Korean National Health and Nutrition Examination Survey (KNHANES) (2008 –2011)
ConclusionsDietary potassium intake was positively associated with BMD in men aged>50  years and postmenopausal women, indicating the beneficial effects of dietary potassium intake on bone health. (Source: Osteoporosis International)
Source: Osteoporosis International - January 16, 2017 Category: Orthopaedics Source Type: research

International Osteoporosis Foundation and European Calcified Tissue Society Working Group. Recommendations for the screening of adherence to oral bisphosphonates
ConclusionsIf a significant decrease is observed, the treatment can continue, but if no decrease occurs, the clinician should reassess to identify problems with the treatment, mainly low adherence. (Source: Osteoporosis International)
Source: Osteoporosis International - January 16, 2017 Category: Orthopaedics Source Type: research

The prevalence of osteoporosis and the rate of bone loss in Korean adults: the Chungju metabolic disease cohort (CMC) study
ConclusionsA substantial number of subjects had osteoporosis, even though we standardized the prevalence of osteoporosis. In total hip, the mean BMD was decreased during the follow-up period; in addition, the annual percentage loss increased with age. However, spine BMD remained approximately stable or increased over time and therefore may not be appropriate for assessing BMD change. (Source: Osteoporosis International)
Source: Osteoporosis International - January 12, 2017 Category: Orthopaedics Source Type: research

The relationship between vitamin D status and muscle strength in young healthy adults from sunny climate countries currently living in the northeast of Scotland
ConclusionsThis study suggests that vitamin D may be important for muscle health in young adults migrating from sunnier climates to high latitudes, yet the potential effect is small. (Source: Osteoporosis International)
Source: Osteoporosis International - January 12, 2017 Category: Orthopaedics Source Type: research

Use of antipsychotics increases the risk of fracture: a systematic review and meta-analysis
ConclusionsFGA users were at a higher risk of hip fracture than SGA users. Both FGAs and SGAs were associated with an increased risk of fractures, especially among the older population. Therefore, the benefit of the off-label use of antipsychotics in elderly patients should be weighed against any risks for fracture. (Source: Osteoporosis International)
Source: Osteoporosis International - January 12, 2017 Category: Orthopaedics Source Type: research

Long-term effect of aromatase inhibitors on bone microarchitecture and macroarchitecture in non-osteoporotic postmenopausal women with breast cancer
AbstractSummaryIn non-osteoporotic postmenopausal women with breast cancer, aromatase inhibitors (AIs) negatively affected bone mineral density (BMD), lumbar spine trabecular bone score (TBS) as a bone microarchitecture index, and hip geometry as a bone macroarchitecture index.IntroductionAIs increase the risk of fracture in patients with breast cancer. Therefore, we aimed to evaluate the long-term skeletal effects of AIs in postmenopausal women with primary breast cancer.MethodsWe performed a retrospective longitudinal observational study in non-osteoporotic patients with breast cancer who were treated with AIs for ≥3&...
Source: Osteoporosis International - January 12, 2017 Category: Orthopaedics Source Type: research

Use of proton pump inhibitors and mortality after hip fracture in a nationwide study
AbstractSummaryWe analyzed the association of proton pump inhibitors (PPIs) with mortality after osteoporosis-related hip fracture in Austria. PPIs were associated with reduced 90-day mortality but elevated mortality after half a year when initiated pre-fracture. Inpatients and discharged patients on PPIs showed lowered in-hospital and 90-day mortality, respectively.IntroductionWe herein investigated use of proton pump inhibitors (PPIs) and mortality among hip fracture patients in a nationwide study in Austria.MethodsIn this retrospective cohort study, data on use of PPIs were obtained from 31,668 Austrian patients ≥50&...
Source: Osteoporosis International - January 12, 2017 Category: Orthopaedics Source Type: research

Cortical porosity exhibits accelerated rate of change in peri- compared with post-menopausal women
ConclusionThis is a 6-year prospective HR-pQCT study exploring rate of change in Caucasian peri- and post-menopausal women. The microarchitectural features represented by Ct.Po and Tt.Ar changed at a significantly different rate between groups, but group differences were not detected by density measures. (Source: Osteoporosis International)
Source: Osteoporosis International - January 10, 2017 Category: Orthopaedics Source Type: research

Protein intake and risk of hip fractures in postmenopausal women and men age 50 and older
ConclusionWe found no evidence that higher protein intake increases risk of hip fracture in these Caucasian men and women. Protein intake from specific sources was inversely associated with risk, but these associations appeared to differ by gender. (Source: Osteoporosis International)
Source: Osteoporosis International - January 10, 2017 Category: Orthopaedics Source Type: research

Hyponatremia and fractures: should hyponatremia be further studied as a potential biochemical risk factor to be included in FRAX algorithms?
AbstractThe Fracture Risk Assessment Tool (FRAX ®) was developed by the WHO Collaborating Centre for metabolic bone diseases to evaluate fracture risk of patients. It is based on patient models that integrate the risk associated with clinical variables and bone mineral density (BMD) at the femoral neck. The clinical risk factors included in FRAX were chosen to include only well-established and independent variables related to skeletal fracture risk. The FRAX tool has acquired worldwide acceptance despite having several limitations. FRAX models have not included biochemical derangements in estimation of fracture risk du...
Source: Osteoporosis International - January 10, 2017 Category: Orthopaedics Source Type: research

High dietary sodium intake is associated with low bone mass in postmenopausal women: Korea National Health and Nutrition Examination Survey, 2008 –2011
ConclusionsThe present study suggested that high sodium intake could be a potential risk factor for low bone mass after adjusting for confounding factors in postmenopausal women. (Source: Osteoporosis International)
Source: Osteoporosis International - January 10, 2017 Category: Orthopaedics Source Type: research

Pregnancy-associated osteoporosis: a case-control study
AbstractSummaryThe etiology and underlying mechanisms of pregnancy-associated osteoporosis (PAO) are still unknown, since no systematic analyses exist. Our results indicate that PAO is a heterogeneous, rare but severe disease including a substantial number of fractures with a significant delay from first symptom to diagnose.IntroductionPregnancy-associated osteoporosis (PAO) is a rare but severe type of premenopausal osteoporosis. Most common symptom includes acute lower back pain due to vertebral fracture predominantly occurring in the last trimester of pregnancy or immediately postpartum. The exact underlining mechanisms...
Source: Osteoporosis International - January 10, 2017 Category: Orthopaedics Source Type: research

Frequency of discontinuation of injectable osteoporosis therapies in US patients over 2  years
ConclusionsThe majority of US patients discontinue injectable osteoporosis treatment by the end of the first year following initiation. (Source: Osteoporosis International)
Source: Osteoporosis International - January 5, 2017 Category: Orthopaedics Source Type: research

Understanding fragility fracture patients ’ decision-making process regarding bisphosphonate treatment
ConclusionsThe processes and reasoning related to persisting with or stopping OP treatments post-fracture are complex and dynamic. Our findings suggest two areas of leverage for healthcare providers to reinforce to improve persistence: (1) the severity and risks and harms related to untreated clinical OP and (2) the favorable benefit-to-risk profile for OP treatments. (Source: Osteoporosis International)
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Telementoring: a novel approach to reducing the osteoporosis treatment gap
ConclusionsBone Health ECHO telementors healthcare professionals in underserved areas to provide advanced levels of care for patients with skeletal disorders. The experience of Bone Health ECHO will guide the development of similar telementoring clinics in other locations. More data are needed to fully evaluate this novel approach to reducing the osteoporosis treatment gap. (Source: Osteoporosis International)
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

The levels of bone turnover markers 25(OH)D and PTH and their relationship with bone mineral density in postmenopausal women in a suburban district in China
This study evaluated the levels of bone turnover markers (BTMs) and investigated relationships between them and bone mineral density (BMD) in postmenopausal women in China suburban district. The prevalence of osteoporosis was 25.03  % at lumbar spine and 6.23 % at femoral neck, and BTMs were negatively correlated with BMDs.IntroductionThe aims of this study were to evaluate the levels of bone turnover markers (BTMs), including serum N-terminal procollagen of type I collagen (P1NP), beta C-terminal cross-linked of type I collagen ( β-CTX), 25-hydroxyvitamin D [25(OH)D], and parathyroid hormone (PTH), and to i...
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Sensitivity and specificity of radiographic characteristics in atypical femoral fractures
ConclusionLateral cortex transverse fracture pattern was the most sensitive and specific characteristic and the most highly agreed upon across reviewers. Other characteristics were less readily agreed upon across reviewers. Measurement of discrete combinations of individual characteristics may enhance sensitivity and/or specificity. (Source: Osteoporosis International)
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

The relationship between maternal self-efficacy, compliance and outcome in a trial of vitamin D supplementation in pregnancy
AbstractSummaryIn a randomised controlled trial of vitamin D during pregnancy, we demonstrated that women with lower self-efficacy were more likely to experience practical problems with taking the trial medication and that this was associated with lower compliance and achieved 25(OH)-vitamin D concentrations.IntroductionThe relationship between self-efficacy (the belief that one can carry out a behaviour), compliance with study protocol and outcome was explored within a randomised, double-blind, placebo-controlled trial of vitamin D supplementation in pregnancy.MethodsIn the Maternal Vitamin D Osteoporosis Study (MAVIDOS) ...
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Fracture risk in people with developmental disabilities: results of a large claims data analysis
ConclusionsPeople with DD have a high fracture burden. Comparable risks of femoral fracture, for example, occurred about 10 –15 years earlier in females and even 20–40 years earlier in males with DD than in the general population. (Source: Osteoporosis International)
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

The impact of depot medroxyprogesterone acetate on fracture risk: a case-control study from the UK
ConclusionsOur results indicate that DMPA exposure is associated with increased fracture risk and may have negative effects on bone metabolism, resulting in impaired bone mineral acquisition during adolescence and accelerated bone loss in adult life. (Source: Osteoporosis International)
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Fractures in spina bifida from childhood to young adulthood
ConclusionsThe risk of fracture is lower in adults compared with children with spina bifida. The predominant childhood fracture affects the distal femur, and immobility is the most significant risk factor for fracture. Clinical factors contributing to fracture risk need to be elucidated to enable selection of patients who require investigation and treatment of osteoporosis. (Source: Osteoporosis International)
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Factors associated with fractures in HIV-infected persons: which factors matter?
This study aims to determine what factors are associated with increased risk of fracture among patients with HIV, in particular whether an important medication used to treat HIV, tenofovir, is associated with fracture. Our study found that while co-infection with hepatitis C and markers of HIV severity were associated with fracture, tenofovir was not.IntroductionGrowing evidence suggests that tenofovir disoproxil fumarate decreases bone density among patients with HIV, but there are conflicting reports as to whether this decrease in bone density translates to higher fracture risk. We aimed to determine what factors were as...
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Acute effects of calcium supplements on blood pressure: randomised, crossover trial in postmenopausal women
AbstractSummaryCalcium supplements appear to increase cardiovascular risk, but the mechanism is unknown. We investigated the acute effects of calcium supplements on blood pressure in postmenopausal women. The reduction in systolic blood pressure was smaller after calcium compared with the placebo in the hours following dosing.IntroductionCalcium supplements appear to be associated with increased cardiovascular risk; however, the mechanism of this is uncertain. We previously reported that blood pressure declined over a day in older women, and that this reduction was smaller following a calcium supplement. To confirm this fi...
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Access to fracture risk assessment by FRAX and linked National Osteoporosis Guideline Group (NOGG) guidance in the UK —an analysis of anonymous website activity
ConclusionThe study shows that the facilitated interaction between web-based fracture risk assessment and clinical guidelines is widely used in the UK. The approach could usefully be adopted in other countries for which a FRAX model is available. (Source: Osteoporosis International)
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

S ubjects with osteoporosis to remain at high risk for fracture despite benefit of prior bisphosphonate treatment — a D anish case-control study
AbstractSummaryThe benefits of pharmaceutical treatment for osteoporosis may be limited for a number of patients, as they continue to experience fractures. Alternative treatments may be considered for subjects whom remain at high risk for future fractures.IntroductionPrevious studies have investigated the effects of good adherence to anti-osteoporosis medication. However, very few studies have described why some patients experience fractures and loss of BMD despite adherence to treatment. The aim of this study was to estimate the proportion of patients at high risk for fracture despite being compliant to bisphosphonate tre...
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Factors associated with osteoporosis in patients with chronic obstructive pulmonary disease —a nationwide retrospective study
AbstractSummaryThe present study aimed to identify the factors associated with osteoporosis in patients with chronic obstructive pulmonary disease in Taiwan. The study found that female sex, old age, and use of a high dose of oral corticosteroids were significantly associated with osteoporosis in these patients.IntroductionChronic obstructive pulmonary disease (COPD) is becoming an increasingly serious and prevalent issue worldwide. The treatment of COPD with long-term steroid use may cause osteoporosis and have significant influences on disability and mortality. However, few studies have evaluated the association between ...
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Erratum to: Clinical utility of routine laboratory testing to identify possible secondary causes in older men with osteoporosis: the osteoporotic fractures in men (MrOS) study
(Source: Osteoporosis International)
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Erratum to: Serum creatine kinase isoenzymes in children with osteogenesis imperfecta
(Source: Osteoporosis International)
Source: Osteoporosis International - January 1, 2017 Category: Orthopaedics Source Type: research

Effect of progressive high-impact exercise on femoral neck structural strength in postmenopausal women with mild knee osteoarthritis: a 12-month RCT
AbstractSummaryIt is uncertain whether subjects with mild knee osteoarthritis, and who may be at risk of osteoporosis, can exercise safely with the aim of improving hip bone strength. This RCT showed that participating in a high-impact exercise program improved femoral neck strength without any detrimental effects on knee cartilage composition.IntroductionNo previous studies have examined whether high-impact exercise can improve bone strength and articular cartilage quality in subjects with mild knee osteoarthritis. In this 12-month RCT, we assessed the effects of progressive high-impact exercise on femoral neck structural...
Source: Osteoporosis International - December 29, 2016 Category: Orthopaedics Source Type: research

Unique effects of energy versus estrogen deficiency on multiple components of bone strength in exercising women
AbstractSummaryMany female athletes are energy and/or estrogen deficient, but the independent effects on bone health have not been isolated. Energy deficiency was detrimental at the tibia while estrogen deficiency was detrimental at the radius. Nutrition must be considered alongside menstrual recovery when addressing compromised bone health in female athletes.IntroductionThe purpose of this study was to describe volumetric bone mineral density (vBMD), bone geometry, and estimated bone strength in exercising women (n = 60) grouped according to energy status (energy replete (EnR:n = 30) vs. energy deficie...
Source: Osteoporosis International - December 28, 2016 Category: Orthopaedics Source Type: research