Clinical and biological parameters associated with fracture recurrence according to fracture liaison service dataset
ConclusionOur study showed that recurrent fracture occurs rapidly after the index fracture and that rheumatological and therapeutic managements are not sufficient, mainly because of cognitive disorders or patients ’ refusal impairing the patients to benefit from specialized management. (Source: Osteoporosis International)
Source: Osteoporosis International - August 8, 2023 Category: Orthopaedics Source Type: research

Age- and dose-dependent effect of statin use on the risk of osteoporotic fracture in older adults
ConclusionsOur results showed that statin use was associated with significant reduction in the risk of osteoporotic fractures in general older population. (Source: Osteoporosis International)
Source: Osteoporosis International - August 8, 2023 Category: Orthopaedics Source Type: research

Clinical and biological parameters associated with fracture recurrence according to fracture liaison service dataset
ConclusionOur study showed that recurrent fracture occurs rapidly after the index fracture and that rheumatological and therapeutic managements are not sufficient, mainly because of cognitive disorders or patients ’ refusal impairing the patients to benefit from specialized management. (Source: Osteoporosis International)
Source: Osteoporosis International - August 8, 2023 Category: Orthopaedics Source Type: research

The association between proton pump inhibitors and hyperparathyroidism: a potential mechanism for increased fracture —results of a large observational cohort study
This study evaluated the relationship between PPI use and hyperparathyroidism in older adults.MethodsParticipants were from the TUDA study, a large cross-sectional cohort of older Irish adults. Participants with an estimated glomerular filtration rate (eGFR)  <  30 ml/min and serum calcium >  2.5 mmol/l were excluded to avoid hyperparathyroidism due to chronic renal disease and primary hyperparathyroidism. Hyperparathyroidism was defined as a parathyroid hormone (PTH) >  65 pg/ml. Multivariate regression models were used to analyse the relationship between PPI use and hyperparathyroidism.ResultsA to...
Source: Osteoporosis International - August 2, 2023 Category: Orthopaedics Source Type: research