The incremental risk of fragility fractures in aging men
ConclusionIn men without a pre-existing history of osteoporosis, the risk of fragility fractures starts to increase after the age of 70. Further work building upon these data may help to identify a specific age at which routine bone health screening in males can help to minimize fractures and their associated morbidity and mortality. (Source: Osteoporosis International)
Source: Osteoporosis International - November 8, 2023 Category: Orthopaedics Source Type: research
Effect of educational intervention on preventing osteoporosis in postmenopausal women
ConclusionsThe theory of planned behavior affected nutrition and walking performance in osteoporosis prevention of subjects. This theory can be used as a framework for designing and performing educational interventions for preventing osteoporosis and promoting women ’s health. (Source: Osteoporosis International)
Source: Osteoporosis International - November 8, 2023 Category: Orthopaedics Source Type: research
The incremental risk of fragility fractures in aging men
ConclusionIn men without a pre-existing history of osteoporosis, the risk of fragility fractures starts to increase after the age of 70. Further work building upon these data may help to identify a specific age at which routine bone health screening in males can help to minimize fractures and their associated morbidity and mortality. (Source: Osteoporosis International)
Source: Osteoporosis International - November 8, 2023 Category: Orthopaedics Source Type: research
Pre-operative bone quality deficits and risk of complications following spine fusion surgery among postmenopausal women
ConclusionWomen with smaller bones, thinner cortices and procedures involving a greater number of vertebrae were at highest risk for post-operative complications, providing insights into surgical and skeletal risk factors for complications in this population. (Source: Osteoporosis International)
Source: Osteoporosis International - November 7, 2023 Category: Orthopaedics Source Type: research
Forearm bone mineral density predicts screw loosening after lumbar fusion similar to lumbar Hounsfield unit value in patients with lumbar spondylolisthesis
ConclusionsThe forearm BMD was an independent risk factor for loosening of the lumbar pedicle screws. The forearm BMD was a valid predictor of pedicle screw loosening in patients undergoing lumbar fusion, as was the CT HU value. (Source: Osteoporosis International)
Source: Osteoporosis International - November 3, 2023 Category: Orthopaedics Source Type: research
Vaccination against COVID-19 reduced the mortality risk of COVID-positive hip fracture patients to baseline levels: the nationwide data-linked IMPACT Protect study
ConclusionVaccination was associated with lower COVID-19 infection risk. Vaccinated COVID-positive patients had a similar mortality risk to COVID-negative patients, suggesting a reduced severity of infection. This study demonstrates the efficacy of vaccination in this vulnerable patient group, and presents data that will be valid in the management of future outbreaks. (Source: Osteoporosis International)
Source: Osteoporosis International - October 28, 2023 Category: Orthopaedics Source Type: research
Understanding the long-term impact of incident osteoporotic fractures on healthcare utilization and costs in Korean postmenopausal women
ConclusionOF imposes a substantial and sustained economic burden on women, resulting in an approximately twofold increase in the cumulative cost over 5 years compared to women without fracture, which highlights the need for early diagnostics and treatment of osteoporosis. (Source: Osteoporosis International)
Source: Osteoporosis International - October 25, 2023 Category: Orthopaedics Source Type: research
Isoflavone intervention and its impact on bone mineral density in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials
ConclusionThis systematic review and meta-analysis suggests that isoflavone interventions, especially those containing genistein of at least 50 mg/day, can effectively enhance BMD in postmenopausal women. (Source: Osteoporosis International)
Source: Osteoporosis International - October 25, 2023 Category: Orthopaedics Source Type: research
Performance of FRAX in older adults with frailty: the Framingham Heart Study
ConclusionFRAX may have been less able to identify frail individuals at risk for fracture, as compared with individuals without frailty, unless information on BMD is available. This suggests that BMD captures features important for fracture prediction in frail persons. Future fracture prediction models should be developed among persons with frailty. (Source: Osteoporosis International)
Source: Osteoporosis International - October 24, 2023 Category: Orthopaedics Source Type: research
Growth hormone and testosterone delay vertebral fractures in boys with muscular dystrophy on chronic glucocorticoids
ConclusionGH and testosterone each decreased VF risk in patients independent of or in combination with ZA, respectively. (Source: Osteoporosis International)
Source: Osteoporosis International - October 23, 2023 Category: Orthopaedics Source Type: research
Radiomorphometric indices of the mandible as indicators of decreased bone mineral density and osteoporosis – meta-analysis and systematic review
AbstractThis review aims to evaluate the accuracy of various mandibular radiomorphometric indices in comparison with DEXA BMD measurements in the diagnosis of osteopenia and osteoporosis based on a meta-analysis of the sensitivity and specificity of the indices. PRISMA statement was followed. The materials for analysis were collected in August 2023 by searching three databases: PubMed Central, Web of Science, and Scopus. The selection of studies consisted of three selection stages, and 64 articles were finally obtained. Quality assessment was performed with the QUADAS-2 tool, and the general methodological quality of retri...
Source: Osteoporosis International - October 23, 2023 Category: Orthopaedics Source Type: research
Comparison of anti-fracture effectiveness of zoledronate, ibandronate and alendronate versus denosumab in a registry-based cohort study
ConclusionsWhen adjusting for disease severity, denosumab was associated with significantly greater risk reduction than alendronate and ibandronate for vertebral fractures. No difference in fracture risk reduction was found between zoledronate and denosumab. (Source: Osteoporosis International)
Source: Osteoporosis International - October 22, 2023 Category: Orthopaedics Source Type: research
A genome-wide genomic score added to standard recommended stratification tools does not improve the identification of patients with very low bone mineral density
ConclusionOur results suggest adding a GS to a CRF model does not improve prediction. However, we noticed that the GS performed equally or above individual risk factors in discrimination. Clinical risk factors combined showed superior discrimination to individual risk factors and the GS, underlining the value of combined CRFs in routine clinics as a stratification tool. (Source: Osteoporosis International)
Source: Osteoporosis International - October 22, 2023 Category: Orthopaedics Source Type: research
